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Topical Herbs for HPV and Genital Warts

Topical Herbs for HPV and Genital Warts

Adrienne Hill-Strathy
Genital warts are a common symptom of low-risk strains of the Human Papillomavirus (HPV). Genital warts are typically harmless, however, they can cause discomfort, irritation, and distress. A lot of people are interested in natural herbs and nutrients to support their bodies against low-risk strains and warts from HPV. Herbal therapies offer attractive treatments for HPV given their strong safety profile and wide therapeutic index. Here we share some of the best ingredients and evidence to support the use of topical herbal therapies on viral infections. It should be noted that many of the studies included in the review do not specifically review HPV but other viral infections like the Herpes Simplex Virus (HSV) and influenza. The antiviral actions work similarly on the HPV, but more research is needed on topical herbal products to fully understand their use. The Ingredients Turkey tail Turkey tail is a medicinal mushroom know to have immune-modulating and energizing effects. The mushroom grows in a multicolored array on fallen trees in wooded areas of North America. The compound has been taken orally for centuries to treat respiratory conditions and has been used as an adjunctive in cancer treatment. The mushroom was found to have antiviral activities against influenza and HSV viruses in cell studies. The active compounds in turkey tail include polysaccharides called PSP and PSK. These compounds appear to act on the immune system and can inhibit the growth of cancer cells. Most people tolerate turkey tail well. The compound is considered safe, though it may cause mild gastrointestinal side effects like heartburn, constipation, and nausea when taken orally. Lemon balm Also known as Melissa officinalis, this herb comes from the mint family and has a lemon scent to it. Commonly used to improve mood, calm anxiety, and improve cognitive function, lemon balm also has antiherpetic and antiviral effects on the HSV family. Studies have found topical application of lemon balm to provide therapeutic action against recurrent herpes infections and cold sores. In one study, participants applied either lemon balm or a placebo to affected areas four times a day for five days. At the end of the five days, the participants that used the lemon balm had fewer symptoms of itching, burning, and redness. The lemon balm group also had faster healing than the placebo group. Echinacea root Echinacea is a commonly used herb for treating colds, flu, and other viral infections. The plant has anti-inflammatory, immunomodulatory, and antioxidant properties that have been used for centuries to treat various ailments. Studies find echinacea to benefit the immune system to combat viruses. Specifically, echinacea has been found to have antiviral activities against the HSV. Topically, echinacea has been found to help improve skin hydration, reduce acne and improve eczema symptoms and skin repair. Green tea extract Commonly known for its energy-boosting properties, green tea also has powerful antioxidant activity that protects against free radical damage. Green tea has been studied for its antiviral activity against Herpes Simplex Virus (HSV). Topical application was found to have an anti-herpetic effect when applied hours after the virus inoculated. We also love to supplement green tea extract orally, for high-risk HPV. Licorice Licorice has been used for many centuries for a wide variety of conditions. Today the herb is used to help with conditions like acid reflux, hot flashes, and viral infections. Licorice has also been found to have anti-inflammatory and anti-microbial properties for skin conditions. One study showed improvements in eczema with topical use of licorice root extract. The Licorice was also found to have antiviral activities against HSV-1 in vitro. Red algae Red algae are one of the oldest groups of eukaryotic algae. This mineral-rich marine plant contains a therapeutic compound called carrageenan, which has been studied for its use on HPV. Another compound in red algae called griffithsin has been found to interfere with HPV entry into cells. Together griffithsin and carrageenan have powerful antiviral activities and may help clear warts caused by HPV. Peppermint essential oil Peppermint oil is extracted from the leaves of the peppermint plant. The oil has been used as an aide in several conditions. Peppermint is a commonly used antiseptic and anti-inflammatory that can be applied topically to help alleviate pain. The oil may also help alleviate skin itching. Research evaluating the use of peppermint oil on viruses has found it to have strong antiherpetic activity against HSV-1 and HSV-2. Further studies have confirmed an inhibitory effect on HSV infections. Vitamin C Most of us are familiar with the powerful immune and antioxidant properties of vitamin C. Vitamin C is also a skin supportive vitamin, helping stimulate collagen production. Topical use of vitamin C on recurrent herpes infections was found to shorten the persistence of scabs in 2.5 days. The active compounds in vitamin C work by stimulating mucolytic and antimicrobial activities. Aloe Vera Aloe vera is commonly known for its wound-healing effects, applied topically to relieve sunburns and help heal wounds. Aloe vera’s therapeutic activity comes from its concentration of glycerin extract which forms a protective mucilage over damaged tissues. Aloe when applied topically has also been found to have antiviral activity on the herpes simplex virus. Our new topical formula combines all these and more into a plant-powered solution to genital warts. Together these ingredients can help promote skin healing and target viral activity. Interested in testing it out? We are looking for customer feedback. We will send you a free product exchange for your honest feedback and experience. Contact customerservice@wellex.co to let us know you are interested in testing our newest product.
Feb 21, 2022
4 min read
The Root Causes of HPV

The Root Causes of HPV

Adrienne Hill-Strathy
We know that the Human Papillomavirus (HPV) causes 98% of all cancers of the cervix. HPV is also linked to anal, vulva, and other cancers of the genital tract. With that said, not everyone who contracts HPV will develop complications. Most cases of HPV will spontaneously regress on their own within 2-3 years. In the small few where HPV doesn’t revert and becomes chronic, it can lead to progressive cellular changes over time which can sometimes lead to cancer. So, what makes one person more susceptible to persistent HPV infections than another? Let’s explore a few root factors that could be at play. Addressing these root causes can help support the body to clear HPV and prevent cervical and other HPV-related cancers. Nutrient Deficiencies Nutrients form the backbone and catalysts for many reactions and processes in the body. Today, many individuals are deficient in important nutrients, and these deficiencies make it difficult for the body ecosystem to function optimally. Studies have found several nutrients to be correlated with HPV infections. Persistent HPV infections are more common in individuals with low levels of folate (B9), vitamin A, vitamin C, vitamin E, and selenium. With these deficiencies, there is also an increased risk of progression to cervical cancer. HPV rates decline in individuals with higher levels of these nutrients. The underlying action of these nutrients is to help support healthy immune function through inhibiting cancer cell growth and their powerful antioxidant activities. Nutrient deficiencies can be corrected by consuming a diet rich in diverse whole foods, especially fruits and vegetables. We like to aim for 8 to 10 servings per day with at least one serving coming from green leafy vegetables.  Nutrient levels can also be corrected through supplementation. Papillex™ was formulated with this research in mind. Our nutritional supplement offers the daily recommended serving of micronutrients known to support HPV.  The Vaginal Microbiome Within our body’s ecosystem exists separate micro-ecosystems including the vaginal microbiome. The vagina is home to trillions of microorganisms – bacteria, fungi, and viruses. These organisms play a role in the health and function of the vagina. When certain species overgrow or get depleted, health complications can occur. The vaginal microbiome is largely populated by the Lactobacillus species. Studies find that HPV is more common in individuals with lower levels of Lactobacillus. In individuals with cervical dysplasia levels of unhealthy microbes like Prevotella, Sneathia, and Clostridiales are increased. Research also seems to indicate that HPV infection can disrupt the vaginal microflora, allowing the virus to persist.  Screening for vaginal infections like bacterial vaginosis, candida, and trichomonas vaginalis can help detect if there is an underlying imbalance and inform how to treat it. If you notice any changes in vaginal symptoms such as irritation, redness, pain, or changes to discharge, contact your doctor. Taking care of your vaginal health is just like taking care of your overall health - eat a nutrient-rich diet, reduce sugar intake and processed food, and fill up on those pre-biotics and probiotics. Maintain proper hygiene practices by avoiding douches and soaps, using organic, scent-free personal care products, and cotton underwear. Safe sex practices are also important to your overall wellbeing - wearing condoms can reduce exposure to other bacteria and sexually transmitted infections as well as maintain vaginal pH. Inflammation Inflammation is a natural immune response to repair tissue damage and defend the body against invaders. However, unchecked and chronic inflammation is at the root of many chronic diseases. It is helpful to think of the body as one interconnected ecosystem when considering the impact of inflammation on cervical health. When inflammation is out of balance, it can contribute to the body’s vulnerability to tissue damage. Research has found inflammation and oxidative stress to play a role in HPV persistence. The HPV virus is better able to infiltrate into the cells when the tissue is inflamed. Chronic inflammation also helps cells proliferate over time, allowing for those cervical cell changes to occur. In addition, the HPV itself is also inflammatory and its cellular process further induces inflammation at the local site. Reducing inflammation is another whole-body approach. Dietary factors play a role in supplying the body with antioxidants, known to balance inflammatory oxidative processes. Antioxidants are best obtained from eating a diverse diet of whole foods. We also recommend reducing exposure to inflammatory triggers like cigarette smoke, alcohol, and processed foods (trans fats and refined carbohydrates) as well as managing blood sugar through consuming adequate protein, fats, and complex carbohydrates to keep inflammation down. In addition to dietary changes, getting 7-8 hours of good quality sleep per night is crucial for the immune system. Genetics Certain genetic factors have also been explored for their role in HPV. Studies suggest there is a familial predisposition to cervical cancer. More specifically, research indicates that individuals whose mother or sister had HPV have an increased chance of developing cervical dysplasia and cervical cancer. This increased risk could be due to several factors. Certain genes were found to be associated with HPV risk as well as HLA alleles. A person’s genotype may also influence risk behaviors that influence HPV. Our genes may also impact our DNA repair and detoxification pathways. Associations between the MTHFR gene and cervical cancer may also exist. MTHFR plays a role in converting dietary folate into folic acid to be used in detoxification and cellular repair pathways. An MTHFR mutation increases the risk of several diseases including heart disease, colon cancer, and breast cancer. Some evidence suggests there is a link between genetic variants of MTHFR and cervical cancer, but more research is needed. Increasing dietary folate through intake of leafy green vegetables, beans, and supplementation, can help support this pathway. Hormones Hormones also play an important role as the chemical messengers that act throughout the body. Hormones were first thought to play a role in HPV infections following findings that HPV infections were more common in individuals on oral contraceptive pills and after having multiple pregnancies. The sex hormone, estrogen, is thought to explain why rates of cervical dysplasia increase in these groups. Reducing exposure to xenoestrogens, estrogens found outside the body can help reduce this risk. Consider non-hormonal methods of birth control as a way to reduce risk. Again, diet and lifestyle factors play a role in supporting healthy hormone production and function. A diet rich in cruciferous vegetables (broccoli, cabbage, and kale) can help support estrogen detoxification and clearance. Intake of phytoestrogens like flaxseed and soy can help support a healthy hormone balance. Why lifestyle is key The good thing is most of these factors are modifiable through lifestyle practices. The daily choices you make can influence your likelihood of developing cervical cancer or other HPV complications. As we have said, supporting the body against invaders like HPV is a whole systems approach. Focusing on a nutrient-rich diet, reducing stress and exposure to harmful chemicals, and targeted supplementation can help address many of the underlying root causes that lead one to develop complications of HPV.
Jan 03, 2022
5 min read
How Does Birth Control Impact HPV?

How Does Birth Control Impact HPV?

Adrienne Hill-Strathy
One question we commonly get asked is how birth control may impact HPV. Birth control is commonly used by women of reproductive age to prevent pregnancy. Today, many also use birth control to support hormonal symptoms like PMS, acne, dysmenorrhea, and heavy menstrual bleeding. Many factors are often considered when choosing a birth control that is right for you. In this article, we will explore three popular birth control methods and things to consider with regard to HPV. Let’s Start With The Oral Contraceptive Pill (OCP) The OCP is a hormone modulating birth control. The OCP contains estrogen and progesterone, two hormones involved in the reproductive cycle. Individuals who menstruate often go on the OCP to prevent pregnancy as well as control hormonal symptoms like premenstrual syndrome (PMS), acne, painful periods, and heavy menstruation. The OCP is speculated to increase HPV persistence and progression. The pill may do this by altering certain genes as well as increasing the cervical maturation process which allows cell proliferation of HPV. By taking a synthetic hormone you may change the susceptibility of the cervical cells to high-risk infections. Moreover, because the OCP contains growth-stimulating hormones estrogen and progesterone, there is some risk that they can increase the risk of cervical cancer. Studies have found that long-term use (10 years or longer) of oral contraceptives has a four-fold increased risk of developing cervical cancer. A study of over 46,000 individuals found that those who are used OCP had a significantly higher rate of cervical cancer and abnormal cervical cell growth than non-users. The research does also suggests that the risk decreases after stopping the pill. HPV rates decline with time since quitting. The OCP may also lead to nutrient deficiencies associated with HPV.  The pill can deplete riboflavin, vitamin B6, folic acid, vitamin C, and zinc. We know these nutrients are important players in supporting the immune system and some have even been specifically linked to HPV. Moreover, the birth control pill is also known to alter the gut microbiome. The pill may increase leaky gut, dysbiosis, and candida overgrowth. A healthy gut is another foundation for our immune and overall health. Impairing this system can have a widespread impact on the rest of the body. Considering these impacts, it is important to support nutrient levels and gut health if taking the OCP. We recommend optimizing dietary intake of diverse fruits and vegetables, fibers, and probiotic foods as well as considering supplementation. Condoms Condoms are a favorable form of birth control when it comes to protecting against Sexually Transmitted Infections (STIs) and pregnancy. Condoms form a barrier between mucosal contacts and are found to be 98 percent effective at protecting against STIs like chlamydia and gonorrhea. However, because skin-to-skin contact can still occur with condom use, they are less effective at preventing the spread of herpes, genital warts, and HPV. That’s right. Unfortunately, HPV can still be transmitted through condom use. Nevertheless, condom use is still warranted and recommended. Some studies have found that the risk for genital warts and the grade of cervical intraepithelial neoplasia (CIN) was reduced in condom users. Condoms also protect against other STIs and infections that can contribute to co-infections and impair the vaginal microbiome. IUD The intrauterine device comes in both a hormonal and non-hormonal form. Both are inserted into the uterus for long-term, effective pregnancy prevention. The hormonal IUD delivers a small amount of progestin to the local uterine tissue. Some individuals notice side effects like changes in mood, bloating, cramping, or reduced menstruation. The IUD can also get displaced and in rare cases perforate the uterus. The hormonal release of the IUD is lower than the OCP. The IUD releases one hormone, progestin, at a dose of fewer than 20 micrograms each day. Whereas the OCP releases 1 milligram of progestin and 0.02 to 0.06 milligrams of estrogen each day. The non-hormonal option is a copper IUD that prevents pregnancy by releasing copper in the uterus that is toxic to sperm. The copper IUD will not suppress ovulation and the most common side effect is heavier menstrual bleeding. While the copper IUD has no hormonal impact, the heavier menstrual bleeding can contribute to iron deficiencies and anemia. What’s The IUD Connection with HPV? Some studies have shown that sexually active individuals with the IUD group had higher clearance rates of HPV. While others, when adjusted for other variables, found no association between IUD use and HPV infection or persistence. Research comparing the difference between the copper IUD and hormonal has found mixed results. One study found the hormonal IUD to have a lower risk of high-risk HPV than the copper IUD. Another study found the copper IUD to have a lower risk of cervical neoplasm. Overall, it is unclear how these devices are influencing cervical dysplasia and HPV infections or the mechanism of action. It is also important to note that the IUD and OCP do also not protect against other STI’s like chlamydia and gonorrhea, while condoms do. So how can you decrease your risk of HPV? You are probably thinking, what then can I use to protect myself against HPV and STI’s? Currently, condoms and engaging with fewer sexual partners are the best ways to reduce your risk of exposure to HPV. However, we understand that other factors are involved. We always recommend talking to your health practitioner to help decide what is best for you. Because most sexually active individuals carry some form of HPV and it can be transmitted through skin contact, no form of birth control can completely protect you. More importantly, you can support your whole-body system so that if you are infected, you are better equipped to defend against pathogens and viruses.
Dec 13, 2021
4 min read
Inflammation and HPV

Inflammation and HPV

Adrienne Hill-Strathy
Inflammation is the body’s natural response to injury and infection. Without the natural inflammatory response, we would not fair very well! When inflammation occurs, immune molecules are recruited to the site of injury or invasion to release other immune cells (cytokines, hormones, and white blood cells). These immune cells help repair and restore the body to optimal, healthy function. However, inflammation can also cause harm. If the inflammatory response is stimulated too much and for too long, chronic inflammation occurs. During prolonged inflammation, the balance between oxidants and antioxidants is thrown off causing oxidative stress. Oxidative stress promotes the release of more inflammatory molecules. These reactive oxygen molecules damage proteins, cells, and DNA, which increases the risk of diseases and cancers. This inflammatory response is thought to contribute to the progression of HPV infections to cervical cancers. Inflammation and cervical health We know that the immune system is a key factor in regressing HPV infections. Studies have found inflammatory molecules assist the virus to integrate and proliferate into an individual’s tissues. This means that the more inflammation present, the easier it is for viruses to infect our tissues. Inflammation leaves our cells more vulnerable to further damage. HPV itself also drives inflammation. The viral particles produced by the HPV (E6, and E7) are also inflammatory and drive more inflammation which further decreases the level of antioxidants, our main weapons against oxidative damage. Together these processes allow HPV to persist. What increases inflammation? Chronic inflammation is caused by multiple factors. Some factors we have little control over like infections and injury. Other factors are lifestyle-based like diet, nutrient levels, environmental toxins, stress, and lack of sleep. Fortunately, we do have some control over these factors. How to tame the flame Eliminate inflammatory triggers Reducing exposure to known inflammatory triggers like smoking and alcohol is number one in lowering our overall load. Processed foods, refined sugar, and hydrogenated oils can also be pro-inflammatory. We also know smoking increases the risk of HPV and cervical cancer. Fuel up on antioxidants Antioxidants are some of our best sources of inflammation-fighting molecules. Obtaining antioxidants is best done through the diet. With 80 percent of the immune system located in the gut, so what we put into our bodies in the form of food directly interacts with the immune system. Plant-based whole foods offer our greatest source of antioxidants. Aim for 8-10 servings of colorful fruits and vegetables each day. Rotate your veggies often to optimize the unique nutrients and antioxidants in different plant foods. Supplementation can also play a role in supplying antioxidants. By consuming a greater ratio of antioxidants, we can reduce chronic inflammation. Studies find intake of antioxidants like vitamin A, vitamin E, and vitamin C can neutralize free radicals and are associated with a preventative effect on cervical cancer. The star players Some antioxidants have potent disease-fighting properties than others. Our favorites include Glutathione Glutathione is best known for its powerful antioxidant activities. The compound is composed of three naturally occurring amino acids, cysteine, glutamic acid, and glycine. Glutathione can help repair cellular damage caused by oxidative stress and supports the liver in detoxifying hormones and toxins. Studies have found glutathione levels to be low in individuals with cervical cell changes. We can support the body’s natural production of glutathione through supplementing NAC, a natural form of cysteine. Vitamin C, methyl folate, selenium, and curcumin also support glutathione production. Green tea extract Green tea contains powerful polyphenols, called EGCG, that have been found to play a role in regressing HPV infections. The antioxidants in EGCG inhibit the cell changes that occur in cervical cancer. Several studies have found supplementing green tea extract has anti-viral and anti-infective effect that stimulates the immune system. The compound can also be used topically to clear genital warts. To obtain the therapeutic amount of green tea extract, drinking a cup of green tea isn’t enough. Supplementing offers a much stronger dose. We recommend taking 300-600 mg a day. Indole-3-Carbinol (I3C) and diindolylmethane (DIM) I3C and DIM are superfood antioxidants found in the broccoli family. 3C and DIM are produced in the stomach after consuming cruciferous vegetables. The compounds have been found to help naturally support and repair DNA damage and reduce the risk of cancer. One study evaluated oral DIM treatment in individuals with CIN 2 or 3 cervical lesions scheduled for LEEP procedure. Those in the treatment group took 2 mg/kg/day of DIM for 12 weeks. The placebo took a rice bran pill for 12 weeks. At the 6 months follow-up of the study, 84% of the treatment group had improved findings on colposcopy and 85% didn’t require a LEEP. However, no statistical significance was found between the treatment and placebo. While it is unclear if DIM treatment alone can clear HPV, its powerful antioxidant capabilities in combination with other nutrients and support can contribute to our overall HPV defense.  Medicinal mushrooms Medicinal mushrooms are another natural compound that has been used for centuries to support the immune system and inflammatory processes. Mushrooms contain active compounds called polysaccharides. These compounds can inhibit chronically elevated inflammatory molecules like IL-6, prostaglandins, and leukotrienes. Glucans are a type of polysaccharide that stimulates the production of immune molecules like natural killer cells and cytokines. These cells help the immune system clear away unwanted invaders. Reishi mushroom is commonly used for immune support. It has been found to have anti-inflammatory properties in melanoma and breast cancers. Active Hexose Correlated Compound or AHCC is another mushroom extract that contains a high level of alpha and beta-glucans that modulate the immune system. AHCC has been found to support immune support in cancers and viral infections.
Nov 29, 2021
4 min read
How the Vaginal Microbiome may be Contributing to your HPV

How the Vaginal Microbiome may be Contributing to your HPV

Adrienne Hill-Strathy
Our bodies are inhabited by millions of tiny living microbes. You may already be familiar with the living organisms in the gut. Our genitals each have an ecosystem of microbes as well. The bacterial composition of our vaginal microbiome plays a role in our overall health, including simmering infections like HPV. Vaginal microbial diversity and richness is a key player in the immune system. Healthy microbes help prevent many urogenital diseases, yeast infections, and other Sexually Transmitted Infections. Breaking down the microbes The key player in the vaginal microbiome is a bacteria called Lactobacillus. This lactic-acid-producing organism is thought to be the main defense against incoming invaders in the vagina. Lactobacillus helps maintain a low vaginal pH and protects the vaginal mucosal lining. The abundance of Lactobacillus species is lower in individuals infected with HPV. Moreover, individuals with cervical dysplasia show higher proportions of unhealthy microorganisms like Prevotella, Sneathia, and Clostridiales. The chicken or the egg? It seems HPV infections may impact normal microflora. Likewise, an unhealthy flora can also allow for HPV to persist. As the virus initiates healthy cervical cell immune defenses, it can disrupt the vaginal microbiome and promote HPV persistence and progression. As we continue to learn more about the microbial connection to STIs, it is important to consider how the vaginal microbiome may be contributing to your HPV infection and what you can do to fix it. Types of vaginal infections: There are three main types of vaginal infections.  Bacterial vaginosis (BV) is the most common type of vaginal infection in adult women. Around 30 percent of women between the ages of 20 and 50 have BV. BV is characterized by an overgrowth of certain bacteria and an elevated vaginal pH. It often presents with symptoms of a fishy odor, greyish discharge, itching, and irritation. Studies have found a positive correlation between BV infections and HPV. The connection is thought to be due to reductions in Lactobacillus (the beneficial microbes) and an increase in sialidases (the pathogenic ones). The loss of beneficial bacteria reduces the protective microorganisms and changes in the vaginal microflora, which may promote the survival and development of HPV. The increase in the presence of sialidases can cause microdamage to the epithelial cells and increase the susceptibility to cervical HPV infections. Trichomonas vaginalis (TV) is another common STI. It can also cause a foul odor, genital redness or burning, and pain with urination and intercourse. A positive association was also found between TV infections and positive HPV infections. Vulvovaginal candidiasis, also known as a yeast infection, is another common vaginal infection. Candida results from an overgrowth of fungal species in the vaginal canal. Research has found that candida infections were not associated with an increased risk of HPV infections. This is likely because candida does not impair the lactobacillus-predominated vaginal microbiota. How do I know if I have a vaginal infection? Vaginal infections often present with signs and symptoms. You may notice: Vaginal irritation Changes in color, odor (often fishy), and/or consistency of discharge Redness Pain or tenderness Itching Burning or pain on urination If you notice changes in vaginal symptoms, contact your doctor. A vaginal exam and swab can be done to determine the cause. Tips to take care of your vaginal health Lifestyle choices can play an important role in supporting the vaginal microbiome. Optimal vaginal health depends on the health of the whole body. Treatment is focused on supporting both the local environment, as well as the wider body system. organic basil herbs on display at the farmer's market. Diet: Because the body is one interconnected system, what you eat can influence the vaginal microbiome. A diet low in sugar and refined carbohydrates can support a healthy microflora. Sugars are found in cakes, cookies, pastries, and alcohol should be limited to special occasions. Sugars from fruits and other natural sources like honey and maple syrup should be enjoyed but not overdone. By reducing sugar intake, blood sugar is better managed allowing for healthy hormone regulation. Consuming a diet rich in a diversity of fruits and vegetables can also help support a healthy microbiome and supply micronutrients to enhance overall health. Probiotics: oral and vaginal probiotics can help support the vaginal microflora. It is important to opt for a high-quality probiotic. Probiotics that contain Lactobacillus reuteri, Lactobacillus rhamnosus, and Lactobacillus crispatus are known to support vaginal microflora. For vaginal suppositories, probiotics are often recommended for 10 days through insertion into the vaginal canal each night before bed.   Hygiene: The vagina is self-cleaning. Maintaining proper vaginal hygiene by simply washing with warm water and avoiding douches and soaps is also helpful. Because the tissue in the vagina is some of the most absorptive tissue in the body, toxins, and chemicals in tampons can be easily absorbed and disrupt the microbiome and cause inflammation. We recommend opting for organic, scent-free products to reduce disruption. Sexual activity: Sexual intercourse and semen can also change the vaginal microflora and alter the vaginal pH. New partners can initiate the vaginal immune defenses and cause inflammation. Wearing condoms has been found to reduce occurrences of BV and other Sexually Transmitted Infections.
Nov 01, 2021
4 min read
How Do Your Hormones Influence HPV?

How Do Your Hormones Influence HPV?

Adrienne Hill-Strathy
Hormones play an important role in the body’s chemical messaging system. Hormones help direct and regulate many bodily processes. Like most systems, hormones operate within a delicate balance that can lead to undesirable symptoms and disease when disturbed. We have talked a lot about the importance of lifestyle and dietary factors as well as genetics and nutrient levels in the progression of HPV. But how do hormones fit into all of this? Here is what we know. Hormones and HPV The role of hormones in the development of HPV first started to be explored following findings that HPV infections were more common in individuals on oral contraceptive pills (OCPs) and women with multiple pregnancies. There is a two to four-fold increase in HPV persistence in individuals on the OCP than non-OCP users. The risk increases the longer the individual is on birth control and declines once they go off it. The mechanism that might explain this is the increase in synthetic estrogen delivered through the OCP, leading to an increase in estrogen in the blood. In individuals with seven or more pregnancies, cervical cancer risk increases 3.8-fold as well. Like the OCP, pregnant women are exposed to elevated estrogen levels, which may explain the correlation. To further understand the estrogen-HPV link, mouse studies have been conducted. In one study mice were injected with estrogen for 6 months or 9 months. All mice in the study developed cervical tumors. However, the mice that were given estrogen for longer (9 months, instead of 6 months) showed a significant increase in the number of tumors and their size. Moreover, the mice treated for less time saw a reduction in tumors compared to those treated for 9 months. This suggests that the longer the exposure to estrogen, the higher incidence of cervical tumor number and size. The study also helped shed light on the part of cancer development impacted by estrogen. Because tumor growth was seen in all mice, estrogen appeared to initiate tumor development. Additionally, the increased growth in the 9-month group also supports estrogen’s role in cancer progression. It is important to note that this study was done in mice models and therefore may not be replicable in humans. Nevertheless, these findings may warrant more caution used with OCPs in HPV-infected individuals and increased screening in women with more pregnancies. A Bit About The Hormone Estrogen Estrogen is a sex hormone. Both males and females carry this hormone, but it plays a larger role in the development of the female reproductive tract. Estrogen is typically released cyclically during the menstrual cycle to stimulate the growth of the egg follicle and the endometrium lining to prepare the uterus for a possible pregnancy. Estrogen also contributes to many other bodily processes like cognitive health and the cardiovascular system. Estrogen levels fluctuate among different individuals and can vary over the month and lifetime. The fluctuations can alter growth processes in the body, influence mood, and create symptoms like hot flashes during menopause. While estrogen generally supports bodily processes, the hormone is carcinogenic in certain doses and can contribute to the formation and growth of tumors. Excess or lost estrogen can also lead to disruptions in the menstrual cycle and increase symptoms of premenstrual syndrome. Other Estrogen Exposures In addition to OCPs and pregnancy, estrogen levels may be increased through other external sources or xenoestrogens. Many foods, environmental contaminants, and personal care products have been found to contain hormone modulating chemicals that mimic estrogen in the body. Accumulated exposure to these compounds may disrupt normal hormone levels and contribute to estrogen-related cancers. Research has found an increased risk of gender-related cancers and xenoestrogen exposure. However, we currently do not have a good understanding of the cumulative impact of these hormone disruptive chemicals on cervical cancer. How to support healthy estrogen levels Avoid the OCP: Given the strong association between OCP and HPV, alternative birth control options may be preferred to reduce the risk of HPV. Buy organic foods: pesticides, chemicals, hormones, and antibiotics added to some foods can alter natural hormone levels in humans. Focus on antibiotic-free and organic produce and meats as much as possible to limit exposure to harmful estrogens. Eat your fruits and vegetables: eating a diversity of plant foods supplies the body with the micronutrients and antioxidants to support healthy detoxification. The liver and gastrointestinal system are primarily responsible for metabolizing and eliminating estrogen to keep them in a healthy balance. Green leafy vegetables and cruciferous vegetables (Brussel sprouts, kale, cauliflower, cabbage) are especially helpful in supporting liver metabolism. Aim for 7-10 servings of plants a day. Consume flaxseeds: flax is a phytoestrogen, a form of estrogen we get from foods. Phytoestrogens have been found to support healthy hormone levels. Aim for 1-2 tbsp of ground flaxseed per day.
Oct 04, 2021
4 min read
Letting Go: The Shame of HPV

Letting Go: The Shame of HPV

Adrienne Hill-Strathy
Shame is the intensely painful feeling or experience of believing that we are flawed, and therefore unworthy of love and belonging (Brene Brown, 2012). We all have known and have experienced the discomforting wash of shame at some point in our lives. Under our shame often lies our rooted beliefs and experiences that tell us we are bad. Shame differs from guilt in that our guilt tells us we did something bad, our shame tells us that we are bad. Shame is intense and can lead to secrecy, silence, and judgment. STI’s and Shame From a young age, we have been taught to fear sexually transmitted infections (STIs). Sexual health education, media, and society have all painted the picture that STIs are dirty and disgusting - by that logic, if we catch one, we must be dirty and disgusting, too.  Because HPV is an STI, we often feel ashamed of our diagnosis.  Holding onto shame can prevent us from living a healthy life, and can contribute to stress and unhealthy behaviors that impair our immune system. Letting go of the shame associated with HPV may be foundational to our healing. In this article, we share a few ways you can reframe your narrative to understand that HPV isn’t something to be ashamed about. By releasing our shame, we make space to empower ourselves and others. How to Let go of Shame To let go of the shame of HPV, it is important to clarify a few things about the virus, how it is contracted, and how prevalent it is - with this information, we can begin to change our narrative. Creating a new narrative: the truth about HPV HPV is a virus.  As humans, we are naturally exposed to viruses and other pathogens that live in our environment - this is a part of life. Strains of the HPV family have an affinity for skin tissue in and around the genital or mouth areas. The virus is passed on through skin-to-skin contact with an infected individual. HPV is so common that an estimated 80 percent of women will contract a strain of HPV in their lifetime.  Once infected, the virus makes a home within the human tissue cells. In most cases, the immune system will identify and suppress the virus activity over time leading to no symptoms or complications. In some cases, the virus may proliferate and slowly cause cellular dysplasia that can lead to cervical cancer over many years. Given the large number of HPV strains and high transmission rate of the virus, the best way to avoid exposure includes abstaining from sexual activities or limiting your number of sexual partners. Sexual activity is a significant part of the human experience.  Asking you to suppress your sexuality would be like asking you to stay in your house for the rest of your life to avoid catching a cold. We can aim to prevent infection by avoiding risk factors, but we don’t want to miss out on life! Instead of staying at home, our body has an innate system called the immune system, which we rely on to support and protect us from infection and disease. We can take preventative action by making sure this system is up and running efficiently to protect us against viruses. Now that we understand a little more about the virus, it is time to foster a little empathy. Fostering empathy for yourself: If the root of our shame lies in our feelings of being unworthy of love and belonging, letting go of shame requires a healthy dose of empathy. Empathy involves showing compassion and kindness to ourselves, which can feel unnatural and uncomfortable at first. Imagine talking to yourself like you would talk to a young child or a close friend. How would you speak to them in a similar situation? I would imagine it is different from how you talk to yourself, because we are often harshest to ourselves. Remind yourself that you are not to blame, you are not unworthy, and you are deserving of care. Self-compassion and empathy is a continuous practice.  Name it to tame it One of the most powerful tools we can use to reduce our shame is to talk about it. When we can name our shame, we tame our shame.  So many women suffer the HPV diagnosis in silence but find that when they do speak up they can connect with so many others who are experiencing the same thing. Speaking up about our shame is a vulnerable and emotional risk. With that risk lies the power of vulnerability - it creates space for others to feel less afraid, less alone, and less ashamed. When we don’t talk about these things, we can unintentionally breed shame. Try opening up to someone you trust. Turn to a trusted friend, family member, or counselor - someone who can hold space for you and just listen. We know that talking to a partner can be scary and intimidating, but have found that many who have opened up about their sexual health with their partners often find it brings them closer. Speaking your truth also allows for a chance to practice being your most honest and authentic self. Shame has a powerful weight on each of us, and we all experience it at some point. Often, the shame associated with HPV is rooted in our misunderstanding of the virus and the narrative we have created around contracting sexually transmitted infections.  Remember that shame also does not help you and it does not help others. Be kind to yourself and show yourself compassion - your vulnerability can give others the courage and strength to let go of shame as well. Sources: https://www.ted.com/talks/brene_brown_listening_to_shame?language=en
Jul 26, 2021
4 min read
AHCC® and Genital Warts

AHCC® and Genital Warts

Adrienne Hill-Strathy
Genital Warts are one symptom of the Human Papillomavirus (HPV). Warts are caused by specific strains of the HPV family. These strains cause soft, fleshy, and often irritating growths around the genital areas. If you have developed genital warts, you are probably wondering, “how do I get rid of them?” and “what does this mean for my health?” In this blog, we break down all things genital warts, as well as provide information about a new medicinal mushroom compound called AHCC®. AHCC® has been found to support the immune system and eradicate viral infections like HPV.  What are Genital Warts? Genital warts usually appear on the vulva, vagina, scrotum, or penis a few weeks to two to three months after exposure to an HPV infection. The warts tend to be soft, fleshy, skin-colored, or appear as white bumps. They may grow in singles or multiples, sometimes appearing as a cauliflower-like growth. While genital warts can be itchy, annoying, and persistent, they are harmless. How Did I Contract Genital Warts? The HPV family includes over 100 different viruses that commonly infect humans. The virus is so common because it is easily transmitted through skin-to-skin contact.  Genital warts can be transmitted through sexual interaction with the vagina, anus, oral sex, or hand contact. Transmission can even occur through individuals without visible warts or symptoms. Given the ease of transmission, it is estimated that 80 percent of people will be exposed to an HPV infection at some point in their lifetime. The risk of developing complications depends on the viral strain of HPV that you have contracted.  What are the complications of contracting genital warts? Fortunately, the strains of HPV that cause genital warts do not cause cancer. The strains of HPV associated with warts are considered low-risk. HPV tends to arise two to three months after infection and can last anywhere from a few weeks to a few years. High-risk strains that are often asymptomatic can eventually progress into cancer. It is important to note that contracting one strain of HPV does not make you immune to contracting other strains of HPV. Even if you have low-risk HPV, you can still be exposed to high-risk strains and should follow your physicians’ recommendations and receive regular testing. You can also pass the infection on to another person even once the warts have gone away. Can genital warts be treated? If you have recently noticed an outbreak of genital warts - what can you do to get rid of them? HPV and genital warts can be treated. Viruses and other pathogens that affect humans are suppressed by the immune system. Immune molecules such as natural killer cells, cytokines, and macrophages play a role in identifying and eliminating these foreign invaders. One way to naturally enhance the function and production of the immune system is through medicinal mushrooms. AHCC® and genital warts Active hexose correlated compound, or AHCC®, is a medicinal mushroom extract with immune-modulating and antioxidant activities. AHCC® has been researched for its use in supporting immune function in cancer treatment, viral infections, and enhancing immune function. Studies have found AHCC® to increase the natural killer cell and cytokine production, allowing for greater activation of the immune system. AHCC® also enhances T-cell and macrophage production, helping eradicate and eliminate invaders. AHCC® has been clinically researched as immune support for people suffering from persistent high-risk HPV infections. Dr. Judith A. Smith, of the University of Texas, has led two clinical trials of the use of AHCC® in people with HPV. The studies have evaluated a dose of 1 and 3 grams of AHCC® daily in high-risk HPV-infected individuals. The results of both studies have found AHCC® to have statistical significance in eradicating HPV infections compared to placebo.   No research studies have specifically evaluated AHCC® on genital warts. However, the underlying immune system support is important for clearing viral infections because it is the first to respond to and identify threats to the body for elimination.  What else can I do? There are certain lifestyle changes you can make to reduce your risk of infection: Quit Smoking and reduce alcohol: Smoking cigarettes impacts nearly every tissue in the body. No safe limit is recommended for use.  Reduce alcohol intake: Drinking alcohol can suppress the immune system. If you choose to drink, aim for less than 2-3 glasses per week.  Long-term use of oral contraceptives: Oral contraceptives have been linked to an increased risk of cervical cancer. Amp up your diet: Eating a nutrient-dense diet full of fruits and vegetables. Individuals who consumed more vegetables are less likely to have HPV.  Green tea extract: Green tea extract has also been shown to inhibit the development of HPV warts and cervical lesions.
Jun 28, 2021
4 min read

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