Being Well Blog

Being informed means being empowered. Welcome to the latest information and actionable insights.

Latest Insights

Is Cervical Cancer Genetic?

Is Cervical Cancer Genetic?

Adrienne Hill-Strathy
Cervical cancer remains the second most common cancer among women worldwide. Certain high-risk strains of the Human Papilloma Virus (HPV) are responsible for causing cervical cancer. Around 70-90% of individuals with HPV will clear the virus 12 to 24 months after infection. However, in few individuals, the viral infection can persist and cause cellular changes to the cervix that may lead to cervical cancer. What allows some people to quickly clear the viral infection and others to develop cancer?  Several identified factors may impact an individual’s ability to clear an infection. These include frequent re-infections, immune health, hormone levels, or infections by more than one HPV type.  Genetic factors also play a role. In this article, we explore the relationship between HPV and genetics. How Do Genes Influence Cancer? Genes play a role in directing healthy cellular development by controlling cell growth and cell death.  Genes that control how our cells grow, work, and stay alive are called oncogenes. Other genes, called tumor suppressor genes, keep cell growth under control and initiate cell death at the right time. Cancer occurs when DNA mutations alter the genes that turn on oncogenes or turn off tumor suppressor genes, allowing abnormal cellular growth. Research has found that high-risk HPV contains special proteins called E6 and E7. These proteins turn off tumor suppressor genes. When these genes are deactivated, cells in the cervix can progress and lead to further gene changes and potentially cancer. Is Cervical Cancer Heritable? Research suggests that a familial predisposition to cervical cancer may be present. If your mother or sister had cervical cancer, your chances of developing cervical dysplasia or cancer are increased. Moreover, the risk increases with the increased degree of genetic relatedness. A Swedish study found that genetic heritability accounted for 27% of the underlying factors for cervical cancer development. The study also tested the role of the environment but found shared environmental factors accounted for only 0-2% of disease progression. The results showed a greater impact than other cancers like colorectal cancer, lung cancer, and melanoma. The reason for these genetic correlations is not completely understood. It could be explained by a few factors: Our genetics may impact our DNA repair pathways associated with CIN3 cervical dysplasia and HPV persistence. Genes have also been associated with supporting viral infection and cell entry. Genotypes may influence an individual’s likelihood of exposure to HPV. For example, genetics may influence an individual’s sexual or risk behaviors, thereby influencing the risk level of contracting HPV. Genetics may also influence an individual’s cervical cancer risk through HLA alleles. Seven alleles have been associated with cervical cancer, while another four showed a negative association.  Specific genotypes like BRACA have also been investigated on cervical cancer. It was found that the BRACA1 genotype was associated with a decreased risk of cervical cancer. The same variant is also associated with an increased risk of inherited breast cancer. Genetics and The Immune System Cervical cancer may also be driven by genetic factors that influence the immune system, decreasing some women’s ability to fight off infections like HPV.  The immune system is the key factor allowing HPV infections to progress from cervical dysplasia to invasive cancer. The progress from infection to cancer takes several years to decades to develop. The innate and adaptive immune responses are responsible for the regression, persistence, and progression of HPV infections. For example, women with HPV infections that evolve into high-grade lesions have a reduced immune cellular response. Genetics may also influence the number of immune cells an individual has to defend against infection. MTHFR Genetic Mutation Some people have a genetic mutation that prevents them from properly converting dietary folate into its active form (5-MTHF) by a process called “methylation”. This mutation may explain why some women with healthy diets and lifestyles struggle to clear the infection. The MTHFR mutation increases the risk of several diseases including heart disease, colon cancer, and breast cancer. Studies evaluating the association between genetic variants of MTHFR and cervical cancer show some association between the MTHFR C677T polymorphism and CIN 3. However, further studies are needed to determine the actual cause. An Emerging Field The research behind genetic predispositions to cervical cancer and cervical dysplasia is very much still evolving. As more research emerges, we may have more clarity as to what leads some to develop more severe reactions to HPV infection than others.
May 17, 2021
3 min read
Normal Pap Smear: Could I Still Have HPV?

Normal Pap Smear: Could I Still Have HPV?

Adrienne Hill-Strathy
The regular Pap test can be a dread for many women. The situation is uncomfortable, and the fear of an abnormal result can be anxiety-provoking. What’s more, the results of a Pap smear can often be confusing. Here, we have provided a breakdown to help you better understand your Pap results and how we can use testing to better prevent complications like cervical cancer. What Is a Pap and HPV Test? The HPV and Pap Smear Tests are the primary ways for women to test for HPV and signs of abnormal cells. A Pap test involves taking a sample of cells from your cervix to assess for any abnormalities. It is usually combined with a pelvic exam and sometimes an HPV test, which screens for the presence of HPV viruses in your cell tissues. What Do Your Pap Results Mean? The test results from a Pap smear can go one of three ways: NORMAL, UNCLEAR, ABNORMAL. Normal: a normal Pap test suggests no abnormal cellular changes on the surface of the cervix. Pap testing will be recommended every three years. Unclear: an unclear test indicates some mild abnormality and usually warrants a repeat Pap test. Mild abnormality could be due to a vaginal or sexually transmitted infection, changes in hormones, such as those seen in pregnancy or menopause, with certain medications, or poor test collection. Abnormal: an abnormal pap test means that cervical cell changes were found. This does not mean that you are positive for cervical cancer but further investigation is needed. Can You Have a Normal Pap Smear But Be Positive for HPV? Because the Pap test and HPV test for two different things, abnormal cellular changes and the presence of HPV in your cells, it is possible for your Pap test to come back normal, but you screen positive for HPV. This results likely means you have HPV, but the virus remains in a state of low activity and has not caused significant abnormal changes to your cervix. HPV is typically cleared by activation of the adaptive immune system, which releases immune molecules called T-cells into the circulation to suppress viral replication. Over time, a healthy immune system should prevent HPV from further proliferating into your cervical epithelial cells and render the virus in a latent state. A normal Pap test could therefore indicate that your immune system is actively suppressing cell proliferation, but the virus is still active. Errors In Pap Testing A normal Pap test could also mean the swab may not have caught the areas of abnormality on your cervix. While Pap testing is a great tool, it isn’t always perfect. Studies find that abnormal findings increase when conventional Pap smears are replaced by liquid-based cytology (LBC). However, because most HPV infections resolve over time and cytology exams lead to costly follow-up investigations with repeat Pap smear and biopsies, HPV reflex testing is being used to identify high-risk strains. HPV Reflex Testing Pap and HPV testing are usually done in combination to evaluate whether the strain of HPV that is infecting a host, has a high risk of developing into cancer. HPV reflex testing can help identify the particular HPV strain that is causing the infection. We know that high-risk HPV types 16, 18, 31, 33, 35, 45, 52, and 58 account for about 88% of all cervical cancers worldwide. Detection of these strains within an individual can help prioritize preventative measures and screening to monitoring changes and cell development. By performing more specific screening we can ensure that individuals at high-risk are getting proper follow ups and avoiding undue stress to minor cases that are unlikely to progress into cervical cancer. It should be noted that HPV reflex screening is not typically included in screening guidelines but is offered as a commercial test to better screen for a patient’s risk. What Can You Do? If you have received a result of a normal Pap test but remain positive for HPV, it is still important for you to take steps to support your immune system and keep watch on the situation. We recommend: Eating a diet rich in plants and high in micronutrients. Supplementing with herbal formulas, like Papillex, and medicinal mushrooms to support your immune system. Developing techniques to reduce daily stressors and manage overwhelm. Limiting the consumption of alcohol and avoiding smoking. Getting daily exercise and movement into your day.
May 03, 2021
3 min read
Epithelial Cell Abnormality: All You Need To Know

Epithelial Cell Abnormality: All You Need To Know

Christine Chung
You go for your normally scheduled pap test, but this time things are different. You get your test results, and you see ABNORMAL. You, along with 8% of Canada’s female population, are wondering the same thing. What does this mean?  In this blog post, we break down what you need to know about the Pap smear, the possible results, and what it means to have epithelial cell abnormality. First, let’s break down what an epithelial cell is. What is an Epithelial Cell? Epithelial cells are found on the surface layers of the body such as the skin, respiratory tract, urinary tract, and organs. The cells create a barrier between the inside and outside of the body, protecting it from invaders like viruses, bacteria, and other pathogens.  Epithelial tissue is one of the four major tissue groups and can be found lining many parts of the digestive system, the epidermis, the oral cavity, many of the body’s glands, and the cervix. There are three types of epithelial cells: squamous, cuboidal, and columnar. Squamous cells are what we commonly examine when it comes to Pap testing and cell abnormality. Squamous cells are found in the esophagus, mouth, and vagina, protecting the body against wear and abrasion. Different layers of Epithelial Cells What Is An Epithelial Cell Abnormality? An Epithelial Cell Abnormality is when an epithelial cell has undergone abnormal cellular changes, which could indicate cancerous or pre-cancerous cells. When abnormal cells are found on the cervix, this is also known as cervical dysplasia. Epithelial cell abnormality and cervical dysplasia are detected through a Pap test. Normal vs Abnormal Cervix Cells Taken from a Pap Smear What is the Pap Test? The Pap test or Pap smear was invented in the 1920s by a gynecologist named George Papanicolaou. While researching, Papanicolaou discovered certain cellular smears taken from the vagina and cervix and viewed under the microscope differed in epithelial cellular normality. His discovery revealed early detection of cancerous cells in women presenting without any current symptoms. The Pap test has now become part of routine physical examination for individuals with female reproductive parts to detect and monitor the presence of precancerous or cancerous cells on the cervix that may progress into cervical cancer.  The test results from a Pap smear can go one of three ways: NORMAL, UNCLEAR, ABNORMAL. Normal: Indicates no cellular changes or precancerous activity was found. Unclear: Often warrants a repeat Pap test. This indicates that your cells could be mildly abnormal, due to a vaginal or sexually transmitted infection, changes in hormones, or poor test collection. Abnormal: An abnormal Pap test means that some level of cervical cell changes were found. It does not mean that you have cervical cancer but further testing is recommended. Pap Smear Tests Are Essential For Detecting HPV Breaking down the Abnormal Pap Test Results The Pap test is a screening test that reports different grades of abnormality. The following table displays the severity of these results from lowest to highest: Degree of Severity Pap Test Result 0 Normal 1 ASC-US 2 LSIL 3 ASC-H 4 HSIL 5 AIS 6 Squamous Carcinoma Abnormal Result Breakdown Here is a breakdown of abnormal Pap test results: Atypical Squamous Cells of Undetermined Significance (ASC-US) The most common of all abnormal Pap test findings. ASC-US means the squamous cells of the cervix look abnormal. This is likely due to an HPV infection. Usually, the cells return to normal on their own, but your doctor will likely recommend monitoring to be safe. Atypical Glandular Cells (AGC) This type of result is unique from the others listed here as they relate to glandular cells instead of squamous cells. Cervical mucus and mucus in the uterus are produced by these glandular cells. An AGC result indicates that there are abnormalities in the cervix’s glandular cells and raises concerns about pre-cancerous or cancerous cells. Further testing and monitoring will be recommended. Low-grade Squamous Intraepithelial Lesions (LSIL) This indicates mild cervical dysplasia, abnormal tissue potentially signifying early stages of cancerous processes. These changes are likely due to an HPV infection. Often these changes return to normal over time but require monitoring. This could also be known as cervical intraepithelial neoplasia, or CIN 1. Atypical Squamous Cells (ASC-H) Atypical squamous cells are another form of cell abnormality that has a high possibility of being HSIL. Further testing must be completed to know for sure. High-grade Squamous Intraepithelial Lesions (HSIL) This result indicates moderate to severe dysplasia. An HPV infection is present and spreading, causing more serious changes. This is still not cancer, but it has a higher risk of progression into cancer if untreated. With adequate support and treatment, it may go back to normal findings. A CIN 2 or 3 classification would fit here. Adenocarcinoma In Situ (AIS) This finding indicates an advanced lesion was found with a high risk to develop into cancer without proper treatment. This is a stage where it is critical to prevent cervical cancer progression. A CIN 3 classification would fit here. Squamous Carcinoma: A positive screening for squamous carcinoma indicates cancer. Squamous cell cervical cancer makes up 80% of all cervical cancers. At this stage, precancerous cells have progressed to cancer and require further treatment of surgery, radiation, chemotherapy, or other immunotherapies. A diagnosis of squamous is quite rare. Women who receive regular Pap tests will catch cervical cell changes before cancer develops and are very unlikely to ever unknowingly reach this stage. Discuss with your healthcare professional how to proceed following abnormal cell results. What does Cervical Intraepithelial Lesion (CIN) mean? The Pap test cannot tell the exact severity of cervical cellular changes. A cervical biopsy taken through colposcopy is needed to find out whether precancer or cancer is actually present. Cervical biopsy results are reported as Cervical Intraepithelial Lesion (CIN) on a grade of 1, 2, or 3.  CIN 1: indicates mild, low-grade changes in the cells. CIN 1 often will go away on its own without treatment. CIN 2: is used for moderate cellular changes. This is a higher-risk for progression into a pre-cancerous stage.  CIN 3: indicates more severe (high-grade) changes, with a higher likelihood to progress to cancer and may be classified as precancer.   A healthy ldiet and ifestyle helps your immune system Frequently Asked Questions: What is an HPV test?In individuals with abnormal Pap test or females above the age of 30, the Pap test may be combined with an HPV test. The HPV test screens for the presence of the HPV virus, which causes cervical cancer. HPV is very common and can be present without any signs of cervical abnormality. It is often tested to determine which strain of HPV you have contracted. Because some strains have a higher chance of progressing to cancer, knowing the specific strain and viral presence can help your doctor monitor your risk. How often do I need to get a Pap test?Pap smears have now been recommended for sexually active females between the ages 25-69 to be performed once every 3 years. If you have had an abnormal Pap your doctor will repeat your Pap every 6- 12 months until they are clear. What should I do following an abnormal Pap?Following an abnormal result, your primary healthcare provider will refer you for colposcopy. A colposcopy allows for closer examination of the cervix using a microscope. A cervical biopsy may also be taken for more accurate detection of cell types. Read more on what you can expect in a colposcopy appointment.  How are abnormal cervical cells treated?Depending on the severity of cervical abnormality your doctor will recommend monitoring or treatment. Treatment usually includes an excisional and ablative treatment where cervical tissue is removed or destroyed. Loop electrosurgical excision procedure (LEEP) and Conization are the two most common excisional treatments. LEEP uses a thin wire loop that carries an electric current to remove abnormal cells. Conization removes a cone-shaped piece of the cervix that contains abnormal cells. Cryotherapy and laser are the two most common ablative treatments.  How can I naturally support my body to clear HPV?A healthy diet and lifestyle are key to supporting your immune system eradicate the virus. Making lifestyle changes such as eating more fruits and vegetables, exercising daily, sleeping at least 7-8 hours a night, cutting out smoking, and excessive alcohol consumption. By making sustainable changes to support your overall health you will also help your immune system clear HPV. We developed the Papillex supplement for this very reason, to boost your immune system and best prepare your body to regress those abnormal cells back to normal cervical cells. Papillex contains high-quality, fine-tuned ingredients hand-picked specifically to fight HPV infections.
May 15, 2020
6 min read
Recover From An Abnormal Pap Smear. Fast.

Recover From An Abnormal Pap Smear. Fast.

Christine Chung
Watch and Wait…or Take Action? How One Doctor Supports Patients to Recover Faster from an Abnormal Pap Smear To celebrate Cervical Cancer Awareness Month, Dr. Amy Kroeker, ND shares her perspective on managing abnormal Paps, and shares a remarkable case of cervical dysplasia that has a happy ending. If you have ever had an abnormal Pap and heard this phrase, you’re not alone. And, if you are anything like me, you don’t like waiting. Cervical dysplasia is caused by the HPV virus which causes normal cervical cells to change form into abnormal cells prone to becoming precancerous or cancerous cells. It is standard medical advice to “watch and wait” when first diagnosed with an abnormal PAP (ie. cervical dysplasia). However, what exactly are we waiting for…and what are we watching? It’s not like we can see our own cervix to check up on it. In my practice, I’ve always found this advice to be excruciating to the female psyche. For 6 months, women are asked to wait, and then the PAP is re-done to see if the cells have converted back to normal cells or continued to progress towards abnormal pre-cancerous or cancerous cells. It is assumed that since the abnormal cells are caused by a virus, that your body may be able to fight the virus off in this amount of time and allow the cells to heal. If they do not, then treatment (often by laser) is required. But wait, if these cells are caused by a virus, isn’t there more we can do to help our bodies fight this virus off? Aren’t there a lot of natural remedies that can help boost our immune systems? Case Study of a 26 year-old female A few years ago, I had a patient with a memorable case of HPV-induced cervical dysplasia. A 26-year-old woman who wanted to boost her own body’s immune system to reverse the abnormal cells. Her gynecologist gave her 6 weeks before doing a laser removal of the cells. At the time, I thought it wouldn’t work. Natural medicine is all about focusing on prevention and I didn’t believe we could reverse abnormal cells in that time frame. I made sure my patient knew there were risks to waiting but since her gynecologist had agreed to wait 6 more weeks, and she was determined to use those 6 weeks to their full advantage, I did some research and came up with a plan to support her own body’s immune system with diet, vitamins, and anti-viral and hormone balancing nutrients. What was the result? A clean PAP. That case, and the research I did for it became my protocol to give women back control during the “watch and wait” phase. I don’t suggest ever delaying treatment once needed and recommended by your doctor or gynecologist but during the “watch and wait” phase I prefer to take action to provide an environment supportive of the best possible outcome. The following are some of the tips I recommend to help boost the immune system while waiting: #1: Diet Emphasize eating vegetables and fruits (at least 7-10 servings per day) to boost antioxidants and increase immune system function. Research shows that high levels of vegetable consumption are associated with a 54% decrease in HPV persistence. Specifically, consume at least one serving per day of a cruciferous vegetable such as broccoli, kale, cauliflower, or Brussel sprouts and at least one serving of dark green leafy vegetables or bright orange/red vegetables at every meal. There are lower rates of HPV infections reported among women with higher intake of carotenes, lutein, zeaxanthin, and vitamin C, and these vitamins and antioxidants are found in brightly colored vegetables and fruits. Lignans, a nutrient found in high concentrations in ground flaxseeds, help to lower levels of free estrogen in circulation. Consuming 2 tbsp per day can help improve the hormone balance necessary for the ovaries, uterus, and cervix to function optimally. As for what foods to avoid; avoid processed foods, foods with added sugar, alcohol, and coffee. These foods create unnecessary stress on the body and hormonal systems and we need to create space in the diet for more nutrient dense foods. #2: Supplements There are a lot of different nutrients with research showing they help the immune system or help the body fight viruses like HPV. These supplements are individualized for each patient so I always recommend working with a licensed naturopathic doctor or functional medicine doctor to tailor a program specific to you. However, I consider the following nutrients since they have the most research. Folic acid – ideally in the active form Vitamin C – higher doses, if possible, from food or supplements Vitamin A – higher doses but if you go above 10,000 IU daily then you need to work with a doctor for liver safety I also like to use a product that contains reishi mushroom, mixed carotenoids, broccoli sprout extract or DIM, and green tea extract – these are all found in the supplement Papillex. I have yet to find a better blend of ingredients combined in one formula for the support of cervical dysplasia. So, next time you are told to “watch and wait” after an abnormal PAP, seek out a licensed naturopathic doctor or functional medicine doctor so you can support your body while it tries to heal and repair from the HPV virus. Why feel helpless while waiting? Take action! Dr. Amy Kroeker, ND practices from her clinic in Winnipeg, Canada. Learn more about Amy at https://www.amykroekernd.com/about
Jan 22, 2020
4 min read
Pap Smear Guidelines 2019

Pap Smear Guidelines 2019

Christine Chung
Why Get A Pap Smear? Routine checkups testing for HPV with your healthcare provider is your saving grace. Prevention is key in cervical cancer. Cervical cancer is a slow-growing cancer that can take years to proliferate to actual cancer. Starting with abnormal cells, CIN I, II, and III, ASC-US, LSIL, HSIL, and eventually, squamous cell carcinoma. It can take your body years to progress through these stages. Regular Pap smears allow for your healthcare provider to track the progression of abnormal cell growth to inform their treatment plan. Most cases of cervical cancer are entirely preventable when caught early. Making simple lifestyle modifications to boost your immune system may be all you need in the early stages. The United States Preventive Services Task Force (USPSTF) recommends screening every 3 years with cervical cytology, using Pap smears, for women aged 21 to 29. Between 30 to 65 years of age, Pap smears once every 3 years are recommended, along with an HPV test alone or combined with a Pap smear every 5 years. What Is A Pap Smear? A Pap smear is a screening procedure involving the collection of a small sample of cells from your cervix. Your cervix is basically a canal from your uterus opening out to the vagina. Your doctor will use a speculum inserted in your vagina and a small brush to collect a sample which is then sent off for testing. Pap smears may be a little uncomfortable, but with proper technique, they should not be painful. Does a Pap Smear Test for STDs? Technically, no. A Pap smear tests for cervical cell changes. This may be due to HPV, or it may be caused by another cancer-causing path. Sometimes your healthcare provider may co-test, which means they would combine a Pap smear with an HPV test, which tests if your cervical cells actually are infected with HPV, specifically high risk HPV (hence the name). If you are concerned about having other STDs, you should discuss your sexual history with your medical doctor before deciding which STD tests to run. What About The HPV Test? The HPV test will detect if your cervical cells are infected with high risk HPV, while the Pap smear will detect any cervical changes, including those that may not be associated with HPV. Who Needs A Pap Smear? Pap Smears are recommended for women between the ages of 21 and 65. Women younger than 21, older than 65, or women who have had a hysterectomy do not need to screen for cervical cancer with prior screening. Because cervical cancer is slow-growing, it is not likely to detect cervical cancer earlier than age 21, even if they are infected earlier. Completing Paps at this age may have more risk than benefit, including fertility implications. If a woman over the age of 65 has never been properly screened for HPV, testing may be indicated. Three consecutive negative cytology tests before 65 is adequate enough to halt screening, even when new partners are reported.
Oct 23, 2019
2 min read
Cervical Cancer and HPV

Cervical Cancer and HPV

Christine Chung
Cervical cancer is the eighth most common cancer in the world and the fourth most frequently diagnosed cancer in women, with over 570,000 new cases in 2018, as stated by the World Health Organization. In this article, we aim to clear up any confusion about HPV, cervical cancer, and how the two are related by answering the following questions: How does it happen? What are the symptoms? How is Human Papillomavirus related to cervical cancer? Could you be at risk? What is Cervical Cancer? Cervical cancer occurs when a cervical cell changes or behaves abnormally, forms cancer cells and then grows into nearby tissue. As with other cancers, the biggest danger can be the spread to other parts of your body. The cervix is part of your reproductive system, and as you may have guessed, is where cervical cancer occurs. It’s the narrow end of your uterus that opens out to your vagina - think of it as a tunnel from your vagina to your uterus. Types of Cervical Cancer The type of cervical cancer is dependent on which cells have become affected: Squamous Cell Carcinoma (70-90% of cervical cancer cases) - the cells affected are the flat, skin-like cells that cover the outer surface of the cervix, known as squamous cells. Adenocarcinoma ( ≈ 10% of cervical cancer cases) - making up the majority of alternative cervical cancer types, adenocarcinoma affects the glandular cells in the passage between the cervix and the womb. Adenosquamous Carcinoma (a minority of cases) - this rare cervical cancer affects both the squamous and glandular cells of the cervix. Small Cell Cancer (very rare aggressive form of cervical cancer) - small cell cancer is the rarest of the four listed here and is more likely to spread quickly to other areas of the body, such as lymph nodes. What Are The Symptoms? Abnormal vaginal bleeding (between periods, after intercourse) Increased vaginal discharge, especially with foul smell Heavy or long periods Painful intercourse Loss of appetite Weight loss Fatigue Do ALL Cervical Cell Changes Cause Cancer? Simply, no. Sometimes cells can change but stop growing or acting abnormally, in which case there can be benign (non-cancerous) growths such as fibroids. These growths can also cause pre-cancerous growths, meaning they are acting abnormally but they are not cancerous yet. These can be detected by routine Pap Smear Tests and is one of the reason why they are so important. What is a Pap Smear? A Pap smear is a screening procedure involving the collection of a small sample of cells from your cervix. Your doctor will use a speculum inserted in your vagina and a small brush to collect a sample which is then sent off for testing. Pap smears may be a little uncomfortable, but with proper technique, they should not be painful. Why Get a Pap? Prevention is key in cervical cancer. Cervical cancer is a slowly developing form of the disease that can take years to become fully-fledged cancer. For the most common form of cervical cancer - squamous cell carcinoma - the individual starts developing abnormal cells that then become more and more affected. The levels of cell abnormality are graded by the terms CIN I, II, and III, ASC-US, LSIL and HSIL, before being classified as cancer. These terms may be confusing, but can simply be thought of as technical medical terms which help you and medical professionals understand at what stage of abnormality your cells have become. It can take your body years to progress through these stages. Regular pap smears allow for your healthcare provider to track the progression of abnormal cell growth to inform the optimal treatment plan.   How is HPV Related? Human Papillomavirus is one of the most common viruses that affect the world population, being the most sexually transmitted infection in the United States. HPV affects millions of men and women every year. The Center for Disease Control and Prevention estimates that almost every sexually active adult will get HPV at some point in their lifetime. It can be spread by skin to skin contact, most commonly through sexual activity. In most cases, HPV is found to be the cause of cervical cells acting abnormally. How does it become Cervical Cancer? Not all HPV infections will cause cancer. In fact, only a few out of the known 100+ strains of HPV can lead to cancer. Most of the time, with a robust immune system, your body is able to clear these infections without any symptoms! When we have a weakened immune system however, or when our bodies are invaded by a strong strain of HPV, cell proliferation - the rapid increase in abnormal cervical cells - can occur. This can lead to cervical intraepithelial neoplasia (CIN), one of the grading systems mentioned before in this article, which over a number of years can lead to more abnormal cells and eventually cancer.
Sep 30, 2019
4 min read
About HPV Testing

About HPV Testing

Dr Elizabeth Goldspink
Cervical cancer is the fourth most frequently diagnosed cancer in women, as stated by the World Health Organization to account for 6.6% of cancers in women.  Cervical cancer has a very good prognosis if it is caught early. The best treatment in the case of cervical cancer is prevention. Prevention, routine screening, early diagnosis, and appropriate treatment makes cervical cancer very manageable.  Being proactive with your health, in all aspects, is essential for optimal prevention. Keep on reading below to know everything about HPV testing, and how you can be proactive with your health.  What is HPV? Human Papilloma Virus, or HPV, is a common virus that affects humans, being claimed by the Centers for Disease Control and Prevention as the most sexually transmitted infection in the United States. It affects millions of men and women every year. In fact, it is so common that the CDC estimates that HPV will be contracted by almost every sexually active adult in their lifetime. Transmission HPV can be spread by skin to skin contact, most commonly through sexual activity. Although some people may not be aware of this, but it includes oral and anal sex.  How Does It Become Cervical Cancer? Although not all HPV infections will cause cervical cancer, the rates of cervical cancer increase every year. Among the hundreds of HPV strains that have been identified, only a handful are likely to cause cervical cancer.  Like any other virus, your body should be able to fight off HPV when you come into contact with it. However, when your immune system is down for the count, that’s when HPV can proliferate and cause growth of abnormal cervical cells, cervical dysplasia, and eventually, growth of cancerous cells.  Pap Smears and HPV Tests The Pap Smear is the recommended test that should be routinely performed by a trusted medical professional to screen for the potential of cervical cancer progression. What is a Pap Smear? A Pap smear collects a small sample of cervical cells using a small brush. Your doctor will insert a speculum into your vagina in order to get an accurate sample from your cervix. This step may be a little uncomfortable, but should be relatively painless.  How Often Should I Get a Pap? The United States Preventative Services Task Force (USPSTF) recommends sexually active women between the ages of 21 to 65 to receive routine Pap smears every 3 years. Women between the ages of 30 and 65 can choose to prolong their screening exams to every 5 years, paired with an HPV test. What is an HPV Test? The HPV test is different from routine Pap screenings. Pap smears test your cervical cells to see if they are cancerous or potentially on their way to being cancerous. The HPV test cannot tell you the status of your cervical cells. It will test for the presence of HPV in your body, typically high risk HPV.  Testing for high risk HPV will test for specific strains of HPV, like HPV 16 and HPV 18 that are associated with high risk for cervical cancer progression.  The HPV test is usually recommended if your Pap repeatedly shows abnormal results, or if you are over the age of 30 and wish to spread out your routine Paps.  The result of the HPV test will usually help your doctor decide when to begin treatments that may be more invasive.  Natural, Proactive Steps  If you have abnormal cell growth detected on your Pap smear, your medical doctor is very unlikely to begin treatment. Most HPV infections are easily cleared by a strong, healthy immune system. Your immune system can be supported in a number of natural ways: Eat plenty of fruits and vegetables Quit smoking Reduce alcohol consumption Drink green tea Exercise to sweat
Aug 28, 2019
3 min read

Example subheading

Subscribe & Save

  • Savings of up to 20% off
  • Plus Enjoy Free Shipping to US / CA
  • Switch or Pause anytime
  • Peace of Mind