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The Role of Nutrition in Cervical Dysplasia
Victoria Gasparini
Cervical dysplasia, characterized by abnormal changes in the cells of the cervix, is a condition that can potentially progress to cervical cancer if left untreated. Medical interventions such as colposcopy and even the "watch and wait" method, are common when diagnosed with dysplasia of the cervix, but there's an additional step we can take to help manage this, reducing our long term risk for cervical cancer and enhancing our health and well-being on all levels.
At Papillex®, we have consistently emphasized the notion that merely "watching and waiting" for our health to deteriorate before taking action is insufficient. Our conviction is well-supported by compelling data. The abundance of evidence linking nutrition to cervical health and dysplasia suggests that it could very well be the intervention you've been looking for.
Nutrition principles to follow
Emphasize the use of antioxidant-rich foods
Antioxidants are powerful compounds that help protect our cells from damage caused by free radicals. Studies suggest that oxidative stress may play a role in the development and progression of cervical dysplasia. Including antioxidant rich foods in your diet can help combat oxidative stress and support cervical health. Colorful fruits and veggies, like berries, citrus fruits, dark leafy greens, bright bell peppers, eggplant and tomatoes are all excellent sources of antioxidants.
Increase intake of folate and other B vitamins
Folate, along with other B vitamins like B6 and B12, are crucial for DNA synthesis and repair. Research suggests that low levels of folate may be associated with an increased risk of cervical dysplasia. Incorporating folate-rich foods such as leafy greens, legumes, citrus fruits, and fortified grains can help ensure adequate intake. Additionally, a balanced diet that includes lean meats and fish, with moderate amounts of dairy (if tolerated) can help provide these essential nutrients, as well.
Up your Vitamin C
Vitamin C is another crucial nutrient for immune function and collagen synthesis. Studies have shown that higher vitamin C levels are associated with a lower risk of cervical dysplasia and progression to cervical cancer. Citrus fruits, strawberries, kiwi, bell peppers, and broccoli are all excellent sources of vitamin C that can all be easily incorporated into your daily meals.
Get those healthy fats in
Incorporating healthy fats into your diet is essential in hormone regulation and overall health. Opt for sources such as avocados, nuts, seeds, fatty fish and olive oil. These fats provide important nutrients and contribute to a well-rounded and nourishing diet. Reduce your intake of saturated and trans fats as these tend to be more inflammatory.
If you're thirsty, you're already dehydrated!
Proper hydration is vital for overall health, including cervical health. Drinking an adequate amount of water helps maintain optimal cell function and supports the body's natural detoxification processes. Non-sugary electrolyte beverages can also help you achieve a more robust amount of minerals. Aim for at least eight glasses of water per day and reduce consumption of sugary beverages.
Aug 07, 2023
2 min read
Perineum Sunning & HPV: A Trend with Scary Consequences
Victoria Gasparini
Social media can be a beautiful place of empowerment, knowledge, community-building and sharing of experiences that help bring us closer together, but there are downsides. Access to information at our fingertips invites the potential of dangerous trends disguised as “health” or “wellness” advice.
One newer trend circulating the web is called “perineum sunning” and it comes with a set of dangerous potential complications, especially for those with HPV.
What is perineum sunning?
The perineum is a small area of thin skin between the anus and the vulva in females, and the anus and the scrotum in males. This thin patch of skin is highly sensitive and delicate to the sun, with many blood vessels and nerves that provide both nutrition and sensation to the genitals.
Because this skin is so incredibly delicate, it is fairly controversial to expose it to the sun (especially without sunscreen), even for just short periods of time.
So, why are people doing it?
The trend of exposing the perineum to direct sunlight was popularized by influencers and even some celebrities online, and is said to be derived from a taoist practice. These influencers claim that by exposing such a delicate area of skin to UV light, you can give your body an intense dose of natural vitamin D, which in turn gives you a massive energy boost - "better than coffee." They have also mentioned that from a traditional Chinese medicine perspective, perineum sunning can stop "qi" (life force energy) from leaving the body, helping us to store this energy in the body instead.
Is there any research to support these claims?
Absolutely none.
Our bodies do create vitamin D from the sun which is necessary for supporting the entire body and its many complexities. But we can (and do) get this exposure without stripping down and exposing our backsides to the sunlight. In fact, just 15 minutes in the sun (without sunscreen) gives us a boost of vitamin D. We can also safely get these doses or “boosts” of the essential vitamin through safe and effective supplementation at the recommendation of your doctor.
The energy boost that these influencers claim comes from perineum sunning will come from just regular sunlight exposure, regardless of the location on your body. There is no evidence to support perineum sunning has any health benefits. There is evidence, however, that it comes with a host of dangerous potential risks - especially for those with HPV, which we discuss below.
At Papillex®, we believe in using health and wellness with an evidence-based lens which focuses on safety, research and ancient practices. With that being said, this trend is not something we recommend.
Perineum sunning and HPV: What’s the connection?
In addition to the potential for a painful and unsightly sunburn, skin cancer is among the greatest risks of tanning the perineum, even for just a short period of time. In fact, according to dermatologist, Angelo Landriscina, MD., “it compounds on the skin cancer risks presented by Human Papillomavirus (HPV) infection.
HPV is a significant risk factor for squamous cell carcinoma (SCC) in the genital region. Combining the presence of HPV with sun exposure to the genital area, specifically the perineum, greatly increases your risk for the development of SCC - which also tend to be more aggressive when in the anogenital region, compared with elsewhere on the body. This is because SCC in this region has a greater chance of metastasis (or spread) which means that they can move to other organ systems, leading to potentially more serious complications and even death.
What can we do instead?
If you’re looking for lifestyle changes you can implement for better energy, sleep, mood and creativity - look no further then the following evidence-based lifestyle practices that have worked for years:
Meditation and breathing exercises
Yoga, pilates and stretching
Regular exercise
Walking in sunlight
Forest bathing
Grounding (barefeet in the grass or sand)
Supplemental vitamin D and B vitamins
Avoid excessive caffeine, especially in the afternoon
Eat lighter meals later in the day
Opt for higher protein and fibre-rich foods
Herbal remedies like rhodiola or ginseng
Rest
To conclude:
Exposing your derriere to UV light carries potential risks that significantly outweigh any benefits reported by influencers with no scientific background. For the sake of your health, choose sure-fire lifestyle practices like the ones listed above, instead.
And if you really still wanna try it, please use plenty of SPF.
Jul 10, 2023
3 min read
Victoria Gasparini
What is Licorice Root?
Licorice root, also known by its latin name as Glycyrrhiza glabra, is a very popular medicinal herb traditionally used globally for centuries for a variety of conditions:
Soothe gastrointestinal irritation
Support the body’s response to stress and help with recovery from burnout
Cough
Anti-inflammatory
Immune modulation
Infections
Its breadth of actions and effectiveness have made it an invaluable tool in traditional herbal medicine, and is extensively researched. The most important active ingredient in licorice root is called glycyrrhizin, or glycyrrhizic acid. Studies have shown that much of its medicinal properties are due to this compound. Since one of the common side effects of glycyrrhizin is slightly increased blood pressure, many combinations that don’t rely on it as the active ingredient will have a de-glycyrrhizinated version, or DGL, such as in formulas to help with stomach irritation. Licorice is also a very important herb in Traditional Chinese Medicine, where it is often included in herbal formulation as a ‘driver’ to complement the other herbs and help deliver them to the right Channels in the body. One of the many uses for Licorice root has been for infections, such as H. pylori and the Herpes Simplex virus (HSV) which causes cold sores and herpes.
How does Licorice help with HSV?
The compounds in licorice root have been shown in laboratory studies to prevent the virus from adhering to healthy cells, thereby preventing the virus from infecting them. It also appears to be able to directly inactivate the virus as well.
Moreover, what makes this herb a potentially great choice for HSV, is its ability to stimulate and modulate the immune system. It is anti-inflammatory and immune-modulating, which means it will help the different immune cells to mature and function properly, so they spend less time causing unwanted inflammation, and more time keeping invaders like HSV at bay.
Those who are suffering from cold sore or herpes outbreaks may also benefit from its adaptogenic properties. An adaptogen is a substance that helps the body cope with stress by shifting the nervous system away from the Fight of Flight mode, and into a calmer state. Chronic stress can cause more frequent and more severe cold sore and herpes outbreaks, so managing stress is an important consideration, where adaptogens like Licorice can be of use.
Safety
Generally, Licorice root is not considered hazardous and has been used medicinally for centuries all over the world. There are a few things to know however, because some adverse effects are possible, most often seen with very high and prolonged doses. Those who have high blood pressure should not take licorice root, or at least consider the DGL version. Same goes for anyone who suffers from electrolyte imbalances such as hypokalemia, is taking thiazide diuretics, cardiac glycosides, and/or has heart or kidney conditions. As always, speak to a qualified healthcare practitioner before starting any new treatments.
Jun 21, 2023
2 min read
Understanding HPV: Taking Steps Towards Optimal Health
Victoria Gasparini
Human Papillomavirus, otherwise known as HPV is a common sexually transmitted infection that affects both men and women. Unfortunately too many of us are told to “watch and wait” when we receive an HPV diagnosis. The good news is, there is actually another way. While we don’t have a way to cure HPV, there are several proactive steps you can take to manage the condition and promote healing. Let’s dive into a step-by-step guide to prevention, management and healing.
Step 1: Schedule regular pap smears and HPV testing
Regular pap smears and HPV testing are crucial for early detection and monitoring of any changes in cervical cells. These screenings can help identify any abnormal cell growth or persistent HPV infections, allowing for timely interventions and appropriate treatment if necessary. Consult with your healthcare provider to establish a screening schedule that aligns with your specific needs.
Step 2: Practice safe sex
Consistently practicing safe sex can reduce the risk of contracting and transmitting HPV. Though condoms and other barrier methods do not completely prevent the spread of HPV, they can help minimize the chances of exposure to the virus. HPV can be transmitted through skin to skin contact, so it is important to protect both yourself and your partner.
Step 3: Focus on nutrition and lifestyle choices
A healthy diet and lifestyle can significantly support your immune system in fighting HPV. Incorporate a nutrient-rich diet that includes plenty of fresh fruits and veggies, whole grains, lean proteins, and healthy fats. Emphasize foods high in antioxidants, vitamin C, and immune boosting nutrients. Minimize processed foods, added sugars, and unhealthy fats, as they can impair immune function and increase inflammation.
Step 4: boost immunity with physical activity
Regular exercise not only improves overall health but also boosts immune function. Engage in moderate-intensity activities such as brisk walking, jogging, cycling, or swimming for at least 150 minutes per week. Exercise helps reduce inflammation, enhances circulation and strengthens your body’s defense mechanisms, all of which contribute to managing HPV more effectively.
Step 5: manage stress levels
Stress can have a negative impact on your immune system, making it important to incorporate stress-management techniques into your routine. Explore activities such as yoga, meditation, deep breathing or engaging in hobbies that help relex and rejuvenate your mind and body. Prioritizing self-care and finding healthy ways to cope with stress can promote healing and overall well being.
Step 6: Quit smoking
Smoking weakens the immune system and increases the risk of developing complications from HPV. If you smoke, take steps to quit or seek professional help to overcome tobacco addiction. Quitting smoking will not only improve your body’s ability to heal but also reduce the risk of other health problems.
Step 7: stay informed and seek support
Educate yourself about HPV, its transmission and available treatment options. Stay up to date with reliable sources of information. Reach out to support groups, online communities where you can connect with others who have similar experiences and share valuable insights.
Jun 12, 2023
2 min read
Victoria Gasparini
Human Papillomavirus (HPV) is a common sexually transmitted infection that affects millions of people worldwide. While there is no cure for HPV, adopting a healthy lifestyle and focusing on nutrition can play a significant role in boosting the immune system and supporting your body’s natural healing processes. Let’s explore the power of nutrition in healing HPV and discuss the key dietary strategies you can implement into your routine today to support your immune defences and promote overall well-being.
Incorporate Antioxidant-rich foods
Including a variety of antioxidant rich foods into your diet is crucial when it comes to healing HPV. Antioxidants help neutralize the damaging effects of free radicals in the body, reduce inflammation, and support immune function. Include plenty of colurful fruits and vegetables such as berries, citrus fruits, leafy greens, broccoli, and bell peppers in your daily meals.
Prioritize foods rich in vitamin C
Vitamin C is known for its immune-boosting properties. It helps strengthen the immune system and supports the body’s ability to fight off infections. Incorporate foods like oranges, kiwis, strawberries, papayas, and bell peppers into your diet to ensure adequate intake of vitamin C.
Focus on cruciferous veggies
Cruciferous veggies such as broccoli, cauliflower, kale, and brussel sprouts are packed with nutrients that can enhance your body’s natural defense mechanisms against HPV. They contain compounds like sulforaphane that have been found to have anti-viral properties.
Include foods high in Omega 3 fatty acids
Omega 3s possess anti-inflammatory properties and support immune health. Incorporate foods like fatty fish (salmon, mackerel, sardines), chia seeds, flaxseeds, and walnuts into your diet to increase your omega-3 intake.
Probiotics for a healthy gut flora
Maintaining a healthy gut microbiome is crucial for overall health and immunity. Include probiotic-rich foods like yogurt, kefir, sauerkraut, and kimchi in your diet to support gut health and enhance immune function.
Avoid processed foods and sugars where possible
Processed foods and added sugars weaken the immune system and promote inflammation. Limit your consumption of processed foods, sugary snacks and beverages to create an optimal environment for healing.
Stay hydrated
Proper hydration is essential for overall health and supports the immune system. Drink plenty of water throughout the day to help flush out toxins and maintain optimal bodily functions.
Jun 05, 2023
2 min read
Andrographis for Herpes Infections?
Victoria Gasparini
The virus that is responsible for cold sores and genital herpes is called the Herpes Simples virus, or HSV. There are two subtypes – HSV-1, which most often causes cold sores on the face, and HSV-2, which is usually the genital type. HSV infections are so common, that it is estimated the 90% of the world’s population have at least one of the types. While most people will not suffer any severe consequences from the infection, there are some who will develop serious issues, and since it’s so contagious and ubiquitous, treatment and prevention have become important issues.
Many medications and natural substances have been studied to see if they have any impact on the herpes virus. There are quite a few compounds that have been found to have promise. One of them has been used in Asian medicine for centuries, and has now also been studied in laboratories as a potent antiviral herb – Andrographis panniculata.
Clinical studies have demonstrated that Andrographis is effective at treating upper respiratory viral and bacterial infections. It also appears to have promising effects as an anti-parasitic, and anti-fungal. In other words, Andrographis may well be an invaluable partner for the immune system in fighting off a whole host of invaders. It does that primarily though compounds called andrographolides, which appear to be able to have a variety of interactions with both pathogens (to disable them), and with our immune cells (to support them).
Lab studies have shown some very promising results that support andrographolides for HSV infections. It appears that these compounds can prevent HSV from replicating, and can even have some viricidal activity. Given how well-known Andrographis panniculata is as an antiviral and immune herb, and the excellent safety profile it possess, it makes for a valuable partner in the defence against herpes infections.
May 16, 2023
1 min read
Ingredient Spotlight: Folate and HPV
Victoria Gasparini
What is folate?
Folate, or its synthetic form, folic acid, is a member of the B vitamin family. It’s a water-soluble vitamin that is heavily involved in many key processes in the body.
Folate is essential for the production of red and white blood cells and other important cells that help to convert food into energy and make DNA. Folate also plays an important role in the reproductive tract and is needed to maintain a healthy pregnancy.
Our bodies cannot make folate on their own so we rely on nutrients in our diet or via supplementation to achieve adequacy. Research on HPV has begun to highlight a strong association between folate deficiency and cervical dysplasia, emphasizing the importance of incorporating more folate-rich foods into our diet as well as taking a quality supplement.
What’s the difference between folic acid and folate?
Folate differs from folic acid in the way that it gets converted in the digestive tract. Folate is immediately converted into the active form of B9. Folic acid, however, enters the blood stream and passes through the liver and other tissues in order to be converted.
Folic acid is thought to be better absorbed, however, it is metabolized at a slower rate, which means more can accumulate and linger in the system and may lead to excess. Folate, on the other hand, will be excreted if too much is consumed.
Folate deficiency
Folate plays a critical role in the body so when it is lacking, it can lead to suboptimal health but it is not always easy to know when you are low in B9. Some symptoms include unexplained fatigue, anemia, muscle weakness, shortness of breath, difficulty focusing, brain fog, headaches, and heart palpitations.
Deficiencies in folate can cause something called megaloblastic anemia, which is when your blood cells form in an improper shape. This hinders their ability to function correctly in your body. Folate is especially important for pregnant women, as deficiencies can cause neural tube defects in a growing fetus.
Benefits of folate consumption
The average adult is recommended to take 400mcg of folate daily. Although folate is best known for preventing neural tube defects in the fetus, newer research is showing benefits in cancer prevention, including breast, bladder, cervical, ovarian and even pancreatic cancers.
Folate is involved in reducing homocysteine levels, which elevations of this can lead to heart disease, folate intake can reduce your risk for heart disease. Recent research is also finding a connection between adequate intake of folate for the reduction of autism spectrum disorder, dementia, Alzheimer’s and even depression.
Food sources of folate:
Dark green leafy veggies
Broccoli
Black-eyed peas
Green peas
Liver
Asparagus
Brussel sprouts
Avocado
Fortified grains
Folate and HPV
Folate in one of the several key nutrients studied in relation to HPV.
Folates role in HPV is likely related to its methylation cycle which ensures our genes are functioning normally. Current research highlights the relationship between low levels of folate in the blood and high risk of HPV infection through promotion of cervical dysplasia development.
Studies have found that individuals with a folate deficiency have an increased risk of positive HPV status, as well as an increased risk of progression to cervical or oral cancer. Whereas women with higher plasma folate and B12 levels with HPV-16 positivity were 60-75% less likely to be diagnosed with moderate cervical dysplasia.
All in all, an extensive amount of research supports the statement that folate plays a protective role in HPV progression to cervical cancer.
May 02, 2023
3 min read
Victoria Gasparini
Having a healthy immune system has been top of mind for many of us in the last few years, and for good reason. Many of us have heard of, or tried, a trick or two to try and improve immune function, especially during cold and flu season, but few of us are sure if they really work. Vitamin C is certainly a very popular one.
The reason Vitamin C is so well known as an immune booster comes early research that demonstrated that those who do not have sufficient vitamin C in their diets, end up suffering from a variety of maladies, one of which is a weakened immune system and increased susceptibility to infection.
Vitamin C supports the immune system by several mechanisms: it can protect the integrity of epithelial cells, which would make it harder for pathogens to enter, it can accumulate in certain white blood cells and improve the way they move and defend against pathogens, it can modulate the inflammatory response, reduce the amount of histamine released, and it is also a potent antioxidant that can minimize cellular damage from oxidation.
Another aspect is that during an infection, there is an increase in the need for vitamin C by the body, and since it is a water-soluble vitamin that cannot be stored, levels can drop quickly resulting in a deficiency. For this reason, studies have shown that supplementing Vitamin C during infections can replete the levels and help the body recover a bit faster, and ameliorate the severity of infections, such as colds, flus and pneumonia.
It also doesn’t take a whole lot of Vitamin C in order to have sufficient levels from the diet, it just has to be a steady, daily supply. A supplement need not necessarily provide a high dose of vitamin C to ensure that the average person has an adequate level of vitamin C. It’s also quite easy to get plenty of Vitamin C through foods, such as citrus, kiwi, berries, bell peppers, and greens.
Apr 17, 2023
1 min read
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