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The Life-Cycle of HPV

The Life-Cycle of HPV

Adrienne Hill-Strathy
Viruses aren’t living organisms but strands of DNA or RNA that make a home in other living organisms. By doing so, the viruses can survive. The life-cycle of a virus includes gaining entry into a living organism, replicating, and making itself a home. Understanding the life-cycle and how the immune system interacts with HPV can better understand why some strains develop into complications like cancer. What Makes The HPV Life-Cycle Unique? HPV includes a family of more than 150 types that have slight variations. HPV has adapted over time to target different tissue regions and cause different diseases. Most HPV infections occur around the mouth or genitals. Some infections cause visible growths like warts and others are asymptomatic. In addition to the type of HPV strain, symptoms also depend on the individuals' immune system. The immune system influences how quickly the virus is identified and eliminated from the body. Most HPV infections will complete their life-cycle without causing disease or symptoms at all. Infection Stage Infection occurs when the HPV gains entry into skin tissue, called epithelial cells. Epithelial cells line the surface of the body and can be classified into three shapes: squamous, columnar, and cuboidal. When it comes to testing for HPV and cell abnormality, squamous cells are the ones that typically develop abnormalities. Squamous cells are found in body tissue which forms the very surface of the skin. During a Pap smear, a swab is taken from this layer to examine for abnormalities. The cells meet the rest of the body through a layer called the basement membrane. This basement layer is where the HPV virus attaches and enters the cell. Once the virus has accessed the cell it can then use the cell to replicate. Squamous Cells Diagram Replication: Depending on the strain of HPV and the body the virus makes a home in, the life-cycle will have different outcomes. The virus may remain relatively silent. In this case, the virus doesn’t move beyond the basement membrane to cause disease. The virus may also begin to replicate, releasing its viral particles deeper into the host. When the virus replicates deeper into the skin tissue it is called a productive infection. Productive Infections Infections can be classified into grades CIN 1 (deregulated) to 3 (high-grade neoplasia). Persistent high-grade infections at CIN2 or CIN3 can further lead the virus to integrate into the individuals' genes. This puts the individual at greater risk of developing cancer. Some areas within the cervix lining are more susceptible to infection. HPV that gain access to the transformational zone in the cervix have been linked to higher rates of cancer progression. Two viral proteins, E6 and E7, have also been found on high-risk strains of HPV. These proteins are thought to be responsible for stimulating cell cycle entry into the upper epithelial layers and linked to cancerous changes. Latency In most cases, HPV will not reach a cancerous state. The majority (80-90%) of HPV infections will clear on their own. Even high-risk strains will likely be cleared by a local immune response. The virus gets inactivated through interaction with our immune system. In a healthy immune system, active infections will stimulate immune cells called CD4+ T cells. The presence of CD4+ T cells activates more immune molecules to overtake the virus. A compromised or weak immune system appears to increase HPV infections. In viral latency, viral particles continue to exist within the basement membrane in an inactive state. However, the virus can get reactivated following a change in immune status. What Makes Certain HPV Subtypes More Carcinogenic? In order for cancer to develop, the virus has to go undetected by the immune system over a prolonged period. Certain subtypes of HPV, like HPV-16 and 18 are more powerful carcinogens. What makes the virus carcinogenic is its ability to invade the cell layer for longer periods of time allowing changes in the gene expression of the underlying tissue. It is thought that the presence of E6 and E7 proteins on high-risk strains allows for cervical abnormalities to occur. How Can You Assist Your Immune System? It is clear from the research that a healthy immune system is key to preventing HPV infections from reaching a cancerous state. Diet and lifestyle create the foundation for a healthy immune system. Some important factors in supporting your overall health include: Optimizing nutrition and supplementation: Consuming fruit and vegetable-rich diet, limiting sugar and refined carbohydrate intake has a positive effect on the immune system. Managing psychological stress: Prolonged stress can imbalance the ability of the body to fight incoming infections. Engaging in daily stress management practices like meditation, exercise, and socializing can have a positive effect in improving the body's overall resiliency. Getting good quality sleep: Getting adequate rest, or seven to eight hours of quality sleep per night allows the immune system time to revitalize. Adequate sleep balances hormones and initiates cellular repair. Setting a regular bedtime, limiting caffeine intake in the afternoon, and eating a nutrient-dense diet are all ways to improve your sleep quality. Engaging in regular exercise and movement: From improved circulation to naturally increasing the immune cells, staying active has a range of benefits in helping support health and prevent disease. We recommend taking daily walks and engaging in bi-weekly strength training and aerobic activity.
Mar 01, 2021
4 min read
The Side Effects Of HPV

The Side Effects Of HPV

Adrienne Hill-Strathy
HPV is very widespread amongst the population. It is estimated that 80 percent of women will contract a strain of HPV in their lifetime. Most of these infections are silent, causing no visible symptoms or side effects within a host. In about 90 percent of patients, a healthy immune system will typically develop an immune response to regress the virus within a period of 1 to 2 years, with most in fact regressing over the course of a few months. However, a small number of people who contract an HPV infection may have symptoms or complications that range from low-risk visible papilloma’s on the skin to persistent chronic infections that may develop into precancerous or cancerous lesions. Here, we outline a few of the most common symptoms of HPV, including potential side effects of HPV vaccination. HPV Symptoms Typically, if HPV symptoms do develop, they will either cause visible warts on the surface of the skin or cause chronic infections that persist within the cell tissue and are only detected through clinical examination, like a pap smear. Warts The large variety of HPV strains gives rise to several different types of warts on the body surface, face, and genital areas. These warts can be classified into: Common warts: the common wart is most frequently caused by HPV-2. These warts usually present with an irregular shaped rough nodule that shows up in multiples. Plane warts: mostly caused by HPV-3, 10, or 28. They cause small and less rough, flesh-colored, or lightly pigmented lesions. Usually on the hands or face. Plane warts have an unusual characteristic in that they can spontaneously regress and cause swelling and a rash at the surface of the skin. Plantar warts: usually found in 10-14-year-olds. They are contracted through barefoot activity and are found on the bottom of the feet. Plantar warts are typically caused by HPV 1 and 2. Genital warts: are most frequently caused by HPV 6 and 11. They are renowned for their resilience and ability to continually come back, as well as being both painful and irritating. Cancerous or Precancerous Changes in the Cells of the Cervix Only a few of the over 180 different strains of HPV are associated with increased cancer risk. HPV that causes cervical, anal, or oral cancer is typically caused by a few high-risk strains of HPV that infiltrate the epithelial cells and have developed special mechanisms to evade the immune system. There are typically no symptoms that HPV is developing into cancer until several years of cell proliferation and development. HPV that has progressed to a stage of cervical cancer may present as symptoms of abnormal vaginal bleeding. The fact that it takes many years for HPV to develop into cancer is both a positive and a negative for us because it gives us time to detect the virus at an early stage in development before it has progressed into cancer and take action. It is negative because having no symptoms can prevent some people from being proactive about their health, allowing the situation to progress to a more serious state. Typically, Pap screening should be done every three years from the age of 21 to 65 to screen for these abnormalities. The HPV Vaccine and Potential Side Effects Today, we have a vaccine offered as a preventative measure against high and low risk HPV strains, primarily to protect women against cervical cancer. The Centers for Disease Control and Prevention recommends the HPV vaccine for routine vaccination at age 11 or 12 years. The vaccine may be started as early as age nine. Females aged 13 to 26 and males aged 13 to 21 are recommended to receive the vaccine. The vaccine is only recommended past the age of 26 for gay, bisexual, transgender, and those who have chronically weakened immune systems. Gardasil is the most commonly used vaccination, protecting against the two strains of HPV that cause genital warts, and the two strains that are the most high-risk HPV strains, commonly known to cause cancer, such as cervical cancer. Two doses of the vaccine should be given, the second being 6 to 12 months after the first. If less than 6 months apart, the recipient is of a weakened immune system or is past the age of 15, three doses are required to ensure the vaccination is effective. It is important to keep in mind that the vaccination does not protect you against all HPV strains, just the most high-risk, so routine screening is still recommended. Side Effects of Vaccination Side effects of the HPV vaccine may include: Injection site irritations such as pain, redness, or swelling Fever Systemic reactions such as nausea, muscle pain, malaise, and dizziness Fainting The vaccination is quite safe; different types of the vaccine having been studied in almost 75,000 individuals. These side effects are not commonly experienced, and for most people, it is definitely worth the risk to receive the vaccine than forgo it because of potential mild and temporary side effects.
Feb 01, 2021
4 min read
What to Expect in a Colposcopy Exam

What to Expect in a Colposcopy Exam

Adrienne Hill-Strathy
If you are reading this, you may have recently been referred by your doctor to get a colposcopy. Colposcopies are rarely talked about so can evoke some distress and confusion for patients upon referral. Here we hope to provide some details about the procedure, what to expect, and why it’s a great step to help you get on top of your reproductive health. What Is a Colposcopy Exam? A colposcopy, pronounced kol-POS-kuh-pee, is typically referred to patients following an abnormal Pap smear. Abnormal Paps suggest some cell changes have occurred on the cervix, vagina, or vulva. The device, called a colposcope offers a way to get a closer look at what is going on internally. How Does the Procedure Work? Colposcopies are typically performed by gynecologists. During the exam, you will be asked to remove your clothes from the waist down. Your feet are placed into two stirrups and a speculum is used to view the vagina and cervix. A solution of acetic acid is applied to the area using cotton swabs to make it easier to observe any cellular changes. The acid can burn slightly upon application and may cause slight discomfort. The physician will then move the colposcope into view, depicting an image of the cervix on a digital screen. Many physicians will offer you the option to take a look at the screen, but you can also choose to look away if you wish. Here, the physician can visualize the cervix and observe any changes in color, discharge, irritation, etc. Depending on the observation, the physician may decide to take a swab or biopsy of the cervix for further examination of cell changes. There are two types of biopsies, one taken from the outside of the cervix and another from the inside opening. The biopsy may cause mild discomfort but is generally quick and painless. What Happens Next? Because abnormal cell changes depicted on the cervix will usually be cleared by a healthy immune system within two years, most patients will be asked to monitor the situation by getting a follow up Pap test done every six months. If a biopsy was taken, a follow up appointment will be made to discuss the results, next steps, and if further intervention is warranted. What can you do? Although the procedure and fear of an abnormal Pap test can be anxiety provoking, be proud that you are taking proactive care of your reproductive health. Understanding your risks makes you more prepared to prevent more severe outcomes later in life. Instead of watching and waiting between follow up Pap tests, why not take actionable steps to naturally support your immune system in clearing off the virus? Adopting a healthly lifestyle, diet, implementing stress management techniques and supplementing with products like Papillex, that replenish the nutrients that have been found to be low in people with persistent HPV infections, can effectively help your immune system respond naturally to HPV and leave you in a better state of overall wellness.
Jun 01, 2020
2 min read
Epithelial Cell Abnormality: All You Need To Know

Epithelial Cell Abnormality: All You Need To Know

Christine Chung
You go for your normally scheduled pap test, but this time things are different. You get your test results, and you see ABNORMAL. You, along with 8% of Canada’s female population, are wondering the same thing. What does this mean?  In this blog post, we break down what you need to know about the Pap smear, the possible results, and what it means to have epithelial cell abnormality. First, let’s break down what an epithelial cell is. What is an Epithelial Cell? Epithelial cells are found on the surface layers of the body such as the skin, respiratory tract, urinary tract, and organs. The cells create a barrier between the inside and outside of the body, protecting it from invaders like viruses, bacteria, and other pathogens.  Epithelial tissue is one of the four major tissue groups and can be found lining many parts of the digestive system, the epidermis, the oral cavity, many of the body’s glands, and the cervix. There are three types of epithelial cells: squamous, cuboidal, and columnar. Squamous cells are what we commonly examine when it comes to Pap testing and cell abnormality. Squamous cells are found in the esophagus, mouth, and vagina, protecting the body against wear and abrasion. Different layers of Epithelial Cells What Is An Epithelial Cell Abnormality? An Epithelial Cell Abnormality is when an epithelial cell has undergone abnormal cellular changes, which could indicate cancerous or pre-cancerous cells. When abnormal cells are found on the cervix, this is also known as cervical dysplasia. Epithelial cell abnormality and cervical dysplasia are detected through a Pap test. Normal vs Abnormal Cervix Cells Taken from a Pap Smear What is the Pap Test? The Pap test or Pap smear was invented in the 1920s by a gynecologist named George Papanicolaou. While researching, Papanicolaou discovered certain cellular smears taken from the vagina and cervix and viewed under the microscope differed in epithelial cellular normality. His discovery revealed early detection of cancerous cells in women presenting without any current symptoms. The Pap test has now become part of routine physical examination for individuals with female reproductive parts to detect and monitor the presence of precancerous or cancerous cells on the cervix that may progress into cervical cancer.  The test results from a Pap smear can go one of three ways: NORMAL, UNCLEAR, ABNORMAL. Normal: Indicates no cellular changes or precancerous activity was found. Unclear: Often warrants a repeat Pap test. This indicates that your cells could be mildly abnormal, due to a vaginal or sexually transmitted infection, changes in hormones, or poor test collection. Abnormal: An abnormal Pap test means that some level of cervical cell changes were found. It does not mean that you have cervical cancer but further testing is recommended. Pap Smear Tests Are Essential For Detecting HPV Breaking down the Abnormal Pap Test Results The Pap test is a screening test that reports different grades of abnormality. The following table displays the severity of these results from lowest to highest: Degree of Severity Pap Test Result 0 Normal 1 ASC-US 2 LSIL 3 ASC-H 4 HSIL 5 AIS 6 Squamous Carcinoma Abnormal Result Breakdown Here is a breakdown of abnormal Pap test results: Atypical Squamous Cells of Undetermined Significance (ASC-US) The most common of all abnormal Pap test findings. ASC-US means the squamous cells of the cervix look abnormal. This is likely due to an HPV infection. Usually, the cells return to normal on their own, but your doctor will likely recommend monitoring to be safe. Atypical Glandular Cells (AGC) This type of result is unique from the others listed here as they relate to glandular cells instead of squamous cells. Cervical mucus and mucus in the uterus are produced by these glandular cells. An AGC result indicates that there are abnormalities in the cervix’s glandular cells and raises concerns about pre-cancerous or cancerous cells. Further testing and monitoring will be recommended. Low-grade Squamous Intraepithelial Lesions (LSIL) This indicates mild cervical dysplasia, abnormal tissue potentially signifying early stages of cancerous processes. These changes are likely due to an HPV infection. Often these changes return to normal over time but require monitoring. This could also be known as cervical intraepithelial neoplasia, or CIN 1. Atypical Squamous Cells (ASC-H) Atypical squamous cells are another form of cell abnormality that has a high possibility of being HSIL. Further testing must be completed to know for sure. High-grade Squamous Intraepithelial Lesions (HSIL) This result indicates moderate to severe dysplasia. An HPV infection is present and spreading, causing more serious changes. This is still not cancer, but it has a higher risk of progression into cancer if untreated. With adequate support and treatment, it may go back to normal findings. A CIN 2 or 3 classification would fit here. Adenocarcinoma In Situ (AIS) This finding indicates an advanced lesion was found with a high risk to develop into cancer without proper treatment. This is a stage where it is critical to prevent cervical cancer progression. A CIN 3 classification would fit here. Squamous Carcinoma: A positive screening for squamous carcinoma indicates cancer. Squamous cell cervical cancer makes up 80% of all cervical cancers. At this stage, precancerous cells have progressed to cancer and require further treatment of surgery, radiation, chemotherapy, or other immunotherapies. A diagnosis of squamous is quite rare. Women who receive regular Pap tests will catch cervical cell changes before cancer develops and are very unlikely to ever unknowingly reach this stage. Discuss with your healthcare professional how to proceed following abnormal cell results. What does Cervical Intraepithelial Lesion (CIN) mean? The Pap test cannot tell the exact severity of cervical cellular changes. A cervical biopsy taken through colposcopy is needed to find out whether precancer or cancer is actually present. Cervical biopsy results are reported as Cervical Intraepithelial Lesion (CIN) on a grade of 1, 2, or 3.  CIN 1: indicates mild, low-grade changes in the cells. CIN 1 often will go away on its own without treatment. CIN 2: is used for moderate cellular changes. This is a higher-risk for progression into a pre-cancerous stage.  CIN 3: indicates more severe (high-grade) changes, with a higher likelihood to progress to cancer and may be classified as precancer.   A healthy ldiet and ifestyle helps your immune system Frequently Asked Questions: What is an HPV test?In individuals with abnormal Pap test or females above the age of 30, the Pap test may be combined with an HPV test. The HPV test screens for the presence of the HPV virus, which causes cervical cancer. HPV is very common and can be present without any signs of cervical abnormality. It is often tested to determine which strain of HPV you have contracted. Because some strains have a higher chance of progressing to cancer, knowing the specific strain and viral presence can help your doctor monitor your risk. How often do I need to get a Pap test?Pap smears have now been recommended for sexually active females between the ages 25-69 to be performed once every 3 years. If you have had an abnormal Pap your doctor will repeat your Pap every 6- 12 months until they are clear. What should I do following an abnormal Pap?Following an abnormal result, your primary healthcare provider will refer you for colposcopy. A colposcopy allows for closer examination of the cervix using a microscope. A cervical biopsy may also be taken for more accurate detection of cell types. Read more on what you can expect in a colposcopy appointment.  How are abnormal cervical cells treated?Depending on the severity of cervical abnormality your doctor will recommend monitoring or treatment. Treatment usually includes an excisional and ablative treatment where cervical tissue is removed or destroyed. Loop electrosurgical excision procedure (LEEP) and Conization are the two most common excisional treatments. LEEP uses a thin wire loop that carries an electric current to remove abnormal cells. Conization removes a cone-shaped piece of the cervix that contains abnormal cells. Cryotherapy and laser are the two most common ablative treatments.  How can I naturally support my body to clear HPV?A healthy diet and lifestyle are key to supporting your immune system eradicate the virus. Making lifestyle changes such as eating more fruits and vegetables, exercising daily, sleeping at least 7-8 hours a night, cutting out smoking, and excessive alcohol consumption. By making sustainable changes to support your overall health you will also help your immune system clear HPV. We developed the Papillex supplement for this very reason, to boost your immune system and best prepare your body to regress those abnormal cells back to normal cervical cells. Papillex contains high-quality, fine-tuned ingredients hand-picked specifically to fight HPV infections.
May 15, 2020
6 min read
HPV Awareness Day

HPV Awareness Day

Adrienne Hill-Strathy
Today, March 4th, is International HPV Awareness Day. HPV Awareness Day is all about opening up the conversation around HPV. It’s more common than you may think, and it is not anything to be ashamed about.
Mar 04, 2020
2 min read
HPV Complications Including Genital Warts

HPV Complications Including Genital Warts

Christine Chung
HPV Complications Read below as we cover the WHO, WHAT, WHEN, WHERE, WHY, and HOW of HPV and its complications. The WHO HPV can affect both men and women alike. The rising rates of HPV have been more of a concern for the anatomically female population due to the severe consequence of cervical cancer, 80% of which have been attributed to an HPV infection. Severe cancer-linked complications in men are rarer than that of women, which is why prevention and treatment have been heavily focused on women. Most men have no symptoms, so the diagnosis of HPV is quite difficult. It can only be made when external genital warts are seen. Grade school boys are now being included in a school-based mandate to vaccinate against HPV to decrease transmission. The WHAT HPV causes a number of lower risk and higher risk complications to the body. These include: Common warts Genital warts Plantar warts Facial warts Pre-cancerous lesions of cervix, anus, penis, vulva, or uterus Cervical cancer Penile carcinoma The diseases caused by HPV may lead to certain secondary conditions or disorders. These are termed HPV complications. Most HPV viruses do not cause any serious complications, as the infections are self-limiting and regress spontaneously within a period of 1 to 2 years in about 90 percent of patients. Only a small number of people suffer from persistent HPV infections and have an increased risk of developing cancer. HPV can feel isolating, but don't worry, you're not alone HPV complications include: Cancer: Persistent HPV infections caused by high-risk types, mainly type 16 and 18, may progress into malignancies. Cervical Carcinoma (the most common complication associated with malignancies) Genital Carcinoma Vulvar Carcinoma Anal Carcinoma Penile Carcinoma (rare cancer associated with HPV) Genital warts in the urinary tract may become enlarged leading to difficulties in urination. In pregnancy, warts on the vaginal wall may lead to obstruction during vaginal delivery. Genital warts may become ulcers or open sores. Ulcers can lead to infections of the rectum, anus, urethra, and even mouth or throat. Warts in the throat, or laryngeal papillomatosis can occur in newborns, from delivery when born to through vaginal delivery to women with warts. This rare condition requires urgent attention. The WHEN HPV has an estimated incubation period from HPV infection to genital wart development anywhere from 2 weeks to 8 months. The majority of genital warts appear 2 to 3 months after infection. Most people clear an HPV infection naturally with a healthy immune system in 1 to 2 years. Some people may stay infected for years. It will take about 10 to 30 years from the time of infection to see a cancerous tumor form. It is important to get routine checkups and pap tests to stop the cervical cell changes in their path before they progress further into cancer. The WHERE Complications most likely arise in the genital, anal, and oral areas of both men and women. HPV mostly affects a woman’s cervix, causing cervical dysplasia and abnormal cell changes that may lead to cancer if untreated. The WHY There are over 150 different known strains of HPV. Some of these are high risk and some are low risk. About 14 of these strains are specifically linked to higher rates of cancer and are termed “high risk”. We need to support each other through illnesses like HPV HPV 6 and 11 cause 90% of genital warts linked to HPV, but are considered “low risk” strains because they rarely develop into cancer. HPV 16 and 18 cause an estimated 70% of all cervical cancers. These two strains are widely known as the highest risk strains of HPV. The HOW HPV is easily spread from sexual skin-to-skin contact with a partner who has HPV. You can get it when your vulva, vagina, cervix, penis, or anus touches someone else’s affected area, genitals, mouth, or throat. This can occur during sex, including oral and anal sex. It can spread even if there is no ejaculation. It is possible that open-mouthed kissing with a partner who has an oral HPV infection may cause transmission, but the jury is still out on that one. What Now? If you're concerned about HPV, you can learn more about HPV testing in our in-depth article. If you want a way to respond naturally to HPV, why not check out our product, Papillex?
Feb 05, 2020
3 min read
Recover From An Abnormal Pap Smear. Fast.

Recover From An Abnormal Pap Smear. Fast.

Christine Chung
Watch and Wait…or Take Action? How One Doctor Supports Patients to Recover Faster from an Abnormal Pap Smear To celebrate Cervical Cancer Awareness Month, Dr. Amy Kroeker, ND shares her perspective on managing abnormal Paps, and shares a remarkable case of cervical dysplasia that has a happy ending. If you have ever had an abnormal Pap and heard this phrase, you’re not alone. And, if you are anything like me, you don’t like waiting. Cervical dysplasia is caused by the HPV virus which causes normal cervical cells to change form into abnormal cells prone to becoming precancerous or cancerous cells. It is standard medical advice to “watch and wait” when first diagnosed with an abnormal PAP (ie. cervical dysplasia). However, what exactly are we waiting for…and what are we watching? It’s not like we can see our own cervix to check up on it. In my practice, I’ve always found this advice to be excruciating to the female psyche. For 6 months, women are asked to wait, and then the PAP is re-done to see if the cells have converted back to normal cells or continued to progress towards abnormal pre-cancerous or cancerous cells. It is assumed that since the abnormal cells are caused by a virus, that your body may be able to fight the virus off in this amount of time and allow the cells to heal. If they do not, then treatment (often by laser) is required. But wait, if these cells are caused by a virus, isn’t there more we can do to help our bodies fight this virus off? Aren’t there a lot of natural remedies that can help boost our immune systems? Case Study of a 26 year-old female A few years ago, I had a patient with a memorable case of HPV-induced cervical dysplasia. A 26-year-old woman who wanted to boost her own body’s immune system to reverse the abnormal cells. Her gynecologist gave her 6 weeks before doing a laser removal of the cells. At the time, I thought it wouldn’t work. Natural medicine is all about focusing on prevention and I didn’t believe we could reverse abnormal cells in that time frame. I made sure my patient knew there were risks to waiting but since her gynecologist had agreed to wait 6 more weeks, and she was determined to use those 6 weeks to their full advantage, I did some research and came up with a plan to support her own body’s immune system with diet, vitamins, and anti-viral and hormone balancing nutrients. What was the result? A clean PAP. That case, and the research I did for it became my protocol to give women back control during the “watch and wait” phase. I don’t suggest ever delaying treatment once needed and recommended by your doctor or gynecologist but during the “watch and wait” phase I prefer to take action to provide an environment supportive of the best possible outcome. The following are some of the tips I recommend to help boost the immune system while waiting: #1: Diet Emphasize eating vegetables and fruits (at least 7-10 servings per day) to boost antioxidants and increase immune system function. Research shows that high levels of vegetable consumption are associated with a 54% decrease in HPV persistence. Specifically, consume at least one serving per day of a cruciferous vegetable such as broccoli, kale, cauliflower, or Brussel sprouts and at least one serving of dark green leafy vegetables or bright orange/red vegetables at every meal. There are lower rates of HPV infections reported among women with higher intake of carotenes, lutein, zeaxanthin, and vitamin C, and these vitamins and antioxidants are found in brightly colored vegetables and fruits. Lignans, a nutrient found in high concentrations in ground flaxseeds, help to lower levels of free estrogen in circulation. Consuming 2 tbsp per day can help improve the hormone balance necessary for the ovaries, uterus, and cervix to function optimally. As for what foods to avoid; avoid processed foods, foods with added sugar, alcohol, and coffee. These foods create unnecessary stress on the body and hormonal systems and we need to create space in the diet for more nutrient dense foods. #2: Supplements There are a lot of different nutrients with research showing they help the immune system or help the body fight viruses like HPV. These supplements are individualized for each patient so I always recommend working with a licensed naturopathic doctor or functional medicine doctor to tailor a program specific to you. However, I consider the following nutrients since they have the most research. Folic acid – ideally in the active form Vitamin C – higher doses, if possible, from food or supplements Vitamin A – higher doses but if you go above 10,000 IU daily then you need to work with a doctor for liver safety I also like to use a product that contains reishi mushroom, mixed carotenoids, broccoli sprout extract or DIM, and green tea extract – these are all found in the supplement Papillex. I have yet to find a better blend of ingredients combined in one formula for the support of cervical dysplasia. So, next time you are told to “watch and wait” after an abnormal PAP, seek out a licensed naturopathic doctor or functional medicine doctor so you can support your body while it tries to heal and repair from the HPV virus. Why feel helpless while waiting? Take action! Dr. Amy Kroeker, ND practices from her clinic in Winnipeg, Canada. Learn more about Amy at https://www.amykroekernd.com/about
Jan 22, 2020
4 min read
Staying Positive While HPV Positive

Staying Positive While HPV Positive

Christine Chung
I’m HPV positive…what do I do now? This is a thought on the mind of many people who get diagnosed with HPV. With the risks for cervical cancer and other complications, the future may seem grey. Most people feel a fear of judgment from anyone who may find out, causing them to keep their diagnosis hidden. This can create a cascade of events surrounding a negative outlook. What you may not know is that HPV is more common than you think, and technology has come a long way to bring a bright future. Is HPV as Scary as It Seems? Reading material on the topic of HPV can be overwhelming, intimidating, and scary, especially with all the misinformation and stigma out there. The truth is, most sexually active people are likely to have been exposed to HPV at some point in their lives. It can occur through any sexual contact: skin to skin contact, oral sex, anal sex included. What about my cancer risk? Not all HPV infections will cause cancer. In fact, only a few out of the 100+ strains of HPV known cause cancer. Most of the time with a robust immune system, your body is able to clear these infections without any symptoms! With routine screening, your doctor has caught your HPV progression and will take measures to prevent cancer from occurring. Positively Affecting Your Immune System Your immune system is key when fighting HPV. One aspect that can truly impact your outcome, is your mindset. Happiness and positivity has been shown to reduce stress and promote healthier lifestyle habits, all of which will help boost your immune system. Did you know that positive individuals were shown to be more likely to consume fruits and vegetables? This is all connected by your HPA axis that regulates your happy hormones and your immune system, among other bodily functions. Positive people sleep better, get sick less, exercise more, stress less, eat better…and much more! Where Do I Begin? Sharing your experience with those close to you may help build your support team to help you stay positive. Disclosing your HPV status to your sexual partner, family, or friends can be a supportive and affirmative experience. There are also support groups available where you can share your experiences and others may understand on a deeper level.  Educating people is one way of actively breaking the stigma associated with sexually-transmitted infections, which is crucial to helping people establish safe sex practices, including those around oral sex. No matter what happens, take comfort in making brave, compassionate and honest choices. If you plan on having that conversation with your partner, you don’t need to be scared. There is so much support available around this subject. Check out our blog on How to Talk to Your Partner about your HPV Status for some tips. How else can you support your body naturally? Most HPV infections are easily cleared by a strong, healthy immune system. Your immune system can be supported in a number of natural ways: Eat plenty of fruits and vegetables Quit smoking Reduce alcohol consumption Drink green tea Exercise to sweat Papillex™, is a clinically-researched, nutrient-rich supplement designed to increase your body’s ability to respond to HPV naturally. By optimizing your natural immunity and replacing missing and low nutrients, Papillex™ helps you to create an environment inhospitable to HPV and its common symptoms, cervical dysplasia and genital warts.
Nov 20, 2019
3 min read

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