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Antioxidants for Immune Support

Antioxidants for Immune Support

Victoria Gasparini
‘Antioxidant’ is a term that has been known in the general social consciousness for quite sometime now. Most of us know that when something is an antioxidant, that’s a good thing and that you want more of it. Not as many people know what exactly an antioxidant IS and what makes it so good for us. An antioxidant is actually an attribute of many different molecular compounds that allows them to prevent oxidative damage to our cells from free radicals. Harmful substances (for example, pollution, cigarettes, UV rays, and toxins) cause damage by stripping electrons from the surfaces of molecules. Damaged molecules cannot carry our their functions, which impairs the cells they are a part of. The immune system then has to come in and clean up the mess, and the body has to repair the damage and regenerate those tissues (if it can). An antioxidant compound can help prevent electron stripping (oxidation) by donating “spare” electrons to the harmful substances, so they no longer need to strip them elsewhere. This is is why having sufficient antioxidants in the body is so important, because without them, the oxidative damage would add up too fast, and the stress on the immune system and the body in general would be to great.  When in comes to the immune system specifically, antioxidants are a critical support system. Free radicals can actually be generated by immune cells as a weapon against invading pathogens such as viruses, and antioxidants are required to “mop them up” when the assault is done. Moreover, immune cells themselves are susceptible to oxidative damage, so those antioxidants will help protect them too. The balance here is very delicate and many illnesses can boil down to an imbalance in the oxidant-antioxidant systems, both from internal malfunction and from damaging substances from our environment.  Antioxidants can be found abundantly in healthy, plant-forward diets, as well as supplemented. So many natural substances posses antioxidant abilities. Here are some well-established examples: green tea extracts, turmeric, quercetin, Coenzyme Q10, Alpha-lipoic acid, vitamins C, E, and A, minerals such as selenium and zinc, polysaccharides from mushrooms and seaweeds, and many more. For your diets, look for fruits and vegetables that have bright, deep, saturated colours – that’s an easy way to tell right away that it will be high in antioxidants. Interested in learning more about antioxidants and their impact on HSV? Follow us on instagram.
Feb 13, 2023
2 min read
5 Steps to a Healthier "Down There"

5 Steps to a Healthier "Down There"

Victoria Gasparini
Many of us have come to accept that womens health issues such as dryness, infections, cervical dysplasia and pain in the vaginal canal are all normal parts of being a female. But what if I told you this does not have to be your reality? There is a great deal you can do to control and prevent vaginal infections, make intercourse and sexual experiences less or not painful at all, and even heal and prevent cervical dysplasia. Some issues commonly experienced by women are, vulvovaginitis, vaginismus, bacterial vaginosis, and yeast infections. Women may also experience cervical dysplasia caused by HPV, and gential lesions from HSV.  Because the above issues are so common in society, they are rarely taken seriously in the medical community, but for most of us women, they do impact our quality of life and our ability to be our true authentic selves.  Here are 5 steps to a healthier “down there”  Lifestyle Oral contraceptive use Many women rely on oral contraceptives for a variety of hormonal-related issues, as well as for contraception. While the pill is an important part of many of our personal lives, there are some negative implications to our vaginal and cervical health that come with taking them. For example, oral contraceptives that contain estrogens can increase incidence of yeast infections. Additionally, oral contraceptives increase your risk for worsening HPV-related symptoms. Though the research is still blurry when it comes to how birth control can increase cervical cancer risk, we do know that taking oral contraceptives depletes many key nutrients that are required to help us keep our HPV inactive. The pill can deplete riboflavin, vitamin B6, folic acid, vitamin C, and zinc. We know these nutrients are important players in supporting the immune system and some have even been specifically linked to HPV. Moreover, the birth control pill is also known to alter the gut microbiome. The pill may increase leaky gut, dysbiosis, and candida overgrowth. A healthy gut is another foundation for our immune and overall health. Impairing this system can have a widespread impact on the rest of the body. Finally, certain types of birth control pills can affect your sex drive, impacting your intimacy, sexual health and ability to feel lubricated.  Vaginal ecology disruptors Antibiotics, sanitary products like tampons and pads, and steroid-use can all impact our vaginal health and microflora. The good news is we can reduce or avoid these environmental triggers. Antibiotics, while incredibly necessary and helpful when needed, can do immense damage to the vaginal microbiome. By keeping our immune system healthy (by using the tips from our blogs), you can hopefully prevent chronic infections that require antibiotics.  Sanitary pads and tampons typically contain harmful ingredients such as bleach, and can be avoided by purchasing organic 100% cotton ones, or switching to a menstrual cup or menstrual underwear. Never, ever douche. It’s 2023, let’s stop trying to convince women that their vagina’s should smell like flowers. Our vaginas are self-cleaning machines. All you need is water or a gentle soap on the vulva area (the area surrounding the vagina), and that is it. In fact douching your vagina changes the pH and can actually result in more infections and even a foul smell down the line. Safe sex is enjoyable sex We are all for practicing safe sex as a way to reduce viral transmission, the incidence of BV and UTI’s but also to prevent unwanted pregnancies. However, typical latex condoms and chemical laden lubes might be the sneaky reason behind your vaginal infections that seem to pop up every time you get intimate.  Skip the traditional brands and go natural where possible. Many lubes and condom companies are now offering “spermacide-free” condoms, and chemical-free lubes. Typical lubes can disrupt the vaginal flora and pH leaving us at a higher risk of developing vaginal infections.  Food Food truly is medicine, and can help us prevent and handle all kinds of women's health issues. Phytonutrients can help us with healthy vaginal tissue, lacto-fermented foods can help nourish our microflora, and balancing our blood sugar can help support vaginal ecology while also preventing recurrent HPV related flare-ups. Though I know it can be tempting to reach for the bottle of wine after a long day of work, we recommend skipping that glass when possible and opting for a sparkling water, or alcohol-free, low sugar option. Herbs & Nutrients Supplementation can be incredibly individual, however, Papillex was made with the intention of correcting the most common nutrient deficiencies found in women with HPV. These nutrients like folate, green tea extract and vitamin C have all been found to be extremely beneficial in women's and general health, too. We also really like to add an omega 3 to our routine for reducing inflammation, and inhibiting the growth of HPV cervical cells. Finally, AHCC has been shown to clear even high-risk strains of HPV after several months of use. Talk to your health provider about what supplementation is right for you. Mind-body connection When it comes to starting your holistic healing journey, we believe the best approach includes a strong mind-body connection. More and more studies are finding a link between past traumas, adverse childhood events, and high levels of stress with vaginal infections and conditions like vaginismus. Dealing with these issues is likely the hardest but most important part of true healing. If you had the chance to tune in to our instagram LIVE last week with women's integrative health coach, Denell (@cervicalwellness) and founder of Papillex, @drgoldspink, they had an incredible and inspiring conversation about the psycho-emotional aspect of healing conditions like HPV and cervical dysplasia. If you did not get a chance to see it, head to our instagram this week to check it out. Therapy We are big advocates for talking it out. Therapy, a good partner, good friendships, online or in-person support groups, a good primary care provider, naturopathic doctor, pelvic floor therapist or healer of any kind can really help you with these intense but important breakthroughs that can hopefully kickstart your healing from all sorts of problems we see happening “down there”. Sadly, there is a stigma around many of these conditions, so much so that I had to avoid using the term "vagina" in the title of this blog post. It's time we start talking about these issues that so many of us face. Interested in more tips of healing vaginal infections, cervical dysplasia, HPV and/or HSV? Follow us on instagram to continue the conversation.
Feb 06, 2023
5 min read
Stress and Vaginal Infections: What's the Link?

Stress and Vaginal Infections: What's the Link?

Victoria Gasparini
Stress is a normal part of our lives, and our bodies are made to handle these stressors through a tightly regulated hormonal system. Hormones that are involved in stress include adrenaline, epinephrine, norepinephrine and cortisol, to name a few. We rely on these hormones to protect us against the impact of physical and emotional stressors, and without this system we, nor our ancestors, would have ever made it this far.  The impact of stress is widely recognized in medicine, but it isn’t actually stress itself that is the problem. In today’s day and age, it’s the everyday, low level stressors that are having the most impact on our health. Chronic stress is the silent killer.  In the olden days, true stress was usually a result of two things: widespread famine and/or being chased down by a wild animal. In these crucial moments, our ancestors' hormonal system adapted to stressors like these by producing mass amounts of stress hormones, adrenaline, epinephrine and cortisol. This temporary surge of hormones allowed us to store excess fat around the belly (in times of famine), shut down reproductive function (because who wants to get pregnant when there’s not enough food available?), and to run extra fast to escape that wild animal. The production of stress hormones is a survival mechanism that is adaptive to the stressors of the time. Cortisol, otherwise known as the “fight or flight” hormone, is the main driver. But we don’t have the same problems as our ancestors anymore. Now, our society works 9-5, sits in traffic for several hours, and deals with much more minor stressors than our ancestors did. It's this low level, chronic stress that is wreaking havoc on our society, our microbiome, and the chronic disease epidemic as a whole. The vaginal microbiome: how chronic stress impacts the vagina and your overall health The vagina is an incredible organ with a protective epithelium and diverse microbial ecosystem. The vaginal tract is rich in all sorts of “commensals'', meaning microbes that are non-harmful and even beneficial for the vagina and our health. The largest species of microbes in the vaginal tract are called lactobacillus, which you may have heard of if you take oral probiotics. Any potentially harmful microbes in the vagina are kept at bay by our unique acidic pH. So, how does chronic stress throw this strictly regulated system out of balance? Science suggests that cortisol inhibits vaginal glycogen deposition which then leads to infection. Our estrogen production as females increases the vaginal glycogen & epithelial maturation that is necessary to maintain adequate vaginal health. Chronic production of cortisol disrupts this important process. What can you do?  Since stress itself is inevitable, cortisol has the capacity to disrupt the vaginal microbiome and its ability to fight infections of the genitourinary tract. Researchers from the University of Illinois have even found a potential link between pandemic-related stress and the increase in STI’s amongst young women. The data from this small, but fascinating study found that young women who reported higher levels of pandemic-related stressors also had increased odds of infection. Professor of epidemiology and biostatistics, Mehta, suggests that the uptick in stress-related infections is likely due to changes that occur in the vaginal microbiome during times of chronic stress. This study sheds light on the impact of environment & psychosocial factors on our physical health, as women. Another study in the Frontiers of Endocrinology found that exposure to chronic stress led to a significant decrease in lactobacillus microbes in the vaginal tract. As mentioned above, the lactobacillus species is one of the most significant “commensals” in the vagina, providing us with protection against invaders and therefore amplifying both the severity and frequency of vaginal infection. In addition to infection, women can actually experience decreased libido and increased vaginal dryness as a result of cortisol suppressing sex hormones like testosterone. Do you see how important it is for us to get a handle on our stressors? But how? Handling stress in stressful times Address nutrient deficiencies Did you know, it's not just mental and emotional stress that increases susceptibility to infection? Nutrient deficiencies are a significant physical stressor on our body and lead to a suppression of immunity and therefore an increase in infections, like HPV and bacterial vaginosis. Taking your daily dose of Papillex is a wonderful, evidence-based way to correct some of the most important and prevalent nutrient deficiencies in our community. Try therapy Sometimes stressors are rooted in childhood or other areas of our lives that we may need help exploring with a professional. Therapy can help you uncover some of the root causes of your vaginal infections, and address the stress that is potentially causing them. Because women's health research still lacks in many areas, we do not currently know the exact link between trauma and vaginal-related infections, but more and more research is pointing us in that direction. There is no shame in therapy. It might just be the step you need to take to move your healing journey in the right direction. Protect the immune system Once you have addressed nutrient deficiencies and the root of your stress, adaptogenic herbs and mushrooms are an incredible addition to your healing. We love to use herbs like Ashwagandha, which has been shown in studies to not only reduce the impact of stress on the body but also reduce our actual perception of the stressor that is occurring. Additionally, mushrooms like AHCC have been used in traditional medicine for centuries to help combat a wide variety of infections, and have recently been studied for clearing high-risk HPV. A combination of herbs and mushrooms, unique to your physiology, can be a crucial addition to your treatment plan. Check out our instagram for more tips on healing HPV.
Jan 02, 2023
4 min read
Managing HPV with Green Tea Extract

Managing HPV with Green Tea Extract

Victoria Gasparini
Whether living with low or higher risk strains of HPV, the condition often comes with a list of unpleasant symptoms. Genital warts are the most common complaint of those with low to moderate risk HPV, while the risk of cervical cancers with higher risk strains are the most worrisome of all.  The good news is, there are ways to naturally manage your HPV and hopefully help prevent the recurrance of unpleasant symptoms like genital warts as well the diagnosis of cervical cancer.  Green tea extract is one of the many well-evidenced nutrients in Papillex™. Green tea extract is high in compounds called polyphenols which have many medicinal uses in human health, as well as in HPV. Green tea extract has been used in traditional medicine for centuries with studies now finding benefits of tea compounds in the management and prevention of heart disease, autoimmune disorders, neurodegenerative diseases and even various cancers. Additionally, compounds in green tea have been studied and found to clear and prevent the recurrence of genital warts caused by HPV.  Green Tea and HPV Green tea extracts like theanine, polyphenol E and ECGC have all been found to have powerful medicinal properties. Theanine has been studied as a stress-reducer and concentration enhancer (especially when paired with a cup of coffee), while polyphenol E and ECGC have been linked to the clearance of HPV-related genital warts and possibly even the prevention of cervical cancers.  Both compounds help protect cells from oxidative stress and are anti-inflammatory in nature. ECGC and Polyphenol E play a role in the production of T cells and T reg cells, helping to modulate our immune response and fight off viral infections like HPV. These compounds have also been found to aid in stopping the spread of HPV-related cancer cells in the body, inhibiting cervical epithelial and cancer cell growth.  A south Korean study of 51 patients with cervical dysplasia taking 300mg of GTE per day for 8-12 weeks found a reduction of 69% of cervical dysplasia lesions, compared with placebo. Another study in the British Journal of Dermatology found that topical GTE used on genital warts caused by HPV was 2-folds more effective in clearing lesions than in patients who did not use the extract. Additionally, the group using topical GTE avoided recurrence of lesions 12 weeks after treatment.  Does drinking green tea provide the same benefits?  Drinking green tea, while a very healthy addition to your day, is not often enough to treat or prevent HPV-related lesions. In fact it would likely take 20-30 cups per day to achieve desired results (which we obviously would not advise consuming). However, some studies suggest daily moderate to high consumption of daily green tea may play a role in preventing cervical cancer development in someone with HPV, though more research is still needed.  There are two ways in which you can add GTE to your HPV-healing routine. The FDA has approved a topical ointment called ‘veregen’ for the treatment of genital warts caused by HPV. Studies have found that using the topical treatment, combined with an oral green tea extract may be the most beneficial.  Papillex contains the therapeutic dose studied to clear HPV-related lesions and reduce risk of cervical cancer, with the addition of other powerhouse herbs and nutrients also research backed and informed in the management and clearance of HPV. Combing topical and oral green tea extract might just be the dynamic duo you've been missing.
Dec 06, 2022
3 min read
Zinc for Immune Support

Zinc for Immune Support

Jenny Henderson
What Zinc Does for Us Zinc is an important element for many functions of the body. It has a role in many cellular processes all over the body, where it assists enzymes, protein synthesis, and tissue formation. Being deficient in zinc can results in quite a few issues, such as impaired healing, lowered immunity, and degenerative changes such as hair loss, weakened tissues, and impaired growth in children. When it come to the immune system specifically, an adequate amount of zinc will ensure that the immune cells that respond broadly to infectious pathogens are able to replicate and mature correctly. It also supports that proper barrier functions of the skin and mucosa.  How To Ensure Adequacy It is quite clear then that zinc adequacy is critical for health. Generally, a well balanced and healthy diet will supply enough zinc. However deficiencies are very common worldwide, and certain conditions can make deficiency more likely, such as inflammatory gastrointestinal conditions that could impair absorption, restrictive vegan diets, or in young children and the elderly whose diets may be lacking. Some foods that are high in zinc include nuts, seeds, meat, seafood, and legumes. Zinc supplementation is also an option. This has been studied quite a bit for a variety of conditions, and while results tend to be mixed in terms of efficacy, there is evidence that zinc supplementation could be useful for eye health, supporting the immune system, viral infections, inflammatory conditions, and cardiovascular parameters. Given how many ways zinc is involved in cellular health, it is not surprising to see that it might be effecting at treating a wide variety of issues. What about HSV? Some studies have shown specific benefit against Herpes Simplex virus, the globally ubiquitous virus that causes cold sores and genital herpes. It appears that it may do so through interfering with the way the virus replicates, and therefore may reduce the burden of infection on the host cells. Moreover, it can work both when taken internally, or as part of a topical cream. References https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0714.2005.00327.x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820120/ https://pubmed.ncbi.nlm.nih.gov/9701160/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628855/
Nov 22, 2022
2 min read
Change of Season Soup: An Immune Boosting Hack

Change of Season Soup: An Immune Boosting Hack

Victoria Gasparini
I’ll admit, I'm a bit autumn-obsessed. I love a cozy sweater, some jazz music, the leaves falling and a warm cup of anything pumpkin spice. I also love the idea of new seasons, and new opportunities. Anytime the seasons change I take it as an opportunity for growth and change - and love the feeling of starting fresh! Unfortunately, my immune system doesn’t share the same kinda love for the season, and as winter creeps around the corner, I know I need to arm my immune system with some of the best tools nature has to offer. In Traditional Chinese Medicine, the changing of seasons and the body’s adjustment to new temperatures often leaves our immune defences depleted and vulnerable. I am sure you’ve already begun to notice an increase in respiratory issues either personally or around you in the last little while - and if you live somewhere with a snowy, cold winter like I do, it usually only gets worse from here. If this sounds like your situation, don’t fret. We have just the thing for you to try this season to support your immune system and get you ready for the changing season. It’s called, “change of season soup”, and it’s one of my favourite hacks for a strong, healthy immune system. Here’s what you’ll need: Herbs Astragulus: 4 sticks Dry ginger: 1tbsp Codonopsis: 3 sticks Chinese wolfberries: 3tbsp Chinese Wild yam: 2 sticks Chicken & Marinade 400g of skinless chicken, cut into pieces (feel free to include the bone for added nutrients) 2tbsp of fresh grated garlic 2tbsp of fresh grated ginger salt and pepper to taste Optional add-ins 1 cinnamon stick 5 cloves 5-10 peppercorns Final Additions 1/2 cup thinly sliced carrots 1/2 cup celery, chopped 1 cup chopped bok choy 1/2 cup onion, chopped 1 cup shiitake mushrooms (dried or fresh) fresh coriander to garnish optional: 2tbsp of turmeric powder Instructions to Cook Start with marinating the chicken and leave in the fridge overnight Put your herbs into a big soup pot filled with water (about 15cups) or if you make your own broth, that’s even better! Add the marinated chicken and your optional add-ins (feel free to add anything you would like) Boil the water, cover & simmer for 1.5 hours or until chicken is fully cooked. (If making the soup without chicken, simmer for only 1 hour). Remove the astragalus, codonopsis and chinese wild yam from the pot Add the final addition ingredients of carrots, celery, bok choi and onions as well as any vegetables of your liking and continue to simmer for 20 more minutes Let it cool and add garnish If you are interested in why we use these specific herbs in this recipe, here’s some science on their uses: Astragalus – astragulus root is known to protect the immune system, improve our energy and tonify the lungs. This herb has the capacity to increase natural killer cell production, which helps our body fight off viral infections Codonopsis – codonopsis root is believed to increase immune defences by tonifying and strengthening our “Qi”, which is our body’s vitality and overall energy. Chinese yam – this root is used for the lung, and is also rich in polysaccarides, which has been linked to a healthy immune system. Chinese wolfberries – tcm physicians actually prescribe these tp protect the kidney and liver. They are abundant in antioxidants and protect the body from free radical damage. I made this soup a few weeks ago and had it each day for a week to help boost my immune system during this change of season. I am also allowing myself to take lots of rest as my body requires, and remembering to take my AHCC each day to help my immune system combat incoming infections. I am prioritizing light movement, instead of over-working my body, and drinking more water throughout the day. I am also incorporating more warming foods so that my body does not have to use excess energy to keep me warm. Happy change of season, everyone!
Oct 31, 2022
3 min read
How Can Naturopathic Medicine Play a Role in Your HPV Treatment Plan?

How Can Naturopathic Medicine Play a Role in Your HPV Treatment Plan?

Victoria Gasparini
Did you know that Papillex was founded and uniquely created by naturopathic doctors? Naturopathic medicine offers us an emerging and exciting approach to treating a myriad of conditions, including HPV and HSV. Naturopathic and conventionally trained doctors do share many similarities, but our differences allow us to provide you with a hopeful, complementary approach to healing that you likely have yet to try.  What is a naturopathic doctor?  In regulated jurisdictions, naturopathic doctors are trained primary care physicians with a similar scientific background to other healthcare practitioners, but with a different toolbox of modalities to help patients prevent, treat and heal many common conditions we see today, ranging from digestive, autoimmune and hormonal conditions to mental illness, chronic diseases and infections. Our tool box is significant - and not all naturopathic doctors will use the same tools. Some of these tools include: botanical medicine and herbs, nutraceuticals, certain prescription medications (based on licensure), acupuncture and other traditional Chinese medicine therapies, homeopathy, minor surgeries, and more.  What is the difference between a naturopath and naturopathic doctor?  This is a very important distinction when deciding whether naturopathic medicine is the right route for you and your treatment. A naturopath and naturopathic doctor are different, depending on where one practices, what their education is, and their licensure.  A naturopathic doctor is to attend a 3-4 year undergraduate degree with required pre-med courses such as physiology, biology, chemistry (organic and biochemistry), psychology and more. They are then to apply through a lengthy application process including an interview and personal essay. If selected (based on GPA, personal essay and interview), the student will then do a 4 year program at an accredited naturopathic medical school, where they are to learn in a similar format and curriculum as medical doctors. In their final year, a naturopathic medical student will work full-time under the supervision of a licensed naturopathic doctor in a clinical setting. The student will graduate and then go on to write several licensing/board exams depending on their jurisdiction and where they intend to practice.  A naturopath, on the other hand, will not be required to have any of this education. In fact, in states/provinces without regulations - pretty much anyone can call themselves a “naturopath”. This is why it is so crucial to know whether you are seeing a regulated and licensed ND (naturopathic doctor) or a naturopath. Click here to find out whether naturopathic medicine is licensed where you live.  How can an ND help you with your HPV treatment plan?  The naturopathic approach to HPV is comprehensive and includes a number of different approaches to preventing, treating and managing HPV. From a conventional perspective, naturopathic doctors will encourage regular screening, safe sex practices to prevent spread of infection, and other common practices to prevent HPV. Not only can ND’s help you through the physical complexities of the condition, but they are also a wonderful, attentive support system for the mental and emotional challenges that come with the diagnosis.  Often HPV (depending on the strain) will clear by the basic immune defences of the body but in some cases, cervical dysplasia can worsen if left unattended. We know that without adequate care and treatment, cervical dysplasias can progress and result in an increased risk of cervical cancer. Naturopathic doctors can provide you with preventative education, supplemental support, immune-enhancing practices and counselling while you navigate this infection and its whole-body impact. The greatest part is, naturopathic doctors can be a wonderful part of your medical team, working with your general practitioner to help strategize and find the best approach for your unique case. We believe integrative care is the most powerful and effective way to help a patient on their health journey.  3 ways Naturopathic doctors might approach your HPV Prevention An ND will utilize many methods to prevent HPV in their patients including educating on safe sex practices for their patient and how best to avoid potential transmission during intimacy with an infected partner. They will also likely encourage their patients to reduce their risks of worsening HPV such as smoking and alcohol cessation, and will certainly advise their patients on best steps regarding diet and lifestyle, as well as evidence-based supplementation for HPV. Diagnosis  Depending on jurisdictions and regulations in your particular province/state, ND’s are able to provide pap smears, and may refer you for a colposcopy, which uses a device to determine the degree of cervical dysplasia, and is then categorized (CIN 1, 2, or 3). A medical doctor or naturopathic doctor will diagnose for HPV and provide you with options unique to their scope. An integrative approach to managing HPV may be the missing puzzle piece to optimal health that you have been looking for. Treatment  Though all ND’s may have a unique approach, some popular and effective treatments that we encourage you to discuss with your naturopathic physician are:  Folate Vitamin C Selenium  Curcumin Omega 3 Green tea extract B12 Various antioxidants  Additionally, an ND will likely discuss dietary measures that are anti-inflammatory and focus on blood sugar control, which has been shown to help manage HPV. Naturopathic doctors have a substantial tool kit when it comes to HPV. Each case is individual to the specific patient, but we recommend looking into the above factors when finding an ND that is right for you. Looking for more information on how to take control of your HPV? Follow us on Instagram!
Oct 03, 2022
4 min read
Sulfated Polysaccharides for Cold Sores & Herpes

Sulfated Polysaccharides for Cold Sores & Herpes

Jenny Henderson
Researchers all over the world have been increasingly studying the many potentially important therapeutic benefits of polysaccharides. These complex molecules have the ability to interact with different factors in our bodies to exert various effects. Most abundantly found in seaweeds and mushroom, these varied molecules have a lot of actions. Studies have shown their ability to be anti-inflammatory, anticancer, antiviral, antioxidant, cholesterol-reducing, and much more. Moreover, these compounds are also considered safe and nontoxic, so they’re worth paying attention to. Herpes Simplex Virus (HSV) is very common and highly transmissible virus. It’s two sub-types, HSV-1 and HSV-2  cause cold sores on the face and genital herpes, respectively (though some mixing can occur). While HSV infections don’t cause very serious problems in a vast majority of people, they can have dangerous complications in some. Additionally, the virus has the ability to go into a ‘latent’ state, which is like hidden hibernation, in the body making it very difficult to clear. Most people never clear it, and it hangs around forever, showing up once in a while as a cold sore or a genital outbreak (or often without any symptoms at all). So given the general grief this virus can cause to millions all over the world, treating it is of high interest in the research community, especially given some concerns about drug resistance. This is why there is a lot of studies are looking at anti-HSV compounds that may be found in nature, such as polysaccharides. We’ve already mentioned that they are antiviral, but there is a specific subset of polysaccharides that is even more so. These are the sulfated polysaccharides. These molecules have sulfate groups attached along the chain, and the more sulfated the chains are, the more antiviral activity they seem to posses. How do they work against Cold Sore and Herpes? Sulfated polysaccharides have been shown in laboratory studies to prevent HSV from adhering and entering healthy cells (a process called adsorption), prevent it’s ability to replicate, and in some cases, even disable the virus itself (virucidal). They can do so because they have variable polarities along their length, which makes them able to physically attach to the virus and interfere with its functions. Another feature that sulfated polysaccharides have that can be handy for HSV infections, is immune-modulation. In order to keep HSV outbreaks brief and infrequent, your immune system has to be always on-point and vigilant. By interacting with various white blood cells, sulfated polysaccharides can boost how well they do their jobs. They can also reduce any excess inflammation that the immune system makes which can interfere with pathogen clearing and give the virus a more hospitable environment to thrive. The more ways in which a compound can help the body fight HSV, the less likely it will become resistant, and the more comprehensive the support will be.  The Power of Polysaccharides in SIMPLIX - Respond with Confidence References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680640/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528127/
Sep 19, 2022
2 min read

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