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The Nutrient Connection – How Micronutrients Could be at The Root of Your HPV.

The Nutrient Connection – How Micronutrients Could be at The Root of Your HPV.

Adrienne Hill-Strathy
When many of us think of the health benefits of food proteins, fats, and carbohydrates come to mind. These macronutrients make up the general composition of our foods but within them lie additional health-promoting compounds called micronutrients. Micronutrients include trace minerals and vitamins that support the normal growth and development of living organisms. Without them, body systems like the immune system, nervous system, and digestive system can become impaired. Many individuals are deficient in micronutrients. This can be due to low intake of dietary sources like fruits and vegetables and high intake of processed and nutrient-poor foods. Additionally, it is thought that the micronutrient quality of our fresh food has declined in recent years due to industrial agricultural production. This micronutrient deficiency may be at the root of why some people struggle to eradicate HPV infections compared to others who clear the virus more easily. Several micronutrients have been specifically found to be low in individuals with HPV and cervical dysplasia - we’ll outline them below. Portrait of female gatherer gathering organic vegetables with a wicker basket at orchard The Key Players Folate – Vitamin B9 Most people know of folate as an important nutrient for fetal development that should be taken during pregnancy. In addition to supporting a healthy pregnancy, Folate also plays a role in DNA production and red and white blood cell formation, and also plays an important role in HPV. When folate levels are low, the body has trouble maintaining a process called methylation. Methylation helps support cardiovascular, neurological, and reproductive health. When the process is impaired, it can increase levels of an inflammatory compound called homocysteine. This compound can increase the risk of heart disease and impact gene regulation that helps regulate cancer cell growth. There is a strong association found between folate deficiency and cervical dysplasia. Several studies have found that high blood levels are associated with a lower risk of cervical dysplasia and HPV and increased risk with low blood folate. Studies have also demonstrated that supplementation with folate may reduce the risk of cervical cancer.  Low dietary intake of folate may not be solely to blame for deficiencies. Some individuals have SNP’s in their genetic pathway that prevents them from converting dietary folate into its active form. These individuals may have higher levels of homocysteine and an increased risk of disease. How to get your dose? Foods that contain folate include leafy greens, brussel sprouts, broccoli, and chickpeas. Folate can also be supplemented. The recommended daily intake of folate is 400 micrograms. Lycopene and Carotenoids- Vitamin A Vitamin A is derived from dietary intakes of those red, orange, and green-colored vegetables rich in lycopene and carotenoids. This vitamin also appears to play a role in cervical health. Studies evaluating dietary intake and blood levels of Vitamin A found higher intake was associated with a reduced risk of cervical cancer. Whereas low dietary intake of carotenoids is associated with an increased risk of persistent HPV infections. How to get your daily dose? To get more lycopene and carotenoids into the diet, aim for 6-8 servings of leafy greens, orange, red and yellow vegetables per day. Foods rich in lycopene and carotenoids include: carrots, squash, tomatoes, broccoli, and red peppers. A dosage of 3000 mcg per day is recommended. Please note that Vitamin A should not be taken if pregnant, as excess stores can build up and cause birth defects. Selenium Selenium is another trace mineral that we must obtain from our diet. Selenium is important for thyroid function, reproductive health, and keeping the immune system running. Many individuals are low in selenium due to the reduced soil quality of our foods. Low levels have been found to increase rates of cervical dysplasia. Selenium deficiency is thought to allow viral strains to mutate and progress. How to get your daily dose? Selenium is found in high doses in brazil nuts. 3 nuts per day are adequate to reach the daily recommended dose of 200 mcg. Oysters have also been found to contain selenium. Vitamin C Who doesn’t love vitamin C? A powerful antioxidant that plays a role in many functions in the body. Vitamin C is important for immune system function, which is why we have all associated oranges and lemons with preventing colds and flu. Vitamin C also supports collagen production, iron absorption, and fuels and protects our cells. Studies have found that higher intake of Vitamin C was associated with lower rates of HPV persistence compared to lower intake. Dietary supplements of Vitamin C were also found to reduce the risk of Cervical dysplasia in high-risk HPV infections. How to get your daily dose? Foods like kiwis, red peppers, broccoli, citrus fruits, apples, and strawberries are high in vitamin C. The recommended daily intake is 75 to 90 milligrams. However, intake of up to 2000 mg a day is considered safe. Vitamin E Finally, Vitamin E deserves a mention - this vitamin is another powerful antioxidant found to protect against DNA damage and oxidative stress. Vitamin E may have anti-cancer effects. A meta-analysis reviewing the relationship between vitamin E intake and blood levels of vitamin E has found the higher levels of vitamin E, the lower level of cervical dysplasia. How to get your dose? Vitamin E is found in foods like sunflower seeds, almonds, peanuts, pumpkin, beet greens, spinach, and red bell pepper. The recommended daily intake is 15 milligrams per day. Receiving our nutrients from foods is always the best method, however, it isn’t always easy to get our daily dose. That is why Papillex formulated its supplement with this research in mind to provide one supplement to meet all of your needs!
Sep 06, 2021
4 min read
Condyloma Acuminatum: Genital Warts

Condyloma Acuminatum: Genital Warts

Adrienne Hill-Strathy
Condyloma Acuminatum is a fancy way of saying genital warts - a common symptom of a Human Papillomavirus (HPV) infection. Genital warts can be alarming and irritating. If you are experiencing genital warts, you are probably wondering how you can get rid of them. Is there anything you can do naturally? In this blog, we provide ways to respond to genital warts naturally, both internally and externally. The HPV family While most of the focus on HPV surrounds cervical cancer, the HPV family includes over 100 different viral strains, each having a slightly different impact on the body. HPV is responsible for common and plantar warts found on the hands and feet, as well as genital warts that grow around the vulva, vagina, penis, and scrotum. Only a few of the strains of HPV have the potential to become carcinogenic, causing cervical, oral, and anal cancers.  90% of genital warts are linked to HPV strains 6 and 11: These strains are considered “low risk” because they rarely develop into cancer. 70% of cervical cancers are caused by HPV strains 16 and 18: These strains are known as the highest risk strains and can progress into cancer. What do genital warts look like? Genital warts look like soft, fleshy growths. They may appear as a single or in multiples, some describe them as looking like cauliflower. Genital warts can be irritating but are rarely painful. Genital warts can affect both men and women. The estimated 5-year prevalence of genital warts is 1.3% in men and 1.7% in women. Warts typically emerge around the genitals a few weeks to two to three months after infection. HPV is easily transmitted from one individual to another through skin-to-skin contact, most commonly through sexual activity. Even if the individual has no symptoms or the warts have gone away, they may still be able to transmit HPV. If you suspect that you have genital warts, we recommend seeking advice from a medical professional. Other STIs, like herpes or syphilis, can present with similar symptoms and may warrant further treatment. The lesions may also be something harmless like a mole, ingrown hair, or skin tag - so it’s always better to check! Can I naturally respond to genital warts? Most people’s immune systems will naturally clear HPV infections in anywhere from a few months to a few years. The immune system includes several immune molecules like natural killer cells, cytokines, and macrophages that identify and eradicate viral infections. The immune system also keeps cancer cell growth in check through a process of tumor cell identification and cell death.  A few natural compounds have been found to enhance these immune players, leading to viral clearance. How to respond internally Green tea extract: Green tea extract is a key player when it comes to antiviral support. Green tea is high in compounds called polyphenols that benefit the immune system. Two polyphenols, epigallocatechin gallate (EGCG) and polyphenol E are effective at treating cervical lesions and warts caused by HPV. Drinking green tea as well as supplementation has been found to contribute health benefits and support wart clearance. If drinking tea isn’t your thing or you want to amplify your dose, Papillex supplies the recommended daily serving of green tea to support the immune system. Diet: It is estimated that 80 percent of the immune system is located in the gut. So what we eat and put into the body plays an important role in our immune defense. Eating a diverse array of fruits and vegetables provides ample micro and macronutrients. Amino acids obtained from proteins are essential for immune function as well as probiotics and fiber to support the intestinal microbiome. We also recommend trying to limit sugar, which can act as an immunosuppressant. AHCC: Emerging research on a medicinal mushroom extract called AHCC may support the immune system in eradicating HPV that causes genital warts. AHCC has been found to enhance the production of NK cells and cytokines, known for their role in viral clearance. The extract has not been clinically tested on genital warts but has been found to help eradicate persistent high-risk HPV infections in individuals with cervical dysplasia. How to respond externally Topical treatment for genital warts: Conventional treatment offers several prescription chemical treatments that can be applied topically. Some topical treatments include Podofilox, a gel solution with active podophyllin, has been found to prevent local irritation, and Imiquimod, a topical immune modifier that comes in single-use packets. In addition, there are natural solutions on the market. Green Tea Extract: Green tea extract has also been shown to have benefits when applied topically. The FDA has approved a standardized extract of green tea leaves for topical use on warts. The extract contains 15% catechins, the potent polyphenols found in green tea. Research evaluating the use of green tea extract topically found it to be effective and safe. The study evaluated a 10% green tea catechin ointment on over 100 adults with genital warts. The findings showed that those that used the green tea were 2-fold more effective at clearing existing warts and preventing recurrence 12 weeks after treatment. Tea tree oil: Tea tree is an antimicrobial herb that can be applied topically with a carrier oil such as coconut oil. Tea tree oil should not be taken internally or applied to the vaginal canal. One case report evaluating the use of tea tree oil twice daily with a carrier oil found clearance within 10-20 days for warts to disappear completely. More research is needed to determine the effectiveness on genital warts in larger, randomized clinical trials.  Bottom Line Few people are willing to talk about their experience with genital warts, and this stigma makes it difficult to know what to do. We hope this article gives you an assurance that genital warts are harmless and mostly self-limiting. If you are having trouble clearing genital warts, there are natural ways to respond both internally and externally. When in doubt, we always recommend you consult with a trusted natural health practitioner to find what works best for you.
Aug 23, 2021
5 min read
Amino Up Chemical Co.: The Makers of AHCC®

Amino Up Chemical Co.: The Makers of AHCC®

Adrienne Hill-Strathy
When it comes to medicinal mushrooms, there isn’t one quite like AHCC®.  AHCC® stands for Active Hexose Correlated Compound, a unique mushroom extract cultured from the shiitake mushroom species. Medicinal mushrooms have been used for centuries in Eastern Medicine to prevent and treat illness. These ancient practices are now being supported by clinical research studies, leading to growth in innovative products that optimize the compounds’ therapeutic benefits. The Amino Up Chemical Co. has spurred innovation in the mushroom world by creating an extract with potent immune-modulating activities. But first, how are mushrooms medicinal?  Before we dive into AHCC® - let’s start with the basics. How can mushrooms be medicinal? We are all familiar with the common white mushrooms, portobello, and oyster mushrooms, but most of us reserve them for our forks, not our medicine cabinets. Out of 14,000 species of fleshy fungi, numerous types have been found to have nutritional and therapeutic effects.  Edible mushrooms contain beneficial nutritional compounds such as B vitamins, zinc, potassium, copper, and magnesium. Mushrooms are also a great source of fiber and can protect against cellular damage due to their concentration of antioxidants.  Medicinal mushrooms contain compounds that support bodily functions that protect against aging and disease. The medicinal mushrooms are not always edible and require advanced techniques to extract the desired medicinal component so that they can be uptaken by the body.   Amino Up Chemical Co. The AHCC® compound is manufactured by a company called Amino Up Chemical Co. in Sapporo, Japan. Amino Up has been manufacturing innovative functional ingredients powered by plants since the 1970s. In 1989 the company debuted the cultured Lentinula Edodes Extract, also known as AHCC®. Today, over 30 clinical trials have investigated the use of Amino Up’s AHCC® in response to viral infections and cancers through its immune-modulating activity. Not only has the compound been found to be supportive in viral infections and influenza, but also a complementary therapy in breast, liver, pancreatic, and colon cancer. The findings provide evidence that AHCC® can improve quality of life and prolong survival.  How was AHCC® created?  AHCC® wouldn’t be the potent immune support that it is without the company's unique manufacturing process.  AHCC® was derived through an extensive screening and manufacturing process. The company screened a vast range of basidiomycetes mushrooms to extract the specialty strain of mycelia used to produce AHCC®. How is AHCC extracted? AHCC® is derived from a mixture of components derived from the cultured mycelia. Mycelia are root-like hairs of the mushroom that grow in wood or soil. AHCC® is derived from mycelia of the Lentinula edodes mushroom, also known as shiitake mushroom. These root-like hairs are broken down into tiny molecules. The final product is taken in capsule or powdered form. Not all supplements are created equal. The source, quality, and effectiveness of a supplement are all important when we are talking about our health. Amino Up uses a standardized extract of the cultured Lentinula edodes mycelia to ensure the highest quality and product consistency. The process regularly undergoes quality and safety control. AHCC® is extracted with the environment in mind by regularly conducting studies into the biodiversity around its property. Amino Up aims to live in harmony with the environment and wildlife.  Why take AHCC®? What makes the extract unique is its concentration of glucans. Normally, medicinal mushrooms contain polysaccharides called beta-glucans. Beta-glucans are known to modulate the immune system and can trigger immune molecules to amplify a response. The cultured extraction process of AHCC® derives another glucan called acylated alpha- 1,4 glucans. These glucans have a very small molecular weight, about 95% smaller than beta-glucan. The lower molecular weight is easier for the digestive system to absorb, helping to directly impact the immune system.  Together this combination acts as immune-modulating agents, helping strengthen the defense against infections and chronic disease.  Look out for products that are not the real AHCC® Clinical research evaluating the use of AHCC® has used this proprietary extract. These studies have researched AHCC® in cancer therapy, antivirals, and immune support.  AHCC® sold without the trademark (TM) or registered trademark (R) symbol next to the “AHCC” is not the clinically researched form of AHCC. Some supplement companies will use the full name – Active Hexose Correlated Compound. This implies that the compound has not been verified by the current clinical research and does not contain the acetylated alpha-glucans found to have an immune-modulating effect.  There is always shroom to grow We are excited by the ever-evolving ways we are learning to use plants and fungi as medicine. As the research unfolds, so too will our application and development of products like AHCC® to help promote longevity and health. As always, we recommend consulting with a natural health practitioner before supplementing AHCC®. The compound is safe and effective in most individuals, but it is always good to check if it is the right choice for you. 
Aug 09, 2021
4 min read
Letting Go: The Shame of HPV

Letting Go: The Shame of HPV

Adrienne Hill-Strathy
Shame is the intensely painful feeling or experience of believing that we are flawed, and therefore unworthy of love and belonging (Brene Brown, 2012). We all have known and have experienced the discomforting wash of shame at some point in our lives. Under our shame often lies our rooted beliefs and experiences that tell us we are bad. Shame differs from guilt in that our guilt tells us we did something bad, our shame tells us that we are bad. Shame is intense and can lead to secrecy, silence, and judgment. STI’s and Shame From a young age, we have been taught to fear sexually transmitted infections (STIs). Sexual health education, media, and society have all painted the picture that STIs are dirty and disgusting - by that logic, if we catch one, we must be dirty and disgusting, too.  Because HPV is an STI, we often feel ashamed of our diagnosis.  Holding onto shame can prevent us from living a healthy life, and can contribute to stress and unhealthy behaviors that impair our immune system. Letting go of the shame associated with HPV may be foundational to our healing. In this article, we share a few ways you can reframe your narrative to understand that HPV isn’t something to be ashamed about. By releasing our shame, we make space to empower ourselves and others. How to Let go of Shame To let go of the shame of HPV, it is important to clarify a few things about the virus, how it is contracted, and how prevalent it is - with this information, we can begin to change our narrative. Creating a new narrative: the truth about HPV HPV is a virus.  As humans, we are naturally exposed to viruses and other pathogens that live in our environment - this is a part of life. Strains of the HPV family have an affinity for skin tissue in and around the genital or mouth areas. The virus is passed on through skin-to-skin contact with an infected individual. HPV is so common that an estimated 80 percent of women will contract a strain of HPV in their lifetime.  Once infected, the virus makes a home within the human tissue cells. In most cases, the immune system will identify and suppress the virus activity over time leading to no symptoms or complications. In some cases, the virus may proliferate and slowly cause cellular dysplasia that can lead to cervical cancer over many years. Given the large number of HPV strains and high transmission rate of the virus, the best way to avoid exposure includes abstaining from sexual activities or limiting your number of sexual partners. Sexual activity is a significant part of the human experience.  Asking you to suppress your sexuality would be like asking you to stay in your house for the rest of your life to avoid catching a cold. We can aim to prevent infection by avoiding risk factors, but we don’t want to miss out on life! Instead of staying at home, our body has an innate system called the immune system, which we rely on to support and protect us from infection and disease. We can take preventative action by making sure this system is up and running efficiently to protect us against viruses. Now that we understand a little more about the virus, it is time to foster a little empathy. Fostering empathy for yourself: If the root of our shame lies in our feelings of being unworthy of love and belonging, letting go of shame requires a healthy dose of empathy. Empathy involves showing compassion and kindness to ourselves, which can feel unnatural and uncomfortable at first. Imagine talking to yourself like you would talk to a young child or a close friend. How would you speak to them in a similar situation? I would imagine it is different from how you talk to yourself, because we are often harshest to ourselves. Remind yourself that you are not to blame, you are not unworthy, and you are deserving of care. Self-compassion and empathy is a continuous practice.  Name it to tame it One of the most powerful tools we can use to reduce our shame is to talk about it. When we can name our shame, we tame our shame.  So many women suffer the HPV diagnosis in silence but find that when they do speak up they can connect with so many others who are experiencing the same thing. Speaking up about our shame is a vulnerable and emotional risk. With that risk lies the power of vulnerability - it creates space for others to feel less afraid, less alone, and less ashamed. When we don’t talk about these things, we can unintentionally breed shame. Try opening up to someone you trust. Turn to a trusted friend, family member, or counselor - someone who can hold space for you and just listen. We know that talking to a partner can be scary and intimidating, but have found that many who have opened up about their sexual health with their partners often find it brings them closer. Speaking your truth also allows for a chance to practice being your most honest and authentic self. Shame has a powerful weight on each of us, and we all experience it at some point. Often, the shame associated with HPV is rooted in our misunderstanding of the virus and the narrative we have created around contracting sexually transmitted infections.  Remember that shame also does not help you and it does not help others. Be kind to yourself and show yourself compassion - your vulnerability can give others the courage and strength to let go of shame as well. Sources: https://www.ted.com/talks/brene_brown_listening_to_shame?language=en
Jul 26, 2021
4 min read
Mushrooms for Inflammation

Mushrooms for Inflammation

Adrienne Hill-Strathy
Let’s talk about inflammation. Many have deemed inflammation the driver of all chronic diseases - but, inflammation is crucial to our survival and bodily protection. We need inflammation to heal.  So, what is the balance? And how can we find it?  This blog covers all of that and more - keep reading for all things inflammation. Inflammation- friend or foe? Inflammation is the immune system’s first line of defense when fighting off pathogens like bacteria and viruses and helps us heal from injury. The inflammatory response plays a crucial role in combating infection and repairing tissue damage. Without inflammation, the body couldn’t heal. Several immune molecules play a role in inflammation, including macrophages, fibroblasts, mast cells, and dendritic cells. These molecules circulate in the blood until they pick up on invaders or cell damage to direct their response. With all of that said, chronic activation of the inflammatory response is at the root of many diseases. Our understanding of the connection between inflammation and disease has grown, and so have our tools to balance its response. Medicinal mushrooms are one way we can support the immune system in modulating the inflammatory response. Types of inflammation: Acute inflammation: Acute inflammation is the first player to act in the immune response. A scrape on your knee that turns red and hot, a runny nose, or a fever are all the body’s natural ways of healing. We have all experienced these acute inflammatory stressors and thank our body for its effective response. Chronic inflammation: Chronic inflammation occurs when the immune system is constantly triggered. Instead of healing the body, the immune system creates too many pro-inflammatory molecules, like tumor necrosis factor (TNF), interleukins (ILs), prostaglandins, and free radicals - this excess causes cell damage and creates health issues.  Many factors contribute to chronic inflammation. Inflammation may be triggered by stress, foods, toxic chemicals, heavy metals, and infections. Diet plays a large role because 70-80 percent of the immune system is located in our gut. What we eat directly interacts with the immune system and can initiate an inflammatory response. How do I know if I’m chronically inflamed? Chronic inflammation can be hard to detect and can build up over time. Symptoms such as weight gain, fatigue, moodiness, pain, skin problems like psoriasis and eczema, allergies, and autoimmune conditions may indicate chronic inflammation. You can also measure inflammation through blood tests. C-reactive protein (CRP) is a common inflammatory marker that can be measured in the blood. The optimal range of CRP is < 0.5 mg/L.  Homocysteine is another inflammatory amino acid linked to heart disease and other inflammatory conditions. The optimal range is <7 Umol/L. How can I decrease inflammation? Now that you know a bit more about optimal and chronic inflammation - what can you do?  Here is where the mushrooms step in. Medicinal mushrooms and inflammation Mushrooms have been used for centuries for their therapeutic effects on the body. Mushroom extracts have been used as immune modulators and for their anticancer, antibacterial, and antiviral properties. Medicinal mushrooms contain some of our most potent anti-inflammatory compounds. Medicinal mushrooms contain active compounds that can modulate the inflammatory response. Mushrooms are rich in polysaccharides, phenolic and indolic compounds, mycosteroids, and fatty acids as well as other vitamins and biometals. During chronic inflammation, the immune system is overproducing inflammatory mediators, leading to cell damage. The bioactive compounds found in mushrooms can reduce and suppress the production of inflammatory mediators through downregulating certain genes. This downregulation dampens the immune response, creating homeostasis and preventing chronic disease. The powder of polysaccharides Polysaccharides are one type of bioactive compound found in mushrooms. These polysaccharides inhibit inflammatory molecules including, IL-6, prostaglandins, and leukotrienes. Glucans are one type of polysaccharide found to adjust the immune system by binding to receptors in the digestive tract and activating the immune response. The glucans stimulate the production of immune molecules such as natural killer cells, cytokines, and T helper cells. These immune molecules signal the rest of the immune system to kick into gear.  What mushrooms can help inflammation: Reishi: Also called the mushroom of immortality, Reishi is rich in bioactive compounds including fatty acids, polysaccharides, and peptides found to inhibit inflammation. The polysaccharides found in Reishi may inhibit cancer cell growth and have anti-inflammatory properties with melanoma and breast cancer.  Chaga: Chaga mushrooms have also been found to have a potent anti-inflammatory effect. The mushroom has been found to have anti-inflammatory properties on mast cells and histamine responses. Histamine and mast cells are released in response to tissue damage and other inflammatory conditions and affect the microvasculature.  AHCC: Stands for Active Hexose Correlated Compound, a mushroom extract that contains both alpha and beta-glucans that modulate the immune system. AHCC is a potent immune modulator that stimulates natural killer cells, cytokine, and macrophages. The extract has been evaluated as general immune support as well as an adjunctive in the treatment of cancers and viral infections. Of course, supporting a healthy inflammatory response involves more than just a mushroom supplement. Diet, stress, environmental toxins, etc. also play a vital role. It is important to assess your lifestyle and make adjustments based on your specific risk factors. We recommend including a few mushrooms in your daily routine to offer extra immune support and keep you in balance.  
Jul 12, 2021
4 min read
AHCC® and Genital Warts

AHCC® and Genital Warts

Adrienne Hill-Strathy
Genital Warts are one symptom of the Human Papillomavirus (HPV). Warts are caused by specific strains of the HPV family. These strains cause soft, fleshy, and often irritating growths around the genital areas. If you have developed genital warts, you are probably wondering, “how do I get rid of them?” and “what does this mean for my health?” In this blog, we break down all things genital warts, as well as provide information about a new medicinal mushroom compound called AHCC®. AHCC® has been found to support the immune system and eradicate viral infections like HPV.  What are Genital Warts? Genital warts usually appear on the vulva, vagina, scrotum, or penis a few weeks to two to three months after exposure to an HPV infection. The warts tend to be soft, fleshy, skin-colored, or appear as white bumps. They may grow in singles or multiples, sometimes appearing as a cauliflower-like growth. While genital warts can be itchy, annoying, and persistent, they are harmless. How Did I Contract Genital Warts? The HPV family includes over 100 different viruses that commonly infect humans. The virus is so common because it is easily transmitted through skin-to-skin contact.  Genital warts can be transmitted through sexual interaction with the vagina, anus, oral sex, or hand contact. Transmission can even occur through individuals without visible warts or symptoms. Given the ease of transmission, it is estimated that 80 percent of people will be exposed to an HPV infection at some point in their lifetime. The risk of developing complications depends on the viral strain of HPV that you have contracted.  What are the complications of contracting genital warts? Fortunately, the strains of HPV that cause genital warts do not cause cancer. The strains of HPV associated with warts are considered low-risk. HPV tends to arise two to three months after infection and can last anywhere from a few weeks to a few years. High-risk strains that are often asymptomatic can eventually progress into cancer. It is important to note that contracting one strain of HPV does not make you immune to contracting other strains of HPV. Even if you have low-risk HPV, you can still be exposed to high-risk strains and should follow your physicians’ recommendations and receive regular testing. You can also pass the infection on to another person even once the warts have gone away. Can genital warts be treated? If you have recently noticed an outbreak of genital warts - what can you do to get rid of them? HPV and genital warts can be treated. Viruses and other pathogens that affect humans are suppressed by the immune system. Immune molecules such as natural killer cells, cytokines, and macrophages play a role in identifying and eliminating these foreign invaders. One way to naturally enhance the function and production of the immune system is through medicinal mushrooms. AHCC® and genital warts Active hexose correlated compound, or AHCC®, is a medicinal mushroom extract with immune-modulating and antioxidant activities. AHCC® has been researched for its use in supporting immune function in cancer treatment, viral infections, and enhancing immune function. Studies have found AHCC® to increase the natural killer cell and cytokine production, allowing for greater activation of the immune system. AHCC® also enhances T-cell and macrophage production, helping eradicate and eliminate invaders. AHCC® has been clinically researched as immune support for people suffering from persistent high-risk HPV infections. Dr. Judith A. Smith, of the University of Texas, has led two clinical trials of the use of AHCC® in people with HPV. The studies have evaluated a dose of 1 and 3 grams of AHCC® daily in high-risk HPV-infected individuals. The results of both studies have found AHCC® to have statistical significance in eradicating HPV infections compared to placebo.   No research studies have specifically evaluated AHCC® on genital warts. However, the underlying immune system support is important for clearing viral infections because it is the first to respond to and identify threats to the body for elimination.  What else can I do? There are certain lifestyle changes you can make to reduce your risk of infection: Quit Smoking and reduce alcohol: Smoking cigarettes impacts nearly every tissue in the body. No safe limit is recommended for use.  Reduce alcohol intake: Drinking alcohol can suppress the immune system. If you choose to drink, aim for less than 2-3 glasses per week.  Long-term use of oral contraceptives: Oral contraceptives have been linked to an increased risk of cervical cancer. Amp up your diet: Eating a nutrient-dense diet full of fruits and vegetables. Individuals who consumed more vegetables are less likely to have HPV.  Green tea extract: Green tea extract has also been shown to inhibit the development of HPV warts and cervical lesions.
Jun 28, 2021
4 min read
How To Prepare For a Colposcopy Exam

How To Prepare For a Colposcopy Exam

Adrienne Hill-Strathy
Scheduling a colposcopy exam can come with a flood of anxieties - will it be uncomfortable? What if you receive an abnormal Pap? What comes next? If you’re feeling these concerns, you are not alone. We are here to equip you with a few ways to prepare your body, mind, and cervix for your next appointment.  If you have never had a colposcopy before, here is a little bit about what you can expect in the exam.  How To Prepare For Your Next Colposcopy Appointment Pre-Appointment: Feeling prepared for your appointment can reduce some of your anxieties and fears, we recommend: Scheduling your Pap appointment at an appropriate date and time can be helpful to reduce the stress leading up to the exam. Aim to schedule the appointment for the morning so you won’t increase your anxiety by spending the entire day thinking about it. It can also help to pick a day when you have fewer commitments. With less to do that day, you can schedule some time to do something nice for yourself after your appointment. Write a note for the appointment including important information and any questions you may have. For example: The last date of your period and cycle length Any medications you are taking Additional diagnosis Plans to conceive Remind your doctor of your unique situation. Jot down any questions you might have about your appointments, test results, and procedures. Knowing when and what is being tested over the coming months and year can help you plan and feel more prepared.  Take some time to get into your body. Doing something that engages your physical body or senses can help get you out of your mind and into your body. We recommend: Try a morning meditation Go for a walk Practice yoga Listen to relaxing music Inhale some essential oils Release your fears. Writing or speaking about your fears can be a helpful way of releasing them from inside of us. Take a few minutes to notice and acknowledge the thoughts you are having. Are they true? Are they helpful? Can you reframe your thinking? Create a mantra. Creating a mantra to repeat to yourself when anxious thoughts arise is another helpful technique to release anxiety. Something as simple as, “I am healthy, I am strong, I trust myself” can help bring us back into an empowered mindset.  At the Appointment: Share your questions, anxieties, and fears with your doctor. Most doctors understand the stress of the situation and voicing your fears can help them reassure you about the process and your health.  Bring a token with you. During the appointment, it can be helpful to have something you can hold in your hands to ease anxiety. You may want to bring a crystal, stress ring, or bracelet.  Use touch to calm the mind. Use your finger or hands to gently massage the back of your neck or wrist areas. These areas contain pressure points that can help bring us back to the present and increase feelings of relaxation.  Be your own advocate. Often, we look to authority to guide us instead of looking within. Remember that your doctors see many patients every day and despite caring for your health, they don’t live and experience your body as you do. You know your body and know what feels right or wrong. You are the best advocate for your health - so, voice something if you feel it is needed. After the Appointment: You did it! A colposcopy is hard, so be proud of showing up and making it through. Give yourself a hug and reward yourself with something you enjoy. Take a quiet bubble bath with candles, buy yourself flowers, release the tension with a sweaty yoga class, or schedule a catch-up with your most supportive friends. Do what makes you feel best. Schedule your follow-up appointments and reflect on where you want to be at that time. Are there elements of your lifestyle you want to focus on changing between now and then? Make a list of things you can do to support yourself through this time.  Obtain your results online. Many offices now offer online results. For some, it may be helpful to review your results at home before your appointment. Take time to think of any questions or concerns and allow yourself to enter your next appointment feeling informed. Unfortunately, we sometimes have to go to uncomfortable appointments because it is important for our health. In these times, we need a little extra self-care and grounding. We hope these tips provide some value and stress relief for your next visit but keep in mind that you are your own expert - your best guide is to look within!
Jun 14, 2021
4 min read
How To Supplement AHCC® for HPV

How To Supplement AHCC® for HPV

Adrienne Hill-Strathy
Natural health products are growing in popularity, likely due to their generally strong safety profiles and wide-ranging impact on the body.  Before starting any supplement, it is important to know if it’s right for you. AHCC® is a powerful immune support derived from medicinal mushrooms. Papillex has recently added AHCC® to our HPV arsenal and wanted to lay out everything you should know before jumping on this supplement train! What is AHCC®? AHCC® stands for active hexose correlated compound, a nutritional supplement derived from the medicinal mushroom, shiitake. After being used for many years in Traditional Chinese Medicine and medical practices in countries like Japan, AHCC® is recently being adopted globally for its immune-modulating activities. Several clinical research studies have found the compound to be effective as both a therapeutic and preventative immune support. Interested in learning more? We have laid out everything you need to know about supplementing AHCC® so you can decide if it’s right for you.  Is AHCC® safe? One of the magical things about medicinal mushrooms is that they are generally safe and well-tolerated in most individuals when taken in the appropriate dose. AHCC® has been tested in individuals in dosages up to 9 grams. Overall, findings have shown AHCC® to be safe with only some reports of mild nausea, headaches, and diarrhea. AHCC® has also been found to be well-tolerated alongside other medications, including being used as an adjunctive in chemotherapy. It is important to note that the compound may interfere with drugs metabolized using the CYP450 2D6 pathways and should not be combined with drugs such as doxorubicin or ondansetron.   Despite the compound’s strong safety record, there is still a lot to learn about the fungi. Research has mostly evaluated the use of AHCC® in patients with cancer, influenza, and viral infections. The compounds’ immune-boosting properties could potentially be too stimulating in individuals with immune-related disorders such as MS, Lupus, rheumatoid arthritis that present with immune activation. AHCC® Dosage for HPV  Typically, a dose of 1-3 grams of AHCC® is recommended for general immune support in patients with HPV. Higher doses of 3-6 grams daily are typically used in cancer patients. Two clinical trials, conducted by Dr. Judith A. Smith, have specifically evaluated the use of AHCC® in individuals with persistent high-risk HPV infections. The first study included ten female participants, using a dose of 3 grams daily for 5 weeks up until 6 months. The second study included another ten females but used a dose of 1 gram daily. Both groups found AHCC® to be more effective than controls at eliminating the infection, however, the 3-gram dose was slightly more effective.  How to take AHCC®? AHCC® by Papillex comes in pills of 500mg. For general use, we recommend taking 2 capsules in the morning at least 30 minutes before eating. Why take AHCC® on an empty stomach? We recommend taking AHCC® without food because most clinical studies have evaluated AHCC® on an empty stomach. We also know that taking some supplements away from food can help increase the absorption of the compound into the bloodstream, ensuring optimal therapeutic effect. However, some patients may experience nausea or have difficulty taking supplements without food. In which case, taking AHCC® with a light meal or a small amount of food will still allow for absorption. Consistency is important for the compound to have its intended effect. It can be helpful to set a designated time to take your supplements. It can also help to pair it with another daily activity, like when you brush your teeth in the morning. Setting an alarm or having your supplements in a visible, easily accessible space can also be helpful for maintaining consistency. Can I take AHCC® together with Papillex™? AHCC® and Papillex™ can be taken together for added immune support. Papillex™ helps restore nutrient deficiencies that may be low in individuals with HPV. Papillex™ also contains immune-supportive herbs like astragalus and reishi. AHCC® is a powerful immune support, providing additional support in helping identify and clear viral infections.  Duration - How long do I need to be on this supplement? AHCC® can be taken as a daily supplement in lower dosages of 1 gram per day to help support general immune function. For higher dosing of 3-6 grams, it is recommended to only supplement for 3-6 months. After 3-6 months, you can reduce the dose to 1-3 grams daily. Research studies have not evaluated the long-term use of AHCC®, therefore we cannot say whether it is safe to take for years on years.   How do you find out more and if it’s right for you? Despite the compound’s strong safety profile, we are all unique individuals.  We recommend consulting a healthcare professional before supplementing AHCC®. Naturopathic doctors, Traditional Chinese Medicine practitioners, and Functional Medicine doctors are often more informed about nutritional and herbal supplements and may be more suited to answer your questions about AHCC® and whether it is right for you.
May 31, 2021
4 min read

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