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AHCC®

AHCC® is a patented shiitake mushroom extract for bolstering the immune system. Backed by over 30 Human Clinical Studies, it’s proven science for real results.

Clear
  • One of the best researched nutritional supplements in the world
  • Stimulates immune response to promote health and wellness*
  • Supports Natural Killer Cell (NK) activity*
  • Used for centuries in traditional practice
  • Can be taken as a top up or for ongoing immune support

Pure and simple AHCC®

  • No fillers, vegan capsule 
  • High quality sourcing
  • Verified as authentic by 3rd Party Lab
  • Meets or exceeds FDA & Health Canada Standards
  • 60 capsules per bottle 
  • Generally, a serving of 1-3 grams daily is recommended for immune support. Higher servings may be taken to support the immune system in response to more specific conditions. Or as directed by your health practitioner. 
  • AHCC® can be taken with Papillex® synergistically to support the body’s response to HPV. For HPV, clinical trials have shown benefit with 3g of AHCC daily (2 capsules three times a day or 3 capsules twice a day).
  • If swallowing or taking supplements is a challenge, AHCC® may also be taken with food.
  • Consistency is the foundation to better results that last. Some results may be felt immediately but allow your body approximately 3 months to experience the full benefits.

Advanced Immune Support, Sourced with Integrity

Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free

High Quality Immune Support

Support your Innate Immune System*
AHCC® contains polysaccharide compounds called alpha-glucans and beta-glucans. They help promote the innate immune system by supporting the activity of natural killer cells (NK), dendritic cells, and cytokines.

AHCC® is a biological response modifier (BRM) which means it stimulates the immune system to promote health and wellness when the body is under duress.  The glucans in AHCC® can be easily absorbed, allowing quick and effective interaction with the immune system.

AHCC® can modulate, suppress, and /or strengthen the response of the immune system depending on the perceived threat.

AHCC® has been used for many years to support immunity and overall health. Modern science has researched its broad range of immune benefits, from responding to viral infections and cellular integrity to supporting the gut-immunity connection. *

AHCC® is one of the best researched nutritional supplements in the world, with remarkable efficacy and an impeccable safety profile based on over 30 human trials as well as over 100 pre-clinical trials that have been completed at leading global research institutes and Universities.**

100% Pure AHCC®

Shiitake Mushroom Extract
(Lentinula edodes)

Immune Modulation & Response| Supports Natural Killer Cell Activity | Overall Wellbeing*

Shiitake Mushroom Extract (Lentinula edodes)

The data shows that the glucans in AHCC® are adept at stimulating the immune system to promote health and wellness.*
This patented extract is produced by Amino Up Chemical Co. LTD in Japan. Amino Up uses an extensive manufacturing process that involves cultivation, decomposition by enzymes, sterilization, concentration, and freeze-drying, ensuring the safety and efficacy of every batch.

Verified as authentic by Alkemist Labs

AHCC® boosts immune response by supporting various immune cell functions. *

Partner your AHCC® with Papillex®

Your questions,
answered.

What is AHCC®?

AHCC® (Active Hexose Correlated Compound) is a nutritional supplement derived from shiitake mushroom, traditionally used to strengthen the immune system by stimulating the production of white blood cells and enhancing the body’s response to viral infections. Backed by over 30 human clinical trials, AHCC® improves immune function and is manufactured through a controlled patented process by AminoUp Chemical Co. Ltd.

AHCC® by Wellex is designed for individuals looking to enhance their immune health, particularly during times of increased stress, illness, or recovery. It can also support the body’s response to HPV and can be taken with Papillex® for a synergistic effect.

AHCC® can generally be taken alongside other supplements or medications. However, it’s always best to consult your healthcare provider before combining products, especially if you are taking immunosuppressants or medications metabolized by the CYP450 2D6 pathway.

Generally, a serving of 1-3 grams daily is recommended for general immune support. Higher servings may be taken to support the immune system in response to more specific conditions. For HPV, clinical trials have shown benefit with 3g daily (2 capsules three times a day or 3 capsules twice a day). AHCC® can be taken with Papillex® synergistically to support the body’s response to HPV.

The timeline for AHCC® to begin showing effects can vary based on individual health factors. Some people may notice benefits within a few weeks of regular use, while for others; it can take longer depending on individual health factors and the specific health goals of supplementation. It can be helpful to track general health indicators to monitor progress over time.

AHCC® can be taken short-term as a proactive measure during periods of increased stress or potential exposure to infections, or it can be used long-term as part of a maintenance regimen for ongoing immune support. It is advisable to periodically review its use with your healthcare provider to ensure it continues to meet your health goals.

Store AHCC® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy.  Keep out of reach of children.

AHCC® is a naturally derived supplement. But not all AHCC® is derived equally. Quality sourcing is key.

Real reviews,
real results.

Customer Reviews
4.9 Based on 86 Reviews
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Filter Reviews:
A
04/12/2025
Anonymous
US US

HPV

I highly recommend this product. I cannot exaggerate on the way my body began to feel better from the inside out. I tested positive for HPV early this year and I discovered this bottle trying to find a remedy. I am now going to purchase my first bundle to continue my process! Praying to receive negative HPV results at my one year post checkup !!

A
04/10/2025
Anonymous
US US

I feel so much better with just the 30 days double dose a day supplements

A
04/10/2025
Anonymous
CA CA

Immune system strength

Since starting AHCC a couple years ago I have only been sick once. It passed by super fast as well! It helps my immune system stay at peak strength. It's not cheap, but I am a firm believer and have been purchasing this product regularly ever since

K
04/08/2025
Kiana
US US
I recommend this product

Surprised!

I was very lost and upset after receiving a positive HPV diagnosis. I didn’t know what to do or where to start. I know that I caught HPV at some point between September 2022- January 2024. I tested positive in July of 2024. I was so scared because I wasn’t sure if it was too late before damage had been done, but thankfully I came across these vitamins. I made an appointment for March 2025 with my gynecologist and began taking AHCC and Papillex once a day from November-December. I continued taking both vitamins January - March but admittedly not every day. I chose not to tell my gynecologist about my positive HPV text result since she was running new labs on me anyways. To my surprise, I received my results today clear of HPV and no sign of lesions. A completely normal PAP! The only thing I changed in my daily regimen was taking these vitamins. I am so very thankful and can say 100% worth the price.

A
04/07/2025
Anonymous
US US

Love AHCC

AHCC has been a game changer in my health and wellness. One year ago I received an abnormal pap with a trace of high risk HPV. After one year of taking this supplement my pap came back normal. My doctor stated “fabulous results”. It’s hard to explain but I feel a difference in my overall health. Highly recommend to women who are seeking a way to create a healthier and balanced uterus as well as reproductive health!

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