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Red Algae for Cold Sores and Herpes
Jenny Henderson
Marine algae, or seaweed, families are often distinguished from each other very broadly by their colour. There are green algae, brown algae, and red algae. Quite a bit of research has been devoted to these groups because they seem to poses a variety of compounds that have a lot of promise in medicine. It seems that these marine plants that some cultures have been eating for centuries have real potential therapeutic benefits, some of which could be of real interest for those suffering with cold sores and herpes.
What makes red algae special?
The red and brown algae have been of special interest for many of their potential actions. These include being anti-inflammatory, immune modulating, antiviral, anticancer, anticoagulant, antioxidant, and more. One of the their main features are compounds called sulfated polysaccharides (SPs). These large, complex molecules have the ability to physically interact and influence various immune factors and microbes to have a desired health outcome. There is a huge variety of SPs from many species of algae, and it seems that any one of them seems to carry the potential to be of great medicinal importance. Fucoidan is one such compound from brown algae for example, and the some examples of researched red algae include Gigartina skotssbergii and Chondrus crispus.
How can red algae help cold sores and herpes?
When it comes to the Herpes Simplex Virus (HSV), laboratory studies have shown benefit there too. HSV is highly prolific, common, and easily transmissible human virus that can cause cold sores (HSV-1) as well as genital herpes (HSV-2). Since it effects so many people, and because it is so contagious (even when the infected person has no symptoms), any substance that has the potential to modify its life cycle will be of interest. SP’s are one such group of substances.
SP’s from red algae appear to be have multiple mechanisms against viruses such as HSV:
They can have a direct virucidal action, meaning they may damage the virus itself
Inhibit the virus’s ability to enter healthy cells
Inhibit its ability to replicate
Improve the host immune response
As more and more research is being conducted on these impressive compounds from algae, it will not be surprising to see further benefits being uncovered. The seaweeds themselves are considered safe, as many of them are consumed by humans as part of traditional diets, and the SP’s themselves appear to have an excellent safety profile.
Simplix harnesses the power of marine algae | Respond with Confidence
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680640/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528127/
Aug 05, 2022
2 min read
Proven Ways to Strengthen your Immune System this Summer
Victoria Gasparini
There are nearly 150 types of HPV, and thankfully, 90% of cases tend to resolve within a few years of infection. This is because the immune system does an impeccable job of clearing the virus. For others, the virus can lay dormant, not having any major implications on your health. However, some cases of HPV are higher risk, and put us at an increased chance of developing cancers of the cervix, throat, and more. One of the best things you can do for your health after receiving an HPV diagnosis (or before receiving one, because prevention is key), is to build and strengthen your immune system so it can adequately clear or suppress the virus. Thankfully, there are many ways we can do this.
First Things First, Know your Modifiable Risk Factors - and Eliminate Them.
There are many lifestyle changes that have a significant impact on your immune health and on your body's ability to clear a virus. For instance, smoking and excessive alcohol consumption are both factors that increase your risk of abnormal pap smears and HPV progression.
Research finds that smoking tends to increase prevalence of HPV infections by way of suppressing immune function and up-regulating inflammation. Additionally, smoking causes DNA damage and increased cellular proliferation, resulting in a higher incidence and susceptibility to HPV infection, and an increased risk of cancers of the cervix, head and neck. An in-vitro study found a potential link between carcinogen benzo(a)pyrene (in cigarettes) and abnormal cervical cells.
Research also finds that both excessive alcohol consumption and acute binge drinking can increase incidence of persistent HPV and associated symptoms, by disrupting and suppressing immune function. When assessing how alcohol impacts our ability to fight infections, it is important to look at the GI tract. Alcohol's first point of contact is in the gut before entering the bloodstream. With nearly 80% of our immune system residing in the gut, it’s no wonder that alcohol has an impact on immunity.
Alcohol acts as a disruptor to the gut epithelium, damaging T cells and neutrophils in the GI tract thereby facilitating the leakage of microbes through the damaged gut barrier and into circulation. Studies find that it might not only be excessive drinking, but also acute binging of alcohol that has the ability to suppress the immune system, affecting our ability to fight infections like HPV.
Add Science-backed Nutrients to your Diet
Carotenoids
Carotenoids are a colourful class of compounds including lutein, lycopene and zeaxanthin. These orange, yellow and red pigments are naturally occurring in many fruits and veggies such as carrots, squash, bell peppers, mangoes, kale and spinach, to name just a few. Carotenoids play an essential role in modulating immune function and higher levels of carotenoids in the diet are linked with an increased clearance of HPV, especially in early stage infections. Additionally, carotenoids play an essential role in disease prevention, including cancers.
Sulforaphane
Sulforaphane is a powerful antioxidant that aids in detoxification, among other benefits. Sulforaphane is found in broccoli, cauliflower, cabbage and arugula, with the highest amounts in broccoli sprouts. When we consume foods with sulforaphane, it breaks down into two metabolites - DIM and I3C. These compounds are powerful cancer fighters. In fact, researchers have even coined the phrase “green chemoprevention” in relation to sulforaphane's anti-cancer properties. Epidemiological studies emphasize sulforaphanes role as an alternative agent in cancer prevention.
Folate
Our immune system is greatly affected by folate deficiencies. Animal studies have found that folate deficiency causes alterations in the thymus, resulting in decreased ability for T lymphocytes to target pathogens, as well as decreased antibody response to various pathogens. Science has found an association between folate deficiency and cervical dysplasia.
Vitamin C
Vitamin C has many crucial functions to protect the health and integrity of our cells. Studies find that vitamin C intake reduces risk of progression of high-risk HPV to cervical cancer, and can improve cervical dysplasia. Vitamin C is able to neutralize pathogens and inflammation, helping our cells perform their jobs effectively. A study in the journal of infectious diseases finds that risk of persistent HPV was lower in those with higher intakes of vitamin C. Additionally, studies have found a link between an oral intake of 1000mg of vitamin C per day and a shortened duration of genital wart presence, and a decreased rate of occurrence compared to controls.
Selenium
Selenium is a crucial mineral, required for hormone production and balancing oxidative stress. Viral infections may increase our body’s requirements for selenium because of the increased production of reactive oxygen species (ROS). Experimental animal studies have found that selenium may have anti-cancer activity in cervical cancers induced by HPV infection, with epidemiological studies finding that cervical cancer patients have decreased tissue concentrations of selenium. Additionally, a randomized, double-blind clinical trial of 58 Iranian women with biopsy indicated CIN1, found that 200mcg of selenium daily vs. placebo for 6 months demonstrated a regression of CIN1 compared with control. Due to the many mechanisms of selenium on the immune system such as its protective and anti-viral properties, selenium may aid in both treatment and prevention of HPV, and potentially cervical cancers induced by HPV.
All of these nutrients (and more) can all be found in therapeutic dosages in Papillex.
Manage your Stress
Studies continuously find a connection between stress and its impact on immunity, which is supported in pathogenesis and persistence of HPV infections. You cannot always control stressful events from occurring, but you can manage perceived stress through methods of talk therapy, finding good friends to chat with, getting adequate sleep and nutrients, and getting outside in nature. Reducing perceived stressors can help with HPV disease management and progression and is an important part of any HPV treatment plan.
An HPV diagnosis can be overwhelming and scary. The good news is, there are many lifestyle and dietary changes that can aid in the healing of HPV. Building and strengthening your immune system is a great place to start.
May 30, 2022
4 min read
Top 5 Overlooked Foods for Supporting Immune Health
Adrienne Hill-Strathy
At Papillex, we are all about focusing on the factors we can control to positively impact our overall health. With that philosophy in mind, today we’re talking about food!
Food plays a powerful role when it comes to supporting our immune health. The array of micronutrients we obtain from our food is necessary for the immune system to mount and sustain a response against pathogens and invaders like the human papillomavirus (HPV).
Consuming a diverse, whole-food diet is number one in getting our supply of vitamins, minerals, and other phytochemicals. We’ve outlined a few of our favorite foods that can support our immune system on a daily basis.
Citrus fruits
Many of us jump to citrus fruits when it comes to supporting our immune system--for good reason! Citrus fruits like grapefruit, oranges, lemons, and limes are a great source of vitamin C, magnesium, B vitamins, potassium, phosphorus, magnesium, and copper.
Vitamin C in particular plays an important role in many cellular immune functions. The micronutrient has been found to help stimulate immune molecules like neutrophils, which help identify and clear away invaders. Vitamin C has been found to help decrease the severity and duration of colds and flu. Vitamin C can be depleted due to pollution, smoking, infections, and other diseases that increase oxidative stress. Studies have also shown that higher levels of Vitamin C might help reduce cellular changes due to HPV.
Citrus is also a source of phenolic compounds and terpenes. These antioxidants have anti-cancer and anti-inflammatory properties. These compounds and Vitamin C work together to have a synergistic action in supporting your immunity.
Consuming whole citrus fruit (not the juiced form) is also a good source of fiber. Fiber helps support a healthy gut microbiome, which is intricately connected to our immune system.
Cruciferous vegetables
Cruciferous vegetables are also known as the Brassica family, they include some of our favorites--broccoli, Brussel sprouts, collards, red cabbage, kale, and asparagus. These crunchy vegetables contain phytochemicals that are high in antioxidants called isothiocyanates. They are also rich in sulfur, folate, vitamin K, and vitamin B6. Regularly consuming cruciferous vegetables can help support DNA repair. Sulfur also helps recycle the antioxidant glutathione.
The Brassica family also contains a rich source of sulforaphane, which is broken down into two powerful antioxidants, Indole 3 carbinol, and DIM. The compounds have been found to have anti-cancer properties and help regress cervical dysplasia. DIM is one of the ingredients found in Papillex.
Cruciferous vegetables also benefit gut health due to their high fiber content, phytonutrients, and other vitamins and minerals. Lightly cooking these dense vegetables can help make them easier to digest and be utilized by the body.
Ginger
We have all tasted the warm, healing properties of ginger. Ginger has been used for centuries around the world in teas, dishes, and as a medicinal compound. The pungent rhizome contains the compounds gingerol, shogaol, and paradols.
The anti-inflammatory and antioxidant properties of ginger have been found to benefit a range of conditions including degenerative disorders, digestive health, nausea and vomiting, diabetes, and cancer. The antimicrobial properties of ginger also help treat infectious diseases. The research suggests the anti-cancer properties of ginger come from its inhibitory effects on cell proliferation and cell death. Ginger can also suppress inflammation and DNA damage. Studies have shown that ginger can play a role in many cellular pathways that impact the prevention and treatment of cervical cancer.
Garlic
Garlic is another dietary staple, used for centuries for its pungent flavor and many health benefits. A superfood for many reasons, garlic is chock-full of nutrients, amino acids, and fibers. It contains calcium, iron, magnesium, selenium, zinc, and vitamins B1, A, and C.
Garlic’s medicinal properties come from its concentration of sulfur-containing compounds like allicin and ajoene. Allicin helps support the immune system by reducing inflammation and stimulating immune defenses. The compound gets activated when garlic is chopped. Once in the digestive tract, allicin helps inhibit the growth of pathogens it has even been found to protect from certain bacteria like Helicobacter pylori.
The compounds found in garlic also possess anti-cancer effects. Ajoene has been found to trigger cell death in leukemic cells. Compounds in garlic have also been studied for their role in inhibiting mammary, melanoma, colon cancer cell growth. Research into its effect on liver, prostate, bladder, and lung cancer is evolving.
Garlic also supports healthy gut flora. Garlic contains a prebiotic fiber called inulin that helps feed the growth of good gut bacteria.
Mushrooms
We couldn’t complete our favorite immune-supporting foods without mentioning mushrooms. Regularly consuming mushrooms like shiitake and white button, offer a supply of many therapeutic compounds including polysaccharides called beta-glucans. Beta-glucans help inhibit inflammatory molecules while stimulating immune receptors and molecules to defend against pathogens and viruses.
Mushrooms are also a rich source of B vitamins, which help protect the heart and regulate the nervous system. They also contain copper and potassium.
A study researched participants that consumed 5 or 10 grams of shiitake mushrooms daily for a month. They found an increase in the production of T-cells and natural killer cells. Consuming mushrooms also increased the expression of receptors. The participant’s gut health was also impacted, with an increase in sIgA, a marker of healthy gut immunity.
Of course, immune-supportive nutrients and phytochemicals are found across the food rainbow. Ideally, a diet rich in diverse plant and whole foods will support a healthy immune response. We hope this list offers a little extra inspiration for your next grocery haul.
Apr 12, 2022
4 min read
Adrienne Hill-Strathy
Inflammation is the body’s natural response to injury and infection. Without the natural inflammatory response, we would not fair very well!
When inflammation occurs, immune molecules are recruited to the site of injury or invasion to release other immune cells (cytokines, hormones, and white blood cells). These immune cells help repair and restore the body to optimal, healthy function.
However, inflammation can also cause harm.
If the inflammatory response is stimulated too much and for too long, chronic inflammation occurs. During prolonged inflammation, the balance between oxidants and antioxidants is thrown off causing oxidative stress. Oxidative stress promotes the release of more inflammatory molecules. These reactive oxygen molecules damage proteins, cells, and DNA, which increases the risk of diseases and cancers.
This inflammatory response is thought to contribute to the progression of HPV infections to cervical cancers.
Inflammation and cervical health
We know that the immune system is a key factor in regressing HPV infections.
Studies have found inflammatory molecules assist the virus to integrate and proliferate into an individual’s tissues. This means that the more inflammation present, the easier it is for viruses to infect our tissues. Inflammation leaves our cells more vulnerable to further damage.
HPV itself also drives inflammation. The viral particles produced by the HPV (E6, and E7) are also inflammatory and drive more inflammation which further decreases the level of antioxidants, our main weapons against oxidative damage. Together these processes allow HPV to persist.
What increases inflammation?
Chronic inflammation is caused by multiple factors. Some factors we have little control over like infections and injury. Other factors are lifestyle-based like diet, nutrient levels, environmental toxins, stress, and lack of sleep. Fortunately, we do have some control over these factors.
How to tame the flame
Eliminate inflammatory triggers
Reducing exposure to known inflammatory triggers like smoking and alcohol is number one in lowering our overall load. Processed foods, refined sugar, and hydrogenated oils can also be pro-inflammatory. We also know smoking increases the risk of HPV and cervical cancer.
Fuel up on antioxidants
Antioxidants are some of our best sources of inflammation-fighting molecules. Obtaining antioxidants is best done through the diet. With 80 percent of the immune system located in the gut, so what we put into our bodies in the form of food directly interacts with the immune system. Plant-based whole foods offer our greatest source of antioxidants. Aim for 8-10 servings of colorful fruits and vegetables each day. Rotate your veggies often to optimize the unique nutrients and antioxidants in different plant foods.
Supplementation can also play a role in supplying antioxidants. By consuming a greater ratio of antioxidants, we can reduce chronic inflammation. Studies find intake of antioxidants like vitamin A, vitamin E, and vitamin C can neutralize free radicals and are associated with a preventative effect on cervical cancer.
The star players
Some antioxidants have potent disease-fighting properties than others. Our favorites include
Glutathione
Glutathione is best known for its powerful antioxidant activities. The compound is composed of three naturally occurring amino acids, cysteine, glutamic acid, and glycine.
Glutathione can help repair cellular damage caused by oxidative stress and supports the liver in detoxifying hormones and toxins. Studies have found glutathione levels to be low in individuals with cervical cell changes. We can support the body’s natural production of glutathione through supplementing NAC, a natural form of cysteine. Vitamin C, methyl folate, selenium, and curcumin also support glutathione production.
Green tea extract
Green tea contains powerful polyphenols, called EGCG, that have been found to play a role in regressing HPV infections. The antioxidants in EGCG inhibit the cell changes that occur in cervical cancer.
Several studies have found supplementing green tea extract has anti-viral and anti-infective effect that stimulates the immune system. The compound can also be used topically to clear genital warts. To obtain the therapeutic amount of green tea extract, drinking a cup of green tea isn’t enough. Supplementing offers a much stronger dose. We recommend taking 300-600 mg a day.
Indole-3-Carbinol (I3C) and diindolylmethane (DIM)
I3C and DIM are superfood antioxidants found in the broccoli family. 3C and DIM are produced in the stomach after consuming cruciferous vegetables. The compounds have been found to help naturally support and repair DNA damage and reduce the risk of cancer.
One study evaluated oral DIM treatment in individuals with CIN 2 or 3 cervical lesions scheduled for LEEP procedure. Those in the treatment group took 2 mg/kg/day of DIM for 12 weeks. The placebo took a rice bran pill for 12 weeks. At the 6 months follow-up of the study, 84% of the treatment group had improved findings on colposcopy and 85% didn’t require a LEEP. However, no statistical significance was found between the treatment and placebo.
While it is unclear if DIM treatment alone can clear HPV, its powerful antioxidant capabilities in combination with other nutrients and support can contribute to our overall HPV defense.
Medicinal mushrooms
Medicinal mushrooms are another natural compound that has been used for centuries to support the immune system and inflammatory processes. Mushrooms contain active compounds called polysaccharides.
These compounds can inhibit chronically elevated inflammatory molecules like IL-6, prostaglandins, and leukotrienes. Glucans are a type of polysaccharide that stimulates the production of immune molecules like natural killer cells and cytokines. These cells help the immune system clear away unwanted invaders.
Reishi mushroom is commonly used for immune support. It has been found to have anti-inflammatory properties in melanoma and breast cancers. Active Hexose Correlated Compound or AHCC is another mushroom extract that contains a high level of alpha and beta-glucans that modulate the immune system. AHCC has been found to support immune support in cancers and viral infections.
Nov 29, 2021
4 min read
Sulfated Polysaccharides and HPV
Adrienne Hill-Strathy
Within the world of plants and fungi lie a vast array of medicinal compounds. Sulfated polysaccharides are powerful therapeutic compounds being explored for their anti-viral activity. These polysaccharides are shown to have potent anti-viral effects against viruses like the human papillomavirus (HPV) and the herpes virus (HSV).
Sulfated polysaccharides include compounds like heparin, cellulose sulfate, and dextran sulfate. Structurally, these compounds look very similar to heparan sulfate, an HPV cell-attachment factor. These compounds are found to inhibit papillomavirus and herpes infections due to their ability to block the viruses from attaching to healthy cells.
These polysaccharides also contain potent anti-inflammatory and antioxidant properties that help support cellular health and prevent tumor progression.
Where can you find these potent polysaccharides? Sulfated polysaccharides can be found in some species of medicinal mushroom as well as marine plants like red and brown algae.
Red Algae – Irish Moss (Chondrus crispus)
Irish moss is a type of seaweed or algae that is found on the Atlantic coast in Britain, Europe, and North America. The moss is rich in the sulfated polysaccharide carrageenan. You might know carrageenan from the back of your almond milk or yogurt. It is commonly used as a stabilizer and emulsifier in food products. The carrageenan found in common packaged foods is chemically processed and may even have negative health effects. However, consuming the moss in its pure form offers a range of beneficial vitamins and nutrients. Keep reading for a recipe.
In addition to its rich carrageenan content, Irish moss is also rich in other minerals like iodine, important for thyroid health. It also contains omega-3 fatty acids, which can reduce the risk of heart disease and high blood pressure. The moss also contains a carotenoid called fucoxanthin, which benefits blood sugar regulation and acts as an antioxidant, which we know is important for fighting HPV. Irish moss has been consumed for centuries and was used as a nutrient supply during times of famine.
Carrageenan acts as a potent HPV inhibitor by blocking HPV from binding to its attachment sites. Considering condom use is minimally effective in preventing HPV infection, carrageenan is being explored as a topical microbicide to be used preventatively against HSV, HIV, and HPV. The inhibitory effect appears to be strongest for HPV compared to HSV and HIV. Topical applications were found to be safe and well-tolerated, reporting no increased risk of reproductive tract infections or irritations. So far, carrageenan-containing sexual lubricants have been found to be effective at blocking HPV16.
Brown Algae – Fucoidan
Brown seaweeds contain a sulfated polysaccharide, called fucoidan. Fucoidan is a sulfated alpha L-fucan that has been found to support the immune system, reduce inflammation, and have an impact on blood pressure and infection. Animal studies have shown fucoidan to have a protective effect against liver injury by suppressing inflammatory mediators and increase the production of liver-protective enzymes. The anti-viral activity of fucoidan comes from its natural killer cell stimulation which promotes immune modulation and antitumor effects.
Brown algae also contain fucoxanthin, an antioxidant that gives algae its brown color, as well as other microminerals like iodine for thyroid health.
Fucoidan in brown seaweeds has been reported to possess anti-viral activities against viruses like HIV and HSV. The compound acts by inhibiting virus and entry and replication. More human studies are still needed to support its effects, but the compound could be used preventatively to reduce viral infections.
Lentinus Edodes- Shiitake mushroom
Shiitake mushrooms are one of the most well-known mushroom species. Medicinally, the shiitake mushroom is shown to be effective in the treatment of prostate cancer, can help lower high cholesterol, stimulates the activity of immune cells, and has antiviral and antibacterial properties.
The potent medicinal properties come from their high polysaccharide content of Beta-D-glucans. These glucans have been found to enhance the number of immune cells and have antiviral activity against the poliovirus and herpesvirus.
The beta-D-glucans found in shiitake aid in slowing tumor growth and kill viruses and other microbes.
Agaricus Blazei- Almond Mushroom
Another medicinal mushroom rich in polysaccharides is Agaricus Blazei, also called Agaricus subrufescens. Agaricus is a Brazilian basidiomycete often consumed as food or in tea to help with emotional stress, high cholesterol, diabetes, and gastric disorders.
Agaricus contains active compounds that have repeatedly been shown to activate the immune system and prevent the herpes virus from attaching to and infecting healthy cells. The compound also has anti-inflammatory and antioxidant properties, helping maintain the overall health of the cells.
Reaping the many therapeutic benefits of mushrooms isn’t as easy as eating sauteed mushrooms. Medicinal compounds must be extracted through water or alcohol-based decoctions. These powerful extracts are then taken in tinctures or powdered form.
What are the risks to consuming sulfated polysaccharides?
While generally quite safe for use, mushrooms like shiitake may cause an elevation in white blood cells, upset the stomach, and skin inflammation. Agaricus extracts can cause hypoglycemia, nausea, diarrhea, and upset stomach. Few have also reported liver damage and allergic reactions.
Because seaweeds contain iodine, there is a risk of consuming too much iodine and disrupting thyroid function. Sea vegetables like algae may also be exposed to environmental contaminants like arsenic and mercury. Make sure to purchase these supplements from a reputable source. Algae should not be taken with anticoagulant drugs like warfarin and heparin.
Given the immune stimulatory effects of sulfated polysaccharides, supplements should be taken with caution in individuals with autoimmune or immune system conditions. We always recommend seeking advice from a health care provider before starting any supplement or treatment.
Image from: https://divascancook.com/how-to-make-sea-moss-gel-recipe/
How to reap the benefits of Irish Moss
Irish moss can be bought in raw form or cultured into a gel. The moss can then be used topically or ingested. If taken orally, add 1 heaping tablespoon into a smoothie with frozen mangoes and dates.
2 oz of raw Irish moss
1700 ml of spring water
To make:
Wash moss thoroughly in filtered water.
Soak 2 ounces of dried Irish Moss on the counter in 1700 ml filtered water for one day.
Simmer on low until a gel is formed.
Irish moss has minimal taste, so it is perfect to blend into smoothies, juices, and soups or strews.
Store in the refrigerator for up to 2-3 weeks or kept frozen.
Nov 15, 2021
5 min read
Seven Steps to Healthier Habits
Adrienne Hill-Strathy
When it comes to taking care of our health, daily habits are key. It is the consistent things we do every day that add up to enhance our overall wellness and prevent disease.
Habits are powerful because they become automatic behaviors that we do with minimal thought or effort. Over time, these small efforts accumulate and have a significant impact. For instance, most of us brush our teeth twice a day without much complaint or question, but this little action has a huge impact. Brushing helps to prevent cavities and supports our oral health and digestive system.
Habits can also be harmful. Smoking, drinking, overeating, negative self-talk, or too much time on technology can have negative impacts on our health over time. When forming new habits, we want to do our best to engage in the things we know will benefit our wellbeing and reduce harmful behaviors.
When it comes to supporting the immune system to defend against HPV, habits play an important role. Even if you already live a healthy lifestyle, we can all benefit from adopting an extra healthy habit or two.
So, how do you create healthier habits and make them stick?
First, start by identifying what health goals you want to achieve
Before making any lifestyle change it is important to understand your why. Health will mean different things for each of us so understanding why you want to change will help guide the habits you target.
For example, you may want to support your body against HPV. With that goal in mind, you may want to quit smoking, incorporate an extra serving of green leafy vegetables into your diet, or go to bed earlier to get 7-8 hours of sleep. Your goal may be to feel more at peace. Habit for that may look like saying no to more engagements or setting aside time to meditate each morning. Spend some time identifying what you want and then brainstorm how you think you can get there.
Start small
Often when we are trying to make lifestyle changes, we can get overwhelmed by making too many big changes too quickly. When we feel overwhelmed, we are less likely to follow through with our intended actions. Remember to slow down and start with something small and achievable.
Try setting a time and place to complete your new habit. For example, “I am going to go for a walk every day after dinner”, is more realistic than “I am going to walk 5 km a day”. This helps keep your habits flexible and takes the pressure off. It also helps creates a ritual around the new habit which brings us to our next tip.
Creating rituals
Daily rituals are a great way to start implementing a new behavior into your routine. A helpful way to do this is to pair it with something you already do.
Let’s use brushing your teeth again because most of us do that daily. You may be trying to take new supplements to support your immune system. After brushing your teeth in the morning, you could take your supplements. Place your supplement container near your toothbrush so you are easily reminded. Soon, you will naturally pair teeth brushing with taking your supplements and a new habit is formed.
You could also try creating a ritual before bedtime, when putting your clothes on in the morning, or drinking your morning cup of coffee or tea. Take note of things you do every day and then see how you can pair the new behavior with what you already do.
Checking in through reflection
Things don’t always go as planned. Setting aside time each week to reflect on how you are doing and adjust accordingly can help you stay on track.
For example, schedule a Sunday evening check-in to write down how you did this week on your goals. Consider what went well and what you could do differently. Then plan accordingly for the next week. Maybe your goal was too ambitious - that is okay! Ask yourself, what could make it a little easier this week? Try rating how likely you would be to follow through on a scale of 0-10 (10 being very likely, 0 being not at all). If you score below a 7, that’s a sign to bring it back a level and make it easier.
Setting reminders
We all have busy lives and get caught up in things. Setting alarms, reminders, or scheduling in your habits helps you stay consistent. Maybe you want to set a reminder on your phone to take your supplements or drink water throughout the day. Use your calendar to schedule times to exercise, rest, or meal prep. That way even if you have a busy schedule, you can account for those healthy habits into your routine.
Accountability
Having someone to help hold you accountable for your health goals can support your success! Whether that’s a friend, family member, support group, partner, or practitioner, it’s helpful to have someone you can check in with. It can be especially helpful to find someone that will adopt healthy habits with you to encourage you when you’re not feeling up to it.
Be kind to yourself
Lastly, and most importantly, remember to show yourself compassion. Changing behaviors can be challenging. We are not going to be perfect all the time. Aim for doing the best you can. Put in the effort and be gentle with yourself on the rest - tomorrow is always a new day. One small setback doesn’t mean you can’t get up and try again! You can do this!
Oct 18, 2021
4 min read
Christine Chung
Remember when your mom told you to eat your apples and oranges to fight colds and flu? She was onto something!
Vitamin C does it all - boosting energy, improving skin quality and mood, supporting iron absorption, and functions as an antioxidant and immune support.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays an important role in human health. Vitamin C is an essential vitamin for humans, as we are unable to make it on our own. This makes it very important to get enough of this crucial vitamin through our diets or supplementation.
Vitamin C is most known for its role in fighting colds and flu. However, this vitamin is also essential for maintaining the structure and function of our skin tissues. It is involved in the creation of collagen for your skin and fuel for your cells and neurotransmitters. It is also a strong antioxidant, meaning it neutralizes toxic substances in your body.
This powerful vitamin is also an important player in supporting HPV infections.
Benefits of Vitamin C
The mechanism behind many of these benefits comes from Vitamin C’s role in managing oxidative stress. Oxidation occurs when the body breaks down proteins and cells, creating free radicals. These free radicals contribute to cellular damage. Vitamin C (an antioxidant) combats oxidative stress by neutralizing free radicals.
These antioxidant effects help protect connective tissue and form collagen layers in our skin tissues. Vitamin C also supports the immune system by neutralizing pathogens and inflammation which helps immune cells perform their job effectively.
New research sheds light on the connection between Vitamin C status and cancer risk. The study found that Vitamin C from fruits and vegetables was associated with a lower risk of cancer by decreasing the formation of carcinogens in your body.
Vitamin C levels are a good way to measure a healthy lifestyle and can be associated with heart health and decreased risk of strokes.
Let’s not forget the good old-fashioned common cold. Many people take Vitamin C at high doses to prevent colds, or shorten the duration and decrease the intensity of colds. Vitamin C has an anti-histaminic effect at high doses, which is likely to help with colds as well as allergies.
Vitamin C Deficiency
Vitamin C deficiency is famous for causing scurvy back in the days where men would be on ships for long periods, or during times of war and famine. Surprisingly enough, scurvy has been seen more recently in some university student populations.
The most common cause of Vitamin C deficiency is due to poor diet, alcoholism, anorexia, or smoking. Because Vitamin C is widely obtained from fruits and vegetables, it takes several months of poor nutrient intake for severe deficiency to develop.
Vitamin C deficiency can present with symptoms such as fatigue, malaise, and inflammation of gums.
Because vitamin C is an important component of collagen production, deficiency can result in skin conditions like keratosis pilaris, where rough, bumpy skin appears on the back of the upper arms and thighs. Skin may also appear dry, damaged, and bruise easily.
Vitamin C deficiency may also lead to slow-healing wounds, joint pain and it may contribute to iron-deficient anemia by reducing the absorption of iron from plant-based foods and negatively affecting iron.
How much Vitamin C do I need?
Vitamin C can be easily obtained through eating a fruit and vegetable-rich diet.
The recommended daily intake of Vitamin C is about 75 to 90mg. One kiwi contains about 75mg of vitamin C, an orange 83mg, and Brussel sprouts 70mg of vitamin C. Taking an additional 500mg in supplement form can provide an added positive effect.
The Vitamin is considered quite safe, the tolerable upper intake of vitamin C is around 2000mg a day for adults.
Food Sources
Food sources of Vitamin C includes:
Citrus fruits, including lemons, oranges, grapefruit, kiwi)
Bell peppers (specifically red and green)
Broccoli
Strawberries
Brussels sprouts
Tomatoes
Cantaloupe
* It’s important to remember that Vitamin C content may be decreased with heat and prolonged storage.
Remember that significant amounts of vitamin C in food are lost during high-temperature cooking, and during prolonged warming (i.e. keeping meals warm at 75°C for 4 hours). To get the most vitamin C intake from food, cook foods at lower temperatures and for shorter durations if possible, or opt for raw versions of foods when applicable.
Vitamin C’s Role In HPV
Vitamin C’s antioxidant and immune support properties explain Vitamin C’s important role in HPV clearance.
Vitamin C may be useful in preventing and treating a wide range of conditions. Many studies are showing that this Vitamin may even help treat and prevent cervical dysplasia due to HPV infection.
Persistent HPV and Vitamin C
A study in the Journal of Infectious Diseases found that the risk of type-specific persistent HPV infection was lower among women reporting the highest intake of Vitamin C in the study, compared to those reporting the lowest intake.
CIN and Vitamin C
Another study in the International Journal of Gynecological Cancer looked at whether dietary supplements, such as Vitamin C and multivitamins, were associated with cervical intraepithelial neoplasia (CIN), and found that dietary supplements may reduce the risk of CINs in women with high-risk HPV infections.
Natural sources of vitamin C include citrus fruit, cantaloupe, broccoli, Brussels sprouts, cauliflower, and potatoes as well as through supplements like Papillex. Relief of HPV symptoms is another amazing reason to increase your daily intake of fruits and vegetables, and to try taking Papillex!
Vitamin C for Genital Warts
The immune-boosting properties of Vitamin C, along with its propensity for wound healing and creating healthy skin tissue also makes it an important ingredient in treating HPV complications like genital warts.
Studies have found oral intake of 1000mg of Vitamin C per day shortens the time of genital wart remission and marginally decreased the rate of recurrence compared to controls.
Obtaining Your Daily Dose
Obtaining a healthy level of Vitamin C can be as simple as adopting a healthy lifestyle and eating a diet rich in a variety of fruits and vegetables.
For example, having a kiwi with your breakfast, a serving of broccoli at lunch, and fresh tomato sauce at dinner can naturally replenish your body’s stores of Vitamin C. Remember, consistency is key. Eating fruits and vegetables throughout the day regularly is the best way to support our natural stores.
Supplementing with Papillex also offers a serving of 100 percent the daily value of Vitamin C.
Dec 15, 2020
5 min read
Three Antiviral Plants to Fight Infection Naturally
Christine Chung
Plants have been credited with having antiviral and immune-stimulating properties dating back centuries. Herbal medicine was used regularly in Ancient Egypt and China as natural remedies for all sorts of ailments.
Today, studies show that many plants not only have antiviral properties but can also increase the body’s endurance and resistance to a range of biological, chemical, and physical stressors.
Unlike prescription medicines, whose list of potential side effects can be long – antiviral herbal plants and adaptogens often have little to no side effects.
Antiviral Adaptogens
Adaptogens represent one category of herbs that help the body adapt to a variety of stressors. Adaptogens help strengthen the body's resilience to stress on a cellular level.
What makes adaptogens unique is that they:
Cause no harm or additional stress on the body.
Help the body adapt to many and varied environmental and psychological stresses.
Do not have a specific action on the body. They support all major systems like the nervous system, hormonal system, and immune system.
Adaptogens benefit the immune system by stimulating a specific white blood cell called a macrophage.
Macrophages are the first line of defense in eating up or destroying pathogens in the blood and clearing invaders from our system.
Supplementing adaptogens have been found to inhibit viral replication by interfering with the early events of viral adsorption and entry into target cells.
Natural Antivirals For HPV
Are you looking for a natural treatment for HPV?
Below, we have highlighted three antiviral herbs that are key ingredients in our clinically-researched, nutrient-rich supplement designed to optimize your body’s ability to respond to HPV naturally.
Camelia Sinensis - Green Tea Extract
Green tea (Camelia sinensis) has long been known to be a powerful antiviral that benefits the immune system.
Green tea is often used topically for genital warts, and can also be used topically in treatments of cervical dysplasia.
Orally, green tea intake has been associated with a decreased risk of cancer due to its powerful antioxidants. It contains polyphenols, catechins, and flavonoids, which are protective anti-cancer compounds.
Green tea extract provides antiviral activities through active compounds called epigallocatechingallate (EGCG), which have been found to play a critical role in cancer chemoprevention, diabetes, neurodegenerative diseases, stroke, and other biochemical disorders.
In viral infections, EGCG has been found to inhibit the early stage of infections, through attachment, entry and membrane fusion by interfering with viral membrane proteins.
Astragalus
Astragalus root could be your best friend when you’re looking to stop a virus from multiplying.
This powerful immune modulator has been used for centuries to promote resilience in the body. Recent studies have shown this herb’s impact on halting the growth of abnormal cells.
Astragalus does this by stimulating the immune system through enhancing the activity of our natural killer cells and killer t-cells. These immune molecules attack and neutralize invading pathogens in the body.
Astragalus also plays a role in the adaptive immune response. It stimulates the production of white blood cells, antibodies, and production of interferons, which respond to viral invaders.
Ganoderma Lucidum - Reishi Mushrooms
Ganoderma lucidum, more commonly known as Reishi mushroom, has been celebrated for its antiviral properties for more than 2000 years.
Reishi mushroom is a powerful anti-inflammatory and is tied to longevity, improved immune function, and mental clarity. Perhaps that’s why they’ve adopted the nickname “King of mushrooms.” Clinical studies have shown that the use of these medicinal mushrooms has dramatically impacted the clearance rate of HPV, both genital and oral.
Reishi is considered an adaptogenic herb. It contains proteins effective against viruses like herpes simplex and HPV by inhibiting viral replication and adsorption into target cells.
Papillex Supplement
Want to learn more about Papillex™? Check out the What is Papillex page to get the full list of our high potency ingredients.
Sources:
Lyu, Ling, et al. “Effects of Astragalus injection on cervical immortalized epithelial cell growth and its cell cycle regulation mechanism.” Journal of Hainan Medical University 22.4 (2016): 17-20.
Donatini, Bruno. “Control of Oral Human Papillomavirus (HPV) by Medicinal Mushrooms, Trametes versicolor and Ganoderma lucidum: A Preliminary Clinical Trial.” International journal of medicinal mushrooms 16.5 (2014).
Hernandez-Marquez, Eva, et al. “Inhibitory activity of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) on transformed cells by Human Papillomavirus.” International journal of medicinal mushrooms 16.2 (2014).
Nov 15, 2020
3 min read
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