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The Role of Nutrition in Cervical Dysplasia

The Role of Nutrition in Cervical Dysplasia

Victoria Gasparini
Cervical dysplasia, characterized by abnormal changes in the cells of the cervix, is a condition that can potentially progress to cervical cancer if left untreated. Medical interventions such as colposcopy and even the "watch and wait" method, are common when diagnosed with dysplasia of the cervix, but there's an additional step we can take to help manage this, reducing our long term risk for cervical cancer and enhancing our health and well-being on all levels. At Papillex®, we have consistently emphasized the notion that merely "watching and waiting" for our health to deteriorate before taking action is insufficient. Our conviction is well-supported by compelling data. The abundance of evidence linking nutrition to cervical health and dysplasia suggests that it could very well be the intervention you've been looking for. Nutrition principles to follow Emphasize the use of antioxidant-rich foods Antioxidants are powerful compounds that help protect our cells from damage caused by free radicals. Studies suggest that oxidative stress may play a role in the development and progression of cervical dysplasia. Including antioxidant rich foods in your diet can help combat oxidative stress and support cervical health. Colorful fruits and veggies, like berries, citrus fruits, dark leafy greens, bright bell peppers, eggplant and tomatoes are all excellent sources of antioxidants. Increase intake of folate and other B vitamins Folate, along with other B vitamins like B6 and B12, are crucial for DNA synthesis and repair. Research suggests that low levels of folate may be associated with an increased risk of cervical dysplasia. Incorporating folate-rich foods such as leafy greens, legumes, citrus fruits, and fortified grains can help ensure adequate intake. Additionally, a balanced diet that includes lean meats and fish, with moderate amounts of dairy (if tolerated) can help provide these essential nutrients, as well. Up your Vitamin C Vitamin C is another crucial nutrient for immune function and collagen synthesis. Studies have shown that higher vitamin C levels are associated with a lower risk of cervical dysplasia and progression to cervical cancer. Citrus fruits, strawberries, kiwi, bell peppers, and broccoli are all excellent sources of vitamin C that can all be easily incorporated into your daily meals. Get those healthy fats in Incorporating healthy fats into your diet is essential in hormone regulation and overall health. Opt for sources such as avocados, nuts, seeds, fatty fish and olive oil. These fats provide important nutrients and contribute to a well-rounded and nourishing diet. Reduce your intake of saturated and trans fats as these tend to be more inflammatory. If you're thirsty, you're already dehydrated! Proper hydration is vital for overall health, including cervical health. Drinking an adequate amount of water helps maintain optimal cell function and supports the body's natural detoxification processes. Non-sugary electrolyte beverages can also help you achieve a more robust amount of minerals. Aim for at least eight glasses of water per day and reduce consumption of sugary beverages.
Aug 07, 2023
2 min read
The 5 Steps to Healing HPV

The 5 Steps to Healing HPV

Victoria Gasparini
If you have received an HPV diagnosis from your healthcare provider, you are probably feeling a little lost, frustrated and maybe even overwhelmed with what to do next. Unfortunately, all too often, women are told their next steps are to “watch and wait” for HPV to either progress or stay the same, consistently affecting you as a patient, and leaving you disempowered in this diagnosis. The truth is, the unknown of an HPV diagnosis which can range from completely mild to severe, is really a scary thing to go through on your own.  With that being said, nearly 80% of the population has HPV. Cervical cancer affects about 12,000 women in the United States each year, and other HPV-related cancers such as anal and oropharyngeal are rising too. Though most cases of HPV are mild, benign and even self-resolving, hundreds of thousands of women will be told they have an abnormal pap each year. Doesn’t this feel like something we should be talking about? Doesn’t this seem like a diagnosis that should be taken seriously, with action plans and clinical guidelines to help people with HPV reduce their likelihood for complications? At Papillex®, watching and waiting is simply not good enough for us. So what are some actions you can take to address HPV? Keep reading to find out. There are five key considerations we have when it comes to clearing and healing HPV and cervical dysplasia, and reducing your risk for HPV-related cancers.  Consider Nutrient Deficiencies When many of us think of the health benefits of food, proteins, fats and carbohydrates come to mind. These macronutrients make up the general composition of our foods but within them lie additional health-promoting compounds called micronutrients. Micronutrients include trace minerals and vitamins that support the normal growth and development of living organisms. Without them, body systems like the immune system, nervous system, and digestive system can become impaired. Many individuals are deficient in micronutrients. This can be due to low intake of dietary sources like fruits and vegetables and high intake of processed and nutrient-poor foods. Additionally, it is thought that the micronutrient quality of our fresh food has declined in recent years due to industrial agricultural production. This micronutrient deficiency may be at the root of why some people struggle to eradicate HPV infections compared to others who clear the virus more easily. Several micronutrients have been specifically found to be low in individuals with HPV and cervical dysplasia. The most common micronutrient deficiencies associated with HPV include folate, vitamin A, selenium, vitamin C and vitamin E. For more info on these micronutrients and how to correct deficiencies, click here. Consider Inflammation We know that the immune system is a key factor in regressing HPV infections. Studies have found inflammatory molecules assist the virus to integrate and proliferate into an individual’s tissues. This means that the more inflammation present, the easier it is for viruses to infect our tissues. Inflammation leaves our cells more vulnerable to further damage. HPV itself also drives inflammation. The viral particles produced by the HPV (E6, and E7) are also inflammatory and drive more inflammation which further decreases the level of antioxidants, our main weapons against oxidative damage. Together these processes allow HPV to persist. For more information on how inflammation affects HPV and what to do to control it, click here. Consider the Vaginal Microbiome The vagina is an incredible organ with a protective epithelium and diverse microbial ecosystem. The vaginal tract is rich in all sorts of “commensals”, meaning microbes that are non-harmful and even beneficial for the vagina and our health. The largest species of microbes in the vaginal tract are called lactobacillus, which you may have heard of if you take oral probiotics. Any potentially harmful microbes in the vagina are kept at bay by our unique acidic pH.  Stress is a major disrupter of this microbial balance. Since stress itself is inevitable, cortisol (our fight or flight hormone) has the capacity to disrupt the vaginal microbiome and its ability to fight infections of the genitourinary tract. Researchers from the University of Illinois have even found a potential link between pandemic-related stress and the increase in STI’s amongst young women. The data from this small, but fascinating study found that young women who reported higher levels of pandemic-related stressors also had increased odds of infection. Professor of epidemiology and biostatistics, Mehta, suggests that the uptick in stress-related infections is likely due to changes that occur in the vaginal microbiome during times of chronic stress. This study sheds light on the impact of environment & psychosocial factors on our physical health, as women. Another study in the Frontiers of Endocrinology found that exposure to chronic stress led to a significant decrease in lactobacillus microbes in the vaginal tract. As mentioned above, the lactobacillus species is one of the most significant “commensals” in the vagina, providing us with protection against invaders and therefore amplifying both the severity and frequency of vaginal infection. For more information of supporting a healthy vaginal microbiome, click here. Consider Blood Sugar Balance research finds that glucose spikes and insulin resistance both contribute to malfunctioning immunity and the inability to effectively fight off infections.  One study found that glucose spikes inhibited microbial killing and phagocytosis, as well as increased the production of inflammatory cytokines in otherwise healthy subjects. Trials continue to show that by managing glucose spikes, we can reduce susceptibility to infection and allow us to create healthy immune responses to infections when necessary. Because HPV is a viral infection, supporting the immune system’s ability to fight infections is the most important effort you can make when healing with HPV.  Many lifestyle and dietary habits can be contributing to glucose spikes. As mentioned above, simple carbohydrates on their own, like a bowl of cereal, coffee drinks on an empty stomach, dried or juiced fruits, and other high-sugar foods all contribute to glucose spikes and the susceptibility to insulin resistance seen in diabetics and patients with polycystic ovary syndrome (PCOS). But it is not just diet that leaves us vulnerable to glucose spikes. PMS, lack of sleep, and genetics all play a role in our susceptibility to glucose spikes and insulin resistance as well. Aside from not being able to change or control your genetics, there are many dietary and lifestyle changes (surprisingly some pretty easy ones, too) that can lessen these spikes and thereby reduce your symptoms. For simple tips to help manage your blood sugar, click here. Consider your support system Healing and dealing with a diagnosis like HPV, whether mild or high risk, is a scary and frustrating place to be. You don’t have to do it alone. In fact studies find that a proper support system is crucial in healing all sorts of infections and chronic conditions. Whether you find your support system in your family, friendship groups, care providers or internet besties (us!), this is a consideration that cannot be skipped. At Papillex®, we are here to support you on this incredibly empowering journey to healing HPV. Feel free to share your story with us on instagram, or just send a hello to chat! We are here for you.
Mar 06, 2023
5 min read
5 Steps to a Healthier "Down There"

5 Steps to a Healthier "Down There"

Victoria Gasparini
Many of us have come to accept that womens health issues such as dryness, infections, cervical dysplasia and pain in the vaginal canal are all normal parts of being a female. But what if I told you this does not have to be your reality? There is a great deal you can do to control and prevent vaginal infections, make intercourse and sexual experiences less or not painful at all, and even heal and prevent cervical dysplasia. Some issues commonly experienced by women are, vulvovaginitis, vaginismus, bacterial vaginosis, and yeast infections. Women may also experience cervical dysplasia caused by HPV, and gential lesions from HSV.  Because the above issues are so common in society, they are rarely taken seriously in the medical community, but for most of us women, they do impact our quality of life and our ability to be our true authentic selves.  Here are 5 steps to a healthier “down there”  Lifestyle Oral contraceptive use Many women rely on oral contraceptives for a variety of hormonal-related issues, as well as for contraception. While the pill is an important part of many of our personal lives, there are some negative implications to our vaginal and cervical health that come with taking them. For example, oral contraceptives that contain estrogens can increase incidence of yeast infections. Additionally, oral contraceptives increase your risk for worsening HPV-related symptoms. Though the research is still blurry when it comes to how birth control can increase cervical cancer risk, we do know that taking oral contraceptives depletes many key nutrients that are required to help us keep our HPV inactive. The pill can deplete riboflavin, vitamin B6, folic acid, vitamin C, and zinc. We know these nutrients are important players in supporting the immune system and some have even been specifically linked to HPV. Moreover, the birth control pill is also known to alter the gut microbiome. The pill may increase leaky gut, dysbiosis, and candida overgrowth. A healthy gut is another foundation for our immune and overall health. Impairing this system can have a widespread impact on the rest of the body. Finally, certain types of birth control pills can affect your sex drive, impacting your intimacy, sexual health and ability to feel lubricated.  Vaginal ecology disruptors Antibiotics, sanitary products like tampons and pads, and steroid-use can all impact our vaginal health and microflora. The good news is we can reduce or avoid these environmental triggers. Antibiotics, while incredibly necessary and helpful when needed, can do immense damage to the vaginal microbiome. By keeping our immune system healthy (by using the tips from our blogs), you can hopefully prevent chronic infections that require antibiotics.  Sanitary pads and tampons typically contain harmful ingredients such as bleach, and can be avoided by purchasing organic 100% cotton ones, or switching to a menstrual cup or menstrual underwear. Never, ever douche. It’s 2023, let’s stop trying to convince women that their vagina’s should smell like flowers. Our vaginas are self-cleaning machines. All you need is water or a gentle soap on the vulva area (the area surrounding the vagina), and that is it. In fact douching your vagina changes the pH and can actually result in more infections and even a foul smell down the line. Safe sex is enjoyable sex We are all for practicing safe sex as a way to reduce viral transmission, the incidence of BV and UTI’s but also to prevent unwanted pregnancies. However, typical latex condoms and chemical laden lubes might be the sneaky reason behind your vaginal infections that seem to pop up every time you get intimate.  Skip the traditional brands and go natural where possible. Many lubes and condom companies are now offering “spermacide-free” condoms, and chemical-free lubes. Typical lubes can disrupt the vaginal flora and pH leaving us at a higher risk of developing vaginal infections.  Food Food truly is medicine, and can help us prevent and handle all kinds of women's health issues. Phytonutrients can help us with healthy vaginal tissue, lacto-fermented foods can help nourish our microflora, and balancing our blood sugar can help support vaginal ecology while also preventing recurrent HPV related flare-ups. Though I know it can be tempting to reach for the bottle of wine after a long day of work, we recommend skipping that glass when possible and opting for a sparkling water, or alcohol-free, low sugar option. Herbs & Nutrients Supplementation can be incredibly individual, however, Papillex was made with the intention of correcting the most common nutrient deficiencies found in women with HPV. These nutrients like folate, green tea extract and vitamin C have all been found to be extremely beneficial in women's and general health, too. We also really like to add an omega 3 to our routine for reducing inflammation, and inhibiting the growth of HPV cervical cells. Finally, AHCC has been shown to clear even high-risk strains of HPV after several months of use. Talk to your health provider about what supplementation is right for you. Mind-body connection When it comes to starting your holistic healing journey, we believe the best approach includes a strong mind-body connection. More and more studies are finding a link between past traumas, adverse childhood events, and high levels of stress with vaginal infections and conditions like vaginismus. Dealing with these issues is likely the hardest but most important part of true healing. If you had the chance to tune in to our instagram LIVE last week with women's integrative health coach, Denell (@cervicalwellness) and founder of Papillex, @drgoldspink, they had an incredible and inspiring conversation about the psycho-emotional aspect of healing conditions like HPV and cervical dysplasia. If you did not get a chance to see it, head to our instagram this week to check it out. Therapy We are big advocates for talking it out. Therapy, a good partner, good friendships, online or in-person support groups, a good primary care provider, naturopathic doctor, pelvic floor therapist or healer of any kind can really help you with these intense but important breakthroughs that can hopefully kickstart your healing from all sorts of problems we see happening “down there”. Sadly, there is a stigma around many of these conditions, so much so that I had to avoid using the term "vagina" in the title of this blog post. It's time we start talking about these issues that so many of us face. Interested in more tips of healing vaginal infections, cervical dysplasia, HPV and/or HSV? Follow us on instagram to continue the conversation.
Feb 06, 2023
5 min read
Stress and Vaginal Infections: What's the Link?

Stress and Vaginal Infections: What's the Link?

Victoria Gasparini
Stress is a normal part of our lives, and our bodies are made to handle these stressors through a tightly regulated hormonal system. Hormones that are involved in stress include adrenaline, epinephrine, norepinephrine and cortisol, to name a few. We rely on these hormones to protect us against the impact of physical and emotional stressors, and without this system we, nor our ancestors, would have ever made it this far.  The impact of stress is widely recognized in medicine, but it isn’t actually stress itself that is the problem. In today’s day and age, it’s the everyday, low level stressors that are having the most impact on our health. Chronic stress is the silent killer.  In the olden days, true stress was usually a result of two things: widespread famine and/or being chased down by a wild animal. In these crucial moments, our ancestors' hormonal system adapted to stressors like these by producing mass amounts of stress hormones, adrenaline, epinephrine and cortisol. This temporary surge of hormones allowed us to store excess fat around the belly (in times of famine), shut down reproductive function (because who wants to get pregnant when there’s not enough food available?), and to run extra fast to escape that wild animal. The production of stress hormones is a survival mechanism that is adaptive to the stressors of the time. Cortisol, otherwise known as the “fight or flight” hormone, is the main driver. But we don’t have the same problems as our ancestors anymore. Now, our society works 9-5, sits in traffic for several hours, and deals with much more minor stressors than our ancestors did. It's this low level, chronic stress that is wreaking havoc on our society, our microbiome, and the chronic disease epidemic as a whole. The vaginal microbiome: how chronic stress impacts the vagina and your overall health The vagina is an incredible organ with a protective epithelium and diverse microbial ecosystem. The vaginal tract is rich in all sorts of “commensals'', meaning microbes that are non-harmful and even beneficial for the vagina and our health. The largest species of microbes in the vaginal tract are called lactobacillus, which you may have heard of if you take oral probiotics. Any potentially harmful microbes in the vagina are kept at bay by our unique acidic pH. So, how does chronic stress throw this strictly regulated system out of balance? Science suggests that cortisol inhibits vaginal glycogen deposition which then leads to infection. Our estrogen production as females increases the vaginal glycogen & epithelial maturation that is necessary to maintain adequate vaginal health. Chronic production of cortisol disrupts this important process. What can you do?  Since stress itself is inevitable, cortisol has the capacity to disrupt the vaginal microbiome and its ability to fight infections of the genitourinary tract. Researchers from the University of Illinois have even found a potential link between pandemic-related stress and the increase in STI’s amongst young women. The data from this small, but fascinating study found that young women who reported higher levels of pandemic-related stressors also had increased odds of infection. Professor of epidemiology and biostatistics, Mehta, suggests that the uptick in stress-related infections is likely due to changes that occur in the vaginal microbiome during times of chronic stress. This study sheds light on the impact of environment & psychosocial factors on our physical health, as women. Another study in the Frontiers of Endocrinology found that exposure to chronic stress led to a significant decrease in lactobacillus microbes in the vaginal tract. As mentioned above, the lactobacillus species is one of the most significant “commensals” in the vagina, providing us with protection against invaders and therefore amplifying both the severity and frequency of vaginal infection. In addition to infection, women can actually experience decreased libido and increased vaginal dryness as a result of cortisol suppressing sex hormones like testosterone. Do you see how important it is for us to get a handle on our stressors? But how? Handling stress in stressful times Address nutrient deficiencies Did you know, it's not just mental and emotional stress that increases susceptibility to infection? Nutrient deficiencies are a significant physical stressor on our body and lead to a suppression of immunity and therefore an increase in infections, like HPV and bacterial vaginosis. Taking your daily dose of Papillex is a wonderful, evidence-based way to correct some of the most important and prevalent nutrient deficiencies in our community. Try therapy Sometimes stressors are rooted in childhood or other areas of our lives that we may need help exploring with a professional. Therapy can help you uncover some of the root causes of your vaginal infections, and address the stress that is potentially causing them. Because women's health research still lacks in many areas, we do not currently know the exact link between trauma and vaginal-related infections, but more and more research is pointing us in that direction. There is no shame in therapy. It might just be the step you need to take to move your healing journey in the right direction. Protect the immune system Once you have addressed nutrient deficiencies and the root of your stress, adaptogenic herbs and mushrooms are an incredible addition to your healing. We love to use herbs like Ashwagandha, which has been shown in studies to not only reduce the impact of stress on the body but also reduce our actual perception of the stressor that is occurring. Additionally, mushrooms like AHCC have been used in traditional medicine for centuries to help combat a wide variety of infections, and have recently been studied for clearing high-risk HPV. A combination of herbs and mushrooms, unique to your physiology, can be a crucial addition to your treatment plan. Check out our instagram for more tips on healing HPV.
Jan 02, 2023
4 min read
So, You've Had an Abnormal Pap, Now What?

So, You've Had an Abnormal Pap, Now What?

Victoria Gasparini
In 2022, an estimated 14,100 women in the United States have been or will be diagnosed with cervical cancer, caused by HPV. In 2020, over 600,000 women were diagnosed across the globe. While the HPV vaccine has drastically reduced cervical cancer rates as a direct result of preventing high-risk HPV, there are still approximately 4300 deaths per year in the United States alone, from cervical cancer. Take comfort knowing that most HPV cases do not cause cancer, and that many strains of HPV can be controlled and suppressed naturally by supporting the body’s immune system and encouraging adequate viral clearance. The high risk strains of HPV are 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 66 and 68. HPV 16 and 18 are typically the higher risk types and are responsible for most types of HPV-related cancers.  What to do after receiving an abnormal pap smear The Pap smear involves taking a cell sample of the cervix and assessing for any abnormalities. By monitoring cell changes, earlier treatment and interventions can be implemented which can prevent more severe disease. If you receive an abnormal pap smear result, it is best to talk to your doctor about what your next steps are. This may include more frequent screenings, among other possible solutions. Unfortunately, from a conventional standpoint, the advice is typically to “watch and wait” at this point in the diagnosis.  Fortunately, more and more research is finding that there are ways to control and manage HPV naturally, with dietary and lifestyle changes. Let’s dive into your post-diagnosis plan, below.  First things first, know that you aren’t alone.  HPV is one of the most common sexually transmitted infections, affecting 80% of sexually active women. In fact, most sexually active men and women will contract some strain of HPV at some point in their lives. It is not uncommon to have an abnormal pap smear during routine testing. It is, however, important to do what you can to get HPV under control.  Talk to your doctor about follow-ups, strains and risk. While Pap testing and increased screening have resulted in a decline in cervical complications, there remains some debate over how often early screening should take place. Considering 90 percent of HPV infections will regress over time, screening can also lead to harm such as unnecessary stress on the individual, additional follow-up testing and biopsy, and the potential of unnecessary treatment.  The chances of having an abnormal Pap smear are higher in young individuals and decrease with age. Around 10% of individuals with a cervix aged 20-29 years will have an abnormal test result while only 1.6% of those aged 60-69. Of these abnormal results, 1.5% of 20–29-year-olds will have high-grade lesions that lead to further testing and biopsy. However, more than 50% of these will undergo treatment. Many of these infections would clear on their own and lead to no complication of cervical cancer. Depending on where you live and your unique, individual case - your screening guidelines may differ. It is best to work with your physician to develop a plan that is right for you. Find out the screening guidelines in your country here.  Adopt a healthy immunity plan.  At Papillex, we dive into the research on building your immune system to help prevent and clear infections like HPV. Here are some of our favorite, evidence-based tips for building and adopting a healthy immunity plan to help you take control of HPV.  Find movement that you enjoy  Consistency is key when it comes to exercise and movement - so if it does not come naturally, know that you probably won’t stick with it. Try finding a daily movement you enjoy such as walking outdoors, weight lifting, kayaking, swimming, hiking, rock climbing - anything that gets you up and going.  Eat a wide array of colorful vegetables and fruits. The more variety you consume with regards to veggies and fruits, the better. Nutrients like carotenoids, sulforaphane, folate, vitamin C, selenium and more, have all been shown to boost immunity and increase clearance of HPV.  While all foods are welcome in a healthy, balanced diet, it is best to focus on anti-inflammatory, antioxidant and phytonutrient-rich foods, with limited intake of starches and sugars. You can find out more about diet and HPV here.  Practice mindfulness  Addressing stressors in our lives is often the biggest barrier to healing, and also often the most important barrier to knock down. The connection between stress and persistent infections is clear which is what makes mindfulness such an integral part of your healing. Studies continuously find a connection between stress and its impact on immunity, which is supported in pathogenesis and persistence of HPV infections. You cannot always control stressful events from occurring, but you can manage perceived stress through methods of talk therapy, finding good friends to chat with, getting adequate sleep and nutrients, and getting outside in nature. Reducing perceived stressors can help with HPV disease management and progression and is an important part of any HPV treatment plan. Other things you can do to manage stress include, positive self-talk and reinforcement, surrounding yourself with positive people, trying acupuncture and/or massage, and more. Click here for more stress-management tips.  The most important thing you can do for yourself after receiving an abnormal pap smear, is to be gentle with yourself. HPV is not your fault. It is a virus that can be managed and controlled. Holding onto shame can prevent us from living a healthy life, and can contribute to stress and unhealthy behaviors that impair our immune system. Letting go of the shame associated with HPV may be foundational to our healing. Be kind to yourself. For more tips on managing HPV, follow us on instagram @papillex.
Aug 22, 2022
4 min read
Getting Creative: Can We Detect HPV In Sanitary Pads?

Getting Creative: Can We Detect HPV In Sanitary Pads?

Victoria Gasparini
In the United States, among other countries, we have a growing public health dilemma. People are not showing up to their regular pap screenings. Because of this, an alarming 52% of cervical cancers are detected in advanced stages. Because early detection of cervical cancer cells via pap smear significantly decreases risk of fatality, detecting cervical cancers in advanced stages is putting us at not only a tragic and incomprehensible disadvantage for fighting disease, but also a preventable one.  But, it's not as simple as reminding our friends and families to head to the doctor. In the United States, we have disparities comparable to lower income nations - preventing Americans from attending their regular screenings, such as income, location and other social determinants. In fact, some research suggests your zip code has more impact on your health outcomes, than any other factors.  Because of this, public health experts have to get creative in finding ways to detect HPV that are cheap and effective, and don’t require the same kind of testing that is currently available, albeit inaccessible to some. Are sanitary pads the cheap and effective solution to this public health dilemma? Maybe. A 2003, small study with 17 participants found that 100% of cervical cancer participants had HPV detected in their menstrual pads. After this study, little was done with this information in the United States. However, in India, where access to pap smears is much less available - they’ve begun using sanitary pads as a way of detecting HPV and cervical cancer risk.  In the world's first trial of its kind, women in the community-based study are packaging up used sanitary pads, and shipping them on dry ice to the National Institute of Research in Reproductive and Child Health Laboratory in Mumbai, India to test for HPV. Another group of researchers in China, took used menstrual pads and were able to successfully identify HPV in 94.2% of them. In fact according to the Washington Post, the DNA analysis used on these menstrual pads was more accurate in identifying HPV and multi-strain cervical cancers than other cervical tests available. Does this replace the need for pap smears? Not yet, at least. Despite our best efforts, HPV is still a heavily stigmatized infection. Additionally, some patients find cervical screenings to be invasive and uncomfortable. Public health experts have to adopt out-of-the-box thinking when it comes to preventing advanced cervical cancers, and promoting HPV screening to the public. HPV screening via sanitary pads may be an innovative and less invasive way to encourage others to maintain regular screenings. However, because this approach is not currently practiced throughout the United States, it does not replace the need for regular pap smears. Not yet, at least. What do you think? Send me a DM on instagram to chat!
Aug 08, 2022
2 min read

HPV: 5 Things Every Woman Should Know

Victoria Gasparini
An HPV diagnosis can leave one feeling vulnerable, scared, overwhelmed and even ashamed. So when you take to google to find stories of others dealing with HPV, it can be disappointing to realize that there are not many resources associated with empowering, educating and empathizing with others going through a similar experience.  At Papillex, our goal is to be that voice. We want to ensure that you have access to informative content, quality supplements, and act as a sounding board for those with HPV (and HSV, too!). Below are 5 things we believe every woman should know about their HPV diagnosis.  HPV is common and nothing to be ashamed of Dr. Brene Brown defines shame as an “intensely painful feeling or experience of believing that we are flawed and unworthy of love and belonging”. To break through the barriers built by shame, one must be vulnerable. Vulnerability has the ability to transform fear and shame into belonging and acceptance.  HPV is nothing to be ashamed of. In fact, nearly 80% of people will have HPV at some point in their lives. However, because HPV is a sexually transmitted infection, there tends to be a stigma that prevents many from talking about the condition. Because of the shame many women feel, it can be tough to find support in our peers as it is not widely talked about. HPV is a virus. Viruses spread. This is a normal part of life, and the more we talk about it, the less shame and stigma we attach to it. Discussing and spreading awareness of HPV takes great vulnerability, but it also brings a sense of belonging to you and those around you going through the same thing. Having HPV does not mean you will get cancer. There are nearly 150 strains of HPV, with about 12 of them being linked to cervical cancer. Having HPV does not mean you will have cervical cancer, but it is important to be aware of your condition and keep up with regular screening, as well as lifestyle and dietary management to prevent disease progression. Talk to your doctor about vaccination, and remember to always practice safe sex by using protection like condoms or dental dams. Though these are not fool-proof, they do help to decrease the chances of transmission. A great practice is to strengthen your immune system through science-backed lifestyle changes like adequate sleep, increased consumption of antioxidant rich foods and powerful supplements like Papillex and AHCC. Smoking, excessive alcohol consumption and birth control all contribute to disease progression with HPV.  We have strong evidence to support the link between smoking and alcohol consumption and HPV disease progression. Birth control is another factor that can actually increase a woman's risk of cervical cancer. Studies find that for women with diagnosed HPV, the longer they use oral contraceptives, the higher their risk for cervical cancer. The good news is that once birth control is stopped, the risk does not continue.  Talk to your doctor about what this means for you. If you choose to be on an oral contraceptive, ensure timely screening and monitoring with your trusted health care provider.  You don’t need to “watch and wait”, you can often control HPV with diet and lifestyle  There are many ways to stay ahead of HPV with dietary and lifestyle changes. At Papillex, we strive to find the best available research on diet, supplementation and lifestyle used in the management of HPV.  Some of our favourite science-backed nutrients are folate, vitamin C, selenium, AHCC, carotenoids and more. We also advocate for a healthy lifestyle with lots of movement, stress-reduction, reduced alcohol and smoking consumption, and getting out in nature as much as possible. These practices can help you to better manage your health and stay on top of HPV. The old “watch and wait” approach is out-dated and leaves patients feeling disempowered. It helps to know you have options. There are other cancers caused by HPV Many of us know the risks for cervical cancer, but cancers of the vulva, vagina, penis, anus and oropharynx are also linked to particular strains of HPV. Throat cancer rates are drastically increasing in North America, so it is crucial to be aware of these so that you can get ahead of it. According to the CDC, 90% of both anal and cervical cancers are thought to be a result of HPV. HPV is linked to 70% of vaginal and vulvar cancers and 60% of penile cancers. Up to now, throat cancers were thought to be mostly caused by smoking and alcohol use, but more recent evidence finds that about 60-70% of oropharyngeal cancers may actually be linked to HPV.  Though not all HPV leads to cancer, prevention and early detection are only possible through adequate screening and remaining informed on your risks. Why watch and wait? Head to our instagram and our website for more ideas on how you can take control of your HPV today.
Jun 13, 2022
4 min read
Pap Screening Guidelines for Cervical Cancer

Pap Screening Guidelines for Cervical Cancer

Adrienne Hill-Strathy
The Pap smear is a dreaded appointment for many but, thanks to this handy screening tool, cervical cancer rates and complications from HPV have seen a decline. Increased screening has led to earlier detection of cervical cell changes and with it, led to earlier treatment. Today, Pap smears are incorporated into regular screening for individuals with a cervix. However, when and how often you get tested can differ depending on your country, age, and past HPV status. Read on to learn more about screening in your location. First, what is a Pap smear? The Papanicolaou-stained (Pap) smear was introduced in 1949 by a pathologist named George Papanicolaou. The Pap smear is now the primary screening tool used to assess abnormal cervical changes and screen for the risk of cervical cancers. The Pap smear involves taking a cell sample of the cervix and assessing for any abnormalities. By monitoring cell changes, earlier treatment and interventions can be implemented which can prevent more severe disease. While Pap testing and increased screening have resulted in a decline in cervical complications, there remains some debate over how often early screening should take place. Considering 90 percent of HPV infections will regress over time, screening can also lead to harm such as unnecessary stress on the individual, additional follow-up testing and biopsy, and the potential of unnecessary treatment.  The chances of having an abnormal Pap smear are higher in young individuals and decrease with age. Around 10% of individuals with a cervix aged 20-29 years will have an abnormal test result while only 1.6% of those aged 60-69. Of these abnormal results, 1.5% of 20–29-year-olds will have high-grade lesions that lead to further testing and biopsy. However, more than 50% of these will undergo treatment. Many of these infections would clear on their own and lead to no complication of cervical cancer. For this reason, many countries recommend screening at a later age. Here is what is recommended in Canada, the UK, and the US. Screening Guidelines Differ Depending on Country Canada The Canadian Task Force on Preventive Health Care recommends the following screening for asymptomatic individuals with a cervix without a previously abnormal test and who are sexually active. Screening is not recommended for individuals under 24. The potential harms in this group out weight the benefit of early screening. For individuals with a cervix aged 25-29 screening is weakly recommended every 3 years. The concern for cervical cancer increases in this age group, therefore there are benefits to screening. For those aged 30-69 routine screening every 3 years is strongly recommended. In this age group, the risk of cervical cancer is greater, and screening offers preventative benefits. At the age of 70 regular screening may be ceased. In Canada, the recommendations are used as guidance to be used in discussions with patients. Some women may place a higher value on avoiding cervical cancer and would want to undergo more frequent or earlier screening. While others may prefer to follow the screening guidance. United States The US Preventive Services Task Force sets the screening guidelines in the United States. The US recommendation incorporates high-risk HPV testing, which can help detect high-grade cervical lesions by identifying strains more likely to cause cervical cancers. They recommend the following: Screening begins at age 21-29 and should be followed up every 3 years with cervical cytology. In women aged 30-65, it is recommended to screen every 3 years with cervical cytology and every 5 years with high-risk human papillomavirus testing or every 5 years HPV testing in combination with cytology. The USPSTF recommends against screening in those under the age of 21 and over the age of 65 and those who have had a hysterectomy. United Kingdom The UK has its own set of recommendations through the NHS Cervical Screening Programme. The NHS has also begun including HPV testing in its assessment. Cervical samples will be tested for high-risk Human Papillomavirus to help identify individuals more at risk for developing cervical cancer and implement treatment earlier. Their screening is recommended to begin at age 25 to 65. For those aged 25-49, screening is offered every three years. For those aged 50-64 years of age, it is recommended every five years. What about for those who have had an abnormal Pap previously? Screening guidelines differ if you have previously had an abnormal Pap and HPV has been detected. If your Pap test was abnormal, you were likely referred to a gynecologist for a colposcopy. A colposcopy allows for a better view of the cervix and biopsy. Depending on your level of cell changes and health history, your doctor will recommend a treatment course of action or to watch and wait. In those that have previously tested positive for HPV or had abnormal Paps that turned normal, your doctor will likely recommend follow-up testing a year after a normal result. HPV infections can recur, so it is important to stay on top of testing to see if cell changes recur over time.  The Benefit of Early Detection Deciding when and how often to screen for cervical cancer and HPV, should be discussed with your medical doctor. Early detection has been beneficial in reducing our overall rates of cervical cancer. However, extra screening has also added anxiety and unnecessary procedures to those whose infections would have regressed within 12-36 months. Moreover, detecting infection early also allows for earlier intervention with immune supports like Papillex and lifestyle changes like an anti-inflammatory diet, stress reduction, and exercise.
May 02, 2022
4 min read

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