Simplix®
Your Ultimate Immune Defense:
- Optimize your body’s immune system response during cold and flu season*
- Nutrients that help support the body’s immune response to cold sores*
- Help reduce everyday stress on the body which can compromise immunity*
- Replenish the essential nutrients critical to immune function*
Formula
Clinically researched medical botanicals and nutrients in the only formula of its kind.
- Every ingredient is clinically researched to contribute a specific action, which when taken together, work in synergy to create a comprehensive system of response
- Clean formula with clinical servings and high bioavailability
- High in Antioxidants
- Meets or exceeds FDA & Health Canada Standards
Directions
- 60 capsules per bottle
- Take 2 capsules twice daily for active periods. Take 2 capsules once daily for maintenance support. With or without food. (Or as directed by your health practitioner)
Quality Standards
Immune Support, Made with Integrity
Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free
Made in America
Clean, Evidence-Based Ingredients
3rd Party Tested
Clinical Servings
cGMP Certified
Doctor Formulated
Filler Free
Gluten & Major Allergy Free
Experience the Simplix® Advantage
Comprehensive Immune Optimization
Simplix® contains ingredients with extensively researched immune supporting properties.* It works through multiple pathways to help optimize immunity: supporting viral regulation, stress reduction, and replenishment of essential nutrients.*
A Breakthrough Solution
What sets Simplix® apart lies within the synergy of our two natural biomes – Land & Sea. These biomes house immune-boosting agents known as sulfated polysaccharides. These unique compounds, found in edible mushrooms and wild seaweed, form the foundation of Simplix® .
Enter Cold & Flu Season with Confidence
As viruses evolve and we as a society are more engaged in optimizing our immunity, some over-the-counter products are facing scrutiny for their lack of efficacy. Simplix® represents the pinnacle of nutraceutical innovation, a beacon of science-backed immune support.
Respond with Confidence
For the millions of people who experience cold sores and thought there had to be a better way, we heard you. Simplix® offers revolutionary proactive support through a synergistic formula. *
Simplix® uniquely combines evidence-based
Land & Sea ingredients.
Kelp (Laminaria japonica) and Seaweed (Chondrus crispus)
Kelp (Laminaria japonica) and Seaweed (Chondrus crispus)
Shiitake Mushroom (Lentinula edodes)
Shiitake Mushroom (Lentinula edodes)
Andrographis
Andrographis
Glycyrrhiza (Licorice root)
Glycyrrhiza (Licorice root)
Melissa officinalis (Lemon balm)
Melissa officinalis (Lemon balm)
Vitamin B12, C and Zinc
Vitamin B12, C and Zinc
L-lysine
L-lysine
Clinically Researched Ingredients
Published: Biotechnology Reports, Volume 38, 2023
Seaweed and Antiviral Properties
Study Design: The study evaluated the antiviral potential of compounds derived from red algae.
Findings**: Compounds extracted from red seaweeds significantly reduced GFP fluorescence, indicating strong antiviral effects. GFP fluorescence in the study served as a marker for viral activity, with lower fluorescence levels reflecting reduced viral presence.
The effects were dose-dependent, meaning higher concentrations of the algae-derived compounds led to greater inhibition of viral activity.
The algae-based extracts demonstrated notable antiviral efficacy in the study.
Published: Frontiers in Microbiology, May, 2018
Shiitake and Influenza
Study Design: This study explored the potential anti-influenza activity of shiitake mushrooms in controlled laboratory settings. The research examined their effects on viral replication and immune response in cell cultures.
Findings**:Shiitake mushroom extract appeared to reduce influenza virus replication during the early stages of infection, possibly by interfering with viral entry into host cells.
Published: Frontiers in Immunology, Volume 13, 2022
Kelp and the Immune System
Study Design: This study investigated the potential immune-regulating effects of fucoidan, a natural compound extracted from the seaweed Laminaria japonica, in a controlled model of weakened immunity. Researchers aimed to understand how fucoidan influences immune function by examining its impact on critical immune components.
Findings**:Fucoidan improved the size and function of key immune organs, such as the spleen and thymus, and enhanced the activity of immune cells like lymphocytes and macrophages.
Fucoidan increased levels of important immune-supporting proteins in the blood, including IL, TNF, and IgG, which are essential for fighting infections and maintaining immune balance.
Your questions,
answered.
Who is Simplix® made for
Simplix® is designed for individuals looking to support their overall health and immune function. It combines immune-boosting mushrooms from the land and seaweeds from the sea to enhance your body’s response to cold sores, colds, flu, and other viral invaders.
Can I take this with other supplements or medications
Simplix® can generally be taken with most supplements and medications. However, it’s advisable to consult a healthcare provider, particularly if you are taking immunosuppressants or medications metabolized by the CYP450 2D6 pathway.
When and how do I take it
For ongoing maintenance, take 2 capsules daily. During times of active support, take 2 capsules twice or thrice daily. If swallowing supplements is a challenge, Simplix® capsules can be opened and mixed with a small amount of liquid.
When will it start to work
The timeline for Simplix® to begin showing effects can vary based on individual health factors. Some people may notice benefits within a few days to a few weeks, while for others, it could take longer. Consistent use is recommended for the best results.
Can I take it if breastfeeding
As with all dietary supplements, it’s best to consult with a healthcare practitioner for more specific information regarding your case and needs during post-partum.
How long do I take it for
Simplix® can be taken short-term as a proactive measure during periods of increased stress or decreased immunity, or it can be used long-term as part of a maintenance regimen for ongoing immune support. It is advisable to periodically review its use with your healthcare provider to ensure it continues to meet your health goals.
How do I store Simplix®?
Store Simplix® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy. Keep out of reach of children.
Over a decade in the making, Simplix® is designed to nutritionally support a healthy immune system and overall wellness.
Real reviews,
real results.
- Reviews
- Questions
USGreat customer service
Packaging and experience with customer service was top of the line.
USFinally HPV Free after 6 years
I received an abnormal pap with HPV detected back in 2019. I have been doing nearly year paps since then, with every single one coming back HPV positive. I've had one colposcopy where they took a biopsy, and that experience was some of the worst pain I have ever had in my entire life. I was beginning to feel hopeless, as everyone else appears to clear their HPV within 2 years--why was mine lasting so long?? A friend recommended AHCC, and in my search for it, I came across Papillex. I first ordered the original Papillex bottle and began taking only two tablets of that, not super regularly, about two months before my last pap in the summer of 2024. It came back HPV positive again, and my doctor agreed that I would try a strict regimen of Papillex and AHCC combined until January, when I'd have another pap. Hoping this would be a Hail Mary, I took daily two pills of Papillex and two pills of AHCC, with only missing a few days here and there due to travel. I had another pap end the end of January 2025 and it came back negative. I literally cried. On top of clearing my 6 year fight with HPV, these pills have seemed to boost my immunity in general. I have not gotten sick, even after spending time traveling, at people filled concert halls, and working in health care where everyone around me is dropping like flies to Norovirus. I will continue to take these pills, for their immunity boosting properties. I am also fearful of HPV returning if I stop taking them. If you're doubting purchasing these because of the cost, I am telling you, IT IS WORTH EVERY PENNY!!
USReally Works 100% No Joke!
I am wholeheartedly grateful to the Most High God that this really works wonders! It is truly amazing how our bodies heal themselves if we create the right environment for them. Taking this supplement empowers us with the essential nutrients and God made goodness for our bodies to be able to heal and repair themselves. I am a new creation after taking this… visibly, tangibly, objectively. 100% bonafied legit success and victory over HPV and great overall wellness empowerment! Amen.
