Being Well Blog

Being informed means being empowered. Welcome to the latest information and actionable insights.

Latest Insights

HPV Immune System: Why Immunity Matters More Than You Think After a Diagnosis

HPV Immune System: Why Immunity Matters More Than You Think After a Diagnosis

Lovisa Alatalo
It’s not just about avoiding colds. Your immune system plays a lead role in helping your body clear HPV, and if it’s weighed down by inflammation, it might not be performing at its best. How Does Your Immune System Help Fight HPV? HPV is a common viral infection, and your immune system is your first line of defense. When HPV enters the picture, it’s your immune system - specifically your T-cells - that recognizes and targets infected cells. These vigilant defenders work quietly behind the scenes, mounting a response that can fight the virus. But here’s the catch: chronic inflammation - often hidden in plain sight - can dull this immune response. It lulls your T-cells into low gear and keeps your body in a reactive, defensive state, which leaves less bandwidth to focus on fighting HPV. Most people with HPV don’t notice anything unusual. They may not feel “sick” or run down, but at a cellular level, persistent HPV infections can keep the body in constant defense mode. That means your immune system is working overtime on background fires instead of directing its full strength toward combating HPV. T-Cells, NK Cells, and the HPV Immune Response Your immune system is made up of many moving parts, but two types of cells are particularly important for HPV: T-cells are adaptive immune cells that recognize and destroy HPV-infected cells. Chronic inflammation, often fueled by lifestyle risk factors like poor diet, smoking, unmanaged stress, and environmental toxins, can impair T-cell activation and reduce immune activity. Natural Killer (NK) cells are part of your innate immunity. They act quickly, scanning your body for cells that don’t look right - including virus-infected cells. Research shows that boosting NK cell activity is linked to faster combatting of HPV and better long-term outcomes When inflammation becomes chronic, it “distracts” both T-cells and NK cells. Instead of focusing on viral defense, the immune system is caught in a cycle of constant background repair. The result? A slower, less effective response to HPV. What Can You Do to Support Immunity Naturally? The good news: your immune system is highly adaptable. Even small, consistent changes can help bring inflammation down and restore balance. Eat anti-inflammatory foods: Prioritize colorful fruits and vegetables, leafy greens, cruciferous veggies (like broccoli and kale), and whole plant foods rich in antioxidants. Manage stress: Practices like mindfulness, yoga, or even a daily walk can lower stress hormones that otherwise keep the immune system in overdrive. Prioritize quality sleep: Sleep isn’t just rest - it’s when your immune system resets. Aim for 7-9 hours of restful sleep each night. Move your body: Regular, moderate movement improves circulation, supports immune balance, and helps reduce inflammation. You don’t need intense workouts - consistency matters more. Break Bad Habits – Beyond dietary considerations, not smoking, abstaining from recreational drugs and alcohol, and avoiding egregious amounts of stress will help alleviate excess load on your immune system. Smokers exhibit a 200-300% higher incidence of cervical dysplasia. Drink Green Tea – There is a growing body of evidence that suggests the flavonoid ECGC found in green tea may inhibit the development of HPV warts and cervical lesions. Supporting your immune system doesn’t just help manage HPV - it can also play a role in helping the body prevent HPV from progressing into long-term issues. Can Supplements Like Papillex® and AHCC® Help? For patients with HPV,  reducing smoking and stress can significantly support immune health. Lifestyle changes create the foundation for immune strength. But sometimes your body needs additional, targeted support. That’s where supplements like Papillex® and AHCC® come in. What is Papillex®?Papillex® is a doctor-formulated, plant-based supplement designed specifically to support people managing HPV. It combines a unique blend of nutrients and plant compounds that: Promote cervical cellular health (broccoli sprout extract with indole-3-carbinol, DIM, and sulforaphane) Support immune resilience (reishi mushroom, astragalus, zinc, selenium, folate, vitamins C & E) Provide antioxidant protection (green tea extract, carotenoids, lycopene) Papillex® helps replenish key nutrients that research shows may be low in patients with HPV, creating a supportive environment for your immune system to do its work. What is AHCC® (Active Hexose Correlated Compound)?AHCC® is a clinically studied supplement derived from shiitake mushrooms. It works differently than Papillex® - instead of replenishing nutrients, it modulates immune cell activity: Enhances NK cell activity Improves T-cell cytokine production Supports immune memory and long-term defense Clinical research has shown AHCC® may help support HPV clearance when taken consistently. It’s widely used in immune health, from viral support to recovery and resilience. Why Use Them Together?Papillex® and AHCC® complement each other beautifully: one helps refill the immune system’s toolbox, while the other sharpens the tools themselves. Together, they create a more comprehensive immune-support approach. What’s a Simple Roadmap for Supporting Immunity After HPV? If you’ve recently been diagnosed with HPV, supporting your immunity can feel overwhelming. Breaking it down into steps can help. Weeks 1–4 Focus on anti-inflammatory basics: whole foods, stress management, better sleep. Begin small habits like adding a serving of cruciferous veggies daily. Weeks 3–6 Add Papillex® consistently. Notice subtle changes like energy, digestion, or overall vitality. Weeks 5–8(Optional, consult your healthcare provider) Consider adding AHCC® for enhanced immune support. Weeks 9–12 Reassess: Are you feeling more resilient? Have lifestyle changes become second nature? Continue with Papillex® for maintenance and AHCC® as recommended. Small steps add up. Over three months, you’ll have layered lifestyle changes with targeted support - giving your immune system the best environment to respond to HPV. The Bottom Line? An HPV diagnosis can feel out of your hands - but your immunity doesn’t have to. Your body’s resilience lies in how you support it. The immune system isn’t just for colds and flu - it’s your frontline in combating HPV. By lowering inflammation, nurturing your lifestyle, and choosing evidence-backed support like Papillex® and AHCC® supplements, you’re giving your body the best chance to thrive. References Smith J, et al. Active Hexose Correlated Compound (AHCC) and persistent HPV infections: Clinical outcomes. Frontiers in Oncology. 2019. Read here Ostrander EA, et al. AHCC® supplementation improves immune function in women with HPV. J Gynecologic Oncology. 2022. Read here Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Letters. 2008. Read here Rezoagli E, et al. Reishi mushroom (Ganoderma lucidum) and immune regulation: From traditional use to clinical applications. Nutrients. 2020. Read here zur Hausen H. Papillomaviruses and cancer: From basic studies to clinical application. Nature Reviews Cancer. 2002. Read here CDC. Human Papillomavirus (HPV) and Cancer. Centers for Disease Control and Prevention. Read here
Aug 25, 2025
5 min read
Does a Pap Smear Hurt?

Does a Pap Smear Hurt?

Lovisa Alatalo
We understand that the thought of a Pap smear can be intimidating for many women. Many individuals feel anxious about the potential discomfort or pain associated with the process. If you're wondering, "Does a Pap smear hurt?" you're not alone. In this comprehensive guide, we'll address your concerns, explain what to expect during the exam, and provide tips to make the experience as comfortable as possible! Understanding the Pap Smear A Pap smear, also known as a Pap test, is a routine screening to check the health of the cervix. The test involves gathering cells from the cervix, the lower part of the uterus that opens into the vagina. These cells are then examined under a microscope to detect any abnormalities that could indicate potential health concerns. The Purpose of a Pap Smear The primary goal of a Pap test is to detect any changes in cervical cells that might indicate potential problems. Catching abnormal cells in their initial stages allows for preventive measures and treatments that can help maintain cervical health. Does a Pap Smear Hurt? The experience of a Pap smear can vary from person to person. While some women report mild discomfort, others may find the exam more uncomfortable. However, it's important to note that a Pap smear should not be painful. Factors Influencing Discomfort Several factors can influence the level of discomfort experienced during a Pap smear: Anxiety and Tension: Feeling anxious or tense can make the muscles in the pelvic area tighten, increasing discomfort. Positioning: The position in which you lie in during the exam can affect comfort. Your healthcare provider will guide you into a position that allows for easy access to the cervix while keeping you as comfortable as possible. Speculum Size: The speculum, a medical instrument used to hold the vaginal walls open, comes in different sizes. Your healthcare professional will choose the appropriate size for you. Technique of the Examiner: The skill and experience of the professional performing the Pap smear can also influence comfort. A gentle and experienced examiner can make the process more tolerable. What to Expect During a Pap Smear Understanding what happens during a Pap smear can help alleviate some of the anxiety and make the experience smoother. Preparing for the Exam Before the exam begins, your healthcare professional will explain the process and answer any questions you may have. You will be asked to undress from the waist down and lie on an examination table with your feet placed in stirrups. Insertion of the Speculum The healthcare professional will gently insert a speculum into your vagina. The speculum holds the vaginal walls open, allowing the examiner to see the cervix. This part of the exam may cause a sensation of pressure or mild discomfort but should not be painful. Collection of Cervical Cells Once the speculum is in place, the examiner will use a small brush or spatula to gather cells from the cervix. This may feel like a light scraping or brushing. The cell collection process is usually quick and should not cause significant pain. Removal of the Speculum After the cells are collected, the examiner will carefully remove the speculum. The entire exam typically takes just a few minutes. Who Performs a Pap Smear? You might be wondering who exactly performs this important test. Rest assured, there are several types of healthcare professionals who are well-trained and experienced in conducting Pap smears. Here’s a closer look at who you might encounter during your appointment: Gynecologists: Gynecologists are specialists in women’s reproductive health. They frequently perform Pap smears as part of routine gynecological exams. If you’re seeing a gynecologist, you can feel confident knowing they have extensive experience with this procedure. Primary Care Physicians: Your primary care doctor, who you see for general health check-ups, might also perform Pap smears. They are trained to handle a wide range of health issues, including routine screenings like the Pap smear. Nurse Practitioners: Nurse practitioners (NPs) are advanced practice nurses with specialized training. They can perform many of the same tasks as doctors, including Pap smears. NPs are known for their patient-centered approach, often taking extra time to ensure you’re comfortable and informed throughout the process. Physician Assistants: Physician assistants (PAs) work closely with doctors and are also trained to perform Pap smears. They are skilled in many medical procedures and can provide comprehensive care under the supervision of a physician. Obstetricians: If you’re pregnant or planning to be, you might see an obstetrician, a doctor who specializes in pregnancy and childbirth. Obstetricians often perform Pap smears during routine prenatal visits to ensure your reproductive health is monitored. No matter who performs your Pap smear, these professionals are dedicated to making the experience as comfortable as possible. They understand that the procedure can be intimidating and will take steps to ensure you feel at ease. Tips for a More Comfortable Pap Smear Here are some tips to help make your Pap smear experience as comfortable as possible: Communicate with Your Healthcare Provider:  Let your healthcare professional know if you are feeling anxious or have concerns about discomfort. They can take steps to make the exam more comfortable for you. Practice Relaxation Techniques: Deep breathing, visualization, and other relaxation techniques can help reduce anxiety and tension during the exam. Try to focus on your breathing and maintain a calm mindset. Schedule Wisely: If possible, schedule your Pap smear when you are not menstruating, as this can make the exam more comfortable. Although it is not ideal, this does not automatically mean you need to reschedule. Click here to learn more. Use the Bathroom Beforehand: Emptying your bladder before the exam can help reduce discomfort caused by pressure. Consider Pain Relief: If you are particularly anxious or sensitive, you may ask your healthcare professional about taking an over-the-counter pain reliever before the procedure. Managing Anxiety and Tension Feeling anxious about a Pap smear is completely normal. Here are a few techniques to help manage your anxiety and make the experience more comfortable: Mindfulness and Meditation:  Practicing mindfulness or meditation before your appointment can help calm your mind and reduce anxiety. Listening to Music: Some clinics allow you to listen to music during the exam. Bringing your favorite calming playlist can help distract you and keep you relaxed. Bringing a Friend:  If allowed, consider bringing a friend or family member for support. Having someone you trust can help you feel more at ease. Addressing Common Concerns Bleeding After a Pap Smear Light bleeding or spotting is common after a Pap smear and is usually not a cause for concern. Here's what you should know: Why It Happens: The process of collecting cervical cells can sometimes cause minor irritation to the cervix, leading to light bleeding or spotting. Duration: This bleeding typically lasts for a day or two and should be very light. When to Worry: If you experience heavy bleeding or prolonged spotting, contact your healthcare professional for further evaluation. Pain During the Exam "What if I feel pain during the Pap smear?"  If you experience pain during the Pap smear, let your healthcare professional know immediately. They can adjust the exam to make it more comfortable for you. Remember, the goal is to ensure your comfort and health. Embarrassment and Self-Consciousness "I'm embarrassed about the exam." It's natural to feel embarrassed or self-conscious about a Pap smear. Remember that healthcare professionals perform these procedures regularly and are focused on your health and comfort. They are trained professionals who have seen it all and are there to help you. Understanding Abnormal Results "What if my results are abnormal?"  Receiving abnormal results can be concerning, but it's important to remember that abnormal Pap smear results do not necessarily mean you have a serious condition. Many factors can cause abnormal results, such as infections or inflammation. Your doctor will guide you through the next steps, which may include additional testing or treatment. Importance of Regular Pap Smears Regular Pap smears are crucial for maintaining cervical health. The American College of Obstetricians and Gynecologists recommends that individuals with a cervix begin Pap smears at age 21 and continue with regular screenings as advised by their healthcare professional. Knowing when to start getting Pap smears and how often to have them is crucial for maintaining your cervical health. Here are the current recommendations based on age and health history: Ages 21-29 For individuals between the ages of 21 and 29, it is recommended to have a Pap smear every three years. Starting at age 21, regardless of sexual activity, is important because it allows for early detection of any potential abnormalities in the cervical cells. Ages 30-65 For those aged 30 to 65, the recommendations can vary based on individual health needs and the type of testing. There are two common options: Pap Smear Every Three Years: Continue with the Pap smear alone every three years if your previous results have been normal. Pap Smear Plus HPV Testing Every Five Years: Another option is to have a Pap smear combined with HPV (human papillomavirus) testing every five years. This co-testing is effective because HPV is a significant risk factor for cervical health issues. Over 65 For individuals over 65, the necessity of continuing Pap smears depends on your health history: Regular Screening History: If you have had regular screenings with normal results over the past ten years, you may be able to stop having Pap smears. However, it’s important to consult with your healthcare professional to make this decision. History of Abnormal Results: If you’ve had a history of abnormal Pap smear results or other cervical health issues, your healthcare professional may recommend continuing with regular screenings. Special Circumstances Certain health conditions and risk factors might alter the frequency of your Pap smears. For instance: Weakened Immune System: Individuals with a weakened immune system, such as those with HIV, may need more frequent screenings. History of Cervical Health Issues: If you have a history of cervical dysplasia or cervical issues, more frequent monitoring may be necessary. Exposure to DES: Those who were exposed to diethylstilbestrol (DES) before birth may require more regular screenings. Preventive Measures In addition to regular Pap smears, you can take other steps to reduce your risk of cervical issues, including: Getting the HPV Vaccine: The HPV vaccine can help protect against the types of HPV that most commonly cause cervical issues. Talk to a doctor about if this option might be right for you. Practicing Safe Sex: Using condoms and having regular STI tests can help reduce your risk of HPV and other sexually transmitted infections. Avoiding Smoking: Smoking can increase your risk of cervical issues, so avoiding tobacco products is beneficial for your overall health. Things to Remember While a Pap test may cause mild discomfort for some, it should not be painful. Understanding the process and following the tips provided can help make the experience as comfortable as possible. Regular Pap smears are an essential part of maintaining your cervical health and detecting any abnormalities early, ensuring the best possible outcomes. Don't forget, your healthcare professional is there to support you and address any concerns you may have. Don't hesitate to communicate openly with them to ensure a positive and comfortable test. By addressing your concerns and providing detailed information about the Pap smear, we hope to alleviate any anxiety you may have and encourage you to prioritize your cervical health through regular screenings.
Jun 18, 2024
10 min read
Abnormal Pap? Here's What To Do Next

Abnormal Pap? Here's What To Do Next

Victoria Gasparini
In 2022, an estimated 14,100 women in the United States have been/will be diagnosed with cervical cancer, caused by HPV. In 2020, over 600,000 women were diagnosed across the globe. While the HPV vaccine has drastically reduced cervical cancer rates as a direct result of preventing high-risk HPV, there are still approximately 4300 deaths per year in the United States alone, from cervical cancer. Take comfort knowing that most HPV cases do not cause cancer, and that many strains of HPV can be controlled and suppressed naturally by supporting the body’s immune system and encouraging adequate viral clearance. The high risk strains of HPV are 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 66 and 68. HPV 16 and 18 are typically the higher risk types and are responsible for most types of HPV-related cancers.  What to do after receiving an abnormal pap smear The Pap smear involves taking a cell sample of the cervix and assessing for any abnormalities. By monitoring cell changes, earlier treatment and interventions can be implemented which can prevent more severe disease. If you receive an abnormal pap smear result, it is best to talk to your doctor about what your next steps are. This may include more frequent tests, among other possible solutions. Unfortunately, from a conventional standpoint, the advice is typically to “watch and wait” at this point in the diagnosis.  Fortunately, more and more research is finding that there are ways to control and manage HPV naturally, with dietary and lifestyle changes. Let’s dive into your post-diagnosis plan, below.  First things first, know that you aren’t alone.  HPV is one of the most common sexually transmitted infections, affecting 80% of sexually active women. In fact, most sexually active men and women will contract some strain of HPV at some point in their lives. It is not uncommon to have an abnormal pap smear during routine testing. It is, however, important to do what you can to get HPV under control.  Talk to your doctor about follow-ups, strains and risk. While Pap testing and increased screening have resulted in a decline in cervical complications, there remains some debate over how often early screening should take place. Considering 90 percent of HPV infections will regress over time, screening can also lead to harm such as unnecessary stress on the individual, additional follow-up testing and biopsy, and the potential of unnecessary treatment.  The chances of having an abnormal Pap smear are higher in young individuals and decrease with age. Around 10% of individuals with a cervix aged 20-29 years will have an abnormal test result while only 1.6% of those aged 60-69. Of these abnormal results, 1.5% of 20–29-year-olds will have high-grade lesions that lead to further testing and biopsy. However, more than 50% of these will undergo treatment. Many of these infections would clear on their own and lead to no complication of cervical cancer. Depending on where you live and your unique, individual case - your screening guidelines may differ. It is best to work with your physician to develop a plan that is right for you. Find out the screening guidelines in your country here.  Adopt a healthy immunity plan.  We dive into the research on building your immune system to help prevent and clear infections like HPV. Here are some of our favorite, evidence-based tips for building and adopting a healthy immunity plan to help you take control of HPV. Find movement that you enjoy  Consistency is key when it comes to exercise and movement - so if it does not come naturally, know that you probably won’t stick with it. Try finding a daily movement you enjoy such as walking outdoors, weight lifting, kayaking, swimming, hiking, rock climbing - anything that gets you up and going.  Eat a wide array of colorful vegetables and fruits. The more variety you consume with regards to veggies and fruits, the better. Nutrients like carotenoids, sulforaphane, folate, vitamin C, selenium and more, have all been shown to boost immunity and increase clearance of HPV.  While all foods are welcome in a healthy, balanced diet, it is best to focus on anti-inflammatory, antioxidant and phytonutrient-rich foods, with limited intake of starches and sugars. You can find out more about diet and HPV here.  Practice mindfulness  Addressing stressors in our lives is often the biggest barrier to healing, and also often the most important barrier to knock down. The connection between stress and persistent infections is clear which is what makes mindfulness such an integral part of your healing. Studies continuously find a connection between stress and its impact on immunity, which is supported in pathogenesis and persistence of HPV infections. You cannot always control stressful events from occurring, but you can manage perceived stress through methods of talk therapy, finding good friends to chat with, getting adequate sleep and nutrients, and getting outside in nature. Reducing perceived stressors can help with HPV disease management and progression and is an important part of any HPV treatment plan. Other things you can do to manage stress include, positive self-talk and reinforcement, surrounding yourself with positive people, trying acupuncture and/or massage, and more. Click here for more stress-management tips.  Most of all... It's crucial to remember that abnormal pap smears are extremely common, and in many cases, they resolve on their own. Be gentle with yourself during this process. While a "watch and wait" approach is typical, being proactive about your health is essential. There are options available, empowering you to take charge of your healthcare journey. By staying informed and proactive, you can navigate this experience with confidence and assurance, ultimately ensuring your health and peace of mind.
Oct 02, 2023
4 min read
The Role of Nutrition in Cervical Dysplasia

The Role of Nutrition in Cervical Dysplasia

Victoria Gasparini
Cervical dysplasia, characterized by abnormal changes in the cells of the cervix, is a condition that can potentially progress to cervical cancer if left untreated. Medical interventions such as colposcopy and even the "watch and wait" method, are common when diagnosed with dysplasia of the cervix, but there's an additional step we can take to help manage this, reducing our long term risk for cervical cancer and enhancing our health and well-being on all levels. At Papillex®, we have consistently emphasized the notion that merely "watching and waiting" for our health to deteriorate before taking action is insufficient. Our conviction is well-supported by compelling data. The abundance of evidence linking nutrition to cervical health and dysplasia suggests that it could very well be the intervention you've been looking for. Nutrition principles to follow Emphasize the use of antioxidant-rich foods Antioxidants are powerful compounds that help protect our cells from damage caused by free radicals. Studies suggest that oxidative stress may play a role in the development and progression of cervical dysplasia. Including antioxidant rich foods in your diet can help combat oxidative stress and support cervical health. Colorful fruits and veggies, like berries, citrus fruits, dark leafy greens, bright bell peppers, eggplant and tomatoes are all excellent sources of antioxidants. Increase intake of folate and other B vitamins Folate, along with other B vitamins like B6 and B12, are crucial for DNA synthesis and repair. Research suggests that low levels of folate may be associated with an increased risk of cervical dysplasia. Incorporating folate-rich foods such as leafy greens, legumes, citrus fruits, and fortified grains can help ensure adequate intake. Additionally, a balanced diet that includes lean meats and fish, with moderate amounts of dairy (if tolerated) can help provide these essential nutrients, as well. Up your Vitamin C Vitamin C is another crucial nutrient for immune function and collagen synthesis. Studies have shown that higher vitamin C levels are associated with a lower risk of cervical dysplasia and progression to cervical cancer. Citrus fruits, strawberries, kiwi, bell peppers, and broccoli are all excellent sources of vitamin C that can all be easily incorporated into your daily meals. Get those healthy fats in Incorporating healthy fats into your diet is essential in hormone regulation and overall health. Opt for sources such as avocados, nuts, seeds, fatty fish and olive oil. These fats provide important nutrients and contribute to a well-rounded and nourishing diet. Reduce your intake of saturated and trans fats as these tend to be more inflammatory. If you're thirsty, you're already dehydrated! Proper hydration is vital for overall health, including cervical health. Drinking an adequate amount of water helps maintain optimal cell function and supports the body's natural detoxification processes. Non-sugary electrolyte beverages can also help you achieve a more robust amount of minerals. Aim for at least eight glasses of water per day and reduce consumption of sugary beverages.
Aug 07, 2023
2 min read
So, You've Had an Abnormal Pap, Now What?

So, You've Had an Abnormal Pap, Now What?

Victoria Gasparini
In 2022, an estimated 14,100 women in the United States have been or will be diagnosed with cervical cancer, caused by HPV. In 2020, over 600,000 women were diagnosed across the globe. While the HPV vaccine has drastically reduced cervical cancer rates as a direct result of preventing high-risk HPV, there are still approximately 4300 deaths per year in the United States alone, from cervical cancer. Take comfort knowing that most HPV cases do not cause cancer, and that many strains of HPV can be controlled and suppressed naturally by supporting the body’s immune system and encouraging adequate viral clearance. The high risk strains of HPV are 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 66 and 68. HPV 16 and 18 are typically the higher risk types and are responsible for most types of HPV-related cancers.  What to do after receiving an abnormal pap smear The Pap smear involves taking a cell sample of the cervix and assessing for any abnormalities. By monitoring cell changes, earlier treatment and interventions can be implemented which can prevent more severe disease. If you receive an abnormal pap smear result, it is best to talk to your doctor about what your next steps are. This may include more frequent screenings, among other possible solutions. Unfortunately, from a conventional standpoint, the advice is typically to “watch and wait” at this point in the diagnosis.  Fortunately, more and more research is finding that there are ways to control and manage HPV naturally, with dietary and lifestyle changes. Let’s dive into your post-diagnosis plan, below.  First things first, know that you aren’t alone.  HPV is one of the most common sexually transmitted infections, affecting 80% of sexually active women. In fact, most sexually active men and women will contract some strain of HPV at some point in their lives. It is not uncommon to have an abnormal pap smear during routine testing. It is, however, important to do what you can to get HPV under control.  Talk to your doctor about follow-ups, strains and risk. While Pap testing and increased screening have resulted in a decline in cervical complications, there remains some debate over how often early screening should take place. Considering 90 percent of HPV infections will regress over time, screening can also lead to harm such as unnecessary stress on the individual, additional follow-up testing and biopsy, and the potential of unnecessary treatment.  The chances of having an abnormal Pap smear are higher in young individuals and decrease with age. Around 10% of individuals with a cervix aged 20-29 years will have an abnormal test result while only 1.6% of those aged 60-69. Of these abnormal results, 1.5% of 20–29-year-olds will have high-grade lesions that lead to further testing and biopsy. However, more than 50% of these will undergo treatment. Many of these infections would clear on their own and lead to no complication of cervical cancer. Depending on where you live and your unique, individual case - your screening guidelines may differ. It is best to work with your physician to develop a plan that is right for you. Find out the screening guidelines in your country here.  Adopt a healthy immunity plan.  At Papillex, we dive into the research on building your immune system to help prevent and clear infections like HPV. Here are some of our favorite, evidence-based tips for building and adopting a healthy immunity plan to help you take control of HPV.  Find movement that you enjoy  Consistency is key when it comes to exercise and movement - so if it does not come naturally, know that you probably won’t stick with it. Try finding a daily movement you enjoy such as walking outdoors, weight lifting, kayaking, swimming, hiking, rock climbing - anything that gets you up and going.  Eat a wide array of colorful vegetables and fruits. The more variety you consume with regards to veggies and fruits, the better. Nutrients like carotenoids, sulforaphane, folate, vitamin C, selenium and more, have all been shown to boost immunity and increase clearance of HPV.  While all foods are welcome in a healthy, balanced diet, it is best to focus on anti-inflammatory, antioxidant and phytonutrient-rich foods, with limited intake of starches and sugars. You can find out more about diet and HPV here.  Practice mindfulness  Addressing stressors in our lives is often the biggest barrier to healing, and also often the most important barrier to knock down. The connection between stress and persistent infections is clear which is what makes mindfulness such an integral part of your healing. Studies continuously find a connection between stress and its impact on immunity, which is supported in pathogenesis and persistence of HPV infections. You cannot always control stressful events from occurring, but you can manage perceived stress through methods of talk therapy, finding good friends to chat with, getting adequate sleep and nutrients, and getting outside in nature. Reducing perceived stressors can help with HPV disease management and progression and is an important part of any HPV treatment plan. Other things you can do to manage stress include, positive self-talk and reinforcement, surrounding yourself with positive people, trying acupuncture and/or massage, and more. Click here for more stress-management tips.  The most important thing you can do for yourself after receiving an abnormal pap smear, is to be gentle with yourself. HPV is not your fault. It is a virus that can be managed and controlled. Holding onto shame can prevent us from living a healthy life, and can contribute to stress and unhealthy behaviors that impair our immune system. Letting go of the shame associated with HPV may be foundational to our healing. Be kind to yourself. For more tips on managing HPV, follow us on instagram @papillex.
Aug 22, 2022
4 min read
Pap Screening Guidelines for Cervical Cancer

Pap Screening Guidelines for Cervical Cancer

Adrienne Hill-Strathy
The Pap smear is a dreaded appointment for many but, thanks to this handy screening tool, cervical cancer rates and complications from HPV have seen a decline. Increased screening has led to earlier detection of cervical cell changes and with it, led to earlier treatment. Today, Pap smears are incorporated into regular screening for individuals with a cervix. However, when and how often you get tested can differ depending on your country, age, and past HPV status. Read on to learn more about screening in your location. First, what is a Pap smear? The Papanicolaou-stained (Pap) smear was introduced in 1949 by a pathologist named George Papanicolaou. The Pap smear is now the primary screening tool used to assess abnormal cervical changes and screen for the risk of cervical cancers. The Pap smear involves taking a cell sample of the cervix and assessing for any abnormalities. By monitoring cell changes, earlier treatment and interventions can be implemented which can prevent more severe disease. While Pap testing and increased screening have resulted in a decline in cervical complications, there remains some debate over how often early screening should take place. Considering 90 percent of HPV infections will regress over time, screening can also lead to harm such as unnecessary stress on the individual, additional follow-up testing and biopsy, and the potential of unnecessary treatment.  The chances of having an abnormal Pap smear are higher in young individuals and decrease with age. Around 10% of individuals with a cervix aged 20-29 years will have an abnormal test result while only 1.6% of those aged 60-69. Of these abnormal results, 1.5% of 20–29-year-olds will have high-grade lesions that lead to further testing and biopsy. However, more than 50% of these will undergo treatment. Many of these infections would clear on their own and lead to no complication of cervical cancer. For this reason, many countries recommend screening at a later age. Here is what is recommended in Canada, the UK, and the US. Screening Guidelines Differ Depending on Country Canada The Canadian Task Force on Preventive Health Care recommends the following screening for asymptomatic individuals with a cervix without a previously abnormal test and who are sexually active. Screening is not recommended for individuals under 24. The potential harms in this group out weight the benefit of early screening. For individuals with a cervix aged 25-29 screening is weakly recommended every 3 years. The concern for cervical cancer increases in this age group, therefore there are benefits to screening. For those aged 30-69 routine screening every 3 years is strongly recommended. In this age group, the risk of cervical cancer is greater, and screening offers preventative benefits. At the age of 70 regular screening may be ceased. In Canada, the recommendations are used as guidance to be used in discussions with patients. Some women may place a higher value on avoiding cervical cancer and would want to undergo more frequent or earlier screening. While others may prefer to follow the screening guidance. United States The US Preventive Services Task Force sets the screening guidelines in the United States. The US recommendation incorporates high-risk HPV testing, which can help detect high-grade cervical lesions by identifying strains more likely to cause cervical cancers. They recommend the following: Screening begins at age 21-29 and should be followed up every 3 years with cervical cytology. In women aged 30-65, it is recommended to screen every 3 years with cervical cytology and every 5 years with high-risk human papillomavirus testing or every 5 years HPV testing in combination with cytology. The USPSTF recommends against screening in those under the age of 21 and over the age of 65 and those who have had a hysterectomy. United Kingdom The UK has its own set of recommendations through the NHS Cervical Screening Programme. The NHS has also begun including HPV testing in its assessment. Cervical samples will be tested for high-risk Human Papillomavirus to help identify individuals more at risk for developing cervical cancer and implement treatment earlier. Their screening is recommended to begin at age 25 to 65. For those aged 25-49, screening is offered every three years. For those aged 50-64 years of age, it is recommended every five years. What about for those who have had an abnormal Pap previously? Screening guidelines differ if you have previously had an abnormal Pap and HPV has been detected. If your Pap test was abnormal, you were likely referred to a gynecologist for a colposcopy. A colposcopy allows for a better view of the cervix and biopsy. Depending on your level of cell changes and health history, your doctor will recommend a treatment course of action or to watch and wait. In those that have previously tested positive for HPV or had abnormal Paps that turned normal, your doctor will likely recommend follow-up testing a year after a normal result. HPV infections can recur, so it is important to stay on top of testing to see if cell changes recur over time.  The Benefit of Early Detection Deciding when and how often to screen for cervical cancer and HPV, should be discussed with your medical doctor. Early detection has been beneficial in reducing our overall rates of cervical cancer. However, extra screening has also added anxiety and unnecessary procedures to those whose infections would have regressed within 12-36 months. Moreover, detecting infection early also allows for earlier intervention with immune supports like Papillex and lifestyle changes like an anti-inflammatory diet, stress reduction, and exercise.
May 02, 2022
4 min read
The Pros and Risks of LEEP

The Pros and Risks of LEEP

Adrienne Hill-Strathy
If you have previously had an abnormal Pap or tested positive for the human papillomaviruses (HPV), your doctor might have recommended a procedure to help clear the abnormal cells. Several conventional interventions are available to address HPV and cervical changes. These procedures aim to remove abnormal tissue and cells in order to prevent progression into cancer. An HPV diagnosis can be confusing. Adding a potential surgical procedure into the mix may add to your concern, confusion, and anxiety. We hear you; we would want to know the risks, potential harms, and procedural effectiveness as well. Here, we lay out the pros and cons of LEEP and other common conventional treatments for cervical dysplasia so you can be better informed about your options and what is best for your health. First, a bit about HPV HPV is the most common sexually transmitted infection around the world. So common that up to 80 percent of sexually active individuals will contract HPV at some point in their lives. Out of the hundreds of different strains of HPV, around 15 have been identified as high-risk. These high-risk strains are associated with cellular changes on the cervix. If these cell changes persist over time, there is a risk that they may lead to cervical cancer. If you have contracted HPV, do not worry. Up to 90 percent of individuals that contract an infection will clear it within about two years. In individuals that fail to clear the infection, there is an increased risk of developing persistent cell changes that may progress into cervical cancer. Cervical cell changes are monitored using Pap testing. Interventions have been developed to address cell changes before they can occur in individuals who have had abnormal Pap tests and persistent high-grade cervical intraepithelial neoplasia (CIN). Depending on your situation, your gynecologist may recommend a LEEP, conization, cryotherapy, or laser. Here we lay out the pros and cons of each of these procedures. LEEP- Loop electrosurgical excision procedure The LEEP is an excision method used to remove abnormal cellular changes from the surface of the cervix. LEEP is typically recommended in cases of CIN2/3 or persistent CIN 1. During the procedure, you will assume a similar position as you would for a regular pelvic exam. A thin wire loop with an electric current will be inserted into the vagina to remove cells from the cervix.   Pros of LEEP LEEP can be performed in-office. It is quick and generally painless with local anesthesia. The procedure generally takes only 10 minutes. LEEP removes less tissue than other methods, leaving less scarring and changes to the cervix than other methods. The tissue removed during the procedure can be used to confirm the degree of cellular changes. Risks of LEEP LEEP can cause cramping and light bleeding during and after the procedure. The procedure increases the risk of infection, cervical scarring, and changes in sexual function. It is associated with an increased risk of preterm labor and low birth weight. The risk of preterm delivery increases with the depth of LEEP exceeding 10 mm. Effectiveness of LEEP The recurrence rate of CIN 2, 3 after treatment varies depending on one’s age, the severity of the disease, the treatment. The five-year recurrence rate of LEEP is estimated at around 8.1%. Cold Knife Conization Cold knife conization is another surgical excision method used to remove abnormal tissue from the cervix using a scalpel or laser knife. This procedure allows your doctor to further examine the cervical tissue to determine cancerous changes. Conization is used to treat cervical dysplasia and very early cervical cancer. The procedure involves the removal of a cone-shaped portion of the cervix to remove a cervical lesion and the transformation zone. Conization may be used when there are conflicting Pap smear and biopsy findings, there is severe dysplasia, or in the early stages of cervical cancer. Pros of Conization Conization also allows for histologic review of extracted tissue to assess HPV infection and cervical changes. The cone biopsy is used to effectively diagnose abnormalities of the cervix and treat the early stages of cervical cancer. Risks of Conization Side effects of cone biopsy include risk of infection, cramping, and bleeding during and after the procedure. Conization has a higher hemorrhage rate compared to LEEP. The procedure removes more tissue than LEEP and therefore a greater risk of scarring and damage to the cervix. Conization is also associated with an increased risk of preterm labor and low birth weight. Effectiveness of Conization Conization has been found to have the lowest recurrence rate compared to other procedures. The five-year risk of recurrence is estimated at around 4%. Cryotherapy or Laser Cryotherapy and laser are ablative methods used to destroy abnormal cervical tissue. Cryotherapy uses a freezing gas or liquid nitrogen to remove precancerous cells on the cervix. With laser surgery, carbon dioxide is used to destroy abnormal cervical cells. Pros of Cryotherapy or Laser The procedure is quick and can be done in-office, usually taking between 10 and 15 minutes. The risk of preterm labor is not increased as it is with excision methods. Removes less tissue than excision methods. Risks of Cryotherapy or Laser Tissue isn’t available for histologic evaluation, so cells cannot be examined for degree of changes. Can cause mild cramping during the procedure. The procedure may cause vaginal bleeding and lead to infection. Cryosurgery can cause scarring of the cervix, cervical stenosis, which may lead to risks to getting pregnant, staying pregnant, and vaginal delivery.  Effectiveness of Cryotherapy or Laser Cryotherapy was to be least effective at reducing cervical cancer long-term. It was found to have the highest risk of recurrence of CIN 2/3 and invasive cancer after treatment compared to other methods. While each procedure carries some risk, there are benefits to each procedure in reducing rates of cervical dysplasia and cancer. We recommend talking to your doctor about your options and what is best suited for your unique situation. Following any procedure, your doctor will schedule a follow-up Pap smear to monitor cell changes over time. It is important to remember that while the procedures are effective at removing abnormal cellular tissue, they do not remove or suppress HPV activity. Without suppressing the underlying infection, cellular changes can always return, so it is important to continue to monitor the cervix. This continued HPV activity is why supporting the immune system still plays a pivotal role in addressing HPV and preventing long-term complications of the virus.
Mar 04, 2022
5 min read
Letting Go: The Shame of HPV

Letting Go: The Shame of HPV

Adrienne Hill-Strathy
Shame is the intensely painful feeling or experience of believing that we are flawed, and therefore unworthy of love and belonging (Brene Brown, 2012). We all have known and have experienced the discomforting wash of shame at some point in our lives. Under our shame often lies our rooted beliefs and experiences that tell us we are bad. Shame differs from guilt in that our guilt tells us we did something bad, our shame tells us that we are bad. Shame is intense and can lead to secrecy, silence, and judgment. STI’s and Shame From a young age, we have been taught to fear sexually transmitted infections (STIs). Sexual health education, media, and society have all painted the picture that STIs are dirty and disgusting - by that logic, if we catch one, we must be dirty and disgusting, too.  Because HPV is an STI, we often feel ashamed of our diagnosis.  Holding onto shame can prevent us from living a healthy life, and can contribute to stress and unhealthy behaviors that impair our immune system. Letting go of the shame associated with HPV may be foundational to our healing. In this article, we share a few ways you can reframe your narrative to understand that HPV isn’t something to be ashamed about. By releasing our shame, we make space to empower ourselves and others. How to Let go of Shame To let go of the shame of HPV, it is important to clarify a few things about the virus, how it is contracted, and how prevalent it is - with this information, we can begin to change our narrative. Creating a new narrative: the truth about HPV HPV is a virus.  As humans, we are naturally exposed to viruses and other pathogens that live in our environment - this is a part of life. Strains of the HPV family have an affinity for skin tissue in and around the genital or mouth areas. The virus is passed on through skin-to-skin contact with an infected individual. HPV is so common that an estimated 80 percent of women will contract a strain of HPV in their lifetime.  Once infected, the virus makes a home within the human tissue cells. In most cases, the immune system will identify and suppress the virus activity over time leading to no symptoms or complications. In some cases, the virus may proliferate and slowly cause cellular dysplasia that can lead to cervical cancer over many years. Given the large number of HPV strains and high transmission rate of the virus, the best way to avoid exposure includes abstaining from sexual activities or limiting your number of sexual partners. Sexual activity is a significant part of the human experience.  Asking you to suppress your sexuality would be like asking you to stay in your house for the rest of your life to avoid catching a cold. We can aim to prevent infection by avoiding risk factors, but we don’t want to miss out on life! Instead of staying at home, our body has an innate system called the immune system, which we rely on to support and protect us from infection and disease. We can take preventative action by making sure this system is up and running efficiently to protect us against viruses. Now that we understand a little more about the virus, it is time to foster a little empathy. Fostering empathy for yourself: If the root of our shame lies in our feelings of being unworthy of love and belonging, letting go of shame requires a healthy dose of empathy. Empathy involves showing compassion and kindness to ourselves, which can feel unnatural and uncomfortable at first. Imagine talking to yourself like you would talk to a young child or a close friend. How would you speak to them in a similar situation? I would imagine it is different from how you talk to yourself, because we are often harshest to ourselves. Remind yourself that you are not to blame, you are not unworthy, and you are deserving of care. Self-compassion and empathy is a continuous practice.  Name it to tame it One of the most powerful tools we can use to reduce our shame is to talk about it. When we can name our shame, we tame our shame.  So many women suffer the HPV diagnosis in silence but find that when they do speak up they can connect with so many others who are experiencing the same thing. Speaking up about our shame is a vulnerable and emotional risk. With that risk lies the power of vulnerability - it creates space for others to feel less afraid, less alone, and less ashamed. When we don’t talk about these things, we can unintentionally breed shame. Try opening up to someone you trust. Turn to a trusted friend, family member, or counselor - someone who can hold space for you and just listen. We know that talking to a partner can be scary and intimidating, but have found that many who have opened up about their sexual health with their partners often find it brings them closer. Speaking your truth also allows for a chance to practice being your most honest and authentic self. Shame has a powerful weight on each of us, and we all experience it at some point. Often, the shame associated with HPV is rooted in our misunderstanding of the virus and the narrative we have created around contracting sexually transmitted infections.  Remember that shame also does not help you and it does not help others. Be kind to yourself and show yourself compassion - your vulnerability can give others the courage and strength to let go of shame as well. Sources: https://www.ted.com/talks/brene_brown_listening_to_shame?language=en
Jul 26, 2021
4 min read

Example subheading

Subscribe & Save

  • Savings of up to 20% off
  • Plus Enjoy Free Shipping to US / CA
  • Switch or Pause anytime
  • Peace of Mind