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Topical Herbs for HPV and Genital Warts
Adrienne Hill-Strathy
Genital warts are a common symptom of low-risk strains of the Human Papillomavirus (HPV). Genital warts are typically harmless, however, they can cause discomfort, irritation, and distress.
A lot of people are interested in natural herbs and nutrients to support their bodies against low-risk strains and warts from HPV. Herbal therapies offer attractive treatments for HPV given their strong safety profile and wide therapeutic index. Here we share some of the best ingredients and evidence to support the use of topical herbal therapies on viral infections.
It should be noted that many of the studies included in the review do not specifically review HPV but other viral infections like the Herpes Simplex Virus (HSV) and influenza. The antiviral actions work similarly on the HPV, but more research is needed on topical herbal products to fully understand their use.
The Ingredients
Turkey tail
Turkey tail is a medicinal mushroom know to have immune-modulating and energizing effects. The mushroom grows in a multicolored array on fallen trees in wooded areas of North America. The compound has been taken orally for centuries to treat respiratory conditions and has been used as an adjunctive in cancer treatment.
The mushroom was found to have antiviral activities against influenza and HSV viruses in cell studies. The active compounds in turkey tail include polysaccharides called PSP and PSK. These compounds appear to act on the immune system and can inhibit the growth of cancer cells. Most people tolerate turkey tail well. The compound is considered safe, though it may cause mild gastrointestinal side effects like heartburn, constipation, and nausea when taken orally.
Lemon balm
Also known as Melissa officinalis, this herb comes from the mint family and has a lemon scent to it. Commonly used to improve mood, calm anxiety, and improve cognitive function, lemon balm also has antiherpetic and antiviral effects on the HSV family.
Studies have found topical application of lemon balm to provide therapeutic action against recurrent herpes infections and cold sores. In one study, participants applied either lemon balm or a placebo to affected areas four times a day for five days. At the end of the five days, the participants that used the lemon balm had fewer symptoms of itching, burning, and redness. The lemon balm group also had faster healing than the placebo group.
Echinacea root
Echinacea is a commonly used herb for treating colds, flu, and other viral infections. The plant has anti-inflammatory, immunomodulatory, and antioxidant properties that have been used for centuries to treat various ailments.
Studies find echinacea to benefit the immune system to combat viruses. Specifically, echinacea has been found to have antiviral activities against the HSV. Topically, echinacea has been found to help improve skin hydration, reduce acne and improve eczema symptoms and skin repair.
Green tea extract
Commonly known for its energy-boosting properties, green tea also has powerful antioxidant activity that protects against free radical damage.
Green tea has been studied for its antiviral activity against Herpes Simplex Virus (HSV). Topical application was found to have an anti-herpetic effect when applied hours after the virus inoculated. We also love to supplement green tea extract orally, for high-risk HPV.
Licorice
Licorice has been used for many centuries for a wide variety of conditions. Today the herb is used to help with conditions like acid reflux, hot flashes, and viral infections.
Licorice has also been found to have anti-inflammatory and anti-microbial properties for skin conditions. One study showed improvements in eczema with topical use of licorice root extract. The Licorice was also found to have antiviral activities against HSV-1 in vitro.
Red algae
Red algae are one of the oldest groups of eukaryotic algae. This mineral-rich marine plant contains a therapeutic compound called carrageenan, which has been studied for its use on HPV. Another compound in red algae called griffithsin has been found to interfere with HPV entry into cells. Together griffithsin and carrageenan have powerful antiviral activities and may help clear warts caused by HPV.
Peppermint essential oil
Peppermint oil is extracted from the leaves of the peppermint plant. The oil has been used as an aide in several conditions. Peppermint is a commonly used antiseptic and anti-inflammatory that can be applied topically to help alleviate pain.
The oil may also help alleviate skin itching. Research evaluating the use of peppermint oil on viruses has found it to have strong antiherpetic activity against HSV-1 and HSV-2. Further studies have confirmed an inhibitory effect on HSV infections.
Vitamin C
Most of us are familiar with the powerful immune and antioxidant properties of vitamin C. Vitamin C is also a skin supportive vitamin, helping stimulate collagen production. Topical use of vitamin C on recurrent herpes infections was found to shorten the persistence of scabs in 2.5 days. The active compounds in vitamin C work by stimulating mucolytic and antimicrobial activities.
Aloe Vera
Aloe vera is commonly known for its wound-healing effects, applied topically to relieve sunburns and help heal wounds. Aloe vera’s therapeutic activity comes from its concentration of glycerin extract which forms a protective mucilage over damaged tissues. Aloe when applied topically has also been found to have antiviral activity on the herpes simplex virus.
Our new topical formula combines all these and more into a plant-powered solution to genital warts. Together these ingredients can help promote skin healing and target viral activity.
Interested in testing it out?
We are looking for customer feedback. We will send you a free product exchange for your honest feedback and experience. Contact customerservice@wellex.co to let us know you are interested in testing our newest product.
Feb 21, 2022
4 min read
Lifestyle Tips to Heal and Suppress HPV
Adrienne Hill-Strathy
Healing HPV involves a mind-body connection. Health requires us to address all areas of our physical, mental, and energetic wellbeing.
HPV can be a tricky infection in that it never completely goes away once the virus makes a home inside our cells. The immune system then plays a role in monitoring the infection and suppressing its activity. In a healthy response, HPV will become inactive and the virus will reside in a dormant state within the skin cells.
Unfortunately, HPV can be reactivated. If the immune system is compromised, the infection can resurface and proliferate again. It is important to establish and maintain healthy lifestyle practices to support the immune system, promote overall health, and keep the virus in an inactive state.
Here, we outline a few daily practices that can help manage daily stressors.
Managing stress
Create a grounding routine
We know stress can significantly impair the immune system and make us more susceptible to viral infections and flu. Regardless of how much we try to limit daily stressors, we will always experience challenges and fluctuating emotions. It is important to incorporate daily practices that help to calm the nervous system, process what you are experiencing, and check in to assess your needs.
Morning grounding techniques offer a place to connect with yourself and start the day feeling calm and in control. Mornings will look different for each of us, so explore and find what works best for you. You may consider starting the day with a short meditation, stretch, breathwork, journaling or read some inspiring passages from a book. It can also be helpful to write down some daily intentions or three things you are grateful for in your life. Find something that you enjoy and can stick to.
Meditation
Meditation has been used for thousands of years to manage stress and heal physical ailments. The benefits of meditation include reduced inflammation and improved gut health. Meditation activates our parasympathetic nervous system which is involved in the rest and digest response. Meditation can improve the absorption of nutrients, promote better sleep, and help manage mental health disorders[1]. To begin a meditation practice, it can be helpful to use a guided program or app. We love calm (www.calm.com) and insight timer (insighttimer.com).
To meditate on your own:
Set a timer for 5-20 minutes.
Find a comfortable seated position in a quiet and calm environment.
Close your eyes.
Focus on your breath. Count each inhale and exhale up to 10.
Thoughts will continue to arise throughout the practice, take a moment to notice them, allow them to pass, and then come back to focus on your breath.
Try doing a “body scan”. Turn your focus to each part of your body, working your way from the top of your head, down your abdomen, into your toes. Notice any sensations, textures, tension, or energies as you go.
As you finish the practice, take note of how you feel.
Breathwork
The breath helps to ground you to the present moment. Breathwork practices can be used as a simple way to relax the mind and activate the parasympathetic nervous system. Breathwork it can be done in any situation or environment without disturbance because we always have our breath with us. Repeat the following breathing exercise at least 4 times or until you feel your body relax. This practice is helpful in times of acute stress, for example, before a stressful presentation. A simple breathwork routine includes: (box diagram)
Inhale 4 counts
Hold
Exhale 8 counts
Hold
Other stress reduction tips
Spend time in nature.
Phone a friend.
Talk to a therapist or counselor.
Limit your phone and media usage.
Reduce your caffeine intake.
Journal.
Create mantras.
Get enough sleep.
Adopting a healthy diet
We know that diet plays an essential role in supporting our overall health and preventing disease. Most of us also live busy, hectic lives. This means there isn’t always time to prepare the perfect healthy salad or homecooked meal. Planning ready-to-go healthy meals can be the make or break it between grabbing a sugary candy bar or a nutritious homemade bowl for lunch.
Some tips to make mealtime easier and healthier:
Make a plan. As simple as it sounds, planning can go a long way when it comes to meal prep. Having a sense of your week, when you will be busy, and what foods will nourish you can make the process a lot easier. Take 10-15 minutes each week to plan what dishes you are going to make for the week. Pinterest, Instagram, cookbooks, blogs, etc. offer endless recipe ideas. We love to keep a recipe index, saving healthy recipes we plan to make so when your inspiration runs low you have something to turn to.
Set aside time each week to cook and prepare food. Cooking doesn’t need to be a daily task when we plan and organize our time. We recommend setting aside at least two times a week to meal prep to keep food fresh and add variety.
Make double the portions. Meal prepping a large batch can help reduce time in the kitchen later. When you cook a meal, try to make a little extra. This way you will have leftovers that can be eaten for lunch or another dinner. If you have a lot leftover, freeze some extra so that later you will have an easy meal ready to be thawed and cooked. For example, buy double the serving of chicken breasts, marinate them with some lemon juice, oil, and spices. Cook one batch and place the other in the freezer. In the morning before starting the day, take the chicken out of the freezer. It’s then easy to pop in the oven to roast later in the day!
Cut up veggies and put them center stage in your fridge. Next time you open the fridge for a little snack, they are right there and easy to grab. You will surely find yourself snacking on some healthy veggies.
Add an extra handful of greens. Another healthy tip we love is to add a handful of green into your dishes. Whether it’s a smoothie or warm bowl of soup, try adding a handful of spinach, kale, or cilantro to your meal. Not only will it amp up the taste, but it’ll amp up your micronutrient levels as well.
Nuts, grains and berries
Getting better sleep
Sleep is crucial to our health and immune system. As our body has time to rest and renew, the immune system gets activated. The body uses sleep to enhance the formation of immune molecules that defend against bacteria and viruses and builds a stronger immune system for the future. During sleep we also release a hormone called melatonin, which acts as a free radical scavenger, repairing damaged cells[2].
The recommended amount of sleep
According to the National Sleep Foundation, adults need around 7 to 9 hours of quality sleep per night[3].
Tips to get better sleep:
Take time to wind down: It is important to take time to wind down in the evening, perhaps with a nice warm Epsom salt bath and unplugging from technology. Giving yourself enough time to read a book in bed as your body starts to drift off into sleep.
Implement a bedtime routine: Going to bed and waking up at roughly the same time every day is the most effective way to regulate your circadian rhythm. Ideally, going to bed around 10-11 P.M. once the sun has set and rising around 6 or 7 A.M. when the sun is rising helps regulate our circadian rhythm and naturally induces sleep.
Avoid stimulants and alcohol: Limit caffeine intake in the afternoon and avoid alcohol intake to avoid disrupting REM sleep. Opt for herbal teas like chamomile, passionflower, or lemon balm to promote relaxation.
Keep your environment dark and cool: Our body temperature drops when we fall asleep. Sleeping in a cooler room of 67 to 68 degrees F (20 C) can trick your body into sleep mode by creating conditions that mimic the body’s natural sleep cycle.
Adopting healthy lifestyle practices doesn’t have to be complicated. Remember that it is the little things that you do consistently that add up to bigger changes. It’s also helpful to keep in mind that change doesn’t happen overnight, so stick with it and have patience. If you struggle, try scaling the changes back a little bit before challenging yourself again. Slowly you will notice healthy becomes a habit.
[1] Black, D. S., O’Reilly, G. A., Olmstead, R., Breen, E. C., & Irwin, M. R. (2015). Mindfulness Meditation and Improvement in Sleep Quality and Daytime Impairment Among Older Adults With Sleep Disturbances. JAMA Internal Medicine, 175(4), 494. https://doi.org/10.1001/jamainternmed.2014.8081
[2] Srinivasan, V., Maestroni, G. J. M., Cardinali, D. P., Esquifino, A. I., Perumal, S. R. P., & Miller, S. C. (2005). Melatonin, immune function and aging. Immunity & Ageing, 2(1), 17. https://doi.org/10.1186/1742-4933-2-17
[3] https://www.sleepfoundation.org/excessive-sleepiness/support/how-much-sleep-do-babies-and-kids-need
Jan 17, 2022
7 min read
Adrienne Hill-Strathy
We know that the Human Papillomavirus (HPV) causes 98% of all cancers of the cervix. HPV is also linked to anal, vulva, and other cancers of the genital tract. With that said, not everyone who contracts HPV will develop complications.
Most cases of HPV will spontaneously regress on their own within 2-3 years. In the small few where HPV doesn’t revert and becomes chronic, it can lead to progressive cellular changes over time which can sometimes lead to cancer. So, what makes one person more susceptible to persistent HPV infections than another?
Let’s explore a few root factors that could be at play. Addressing these root causes can help support the body to clear HPV and prevent cervical and other HPV-related cancers.
Nutrient Deficiencies
Nutrients form the backbone and catalysts for many reactions and processes in the body. Today, many individuals are deficient in important nutrients, and these deficiencies make it difficult for the body ecosystem to function optimally. Studies have found several nutrients to be correlated with HPV infections.
Persistent HPV infections are more common in individuals with low levels of folate (B9), vitamin A, vitamin C, vitamin E, and selenium. With these deficiencies, there is also an increased risk of progression to cervical cancer. HPV rates decline in individuals with higher levels of these nutrients.
The underlying action of these nutrients is to help support healthy immune function through inhibiting cancer cell growth and their powerful antioxidant activities.
Nutrient deficiencies can be corrected by consuming a diet rich in diverse whole foods, especially fruits and vegetables. We like to aim for 8 to 10 servings per day with at least one serving coming from green leafy vegetables.
Nutrient levels can also be corrected through supplementation. Papillex™ was formulated with this research in mind. Our nutritional supplement offers the daily recommended serving of micronutrients known to support HPV.
The Vaginal Microbiome
Within our body’s ecosystem exists separate micro-ecosystems including the vaginal microbiome. The vagina is home to trillions of microorganisms – bacteria, fungi, and viruses. These organisms play a role in the health and function of the vagina. When certain species overgrow or get depleted, health complications can occur.
The vaginal microbiome is largely populated by the Lactobacillus species. Studies find that HPV is more common in individuals with lower levels of Lactobacillus. In individuals with cervical dysplasia levels of unhealthy microbes like Prevotella, Sneathia, and Clostridiales are increased. Research also seems to indicate that HPV infection can disrupt the vaginal microflora, allowing the virus to persist.
Screening for vaginal infections like bacterial vaginosis, candida, and trichomonas vaginalis can help detect if there is an underlying imbalance and inform how to treat it. If you notice any changes in vaginal symptoms such as irritation, redness, pain, or changes to discharge, contact your doctor.
Taking care of your vaginal health is just like taking care of your overall health - eat a nutrient-rich diet, reduce sugar intake and processed food, and fill up on those pre-biotics and probiotics. Maintain proper hygiene practices by avoiding douches and soaps, using organic, scent-free personal care products, and cotton underwear. Safe sex practices are also important to your overall wellbeing - wearing condoms can reduce exposure to other bacteria and sexually transmitted infections as well as maintain vaginal pH.
Inflammation
Inflammation is a natural immune response to repair tissue damage and defend the body against invaders. However, unchecked and chronic inflammation is at the root of many chronic diseases.
It is helpful to think of the body as one interconnected ecosystem when considering the impact of inflammation on cervical health. When inflammation is out of balance, it can contribute to the body’s vulnerability to tissue damage.
Research has found inflammation and oxidative stress to play a role in HPV persistence. The HPV virus is better able to infiltrate into the cells when the tissue is inflamed. Chronic inflammation also helps cells proliferate over time, allowing for those cervical cell changes to occur. In addition, the HPV itself is also inflammatory and its cellular process further induces inflammation at the local site.
Reducing inflammation is another whole-body approach. Dietary factors play a role in supplying the body with antioxidants, known to balance inflammatory oxidative processes. Antioxidants are best obtained from eating a diverse diet of whole foods. We also recommend reducing exposure to inflammatory triggers like cigarette smoke, alcohol, and processed foods (trans fats and refined carbohydrates) as well as managing blood sugar through consuming adequate protein, fats, and complex carbohydrates to keep inflammation down. In addition to dietary changes, getting 7-8 hours of good quality sleep per night is crucial for the immune system.
Genetics
Certain genetic factors have also been explored for their role in HPV. Studies suggest there is a familial predisposition to cervical cancer. More specifically, research indicates that individuals whose mother or sister had HPV have an increased chance of developing cervical dysplasia and cervical cancer.
This increased risk could be due to several factors. Certain genes were found to be associated with HPV risk as well as HLA alleles. A person’s genotype may also influence risk behaviors that influence HPV.
Our genes may also impact our DNA repair and detoxification pathways. Associations between the MTHFR gene and cervical cancer may also exist. MTHFR plays a role in converting dietary folate into folic acid to be used in detoxification and cellular repair pathways. An MTHFR mutation increases the risk of several diseases including heart disease, colon cancer, and breast cancer. Some evidence suggests there is a link between genetic variants of MTHFR and cervical cancer, but more research is needed. Increasing dietary folate through intake of leafy green vegetables, beans, and supplementation, can help support this pathway.
Hormones
Hormones also play an important role as the chemical messengers that act throughout the body. Hormones were first thought to play a role in HPV infections following findings that HPV infections were more common in individuals on oral contraceptive pills and after having multiple pregnancies. The sex hormone, estrogen, is thought to explain why rates of cervical dysplasia increase in these groups.
Reducing exposure to xenoestrogens, estrogens found outside the body can help reduce this risk. Consider non-hormonal methods of birth control as a way to reduce risk. Again, diet and lifestyle factors play a role in supporting healthy hormone production and function. A diet rich in cruciferous vegetables (broccoli, cabbage, and kale) can help support estrogen detoxification and clearance. Intake of phytoestrogens like flaxseed and soy can help support a healthy hormone balance.
Why lifestyle is key
The good thing is most of these factors are modifiable through lifestyle practices. The daily choices you make can influence your likelihood of developing cervical cancer or other HPV complications.
As we have said, supporting the body against invaders like HPV is a whole systems approach. Focusing on a nutrient-rich diet, reducing stress and exposure to harmful chemicals, and targeted supplementation can help address many of the underlying root causes that lead one to develop complications of HPV.
Jan 03, 2022
5 min read
Sulfated Polysaccharides and HPV
Adrienne Hill-Strathy
Within the world of plants and fungi lie a vast array of medicinal compounds. Sulfated polysaccharides are powerful therapeutic compounds being explored for their anti-viral activity. These polysaccharides are shown to have potent anti-viral effects against viruses like the human papillomavirus (HPV) and the herpes virus (HSV).
Sulfated polysaccharides include compounds like heparin, cellulose sulfate, and dextran sulfate. Structurally, these compounds look very similar to heparan sulfate, an HPV cell-attachment factor. These compounds are found to inhibit papillomavirus and herpes infections due to their ability to block the viruses from attaching to healthy cells.
These polysaccharides also contain potent anti-inflammatory and antioxidant properties that help support cellular health and prevent tumor progression.
Where can you find these potent polysaccharides? Sulfated polysaccharides can be found in some species of medicinal mushroom as well as marine plants like red and brown algae.
Red Algae – Irish Moss (Chondrus crispus)
Irish moss is a type of seaweed or algae that is found on the Atlantic coast in Britain, Europe, and North America. The moss is rich in the sulfated polysaccharide carrageenan. You might know carrageenan from the back of your almond milk or yogurt. It is commonly used as a stabilizer and emulsifier in food products. The carrageenan found in common packaged foods is chemically processed and may even have negative health effects. However, consuming the moss in its pure form offers a range of beneficial vitamins and nutrients. Keep reading for a recipe.
In addition to its rich carrageenan content, Irish moss is also rich in other minerals like iodine, important for thyroid health. It also contains omega-3 fatty acids, which can reduce the risk of heart disease and high blood pressure. The moss also contains a carotenoid called fucoxanthin, which benefits blood sugar regulation and acts as an antioxidant, which we know is important for fighting HPV. Irish moss has been consumed for centuries and was used as a nutrient supply during times of famine.
Carrageenan acts as a potent HPV inhibitor by blocking HPV from binding to its attachment sites. Considering condom use is minimally effective in preventing HPV infection, carrageenan is being explored as a topical microbicide to be used preventatively against HSV, HIV, and HPV. The inhibitory effect appears to be strongest for HPV compared to HSV and HIV. Topical applications were found to be safe and well-tolerated, reporting no increased risk of reproductive tract infections or irritations. So far, carrageenan-containing sexual lubricants have been found to be effective at blocking HPV16.
Brown Algae – Fucoidan
Brown seaweeds contain a sulfated polysaccharide, called fucoidan. Fucoidan is a sulfated alpha L-fucan that has been found to support the immune system, reduce inflammation, and have an impact on blood pressure and infection. Animal studies have shown fucoidan to have a protective effect against liver injury by suppressing inflammatory mediators and increase the production of liver-protective enzymes. The anti-viral activity of fucoidan comes from its natural killer cell stimulation which promotes immune modulation and antitumor effects.
Brown algae also contain fucoxanthin, an antioxidant that gives algae its brown color, as well as other microminerals like iodine for thyroid health.
Fucoidan in brown seaweeds has been reported to possess anti-viral activities against viruses like HIV and HSV. The compound acts by inhibiting virus and entry and replication. More human studies are still needed to support its effects, but the compound could be used preventatively to reduce viral infections.
Lentinus Edodes- Shiitake mushroom
Shiitake mushrooms are one of the most well-known mushroom species. Medicinally, the shiitake mushroom is shown to be effective in the treatment of prostate cancer, can help lower high cholesterol, stimulates the activity of immune cells, and has antiviral and antibacterial properties.
The potent medicinal properties come from their high polysaccharide content of Beta-D-glucans. These glucans have been found to enhance the number of immune cells and have antiviral activity against the poliovirus and herpesvirus.
The beta-D-glucans found in shiitake aid in slowing tumor growth and kill viruses and other microbes.
Agaricus Blazei- Almond Mushroom
Another medicinal mushroom rich in polysaccharides is Agaricus Blazei, also called Agaricus subrufescens. Agaricus is a Brazilian basidiomycete often consumed as food or in tea to help with emotional stress, high cholesterol, diabetes, and gastric disorders.
Agaricus contains active compounds that have repeatedly been shown to activate the immune system and prevent the herpes virus from attaching to and infecting healthy cells. The compound also has anti-inflammatory and antioxidant properties, helping maintain the overall health of the cells.
Reaping the many therapeutic benefits of mushrooms isn’t as easy as eating sauteed mushrooms. Medicinal compounds must be extracted through water or alcohol-based decoctions. These powerful extracts are then taken in tinctures or powdered form.
What are the risks to consuming sulfated polysaccharides?
While generally quite safe for use, mushrooms like shiitake may cause an elevation in white blood cells, upset the stomach, and skin inflammation. Agaricus extracts can cause hypoglycemia, nausea, diarrhea, and upset stomach. Few have also reported liver damage and allergic reactions.
Because seaweeds contain iodine, there is a risk of consuming too much iodine and disrupting thyroid function. Sea vegetables like algae may also be exposed to environmental contaminants like arsenic and mercury. Make sure to purchase these supplements from a reputable source. Algae should not be taken with anticoagulant drugs like warfarin and heparin.
Given the immune stimulatory effects of sulfated polysaccharides, supplements should be taken with caution in individuals with autoimmune or immune system conditions. We always recommend seeking advice from a health care provider before starting any supplement or treatment.
Image from: https://divascancook.com/how-to-make-sea-moss-gel-recipe/
How to reap the benefits of Irish Moss
Irish moss can be bought in raw form or cultured into a gel. The moss can then be used topically or ingested. If taken orally, add 1 heaping tablespoon into a smoothie with frozen mangoes and dates.
2 oz of raw Irish moss
1700 ml of spring water
To make:
Wash moss thoroughly in filtered water.
Soak 2 ounces of dried Irish Moss on the counter in 1700 ml filtered water for one day.
Simmer on low until a gel is formed.
Irish moss has minimal taste, so it is perfect to blend into smoothies, juices, and soups or strews.
Store in the refrigerator for up to 2-3 weeks or kept frozen.
Nov 15, 2021
5 min read
Seven Steps to Healthier Habits
Adrienne Hill-Strathy
When it comes to taking care of our health, daily habits are key. It is the consistent things we do every day that add up to enhance our overall wellness and prevent disease.
Habits are powerful because they become automatic behaviors that we do with minimal thought or effort. Over time, these small efforts accumulate and have a significant impact. For instance, most of us brush our teeth twice a day without much complaint or question, but this little action has a huge impact. Brushing helps to prevent cavities and supports our oral health and digestive system.
Habits can also be harmful. Smoking, drinking, overeating, negative self-talk, or too much time on technology can have negative impacts on our health over time. When forming new habits, we want to do our best to engage in the things we know will benefit our wellbeing and reduce harmful behaviors.
When it comes to supporting the immune system to defend against HPV, habits play an important role. Even if you already live a healthy lifestyle, we can all benefit from adopting an extra healthy habit or two.
So, how do you create healthier habits and make them stick?
First, start by identifying what health goals you want to achieve
Before making any lifestyle change it is important to understand your why. Health will mean different things for each of us so understanding why you want to change will help guide the habits you target.
For example, you may want to support your body against HPV. With that goal in mind, you may want to quit smoking, incorporate an extra serving of green leafy vegetables into your diet, or go to bed earlier to get 7-8 hours of sleep. Your goal may be to feel more at peace. Habit for that may look like saying no to more engagements or setting aside time to meditate each morning. Spend some time identifying what you want and then brainstorm how you think you can get there.
Start small
Often when we are trying to make lifestyle changes, we can get overwhelmed by making too many big changes too quickly. When we feel overwhelmed, we are less likely to follow through with our intended actions. Remember to slow down and start with something small and achievable.
Try setting a time and place to complete your new habit. For example, “I am going to go for a walk every day after dinner”, is more realistic than “I am going to walk 5 km a day”. This helps keep your habits flexible and takes the pressure off. It also helps creates a ritual around the new habit which brings us to our next tip.
Creating rituals
Daily rituals are a great way to start implementing a new behavior into your routine. A helpful way to do this is to pair it with something you already do.
Let’s use brushing your teeth again because most of us do that daily. You may be trying to take new supplements to support your immune system. After brushing your teeth in the morning, you could take your supplements. Place your supplement container near your toothbrush so you are easily reminded. Soon, you will naturally pair teeth brushing with taking your supplements and a new habit is formed.
You could also try creating a ritual before bedtime, when putting your clothes on in the morning, or drinking your morning cup of coffee or tea. Take note of things you do every day and then see how you can pair the new behavior with what you already do.
Checking in through reflection
Things don’t always go as planned. Setting aside time each week to reflect on how you are doing and adjust accordingly can help you stay on track.
For example, schedule a Sunday evening check-in to write down how you did this week on your goals. Consider what went well and what you could do differently. Then plan accordingly for the next week. Maybe your goal was too ambitious - that is okay! Ask yourself, what could make it a little easier this week? Try rating how likely you would be to follow through on a scale of 0-10 (10 being very likely, 0 being not at all). If you score below a 7, that’s a sign to bring it back a level and make it easier.
Setting reminders
We all have busy lives and get caught up in things. Setting alarms, reminders, or scheduling in your habits helps you stay consistent. Maybe you want to set a reminder on your phone to take your supplements or drink water throughout the day. Use your calendar to schedule times to exercise, rest, or meal prep. That way even if you have a busy schedule, you can account for those healthy habits into your routine.
Accountability
Having someone to help hold you accountable for your health goals can support your success! Whether that’s a friend, family member, support group, partner, or practitioner, it’s helpful to have someone you can check in with. It can be especially helpful to find someone that will adopt healthy habits with you to encourage you when you’re not feeling up to it.
Be kind to yourself
Lastly, and most importantly, remember to show yourself compassion. Changing behaviors can be challenging. We are not going to be perfect all the time. Aim for doing the best you can. Put in the effort and be gentle with yourself on the rest - tomorrow is always a new day. One small setback doesn’t mean you can’t get up and try again! You can do this!
Oct 18, 2021
4 min read
The Nutrient Connection – How Micronutrients Could be at The Root of Your HPV.
Adrienne Hill-Strathy
When many of us think of the health benefits of food proteins, fats, and carbohydrates come to mind. These macronutrients make up the general composition of our foods but within them lie additional health-promoting compounds called micronutrients.
Micronutrients include trace minerals and vitamins that support the normal growth and development of living organisms. Without them, body systems like the immune system, nervous system, and digestive system can become impaired.
Many individuals are deficient in micronutrients. This can be due to low intake of dietary sources like fruits and vegetables and high intake of processed and nutrient-poor foods. Additionally, it is thought that the micronutrient quality of our fresh food has declined in recent years due to industrial agricultural production.
This micronutrient deficiency may be at the root of why some people struggle to eradicate HPV infections compared to others who clear the virus more easily. Several micronutrients have been specifically found to be low in individuals with HPV and cervical dysplasia - we’ll outline them below.
Portrait of female gatherer gathering organic vegetables with a wicker basket at orchard
The Key Players
Folate – Vitamin B9
Most people know of folate as an important nutrient for fetal development that should be taken during pregnancy. In addition to supporting a healthy pregnancy, Folate also plays a role in DNA production and red and white blood cell formation, and also plays an important role in HPV.
When folate levels are low, the body has trouble maintaining a process called methylation. Methylation helps support cardiovascular, neurological, and reproductive health. When the process is impaired, it can increase levels of an inflammatory compound called homocysteine. This compound can increase the risk of heart disease and impact gene regulation that helps regulate cancer cell growth.
There is a strong association found between folate deficiency and cervical dysplasia. Several studies have found that high blood levels are associated with a lower risk of cervical dysplasia and HPV and increased risk with low blood folate. Studies have also demonstrated that supplementation with folate may reduce the risk of cervical cancer.
Low dietary intake of folate may not be solely to blame for deficiencies. Some individuals have SNP’s in their genetic pathway that prevents them from converting dietary folate into its active form. These individuals may have higher levels of homocysteine and an increased risk of disease.
How to get your dose? Foods that contain folate include leafy greens, brussel sprouts, broccoli, and chickpeas. Folate can also be supplemented. The recommended daily intake of folate is 400 micrograms.
Lycopene and Carotenoids- Vitamin A
Vitamin A is derived from dietary intakes of those red, orange, and green-colored vegetables rich in lycopene and carotenoids. This vitamin also appears to play a role in cervical health.
Studies evaluating dietary intake and blood levels of Vitamin A found higher intake was associated with a reduced risk of cervical cancer. Whereas low dietary intake of carotenoids is associated with an increased risk of persistent HPV infections.
How to get your daily dose? To get more lycopene and carotenoids into the diet, aim for 6-8 servings of leafy greens, orange, red and yellow vegetables per day.
Foods rich in lycopene and carotenoids include: carrots, squash, tomatoes, broccoli, and red peppers. A dosage of 3000 mcg per day is recommended. Please note that Vitamin A should not be taken if pregnant, as excess stores can build up and cause birth defects.
Selenium
Selenium is another trace mineral that we must obtain from our diet. Selenium is important for thyroid function, reproductive health, and keeping the immune system running.
Many individuals are low in selenium due to the reduced soil quality of our foods. Low levels have been found to increase rates of cervical dysplasia. Selenium deficiency is thought to allow viral strains to mutate and progress.
How to get your daily dose? Selenium is found in high doses in brazil nuts. 3 nuts per day are adequate to reach the daily recommended dose of 200 mcg. Oysters have also been found to contain selenium.
Vitamin C
Who doesn’t love vitamin C? A powerful antioxidant that plays a role in many functions in the body. Vitamin C is important for immune system function, which is why we have all associated oranges and lemons with preventing colds and flu. Vitamin C also supports collagen production, iron absorption, and fuels and protects our cells.
Studies have found that higher intake of Vitamin C was associated with lower rates of HPV persistence compared to lower intake. Dietary supplements of Vitamin C were also found to reduce the risk of Cervical dysplasia in high-risk HPV infections.
How to get your daily dose? Foods like kiwis, red peppers, broccoli, citrus fruits, apples, and strawberries are high in vitamin C. The recommended daily intake is 75 to 90 milligrams. However, intake of up to 2000 mg a day is considered safe.
Vitamin E
Finally, Vitamin E deserves a mention - this vitamin is another powerful antioxidant found to protect against DNA damage and oxidative stress. Vitamin E may have anti-cancer effects.
A meta-analysis reviewing the relationship between vitamin E intake and blood levels of vitamin E has found the higher levels of vitamin E, the lower level of cervical dysplasia.
How to get your dose? Vitamin E is found in foods like sunflower seeds, almonds, peanuts, pumpkin, beet greens, spinach, and red bell pepper. The recommended daily intake is 15 milligrams per day.
Receiving our nutrients from foods is always the best method, however, it isn’t always easy to get our daily dose. That is why Papillex formulated its supplement with this research in mind to provide one supplement to meet all of your needs!
Sep 06, 2021
4 min read
Condyloma Acuminatum: Genital Warts
Adrienne Hill-Strathy
Condyloma Acuminatum is a fancy way of saying genital warts - a common symptom of a Human Papillomavirus (HPV) infection.
Genital warts can be alarming and irritating. If you are experiencing genital warts, you are probably wondering how you can get rid of them. Is there anything you can do naturally?
In this blog, we provide ways to respond to genital warts naturally, both internally and externally.
The HPV family
While most of the focus on HPV surrounds cervical cancer, the HPV family includes over 100 different viral strains, each having a slightly different impact on the body. HPV is responsible for common and plantar warts found on the hands and feet, as well as genital warts that grow around the vulva, vagina, penis, and scrotum.
Only a few of the strains of HPV have the potential to become carcinogenic, causing cervical, oral, and anal cancers.
90% of genital warts are linked to HPV strains 6 and 11: These strains are considered “low risk” because they rarely develop into cancer.
70% of cervical cancers are caused by HPV strains 16 and 18: These strains are known as the highest risk strains and can progress into cancer.
What do genital warts look like?
Genital warts look like soft, fleshy growths. They may appear as a single or in multiples, some describe them as looking like cauliflower. Genital warts can be irritating but are rarely painful.
Genital warts can affect both men and women. The estimated 5-year prevalence of genital warts is 1.3% in men and 1.7% in women.
Warts typically emerge around the genitals a few weeks to two to three months after infection. HPV is easily transmitted from one individual to another through skin-to-skin contact, most commonly through sexual activity. Even if the individual has no symptoms or the warts have gone away, they may still be able to transmit HPV.
If you suspect that you have genital warts, we recommend seeking advice from a medical professional. Other STIs, like herpes or syphilis, can present with similar symptoms and may warrant further treatment. The lesions may also be something harmless like a mole, ingrown hair, or skin tag - so it’s always better to check!
Can I naturally respond to genital warts?
Most people’s immune systems will naturally clear HPV infections in anywhere from a few months to a few years.
The immune system includes several immune molecules like natural killer cells, cytokines, and macrophages that identify and eradicate viral infections. The immune system also keeps cancer cell growth in check through a process of tumor cell identification and cell death.
A few natural compounds have been found to enhance these immune players, leading to viral clearance.
How to respond internally
Green tea extract: Green tea extract is a key player when it comes to antiviral support. Green tea is high in compounds called polyphenols that benefit the immune system. Two polyphenols, epigallocatechin gallate (EGCG) and polyphenol E are effective at treating cervical lesions and warts caused by HPV.
Drinking green tea as well as supplementation has been found to contribute health benefits and support wart clearance. If drinking tea isn’t your thing or you want to amplify your dose, Papillex supplies the recommended daily serving of green tea to support the immune system.
Diet: It is estimated that 80 percent of the immune system is located in the gut. So what we eat and put into the body plays an important role in our immune defense. Eating a diverse array of fruits and vegetables provides ample micro and macronutrients.
Amino acids obtained from proteins are essential for immune function as well as probiotics and fiber to support the intestinal microbiome. We also recommend trying to limit sugar, which can act as an immunosuppressant.
AHCC: Emerging research on a medicinal mushroom extract called AHCC may support the immune system in eradicating HPV that causes genital warts. AHCC has been found to enhance the production of NK cells and cytokines, known for their role in viral clearance. The extract has not been clinically tested on genital warts but has been found to help eradicate persistent high-risk HPV infections in individuals with cervical dysplasia.
How to respond externally
Topical treatment for genital warts: Conventional treatment offers several prescription chemical treatments that can be applied topically. Some topical treatments include Podofilox, a gel solution with active podophyllin, has been found to prevent local irritation, and Imiquimod, a topical immune modifier that comes in single-use packets. In addition, there are natural solutions on the market.
Green Tea Extract: Green tea extract has also been shown to have benefits when applied topically. The FDA has approved a standardized extract of green tea leaves for topical use on warts. The extract contains 15% catechins, the potent polyphenols found in green tea.
Research evaluating the use of green tea extract topically found it to be effective and safe. The study evaluated a 10% green tea catechin ointment on over 100 adults with genital warts. The findings showed that those that used the green tea were 2-fold more effective at clearing existing warts and preventing recurrence 12 weeks after treatment.
Tea tree oil: Tea tree is an antimicrobial herb that can be applied topically with a carrier oil such as coconut oil. Tea tree oil should not be taken internally or applied to the vaginal canal.
One case report evaluating the use of tea tree oil twice daily with a carrier oil found clearance within 10-20 days for warts to disappear completely. More research is needed to determine the effectiveness on genital warts in larger, randomized clinical trials.
Bottom Line
Few people are willing to talk about their experience with genital warts, and this stigma makes it difficult to know what to do. We hope this article gives you an assurance that genital warts are harmless and mostly self-limiting.
If you are having trouble clearing genital warts, there are natural ways to respond both internally and externally. When in doubt, we always recommend you consult with a trusted natural health practitioner to find what works best for you.
Aug 23, 2021
5 min read
Adrienne Hill-Strathy
Let’s talk about inflammation.
Many have deemed inflammation the driver of all chronic diseases - but, inflammation is crucial to our survival and bodily protection. We need inflammation to heal.
So, what is the balance? And how can we find it?
This blog covers all of that and more - keep reading for all things inflammation.
Inflammation- friend or foe?
Inflammation is the immune system’s first line of defense when fighting off pathogens like bacteria and viruses and helps us heal from injury. The inflammatory response plays a crucial role in combating infection and repairing tissue damage. Without inflammation, the body couldn’t heal.
Several immune molecules play a role in inflammation, including macrophages, fibroblasts, mast cells, and dendritic cells. These molecules circulate in the blood until they pick up on invaders or cell damage to direct their response.
With all of that said, chronic activation of the inflammatory response is at the root of many diseases.
Our understanding of the connection between inflammation and disease has grown, and so have our tools to balance its response. Medicinal mushrooms are one way we can support the immune system in modulating the inflammatory response.
Types of inflammation:
Acute inflammation: Acute inflammation is the first player to act in the immune response. A scrape on your knee that turns red and hot, a runny nose, or a fever are all the body’s natural ways of healing. We have all experienced these acute inflammatory stressors and thank our body for its effective response.
Chronic inflammation: Chronic inflammation occurs when the immune system is constantly triggered. Instead of healing the body, the immune system creates too many pro-inflammatory molecules, like tumor necrosis factor (TNF), interleukins (ILs), prostaglandins, and free radicals - this excess causes cell damage and creates health issues.
Many factors contribute to chronic inflammation. Inflammation may be triggered by stress, foods, toxic chemicals, heavy metals, and infections. Diet plays a large role because 70-80 percent of the immune system is located in our gut. What we eat directly interacts with the immune system and can initiate an inflammatory response.
How do I know if I’m chronically inflamed?
Chronic inflammation can be hard to detect and can build up over time. Symptoms such as weight gain, fatigue, moodiness, pain, skin problems like psoriasis and eczema, allergies, and autoimmune conditions may indicate chronic inflammation.
You can also measure inflammation through blood tests. C-reactive protein (CRP) is a common inflammatory marker that can be measured in the blood. The optimal range of CRP is < 0.5 mg/L.
Homocysteine is another inflammatory amino acid linked to heart disease and other inflammatory conditions. The optimal range is <7 Umol/L.
How can I decrease inflammation?
Now that you know a bit more about optimal and chronic inflammation - what can you do?
Here is where the mushrooms step in.
Medicinal mushrooms and inflammation
Mushrooms have been used for centuries for their therapeutic effects on the body. Mushroom extracts have been used as immune modulators and for their anticancer, antibacterial, and antiviral properties. Medicinal mushrooms contain some of our most potent anti-inflammatory compounds.
Medicinal mushrooms contain active compounds that can modulate the inflammatory response. Mushrooms are rich in polysaccharides, phenolic and indolic compounds, mycosteroids, and fatty acids as well as other vitamins and biometals.
During chronic inflammation, the immune system is overproducing inflammatory mediators, leading to cell damage. The bioactive compounds found in mushrooms can reduce and suppress the production of inflammatory mediators through downregulating certain genes. This downregulation dampens the immune response, creating homeostasis and preventing chronic disease.
The powder of polysaccharides
Polysaccharides are one type of bioactive compound found in mushrooms. These polysaccharides inhibit inflammatory molecules including, IL-6, prostaglandins, and leukotrienes.
Glucans are one type of polysaccharide found to adjust the immune system by binding to receptors in the digestive tract and activating the immune response. The glucans stimulate the production of immune molecules such as natural killer cells, cytokines, and T helper cells. These immune molecules signal the rest of the immune system to kick into gear.
What mushrooms can help inflammation:
Reishi: Also called the mushroom of immortality, Reishi is rich in bioactive compounds including fatty acids, polysaccharides, and peptides found to inhibit inflammation. The polysaccharides found in Reishi may inhibit cancer cell growth and have anti-inflammatory properties with melanoma and breast cancer.
Chaga: Chaga mushrooms have also been found to have a potent anti-inflammatory effect. The mushroom has been found to have anti-inflammatory properties on mast cells and histamine responses. Histamine and mast cells are released in response to tissue damage and other inflammatory conditions and affect the microvasculature.
AHCC: Stands for Active Hexose Correlated Compound, a mushroom extract that contains both alpha and beta-glucans that modulate the immune system. AHCC is a potent immune modulator that stimulates natural killer cells, cytokine, and macrophages. The extract has been evaluated as general immune support as well as an adjunctive in the treatment of cancers and viral infections.
Of course, supporting a healthy inflammatory response involves more than just a mushroom supplement. Diet, stress, environmental toxins, etc. also play a vital role. It is important to assess your lifestyle and make adjustments based on your specific risk factors. We recommend including a few mushrooms in your daily routine to offer extra immune support and keep you in balance.
Jul 12, 2021
4 min read
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