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Tips for Safer Sex with HPV

Victoria Gasparini
HPV is one of the most common sexually transmitted infections, affecting 80% of sexually active women. In fact, most sexually active men and women will contract some strain of HPV at some point in their lives. Unlike many STI’s, HPV does not have a known cure. Because of this, the typical advice around sexual abstinence with sexually transmitted infections is likely not sustainable.  If you’ve tested positive for HPV, the best thing you can do for both you and your sexual partners health is educate yourself on safe sex, while addressing the infection and practicing methods to reduce viral transmission. With that being said, here are 3 tips you can take to practice safer sex with HPV, and reduce your risk of spread. Talk to your doctor about getting vaccinated against HPV.  Both you and your partner may benefit from the protection of vaccination. The HPV vaccine prevents from many dominant strains of the virus, which reduces your risk of commonly associated cancers like cervical, anal, and oropharyngeal. The HPV vaccine also protects against occurrence of genital warts. Vaccination is NOT a substitute for regular screening, and therefore all people with a cervix need to keep up with their regular pap tests. Vaccination is a personal decision that should be discussed with your healthcare provider. Use protection each time you engage in sexual activity Keep in mind, HPV can be spread through any kind of sexual activity including vaginal, anal and oral sex. Though not 100% effective at stopping the spread of STD’s, condoms and dental dams can drastically reduce your risk of spreading HPV to your partner when engaging in sexual activity. It is important to know that HPV spreads through skin cells, so condoms do not provide complete protection.  Get tested. Regularly.  Early detection of HPV and any other STI’s is crucial to your health. Both you and your partner(s) should consider getting tested and staying in the know on your sexual health. Consider getting tested with each new sexual partner, as well as maintaining regular screening as recommended by your physician. A pap smear can help identify pre-cancerous and other cell changes of the cervix that may put you at risk for cervical cancer. The HPV test identifies the virus that can be responsible for these cell changes. Discuss your testing options with your physician. Manage HPV with lifestyle and dietary changes If you have chronically occurring genital warts, bumps, lesions or sores, you should check with your doctor before engaging in sexual activity. Though these often go away on their own, your doctor may be able to provide you with some options to speed recovery. There are also many dietary and lifestyle changes that can help clear or suppress the virus, making it less likely to spread infection through sexual activity. In addition to these changes, products like Papillex, AHCC and our new supplement for HSV, Simplix, may speed up the healing process. In addition to common prevention methods, foundational lifestyle approaches like adequate sleep hygiene, a reduction in stress, and adding antioxidants through food and supplementation are tried and true ways to suppress HPV.
Jul 11, 2022
2 min read

How Managing Blood Sugar Can Help You Heal HPV

Victoria Gasparini
Did you know that nearly 80% of non-diabetics have glucose spikes everyday, without even knowing it. Many of us go about our daily lives dealing with digestive complaints, mood swings, PMS, insomnia, accelerated aging, infertility, hormonal imbalance, weight gain, cravings and increased susceptibility to infections - without asking why. Glucose spikes can actually be the root cause of these symptoms. In fact, glucose spikes are actually more harmful to our health and well-being than a higher, but steadier glucose level. What are glucose spikes? Glucose is a simple sugar that is an essential fuel source for the body and brain, and is a necessary molecule in our diets. However, with an overabundance of high-sugar, carbohydrate-rich foods in our modern day diets, our body’s have to respond to much higher levels of glucose than we are wired for.  When we eat a food rich in simple carbohydrates, like a bowl of cereal for example, our body breaks it down into simple sugars and transports these sugars to the bloodstream. Once there, the pancreas will pump out insulin which acts as a transporter, bringing glucose (sugars) into the cells. When this happens, our glucose spikes and then drops really low, usually causing us to feel an immediate satisfaction, followed by increased cravings, sleepiness, and more. Though this is a normal and healthy response to high amounts of sugar circulating the blood, if there is a chronic, excessive intake of glucose, and therefore a chronic release of insulin into the bloodstream - we often end up with something called Insulin resistance, where our bodies no longer respond as efficiently to insulin, and we end up with lots of free-floating sugars in the bloodstream that should not be there. Insulin resistance is a precursor to diabetes, and is often seen in women with PCOS as well. How do glucose spikes impact your ability to combat HPV? Okay, so what do glucose spikes have to do with your ability to clear HPV? Well, research finds that glucose spikes and insulin resistance both contribute to malfunctioning immunity and the inability to effectively fight off infections. One study found that glucose spikes inhibited microbial killing and phagocytosis, as well as increased the production of inflammatory cytokines in otherwise healthy subjects. Trials continue to show that by managing glucose spikes, we can reduce susceptibility to infection and allow us to create healthy immune responses to infections when necessary.  Because HPV is a viral infection, supporting the immune system's ability to fight infections is the most important effort you can make when healing with HPV.  What causes glucose spikes? Many lifestyle and dietary habits can be contributing to glucose spikes. As mentioned above, simple carbohydrates on their own, like a bowl of cereal, coffee drinks on an empty stomach, dried or juiced fruits, and other high-sugar foods all contribute to glucose spikes and the susceptibility to insulin resistance seen in diabetics and patients with polycystic ovary syndrome (PCOS).  But it is not just diet that leaves us vulnerable to glucose spikes. PMS, lack of sleep, and genetics all play a role in our susceptibility to glucose spikes and insulin resistance as well. Aside from not being able to change or control your genetics, there are many dietary and lifestyle changes (surprisingly some pretty easy ones, too) that can lessen these spikes and thereby reduce your symptoms.  What can we do to lessen glucose spikes? Below are 5 easy-to-try tips for managing glucose and helping your body fight HPV. Pair your carb-heavy foods with a healthy fat or protein source. Research finds that glucose spikes are significantly reduced when we pair our carbs with fat or protein. For example, eating a slice of white bread with jam will create a much more drastic glucose spike than if you ate your bread with a nut butter (fat) and maybe some hemp hearts (protein).  With this amazing tip, you can eat your favorite goods, while being smart about glucose control. Combining these carb and starch heavy foods with fibre, fat and/or protein creates a much smaller glucose spike and prevents us from that post-glucose crash. This helps us achieve a steady mood, less cravings, more satiety and a better immune response. Save the best for last The order in which you eat your food actually has a significant impact on your glucose spike. For example, if your plate has salad, french fries and chicken - it is actually best to start with your salad, then eat your protein, and save those yummy french fries for last.  The science behind this is that veggies contain a ton of fibre, which creates a sort of “fibre mesh” in the small intestine, delaying gastric emptying and lessening the glucose response to whatever else is on your plate. Studies have found that by simply eating your food in this order, you can reduce glucose spikes by up to 73%.  Additionally, if your salad has vinegar on it, even better. Research finds vinegar before meals reduces your glucose spikes by 30%. So, leave your carbohydrate-rich foods for last to reduce your glucose spike.  Go for a walk after meals This is a very simple and effective technique to reduce glucose spikes. After a carb-heavy meal, head outside and walk, or even just get active for 10 minutes. When we are active, our muscles need energy. A fast way for those muscles to get energy and help you power through your movement, is to take up glucose that is floating through the bloodstream. This is an awesome way to reduce glucose spikes while also releasing those happy chemicals we get when we move our bodies.  Get adequate rest Those that do not get much sleep are at an increased risk of glucose spikes throughout the day compared to those who get 7-8 hours of quality rest each night. Prioritize sleep for better glucose management.  Try AHCC Not only is AHCC wonderful for supporting your immune response with HPV (and other viral infections), but there’s actually research that finds AHCC can reduce glucose spikes and help us to better manage our blood sugars.
Jun 27, 2022
5 min read

Shiitake Mushrooms for Cold Sores and Herpes Simplex

Jenny Henderson
If you are a fan of Asian cuisine you have very probably eaten, or at least are aware of shiitake mushrooms. These delicious mushrooms, known by their latin name as Lentinula edodes, are also familiar to medical researchers. The research into the therapeutic properties of various mushrooms has been really taking off in recent years, and there are certain ‘favourites’ in the studies that seem to have quite a lot of potential, such as Reshi, Turkey Tail, Agaricus, and of course Shiitake. Some promising research is demonstrating potential benefit for Herpes Simplex virus infections such as cold sores. What are the benefits of Shiitake mushrooms? Shiitake mushroom extracts have been shown to have a variety of therapeutic actions, such as being anti-inflammatory, immune-modulating, antioxidant, protective for the liver, cholesterol lowering, anti-tumor, antibacterial, and antiviral. What about herpes virus? Shiitake compounds have been studied to observe their effects on many viruses, including the Herpes Simplex virus which causes cold sores and genital herpes. Several laboratory investigations reported that the main way in which the mushroom extracts worked against the virus was by preventing it’s ability to replicate within the cells.  Since the herpes virus has the ability to evade natural immune responses and enter into a latent stage in the body (i.e. hide out in an inactivated state), it is difficult to actually be completely free of it. The best treatment strategy then is to prevent or reduce the likelihood of re-activation of the virus, and subsequent replication. Shiitake mushroom extracts are promising candidates as agent that can support the body in preventing reactivation, replicating, and boosting the natural defence systems.  What are these mushroom extracts? The principal active compounds in antiviral mushroom extracts such as the ones that can be found in Shiitake are called polysaccharides. These are complex chained molecules that have the ability to physically interact with immune factors as well as viral particles, to enhance or disrupt their functions respectively. According to quite a few studies, some of the most effective polysaccharides are the sulfated polysaccharides. The molecular sulfate groups that give them their name seemed to be directly related to their antiviral activity. Is Shiitake safe? Shiitake mushrooms are considered very safe - after all they are a very popular culinary mushroom eaten all over the world. The polysaccharide extracts also have excellent safety profiles, with very few minor side effects reported, such as nausea, and those are fairly rare. As always, we still recommend that you speak with a qualified health care practitioner before starting any new medicinal supplements. Respond with Confidence | Harness the Power of Shiitake Extract with Simplix References: https://pubmed.ncbi.nlm.nih.gov/20491636/ https://repositorio.uam.es/bitstream/handle/10486/660904/antiviral_santoyo_jfnr_2012.pdf;sequence=1
Jun 20, 2022
2 min read

HPV: 5 Things Every Woman Should Know

Victoria Gasparini
An HPV diagnosis can leave one feeling vulnerable, scared, overwhelmed and even ashamed. So when you take to google to find stories of others dealing with HPV, it can be disappointing to realize that there are not many resources associated with empowering, educating and empathizing with others going through a similar experience.  At Papillex, our goal is to be that voice. We want to ensure that you have access to informative content, quality supplements, and act as a sounding board for those with HPV (and HSV, too!). Below are 5 things we believe every woman should know about their HPV diagnosis.  HPV is common and nothing to be ashamed of Dr. Brene Brown defines shame as an “intensely painful feeling or experience of believing that we are flawed and unworthy of love and belonging”. To break through the barriers built by shame, one must be vulnerable. Vulnerability has the ability to transform fear and shame into belonging and acceptance.  HPV is nothing to be ashamed of. In fact, nearly 80% of people will have HPV at some point in their lives. However, because HPV is a sexually transmitted infection, there tends to be a stigma that prevents many from talking about the condition. Because of the shame many women feel, it can be tough to find support in our peers as it is not widely talked about. HPV is a virus. Viruses spread. This is a normal part of life, and the more we talk about it, the less shame and stigma we attach to it. Discussing and spreading awareness of HPV takes great vulnerability, but it also brings a sense of belonging to you and those around you going through the same thing. Having HPV does not mean you will get cancer. There are nearly 150 strains of HPV, with about 12 of them being linked to cervical cancer. Having HPV does not mean you will have cervical cancer, but it is important to be aware of your condition and keep up with regular screening, as well as lifestyle and dietary management to prevent disease progression. Talk to your doctor about vaccination, and remember to always practice safe sex by using protection like condoms or dental dams. Though these are not fool-proof, they do help to decrease the chances of transmission. A great practice is to strengthen your immune system through science-backed lifestyle changes like adequate sleep, increased consumption of antioxidant rich foods and powerful supplements like Papillex and AHCC. Smoking, excessive alcohol consumption and birth control all contribute to disease progression with HPV.  We have strong evidence to support the link between smoking and alcohol consumption and HPV disease progression. Birth control is another factor that can actually increase a woman's risk of cervical cancer. Studies find that for women with diagnosed HPV, the longer they use oral contraceptives, the higher their risk for cervical cancer. The good news is that once birth control is stopped, the risk does not continue.  Talk to your doctor about what this means for you. If you choose to be on an oral contraceptive, ensure timely screening and monitoring with your trusted health care provider.  You don’t need to “watch and wait”, you can often control HPV with diet and lifestyle  There are many ways to stay ahead of HPV with dietary and lifestyle changes. At Papillex, we strive to find the best available research on diet, supplementation and lifestyle used in the management of HPV.  Some of our favourite science-backed nutrients are folate, vitamin C, selenium, AHCC, carotenoids and more. We also advocate for a healthy lifestyle with lots of movement, stress-reduction, reduced alcohol and smoking consumption, and getting out in nature as much as possible. These practices can help you to better manage your health and stay on top of HPV. The old “watch and wait” approach is out-dated and leaves patients feeling disempowered. It helps to know you have options. There are other cancers caused by HPV Many of us know the risks for cervical cancer, but cancers of the vulva, vagina, penis, anus and oropharynx are also linked to particular strains of HPV. Throat cancer rates are drastically increasing in North America, so it is crucial to be aware of these so that you can get ahead of it. According to the CDC, 90% of both anal and cervical cancers are thought to be a result of HPV. HPV is linked to 70% of vaginal and vulvar cancers and 60% of penile cancers. Up to now, throat cancers were thought to be mostly caused by smoking and alcohol use, but more recent evidence finds that about 60-70% of oropharyngeal cancers may actually be linked to HPV.  Though not all HPV leads to cancer, prevention and early detection are only possible through adequate screening and remaining informed on your risks. Why watch and wait? Head to our instagram and our website for more ideas on how you can take control of your HPV today.
Jun 13, 2022
4 min read
Agaricus Mushroom for Herpes and Cold sores

Agaricus Mushroom for Herpes and Cold sores

Jenny Henderson
It is very possible that you may have been hearing more lately about the benefits of medicinal mushrooms. The amount of research that has been devoted to the health effects of various mushrooms in recent years as exploded.  There is already a fair body of evidence that demonstrates the power of mushrooms in benefiting the immune system, fighting cancer, reducing inflammation, supplying antioxidants, and fighting viruses, such as herpes and cold sores.  One of these mushrooms is a bit newer to the research scene than some of the veteran mushrooms like Reishi. We’re talking about Agaricus subrufescence (aka Agaricus blazei). Found in Brazil, this mushroom has long been used in globally for a variety of ailments, and is quite popular in Japan. What kind of research does Agaricus have? A lot of the research into this mushroom has focused on tumours and cancers, both in vitro as well as a some clinical trials. It appears that the extracts of Agaricus blazei have the ability to modulate the immune system to attack cancer cells, and to have direct anti-tumor effects (like inhibiting tumor growth). Clinical trials have also looked into the anti-inflammatory effects of Agaricus, in both healthy people, and those with inflammatory conditions like IBD. Traditional uses of Agaricus have often focused around reducing cholesterol, atherosclerosis, and liver ailments. Liver protection had been shown in studies, as well as benefits against diabetes, and viral infections.  What about the herpes and cold sores virus? It appears that Agaricus possesses anti-herpetic activity, meaning that it can act against the Herpes Simplex virus that causes cold sores and genital herpes. Laboratory studies have looked into how exactly it acts on the virus and found that generally the mushroom extracts bind with the virus and interfere with its ability to attach and enter healthy cells. What gives it these properties? There is a type compound found within Agaricus (as well as other medicinal mushrooms and marine algae) called polysaccharides. These varied and complex molecular chains all seem to have very beneficial functions, including anti-viral activity. They do not kill viruses, but they stimulate the immune system to target the invaders, as well as interfere with the virus itself, making it hard for them to enter cells and replicate. The most effective group of polysaccharides are called sulfated polysaccharides, because they have some sulfate groups attached to the chains. It is this sulfation that makes these compounds especially anti-viral, and potentially beneficial against herpes and cold sores. Is Agaricus safe? Agaricus subrufescence as an edible mushroom has an excellent safety profile and is generally considered safe to consume. Extracts of this mushrooms also are generally considered safe, with very few reports of adverse events. Of course, as always, we recommend that you speak to a qualified health care practitioner before starting a new medicinal supplement. The right combination is already here - Respond with Confidence References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730566/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285126/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716167/
Jun 06, 2022
2 min read
Proven Ways to Strengthen your Immune System this Summer

Proven Ways to Strengthen your Immune System this Summer

Victoria Gasparini
There are nearly 150 types of HPV, and thankfully, 90% of cases tend to resolve within a few years of infection. This is because the immune system does an impeccable job of clearing the virus. For others, the virus can lay dormant, not having any major implications on your health. However, some cases of HPV are higher risk, and put us at an increased chance of developing cancers of the cervix, throat, and more. One of the best things you can do for your health after receiving an HPV diagnosis (or before receiving one, because prevention is key), is to build and strengthen your immune system so it can adequately clear or suppress the virus. Thankfully, there are many ways we can do this.  First Things First, Know your Modifiable Risk Factors - and Eliminate Them. There are many lifestyle changes that have a significant impact on your immune health and on your body's ability to clear a virus. For instance, smoking and excessive alcohol consumption are both factors that increase your risk of abnormal pap smears and HPV progression. Research finds that smoking tends to increase prevalence of HPV infections by way of suppressing immune function and up-regulating inflammation. Additionally, smoking causes DNA damage and increased cellular proliferation, resulting in a higher incidence and susceptibility to HPV infection, and an increased risk of cancers of the cervix, head and neck. An in-vitro study found a potential link between carcinogen benzo(a)pyrene (in cigarettes) and abnormal cervical cells.  Research also finds that both excessive alcohol consumption and acute binge drinking can increase incidence of persistent HPV and associated symptoms, by disrupting and suppressing immune function. When assessing how alcohol impacts our ability to fight infections, it is important to look at the GI tract. Alcohol's first point of contact is in the gut before entering the bloodstream. With nearly 80% of our immune system residing in the gut, it’s no wonder that alcohol has an impact on immunity.  Alcohol acts as a disruptor to the gut epithelium, damaging T cells and neutrophils in the GI tract thereby facilitating the leakage of microbes through the damaged gut barrier and into circulation. Studies find that it might not only be excessive drinking, but also acute binging of alcohol that has the ability to suppress the immune system, affecting our ability to fight infections like HPV.  Add Science-backed Nutrients to your Diet Carotenoids  Carotenoids are a colourful class of compounds including lutein, lycopene and zeaxanthin. These orange, yellow and red pigments are naturally occurring in many fruits and veggies such as carrots, squash, bell peppers, mangoes, kale and spinach, to name just a few. Carotenoids play an essential role in modulating immune function and higher levels of carotenoids in the diet are linked with an increased clearance of HPV, especially in early stage infections. Additionally, carotenoids play an essential role in disease prevention, including cancers.   Sulforaphane  Sulforaphane is a powerful antioxidant that aids in detoxification, among other benefits. Sulforaphane is found in broccoli, cauliflower, cabbage and arugula, with the highest amounts in broccoli sprouts. When we consume foods with sulforaphane, it breaks down into two metabolites - DIM and I3C. These compounds are powerful cancer fighters. In fact, researchers have even coined the phrase “green chemoprevention” in relation to sulforaphane's anti-cancer properties. Epidemiological studies emphasize sulforaphanes role as an alternative agent in cancer prevention. Folate  Our immune system is greatly affected by folate deficiencies. Animal studies have found that folate deficiency causes alterations in the thymus, resulting in decreased ability for T lymphocytes to target pathogens, as well as decreased antibody response to various pathogens. Science has found an association between folate deficiency and cervical dysplasia. Vitamin C  Vitamin C has many crucial functions to protect the health and integrity of our cells. Studies find that vitamin C intake reduces risk of progression of high-risk HPV to cervical cancer, and can improve cervical dysplasia. Vitamin C is able to neutralize pathogens and inflammation, helping our cells perform their jobs effectively. A study in the journal of infectious diseases finds that risk of persistent HPV was lower in those with higher intakes of vitamin C. Additionally, studies have found a link between an oral intake of 1000mg of vitamin C per day and a shortened duration of genital wart presence, and a decreased rate of occurrence compared to controls.  Selenium   Selenium is a crucial mineral, required for hormone production and balancing oxidative stress. Viral infections may increase our body’s requirements for selenium because of the increased production of reactive oxygen species (ROS). Experimental animal studies have found that selenium may have anti-cancer activity in cervical cancers induced by HPV infection, with epidemiological studies finding that cervical cancer patients have decreased tissue concentrations of selenium. Additionally, a randomized, double-blind clinical trial of 58 Iranian women with biopsy indicated CIN1, found that 200mcg of selenium daily vs. placebo for 6 months demonstrated a regression of CIN1 compared with control. Due to the many mechanisms of selenium on the immune system such as its protective and anti-viral properties, selenium may aid in both treatment and prevention of HPV, and potentially cervical cancers induced by HPV.  All of these nutrients (and more) can all be found in therapeutic dosages in Papillex. Manage your Stress  Studies continuously find a connection between stress and its impact on immunity, which is supported in pathogenesis and persistence of HPV infections. You cannot always control stressful events from occurring, but you can manage perceived stress through methods of talk therapy, finding good friends to chat with, getting adequate sleep and nutrients, and getting outside in nature. Reducing perceived stressors can help with HPV disease management and progression and is an important part of any HPV treatment plan.  An HPV diagnosis can be overwhelming and scary. The good news is, there are many lifestyle and dietary changes that can aid in the healing of HPV. Building and strengthening your immune system is a great place to start.
May 30, 2022
4 min read
Top 5 Overlooked Foods for Supporting Immune Health

Top 5 Overlooked Foods for Supporting Immune Health

Adrienne Hill-Strathy
At Papillex, we are all about focusing on the factors we can control to positively impact our overall health. With that philosophy in mind, today we’re talking about food! Food plays a powerful role when it comes to supporting our immune health. The array of micronutrients we obtain from our food is necessary for the immune system to mount and sustain a response against pathogens and invaders like the human papillomavirus (HPV). Consuming a diverse, whole-food diet is number one in getting our supply of vitamins, minerals, and other phytochemicals. We’ve outlined a few of our favorite foods that can support our immune system on a daily basis.    Citrus fruits Many of us jump to citrus fruits when it comes to supporting our immune system--for good reason! Citrus fruits like grapefruit, oranges, lemons, and limes are a great source of vitamin C, magnesium, B vitamins, potassium, phosphorus, magnesium, and copper. Vitamin C in particular plays an important role in many cellular immune functions. The micronutrient has been found to help stimulate immune molecules like neutrophils, which help identify and clear away invaders. Vitamin C has been found to help decrease the severity and duration of colds and flu. Vitamin C can be depleted due to pollution, smoking, infections, and other diseases that increase oxidative stress. Studies have also shown that higher levels of Vitamin C might help reduce cellular changes due to HPV. Citrus is also a source of phenolic compounds and terpenes. These antioxidants have anti-cancer and anti-inflammatory properties. These compounds and Vitamin C work together to have a synergistic action in supporting your immunity. Consuming whole citrus fruit (not the juiced form) is also a good source of fiber. Fiber helps support a healthy gut microbiome, which is intricately connected to our immune system. Cruciferous vegetables Cruciferous vegetables are also known as the Brassica family, they include some of our favorites--broccoli, Brussel sprouts, collards, red cabbage, kale, and asparagus. These crunchy vegetables contain phytochemicals that are high in antioxidants called isothiocyanates. They are also rich in sulfur, folate, vitamin K, and vitamin B6. Regularly consuming cruciferous vegetables can help support DNA repair. Sulfur also helps recycle the antioxidant glutathione. The Brassica family also contains a rich source of sulforaphane, which is broken down into two powerful antioxidants, Indole 3 carbinol, and DIM. The compounds have been found to have anti-cancer properties and help regress cervical dysplasia. DIM is one of the ingredients found in Papillex. Cruciferous vegetables also benefit gut health due to their high fiber content, phytonutrients, and other vitamins and minerals. Lightly cooking these dense vegetables can help make them easier to digest and be utilized by the body. Ginger We have all tasted the warm, healing properties of ginger. Ginger has been used for centuries around the world in teas, dishes, and as a medicinal compound. The pungent rhizome contains the compounds gingerol, shogaol, and paradols. The anti-inflammatory and antioxidant properties of ginger have been found to benefit a range of conditions including degenerative disorders, digestive health, nausea and vomiting, diabetes, and cancer. The antimicrobial properties of ginger also help treat infectious diseases. The research suggests the anti-cancer properties of ginger come from its inhibitory effects on cell proliferation and cell death. Ginger can also suppress inflammation and DNA damage. Studies have shown that ginger can play a role in many cellular pathways that impact the prevention and treatment of cervical cancer. Garlic Garlic is another dietary staple, used for centuries for its pungent flavor and many health benefits. A superfood for many reasons, garlic is chock-full of nutrients, amino acids, and fibers. It contains calcium, iron, magnesium, selenium, zinc, and vitamins B1, A, and C. Garlic’s medicinal properties come from its concentration of sulfur-containing compounds like allicin and ajoene. Allicin helps support the immune system by reducing inflammation and stimulating immune defenses. The compound gets activated when garlic is chopped. Once in the digestive tract, allicin helps inhibit the growth of pathogens it has even been found to protect from certain bacteria like Helicobacter pylori.  The compounds found in garlic also possess anti-cancer effects. Ajoene has been found to trigger cell death in leukemic cells. Compounds in garlic have also been studied for their role in inhibiting mammary, melanoma, colon cancer cell growth. Research into its effect on liver, prostate, bladder, and lung cancer is evolving.  Garlic also supports healthy gut flora. Garlic contains a prebiotic fiber called inulin that helps feed the growth of good gut bacteria. Mushrooms We couldn’t complete our favorite immune-supporting foods without mentioning mushrooms. Regularly consuming mushrooms like shiitake and white button, offer a supply of many therapeutic compounds including polysaccharides called beta-glucans. Beta-glucans help inhibit inflammatory molecules while stimulating immune receptors and molecules to defend against pathogens and viruses. Mushrooms are also a rich source of B vitamins, which help protect the heart and regulate the nervous system. They also contain copper and potassium. A study researched participants that consumed 5 or 10 grams of shiitake mushrooms daily for a month. They found an increase in the production of T-cells and natural killer cells. Consuming mushrooms also increased the expression of receptors. The participant’s gut health was also impacted, with an increase in sIgA, a marker of healthy gut immunity. Of course, immune-supportive nutrients and phytochemicals are found across the food rainbow. Ideally, a diet rich in diverse plant and whole foods will support a healthy immune response. We hope this list offers a little extra inspiration for your next grocery haul. 
Apr 12, 2022
4 min read
How to Support Your Metabolic Health for HPV

How to Support Your Metabolic Health for HPV

Adrienne Hill-Strathy
What do you know about Metabolic health? If the answer is not much, that’s okay! Today we’re talking about how your metabolic health supports our overall health and wellbeing. Our metabolic health not only impacts our energy, but our memory, mood, skin, fertility, sexual health, and immune system. By understanding the basics of how our body uses energy and how we can support it, we can optimize our ability to defend against the persistence of viral infections like the human papillomavirus (HPV). Let’s dive in. What is Metabolic Health and Why Should you Care? Metabolism is the process by which we convert food into energy. When our metabolism is healthy, we have energy, normal blood pressure, blood sugar regulation, and limited inflammation. When our metabolic process becomes impaired our cells don’t function optimally and we are more vulnerable to developing disease. It is important to pay attention to our metabolic health because poor metabolic health underlies many chronic diseases, including persistent HPV infections. Unfortunately, poor metabolic health is more common than you think--you likely know friends or family members with diabetes, hypertension, obesity, or high cholesterol. It is estimated that 88% of the American population shows some signs of metabolic dysfunction. Around 33% of adults in the United States have metabolic syndrome. Metabolic syndrome is characterized by increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol and triglyceride levels. Metabolic syndrome is associated with an increase in chronic inflammation and oxidative stress, two factors that increase the risk of cancer and persistent HPV infections. Where Things Can Become Imbalanced The modern lifestyle is largely to blame for the high rates of metabolic dysfunction. Our diets are higher in processed and sugary foods, we are more sedentary than ever, get less quality sleep, and many of us live with chronic daily stressors that cause further hormonal and metabolic imbalance. All these factors and more, make it important to be aware of our metabolic health and how we can actively work to support it. One of the main ways our metabolism can become impaired is through our diet. When the body is taxed with large amounts of dietary carbohydrates, it can throw off our hormone balance and metabolism.   Blood sugar is one of our best markers to monitor metabolic health daily. Glucose is the primary fuel source for our cells. We obtain glucose when we break down carbohydrates and proteins from the diet. Glucose then signals the pancreas to secrete a hormone called insulin. Insulin is responsible for shuttling the glucose into our cells to be used as energy. The body stores some of this glucose in the muscles and liver for a backup energy supply. Some glucose also is stored in fat cells and processed by triglycerides. One of the impacts high blood sugars can have over time is a process called insulin resistance. Insulin resistance occurs when our cells become desensitized to insulin, preventing glucose from getting into our cells. Instead, the sugar remains elevated in the bloodstream. Excess glucose in the bloodstream leads to inflammation, oxidative stress, and can harden blood vessels over time. For optimal health, we want steady blood glucose and insulin levels over time. How Does Metabolic Health Impact HPV? You might wonder, how does this all play into HPV? Well, turns out the health of our cells influences many of the factors that put us at risk for HPV. As we’ve mentioned, inflammation and oxidative stress are increased when metabolism is dysfunctional. Metabolic dysfunction can also throw off our hormones and immune system. We know the immune system is so important for HPV clearance so when the system is impaired, it will be harder for the body to defend against viral invaders. Research has found some associations between poor metabolic health and HPV. A study looking at the relationship between blood glucose levels and cervical cancer cases found higher blood sugar was associated with a poorer prognosis of cervical cancer. There is also some evidence that suggests individuals with diabetes require more treatment for genital warts from HPV. How do I Assess my Metabolic Health? We typically measure our metabolism using five biomarkers: blood sugar, triglycerides, high-density lipoprotein (HDL) cholesterol, blood pressure, and waist circumference. Your doctor has probably screened you for some of these at some point. Many metabolic assessments are included in regular screening and medical check-ups. Obtaining regular blood pressure screening and labs is the best way to assess metabolic health over time. Basic blood tests to help assess your metabolic health: Cholesterol Panel: A cholesterol panel is commonly used to assess cardiovascular risk. The panel measures cholesterol levels and triglycerides. Triglycerides are a part of lipid or fat, when elevated they can be a sign of prediabetes. High sugar and carbs intake can impact cholesterol levels. HbA1c: This measure captures a 2–3-month average blood sugar level and is used to assess risk for developing type 2 diabetes. Fasting insulin and fasting glucose: these measures can be used to calculate HOMA-IR, a measure of how well your cells are responding to insulin. What to do to support our metabolic health Supporting our metabolic health is just like training a muscle. It is the consistent things we do every day that add up to the overall picture of metabolic health. Supporting our metabolic health involves making smart dietary choices, getting adequate sleep, managing stress, engaging in physical activity, and reducing exposure to environmental toxins. Reduce intake of refined carbohydrates: these can quickly spike blood sugar and insulin levels, leading to a crash later in the day. Pair carbohydrates with proteins, fats, and fiber to reduce glucose spike: Always combine starches with protein, fat, and fiber to help maintain a level blood sugar. If you plan to eat something sugary, have it after your meal instead of on an empty stomach to lower the glucose spike. Eat fiber-rich foods: Fiber helps slow the breakdown of glucose into the bloodstream. Fibers also help feed the beneficial microbes that live in the gut. Supporting the gut microbiome can help improve insulin sensitivity and our response to glucose-rich foods. Engage in regular exercise: Exercise can help regulate our blood sugar levels and improve our insulin response. Aim for 150 minutes per week or 30 minutes on most days. Even taking a 10–15-minute brisk walk after meals have been found to help regulate blood sugar levels. Get 7-8 hours of adequate sleep per night: Sleep can also play a role in our metabolic health. Poor sleep can lead to less clearance of glucose from our blood stream and higher insulin levels. When we don’t get good sleep, we may be more likely to make poor dietary choices and crave simple carbohydrates. Meditation and Stress management: Stress can also impair our metabolism and throw off our insulin levels. When we are stressed, we produce more of the hormone cortisol. Cortisol can attract glucose stored in the muscles and liver into the bloodstream, increasing blood glucose levels. It also shuts off insulin production. As a result, we have more sugar floating in the bloodstream. Meditation is a great way to help reduce your overall stress.
Mar 29, 2022
5 min read

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