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Christine Chung
You’ve just found a new, fleshy growth around your genitals... could this be HPV?
Certain strains of the Human Papillomavirus (HPV) can cause lesions or warts in the genital area. These growths can be alarming. You may be wondering - what are these growths? Am I going to have them forever? How can I make them go away?
We know it can be a scary experience and it’s difficult to know exactly what to do. Rest assured we are here to provide all the necessary information as well as measures you can take to relieve your symptoms. We are also here to reassure you that the condition is harmless and will likely go away with time.
First, it is important to understand whether you have genital warts or something else.
What are Genital Warts?
Genital warts typically occur on the genital areas anywhere from a few weeks to 2-3 months after contracting an HPV infection.
Genital warts tend to be soft, fleshy, cauliflower-like growths that can grow in areas including the vulva, vagina, anus, scrotum, and penis. The warts can be itchy, annoying, and persistent, but are rarely painful.
Genital warts are often skin-colored or appear as white bumps. They may grow as a single wart or in a bunch.
Genital Warts Are A Difficult Thing To Discuss
How are they Transmitted?
Genital warts are easily transmitted through skin-to-skin contact, commonly through sexual interactions. This includes vaginal, anal, and oral sex, as well as hand contact. It can take several weeks, months, or even years for genital warts to appear once you’ve been infected.
You may never show symptoms. Even without symptoms like visible warts, you can transmit HPV to your sexual partner.
Though rare, genital warts can also be passed during childbirth as a child passes through the mother’s birth canal.
Genital Warts and the HPV Virus are Easily Transmitted During Sex
How do I get checked?
If you suspect you might have warts around your genitals or anus, seek advice from a medical professional, nurse or a medical doctor. Other STIs such as herpes or syphilis can also present similarly to genital warts and may need to be treated. What you’re seeing could also just be a mole, ingrown hair, hemorrhoid, or skin tag, all of which are relatively harmless.
Generally, if the symptom is new and you are concerned, we recommend getting a professional opinion.
How is HPV Related?
All warts, including genital warts, are caused by strains of the HPV family. Warts found on your genitals are caused by a different strain than the ones on other parts of your body, like your hands or feet.
HPV is one of the most common viruses that affect humans. HPV is considered the most common sexually transmitted infection in the United States. HPV affects millions of men and women every year. The Center for Disease Control and Prevention estimates that almost every sexually active adult will get HPV at some point in their lifetime.
However, HPV is also responsible for other non-sexually transmitted infections like plantar and common warts. Warts that cause infection on your hands and feet do not cause infection on the genitals.
High and low-risk HPV strains
Out of the numerous strains of HPV, we have identified those that are high-risk and low-risk to our health. High-risk strains can cause cervical, oral, and anal cancer.
The strains that cause genital and other warts are considered low-risk HPV strains and are very unlikely to cause cancer. These low-risk strains that cause genital warts will often be eliminated by the immune system within a few weeks to months with no significant complications.
Can I still catch other strains of HPV?
It is possible to be infected by multiple strains of HPV. Having warts from a low-risk strain of HPV does not mean you are not at risk of contracting more high-risk HPV strains that can cause cancer. For this reason, we recommend following your physician’s Pap screening recommendations and being tested regularly.
What Can I do Naturally?
Most HPV infections and related complications, like genital warts, can be cleared by a strong, healthy immune system. Your immune system can be optimally supported in a number of natural ways:
Eat plenty of fruits and vegetables: A healthy diet provides the foundation to the immune system. Food promotes gut health, supply’s the body with antioxidants, amino acids, and other compounds that form immune molecules. Conversely, a poor diet can cause inflammation and take energy away from the immune system and impair its function.
Quit smoking: Several studies have found a link between cigarette smoke and increased risk for HPV infections, including genital warts. Quitting smoking is the first step to supporting our overall health.
Reduce alcohol consumption: Alcohol can impair bodily processes, especially the liver and detoxification pathways. Cut down to 1-2 servings once or twice a week to promote health.
Drink or supplement green tea: the powerful antioxidants found in green tea extract have been found to reduce HPV persistence, as well as genital warts.
Get in regular movement and exercise: exercise and movement help promote circulation and support the immune system. We recommend at least 20-30 minutes of light aerobic walking or cycling each day and 2-3 sessions of resistance training.
Papillex, is a clinically-researched, nutrient-rich supplement designed to increase your body’s ability to respond to HPV naturally.
By optimizing your natural immunity and replacing missing and low nutrients, Papillex helps you to create an environment inhospitable to HPV and its common symptoms including cervical dysplasia and genital warts.
Sep 30, 2019
4 min read
Christine Chung
Cervical cancer is the eighth most common cancer in the world and the fourth most frequently diagnosed cancer in women, with over 570,000 new cases in 2018, as stated by the World Health Organization.
In this article, we aim to clear up any confusion about HPV, cervical cancer, and how the two are related by answering the following questions:
How does it happen?
What are the symptoms?
How is Human Papillomavirus related to cervical cancer?
Could you be at risk?
What is Cervical Cancer?
Cervical cancer occurs when a cervical cell changes or behaves abnormally, forms cancer cells and then grows into nearby tissue.
As with other cancers, the biggest danger can be the spread to other parts of your body.
The cervix is part of your reproductive system, and as you may have guessed, is where cervical cancer occurs. It’s the narrow end of your uterus that opens out to your vagina - think of it as a tunnel from your vagina to your uterus.
Types of Cervical Cancer
The type of cervical cancer is dependent on which cells have become affected:
Squamous Cell Carcinoma (70-90% of cervical cancer cases) - the cells affected are the flat, skin-like cells that cover the outer surface of the cervix, known as squamous cells.
Adenocarcinoma ( ≈ 10% of cervical cancer cases) - making up the majority of alternative cervical cancer types, adenocarcinoma affects the glandular cells in the passage between the cervix and the womb.
Adenosquamous Carcinoma (a minority of cases) - this rare cervical cancer affects both the squamous and glandular cells of the cervix.
Small Cell Cancer (very rare aggressive form of cervical cancer) - small cell cancer is the rarest of the four listed here and is more likely to spread quickly to other areas of the body, such as lymph nodes.
What Are The Symptoms?
Abnormal vaginal bleeding (between periods, after intercourse)
Increased vaginal discharge, especially with foul smell
Heavy or long periods
Painful intercourse
Loss of appetite
Weight loss
Fatigue
Do ALL Cervical Cell Changes Cause Cancer?
Simply, no.
Sometimes cells can change but stop growing or acting abnormally, in which case there can be benign (non-cancerous) growths such as fibroids. These growths can also cause pre-cancerous growths, meaning they are acting abnormally but they are not cancerous yet.
These can be detected by routine Pap Smear Tests and is one of the reason why they are so important.
What is a Pap Smear?
A Pap smear is a screening procedure involving the collection of a small sample of cells from your cervix.
Your doctor will use a speculum inserted in your vagina and a small brush to collect a sample which is then sent off for testing.
Pap smears may be a little uncomfortable, but with proper technique, they should not be painful.
Why Get a Pap?
Prevention is key in cervical cancer.
Cervical cancer is a slowly developing form of the disease that can take years to become fully-fledged cancer.
For the most common form of cervical cancer - squamous cell carcinoma - the individual starts developing abnormal cells that then become more and more affected.
The levels of cell abnormality are graded by the terms CIN I, II, and III, ASC-US, LSIL and HSIL, before being classified as cancer. These terms may be confusing, but can simply be thought of as technical medical terms which help you and medical professionals understand at what stage of abnormality your cells have become.
It can take your body years to progress through these stages.
Regular pap smears allow for your healthcare provider to track the progression of abnormal cell growth to inform the optimal treatment plan.
How is HPV Related?
Human Papillomavirus is one of the most common viruses that affect the world population, being the most sexually transmitted infection in the United States.
HPV affects millions of men and women every year.
The Center for Disease Control and Prevention estimates that almost every sexually active adult will get HPV at some point in their lifetime. It can be spread by skin to skin contact, most commonly through sexual activity.
In most cases, HPV is found to be the cause of cervical cells acting abnormally.
How does it become Cervical Cancer?
Not all HPV infections will cause cancer.
In fact, only a few out of the known 100+ strains of HPV can lead to cancer.
Most of the time, with a robust immune system, your body is able to clear these infections without any symptoms!
When we have a weakened immune system however, or when our bodies are invaded by a strong strain of HPV, cell proliferation - the rapid increase in abnormal cervical cells - can occur.
This can lead to cervical intraepithelial neoplasia (CIN), one of the grading systems mentioned before in this article, which over a number of years can lead to more abnormal cells and eventually cancer.
Sep 30, 2019
4 min read
HPV Strains: The Ultimate Guide
Dr Elizabeth Goldspink
The majority of cervical cancer cases come from two particular types of HPV: HPV 16 and 18.
Viruses are all around us and can be contracted in any number of different ways. They vary from the common cold to hepatitis to HPV.
HPV is contracted from skin-to-skin contact, usually during sexual intercourse, and different strains can potentially lead to genital warts, cervical dysplasia or, eventually and in the very worst case, cancer.
It can be overwhelming to know what to pay attention to and when to elevate your concern in discussing HPV strains. Especially as there are upwards of 100 different strains of the virus.
These strains are not all of the same risk in terms of potential symptoms developing from them, the majority are low risk strains with most people possibly having the virus and never seeing any untoward effects from it.
There are, however, higher risk strains too. In fact, many high-risk strains are also symptom-less up until the point at which they cause serious health problems, like cervical cancer.
We want to make this easy for you to understand, and also to know what moves to make, if you end up being affected.
Understanding the HPV Picture
Before we get into the types of strains it’s important to remember that infection with HPV is very common.
The Centers for Disease Control and Prevention estimates that there are 6.2 million new infections each year in the United States. Nearly all sexually active men and women will have had a type of HPV infection at some point in their lives.
Most people go about life symptomless, but in some men and women, the infection persists.
The goal of Papillex is to help to improve the body’s immune response and correct nutritional deficiencies that can contribute to persistent HPV infections. Our naturopathic doctors have created this product out of a need to help people respond to HPV infections naturally using an evidence-based approach.
How Is It Passed On?
Transmission of HPV occurs through sexual skin-to-skin contact.
While it is most commonly spread through vaginal or anal sex, it can also be spread through oral sex.
The Centers for Disease Control and Prevention estimates that there are 6.2 million new infections each year in the United States. Nearly all sexually active men and women will have had a type of HPV infection at some point in their lives.
In most people, the immune system is able to clear the infection on its own in a short time, so they pass it on unknowingly with no signs or symptoms.
What About the HPV Vaccine?
As higher risk HPV type 16 and 18 are known to cause 70% of cervical cancers; three HPV vaccinations have been developed to help mitigate this virus. All three of the vaccinations available protects against HPV type 16 and 18.
Two of the vaccines also protect against HPV types 6 and 11, which cause anogenital warts, while the third protect against three other higher risk strains of HPV that cause 20% of cervical cancers.
While these vaccines are not meant to treat HPV infections or associated symptoms and diseases, such as cervical cancer, they care very effective in prevention. These vaccines have been proven with clinical trials to be safe and effective in preventing HPV infections.
Men and women have been approved for the vaccination, with a World Health Organization recommendation for girls aged 9 to 14 to receive the vaccine. Some countries have begun approval for boys of this age to be equally vaccinated to prevent transmission.
As the vaccine is not useful for treatment, prevention is optimal at an age before sexual activity.
The Strains
HPV 2 and 4: The types of HPV virus strains that many have experienced are strains 2 and 4, responsible for the “common wart.” These are the kind of warts that often occur on our hands or feet that are easily treated at your medical doctor’s office or with simple over the counter products.
The more concerning, higher risk types of HPV are sexually transmitted. There are approximately 40 of those strains; four of these strains are the most concerning because of their ability to cause genital warts and cervical cancer.
Here’s the breakdown on those 4 types:
HPV Types 6 and 11
6 and 11 are the most common cause of genital warts, and account for approximately 90% of HPV genital wart infections. These strains are rarely associated with cancer. Warts may appear within several weeks after sexual or intimate skin to skin with someone who is infected with HPV type 6 or 11.
HPV Types 16 and 18
These are called high risk because they can cause cancer in both men and women. Most cases of cervical cancer come from these two particular strains; these strains can also lead to throat cancer, anal cancer, penile cancer, or cervical cancer.
How Will I Know If I Have HPV?
Receiving routine pap smears is the best way to be proactive about HPV.
Most women do not ever reach the stage of cervical cancer through HPV infections, as cell progression is caught easily in pap tests, and preventative measures can be taken.
The recommendation for disease control and prevention is to get one pap test every three years to keep an eye on your cervical cells, and more frequently if you have ever had an abnormal pap test.
It can be frustrating looking for answers
Some doctors will recommend getting a pap smear once a year through their experience of seeing patients testing positive following a pap one year ago.
Other professionals have even recommended getting anal pap smears or anoscopies to screen for anal cancer, as anal cancer from HPV will not show up with changes in cervical cells.
This is a highly recommended option for sexually active males who have anal sex.
What if I Test Positive for HPV 16 or 18?
Testing positive on HPV tests for types 16 or 18 doesn’t mean that you will develop cervical cancer, but it does mean that any dysplasia found on a pap test carries a higher risk of becoming cancerous.
If you test positive for a higher risk strain, your doctor may take a “wait and see” approach and simply suggest more frequent pap tests, because your body may clear the infection on its own.
This approach is safe – it can sometimes take 15 to 20 years for high risk HPV types to cause cervical cancer.
If your pap test shows more severe abnormalities, there are additional measures that your doctor can take to prevent cancer from developing, including LEEP, cryotherapy, or photodynamic therapy.
here are many scenarios where high risk HPV does not progress into cervical cancer, and your healthcare provider can help you find the approach that’s right for you.
What Can I Do While I “Watch and Wait”?
Begin making lifestyle changes right away to prevent further progression!
This is as easy as changing your diet, exercising, sleeping well, decreasing stress, cutting out smoking, excessive alcohol consumption, and other toxic components of your life.
This will all help to support your body and immune system in fighting an HPV infection before it gets worse.
Making good lifestyle changes can help your body respond to infections like HPV
Papillex is a nutrient-rich supplement designed to optimize your immune system’s response to HPV.
Positively diagnosed people with weakened immune systems are more susceptible to developing cervical cancer, shortening the 15 to 20-year margin down to 5 to 10 years.
By optimizing your natural immunity and replacing missing and low nutrients, Papillex helps you to create an inhospitable environment for HPV to live.
Find out more about the Papillex 60 Capsule Bottle and how it works!
Our recommendation is: Why watch and wait, when you can be proactive? Read our blog for ways that you can be proactive now through diet, lifestyle and targeted supplementation.
Sep 17, 2019
6 min read
Dr Elizabeth Goldspink
Cervical cancer is the fourth most frequently diagnosed cancer in women, as stated by the World Health Organization to account for 6.6% of cancers in women.
Cervical cancer has a very good prognosis if it is caught early. The best treatment in the case of cervical cancer is prevention.
Prevention, routine screening, early diagnosis, and appropriate treatment makes cervical cancer very manageable.
Being proactive with your health, in all aspects, is essential for optimal prevention. Keep on reading below to know everything about HPV testing, and how you can be proactive with your health.
What is HPV?
Human Papilloma Virus, or HPV, is a common virus that affects humans, being claimed by the Centers for Disease Control and Prevention as the most sexually transmitted infection in the United States.
It affects millions of men and women every year. In fact, it is so common that the CDC estimates that HPV will be contracted by almost every sexually active adult in their lifetime.
Transmission
HPV can be spread by skin to skin contact, most commonly through sexual activity. Although some people may not be aware of this, but it includes oral and anal sex.
How Does It Become Cervical Cancer?
Although not all HPV infections will cause cervical cancer, the rates of cervical cancer increase every year. Among the hundreds of HPV strains that have been identified, only a handful are likely to cause cervical cancer.
Like any other virus, your body should be able to fight off HPV when you come into contact with it. However, when your immune system is down for the count, that’s when HPV can proliferate and cause growth of abnormal cervical cells, cervical dysplasia, and eventually, growth of cancerous cells.
Pap Smears and HPV Tests
The Pap Smear is the recommended test that should be routinely performed by a trusted medical professional to screen for the potential of cervical cancer progression.
What is a Pap Smear?
A Pap smear collects a small sample of cervical cells using a small brush. Your doctor will insert a speculum into your vagina in order to get an accurate sample from your cervix. This step may be a little uncomfortable, but should be relatively painless.
How Often Should I Get a Pap?
The United States Preventative Services Task Force (USPSTF) recommends sexually active women between the ages of 21 to 65 to receive routine Pap smears every 3 years. Women between the ages of 30 and 65 can choose to prolong their screening exams to every 5 years, paired with an HPV test.
What is an HPV Test?
The HPV test is different from routine Pap screenings. Pap smears test your cervical cells to see if they are cancerous or potentially on their way to being cancerous. The HPV test cannot tell you the status of your cervical cells. It will test for the presence of HPV in your body, typically high risk HPV.
Testing for high risk HPV will test for specific strains of HPV, like HPV 16 and HPV 18 that are associated with high risk for cervical cancer progression.
The HPV test is usually recommended if your Pap repeatedly shows abnormal results, or if you are over the age of 30 and wish to spread out your routine Paps.
The result of the HPV test will usually help your doctor decide when to begin treatments that may be more invasive.
Natural, Proactive Steps
If you have abnormal cell growth detected on your Pap smear, your medical doctor is very unlikely to begin treatment. Most HPV infections are easily cleared by a strong, healthy immune system. Your immune system can be supported in a number of natural ways:
Eat plenty of fruits and vegetables
Quit smoking
Reduce alcohol consumption
Drink green tea
Exercise to sweat
Aug 28, 2019
3 min read
Christine Chung
Most people know that HPV is spread through skin to skin contact during sexual activity involving the genital area.
Although, it is most commonly transmitted through vaginal sex, did you also know that it can also be spread through anal and oral sex too?
In the following article, we aim to answer all the questions you have about HPV infections, dispelling some of those myths which could leave you more vulnerable.
Common HPV Infection Questions
I only have one sexual partner, does this mean I won't get HPV?
Even being sexually active with only one person can bring on an HPV infection. Having more sexual partners will put you at higher risk for contracting an HPV infection.
I won’t be at risk because my partner didn’t have any symptoms…right?
The short answer is: you could still be at risk.
Unfortunately, HPV can be passed on even when someone with an HPV infection does not have any symptoms.
With a healthy immune system, someone may suppress symptoms of the HPV infection, but the virus can still hop over to another host. With a healthy immune system, chances are it won’t cause any serious complications.
Lots of questions arise when talking about HPV. Hopefully we can answer some of them for you :)
We use physical protection (i.e. condoms) every time so I’m safe.
While condoms provide excellent protection against sexually transmitted infections, they only provide some protection against HPV.
Condoms do not cover the entire genital area, so you can still get the HPV virus though skin to skin contact in the genital area even if you’re wearing a condom. It can also be spread through contact with other areas that aren’t covered.
In other words, you can get HPV through oral-genital or hand-genital contact – not just sexual intercourse!
If I got it once, I’m safe now…right?
You can be infected with HPV more than once, even if you’ve already been exposed to HPV before.
It is possible that the body may not have developed long-term protection against the virus, or you may come into contact with a completely different strain of the virus, remembering that there are over 100 different types of HPV.
What serious conditions can develop from having HPV?
The following conditions can all stem from having a particular strain of HPV:
Genital warts
Cervical dysplasia
Precancerous lesions
Cervical cancer
HPV Detection and Prevention
HPV testing is key to detecting and thus preventing further high risk complications of HPV in women.
A good way of doing this is to attend routine women’s health screening exams with your medical doctor.
Pap Smear Test
These are usually done once every 3 years after the age of 21 in sexually active females.
The Pap Test detects even the earliest cellular dysplastic changes and this timely detection has led to reduction in the progression to cancers.
A Pap test must be repeated every one to two years after the first Pap test. An abnormal Pap smear will be followed up with further testing to detect the stage of abnormality.
It could just be abnormal cell growth with no cancerous disposition, or it could be a growth of squamous cells, which are likely to result in cancer.
HPV Test
It is important to note that the FDA has approved the HPV test to be used for women over 30 years old, as it may be useful in finding HPV before there are cervical changes.
There are now very accessible HPV tests kits that you can use from the comfort of your own home.
These are quick and easy to use, detecting the highest risk types of HPV, 16 and 18, as well as multiple other strains that may cause health problems. Some popular, high-accuracy kits are listed below:
https://evekit.com/
https://www.nurx.com/
https://www.letsgetchecked.com/ca/en/
https://www.everlywell.com/products/hpv-test-female/
In the United Kingdom, they are now sending at-home HPV testing kits in the mail for free to decrease the number of women who have further progressing HPV complications.
HPV Treatment
HPV treatment is often sought, and although there is no cure for HPV, there are many treatment therapies available for symptoms of genital warts and cervical dysplasia. These include cryotherapy, LEEP, surgical removal, laser surgery, or photodynamic therapy.
There are also several clinical trials outlining the success of each therapy.
What can I do naturally?
Although there is no cure, most HPV infections
are easily cleared by a strong, healthy immune system. Your immune system can
be supported in a number of natural ways:
Eat plenty of fruits and vegetables
Quit smoking
Reduce alcohol consumption
Drink green tea
Exercise to sweat
Papillex has been designed with HPV sufferers in mind. It is a clinically-researched, nutrient-rich supplement designed to increase your body’s ability to respond to HPV naturally.
Aug 14, 2019
4 min read
Christine Chung
What is Folic Acid?
Folate is a member of the B vitamin (B9) family, a water-soluble vitamin involved in many chemical processes in the body. Folic acid is the synthetic form of folate.
Folate is essential for the production of red and white blood cells and other important cells that help to convert food into energy and make DNA. Folate also plays an important role in the reproductive tract and is needed to maintain a healthy pregnancy.
The body cannot create folate on its own so we must obtain it through our diet or supplementation. Research on HPV has begun to highlight a strong association between folate deficiency and cervical dysplasia, emphasizing the importance of incorporating more folate-rich foods into your diet as well as taking a quality supplement.
Folate versus Folic Acid
Folate differs from folic acid in the way that the vitamin gets converted in the digestive tract. Folate is immediately converted into the active form of vitamin B9, called 5-methyl-THF (5-MTHF). Folic Acid enters the bloodstream and passes through the liver and other tissues in order to be converted.
Folic acid is thought to be better absorbed, however, it is metabolized at a slower rate, which means more can accumulate and linger in the system and may lead to excess. Folate, on the other hand, will be excreted if too much is consumed.
Folate Deficiency
Folate plays a critical role in your body so when it is lacking, it can lead to suboptimal health but it isn’t always easy to know when you are low in vitamin B9. Some symptoms include unexplained fatigue, anemia, muscle weakness, shortness of breath, difficulty focusing, brain fog, headaches, and heart palpitations.
Deficiencies in folate can cause megaloblastic anemia, which is when your blood cells form in an improper shape. This hinders their ability to function correctly in your body. Folate is especially important for pregnant women, as deficiencies can cause neural tube defects in a growing fetus.
Folate and Methylation
Without folate, the body has trouble maintaining methylation. Methylation is a biochemical process that helps support cardiovascular, neurological, and reproductive health.
The cycle of methylation begins with a methyl group (one carbon and three hydrogen molecules) converting amino acid, methionine into S’Adenosylmethionine (SAM-e). Once converted into SAM-e, this molecule travels through the body transferring methyl groups to other bodily systems. SAM-e Is finally converted to the amino acid homocysteine, which creates the antioxidant glutathione.
A deficiency in folate or B12 impairs the final stage of methylation, leading to elevated levels of homocysteine. Too much homocysteine increases the risk of heart disease and blood clots.
Methylation also regulates our genes, turning them on or off. One of the ways cancer develops is through impaired gene regulation. Not having enough folate can impair the body’s ability to regulate cell growth and increase susceptibility to cervical cancer.
MTHFR Gene Mutations
Some people have a genetic mutation that prevents them from properly converting dietary folate into its active form (5-MTHF). This mutation may explain why women with healthy diets and lifestyles struggle to clear the infection, while others who smoke and eat poorly can eliminate the infection with no problem.
Individuals with the MTHFR mutation have an increased risk of several diseases including heart disease, colon cancer, and breast cancer. Supplementing with the active form of folate (folic acid or methylated folate) can be beneficial for those with the mutation.
Methylation is also impacted by diet in general. Studies have found the degree of methylation in the body to correlate with the volume of fruit and vegetables participants consumed. The findings suggest that dietary modifications to include more folate in the diet can reduce the risk of cervical dysplasia.
Benefits of Folic Acid
The average adult is recommended to take 400mcg of folate daily. Although folate is best known for preventing neural tube defects in fetuses, new research is showing its benefits in cancer prevention including breast, bladder, cervical, ovarian, and pancreatic cancers.
Because folate is involved in reducing homocysteine, folate intake can influence heart disease. Recent research is showing benefits in reducing the risk of Autism Spectrum Disorder, Dementia and Alzheimer’s, and depression.
Food Sources of Folate
We recommend aiming for your daily dose of folate from food, before supplementing. Food sources of folate include:
Dark green leafy vegetables (i.e. kale, spinach),
Broccoli,
Black-eyed peas,
Liver,
Asparagus,
Brussels sprouts,
Avocado,
Broccoli,
Green peas,
Fortified Grains*.
*Because of the utmost importance of folate adequacy, the Canadian government, along with other governments have mandated folate fortification to many grains, like breakfast cereals, white flour, and pastas.
Folic Acid’s Role in HPV Management
Folate is one of several key nutrients that have been studied in relation to HPV.
Folate’s role in HPV is likely related to the methylation cycle mentioned above, which ensures your genes function normally.
Current research has highlighted the relationship between low levels of folate in the blood and high-risk HPV infection through the promotion of cervical dysplasia development.
Studies have found that individuals with a folate deficiency have an increased risk of positive HPV status, as well as an increased risk of progression to cervical and oral cancer. Whereas women with higher plasma folate and B12 levels with HPV-16 positivity were 60-75% less likely to be diagnosed with moderate cervical dysplasia.
There has been extensive research on the role of folate in HPV. We highlighted some key research below:
A 2003 study by Hernandez et al. showed that women with the highest levels of blood folate levels from either food or supplements have lower rates of cervical dysplasia from HPV.
A 2016 case-control study by Zhao et al. that included 271 controls and 214 women with both high and low-grade HPV lesions, found that low blood folate levels in women were coupled with a higher risk of cervical cancer from HPV.
A large analysis of studies, or a meta-analysis, showed an increased risk of cervical cancer among Asian populations with low blood folate levels.
A study by Bai et al. showed that a folate deficiency was associated with an increased risk of squamous cell carcinoma of the cervix and cervical intraepithelial neoplasia (CIN) in subjects who were HPV 16 positive.
In an Indian population, improving folate and vitamin B12 status may have a beneficial impact on the prevention of cervical cancer.
Scientific evidence shows that folic acid likely plays a protective role in HPV progression to cervical cancer.
Folate is one of the many key protective nutrients in Papillex. A daily serving of Papillex contains the equivalent of 5 ounces of poultry liver, 4 cups of chickpeas, or 40 spears of asparagus.
Should I Supplement Folic Acid?
It is estimated that 5 to 40 percent of the female population has a folate deficiency globally.
Ideally, we would obtain our folate from food sources like dark leafy greens, vegetables, fruits, nuts, and seafood. However, it can be difficult to get the recommended amount of folate from food alone. As mentioned, a person’s genetics may also make it difficult to convert dietary folate into its active form.
Folic acid supplementation of 400mcg per day is safe. The highest level of daily intake of folate that poses no risk of adverse health effects was set at 1,000 micrograms per day. Folic acid is also a water-soluble vitamin and does not accumulate in fat tissue. Therefore, excess intake will be excreted into the urine and out of the body.
Supplementation with folic acid is often recommended for pregnant women to prevent neural tube defects and prevent megaloblastic anemia.
Supporting HPV Naturally
Many doctors choose to implore a “watch and wait” tactic, as it is difficult to begin treatment without further progression of abnormal cells. Some people wait years before seeing this progression, and most surgical interventions do not have an immense effect on the early stages of cell changes.
Even if you eat the healthiest possible diet, you may still have several nutritional deficiencies which can harm the health of your immune system. This is why in addition to a diet high in richly pigmented fruits and vegetables, it’s important to supplement your diet with clinically supported nutritional supplements.
Papillex is a compound that contains high-quality, natural sources of nutrients that have been shown to support beneficial results in eliminating HPV infections. It contains ingredients that nutritionally support the immune system which will help the body to better respond to genital warts, cervical dysplasia, and other HPV-related disorders naturally.
Aug 07, 2019
6 min read
HPV and Pregnancy: The Ins and Outs of Having HPV While Pregnant
Christine Chung
The number of people with positive HPV diagnoses is climbing every year. Millions of Americans are newly diagnosed with HPV and are unaware of the potential consequences. HPV is now the most common sexually transmitted infection.
The Center of Disease Control now estimates that nearly everyone who is sexually active will have contracted a strain of HPV at some point in their lives.
The good news is, most strains will be cleared by your immune system and will not cause any health concerns.
There are a few strains that may cause genital warts and some high-risk strains of HPV that have the potential to cause cervical cancer. This growing concern is a high concern for pregnant women, or those considering pregnancy in the near future.
What can you do if you plan on getting pregnant?
Get regular pap tests.
High-risk types of HPV have been known to cause cervical cancer. This is a serious complication in fertility and pregnancy. Most women do not ever reach the stage of cervical cancer, as cell progression is caught easily in pap tests, and preventative measures can be taken. The recommendation for disease control and prevention is to get one pap test every three years to keep an eye on your cervical cells, and more frequently if you have ever had an abnormal pap test.
Papillex is not recommended for pregnancy due to the mixed carotenoids in the ingredient formula. While beta-carotene, great against HPV, has not been associated with any complications in pregnancy, high doses of vitamin A have been.
It is always important to consult your healthcare practitioner when taking any new supplements, especially if you are pregnant.
However, Papillex may be a great supplement for you prior to pregnancy. It will help keep your immune system robust, fighting the HPV infection. This will bar any complications of HPV starting off in your pregnancy.
What can you do if you’re already pregnant?
Pregnant women are screened according to the current guidelines.
Being pregnant does not change the amount of pap tests you get; meaning you’re still allocated to one pap test every three years. If you have not had any abnormal cell findings in your past pap tests, you are likely to be in the clear until your pregnancy is complete.
Most
pregnancies continue to full-term with
no complications and babies are born with no signs of being carried by
someone with an HPV infection.
What are the risks?
With high-risk strains of HPV infection, HPV-16 and HPV-18, abnormal cervical cells can progress to cervical intraepithelial neoplasia. If you have ever gotten this diagnosis, you probably know if it is a CIN 1, 2, or 3.
CIN 1 is the least concerning, and CIN 3 is the most concerning and most likely to progress into cervical cancer. When an HPV infection causes CIN damage to the cervical cells, these lesions have been associated with premature labour and low birth weight in some cases.
There is a very low risk of transmission of the pregnant woman’s HPV infection to the child. One study followed 153 pregnant women through their pregnancies, some of which had previous HPV infections, and some with newly diagnosed HPV diagnoses through their pregnancies.
HPV DNA was detected at birth in 5.2% of the babies born to healthy women and was associated with the detection of HPV DNA in the mothers during any given trimester.
To add: just because the child has HPV DNA, does not mean that they will get cervical cancer, or even show any symptoms throughout their life.
In
the worst case scenario, the HPV strains causing genital warts may cause respiratory papillomatosis in the baby,
which is the development of warts in the baby’s throat, which must be removed
surgically.
If you have a high-risk strain and must pursue treatment throughout your pregnancy, check out our blog post on HPV and Photodynamic Therapy to get the low-down on this potential option to treat warts and abnormal cervical tissue.
What else can you do as a pregnant woman with HPV?
Most doctors will recommend a “watch-and-wait” protocol and may have some other suggestions with therapies for pregnant women.
The bottom line is, the earlier you catch any abnormal cell changes, the better. Starting treatment right away is a preventative measure to stop further progression.
This is as easy as making lifestyle changes, eating better, exercising, sleeping well, keeping your stress levels low, cutting out smoking, alcohol consumption, and other toxic components of your life.
This will all help to support your body through your pregnancy, and keep your HPV infection at bay while growing another human!
Why watch and wait, when you can be proactive? Order Papillex today!
Jul 01, 2019
4 min read
Christine Chung
About 80 % of women around the world get HPV. What is the treatment?
The Low Down On HPV
The number of people with HPV are rising every year. Wondering if you could be at risk? Read below to learn about the climbing risks of HPV.
What Is HPV?
Human Papillomavirus is one of the most common viruses that affects humans, being the most sexually transmitted infection in the United States. HPV infection affects millions of men and women every year.
The Center for Disease Control and Prevention estimates that almost every sexually active adult will get HPV at some point in their lifetime. It can be spread by skin to skin contact, most commonly through sexual activity. Vaginal, oral, and anal sex can lead to the transmission of HPV.
Should You Be Worried?
There are low risk and high risk types of HPV.
Most HPV infections are self-limiting and usually resolve within a period of 1-2 years. The person may not even be aware that they had contracted an infection with a robust immune system.
Like any other virus, your immune system will be able to clear HPV pretty easily. There are, however, a few high risk strains that can be responsible for some health concerns in women, such as the following clinical conditions:
Genital warts
Cervical dysplasia
Precancerous lesions
Cervical cancer
Genital Warts
Genital warts appear as papules near vagina, cervix, vulva, or anus.
These warts are visible to the naked eye and can be easily detected by a visual examination. They are itchy, painless, pink papules and may appear as cauliflower-like growths, termed condyloma acuminatum. The growths could be flat or raised and can appear as single growths or even in groups.
Cervical Dysplasia
Cervical dysplasia is an abnormal cell growth that is commonly precancerous, on the surface lining of the cervix or the opening between the uterus and the vagina. You may see this in your pap smear results as Cervical Intraepithelial Neoplasia (CIN).
Precancerous Lesions
Precancerous lesions may also occur in the female genital tract. These may become cancerous as the cell abnormalities continue to increase.
Cervical Cancer
Cervical Cancer and HPV are synonymous together, given that it is the most common cancer due to HPV.
It is caused by 2 high-risk types of HPV, HPV 16 and 18 that cause 70% of cervical cancers and precancerous lesions.
Don't panic! By following your doctor’s medical advice, attending regular checkups, and keeping your immune system strong, the chance of your HPV leading to cancer is unlikely.
Testing is an important element of any successful prevention strategy when it comes to HPV and its complications.
Prevention
In terms of prevention through sexual activity, condoms are the best physical method of prevention, but they do not prevent HPV completely because there are still some exposed genital areas that may come into contact.
Being sexually monogamous with a monogamous partner is also a good way to increase prevention.
Vaccinations
There are multiple HPV vaccinations available that are FDA approved to prevent diseases caused by HPV. It is recommended to get before the age of 25. There are now school-based HPV vaccination programs offered to boys and girls around grades 7 and 8, prior to the onset of sexual activity to optimize prevention strategies.
It is also most optimal at this stage as vaccines are more effective with a young teen immune system. There are 2 or 3 vaccinations over a 6 to 12-month period to receive full immunization.
Is There a Cure?
There is currently no cure for the virus available.
There are many treatment therapies available for symptoms of genital warts and cervical dysplasia, such as cryotherapy, LEEP, surgical removal, laser surgery, or photodynamic therapy.
There are many clinical trials outlining the success of each therapy – they are discussed in further detail in our other blogs, so go check them out for more learning!
What Can I Do Without Treatment?
Although there is no cure, most HPV infections are easily cleared by a strong healthy immune system. Your immune system can be supported in a number of natural ways:
Eat plenty of fruits and vegetables
Quit smoking
Reduce alcohol consumption
Drink green tea
Exercise to sweat
A healthy diet is key to helping your body fight off infection
Papillex, is a compound that contains high quality, phytoceutical nutrients that have been shown to support beneficial results with respect to HPV.
It is packed full of ingredients that nutritionally support the immune system, helping the body to better respond to genital warts, cervical dysplasia, and other HPV-related disorders naturally.
Jul 01, 2019
3 min read
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