Our Land & Sea formula is the first of its kind. Made with clinically researched mushrooms and wild harvested seaweeds to support the immune system.
Clinically researched botanicals and nutrients in the only formula of its kind.
Immune Support, Made with Integrity
Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free
Made in America






Simplix® contains ingredients with extensively researched immune supporting properties.* It works through multiple pathways to help optimize immunity: supporting viral regulation, stress response, and replenishment of essential nutrients.*
What sets Simplix® apart lies within the synergy of our two natural biomes – Land & Sea. These biomes house immune-boosting agents known as sulfated polysaccharides. These unique compounds, found in edible mushrooms and wild seaweed, form the foundation of Simplix® .
As viruses evolve and we as a society are more engaged in optimizing our immunity, some over-the-counter products are facing scrutiny for their lack of efficacy. Simplix® represents the pinnacle of nutraceutical innovation, a beacon of science-backed immune support.
For the millions of people who experience outbreaks and thought there had to be a better way, we heard you. Simplix® offers revolutionary proactive support through a synergistic formula. *
Published: Biotechnology Reports, Volume 38, 2023
Study Design: The study evaluated the antiviral potential of compounds derived from red algae.
Findings**: Compounds extracted from red seaweeds significantly reduced GFP fluorescence, indicating strong antiviral effects. GFP fluorescence in the study served as a marker for viral activity, with lower fluorescence levels reflecting reduced viral presence.
The effects were dose-dependent, meaning higher concentrations of the algae-derived compounds led to greater inhibition of viral activity.
The algae-based extracts demonstrated notable antiviral efficacy in the study.
Published: Frontiers in Microbiology, May, 2018
Study Design: This study explored the potential anti-influenza activity of shiitake mushrooms in controlled laboratory settings. The research examined their effects on viral replication and immune response in cell cultures.
Findings**:Shiitake mushroom extract appeared to reduce influenza virus replication during the early stages of infection, possibly by interfering with viral entry into host cells.
Published: Frontiers in Immunology, Volume 13, 2022
Study Design: This study investigated the potential immune-regulating effects of fucoidan, a natural compound extracted from the seaweed Laminaria japonica, in a controlled model of weakened immunity. Researchers aimed to understand how fucoidan influences immune function by examining its impact on critical immune components.
Findings**:Fucoidan improved the size and function of key immune organs, such as the spleen and thymus, and enhanced the activity of immune cells like lymphocytes and macrophages.
Fucoidan increased levels of important immune-supporting proteins in the blood, including IL, TNF, and IgG, which are essential for fighting infections and maintaining immune balance.
**The studies cited above refer to the individual ingredients, not our specific product.
Simplix® is designed for individuals looking to support their overall health and immune function. It combines immune-boosting mushrooms from the land and seaweeds from the sea to enhance your body’s response to cold sores, colds, flu, and other viral invaders.
Simplix® can generally be taken with most supplements and medications. However, it’s advisable to consult a healthcare provider, particularly if you are taking immunosuppressants or medications metabolized by the CYP450 2D6 pathway.
Take 2 capsules once daily for maintenance support and 2 capsules twice daily during times of increased need. With or without food. (Or as directed by your health practitioner)
If swallowing supplements is a challenge, Simplix® capsules can be opened and mixed with a small amount of liquid.
The timeline for Simplix® to begin showing effects can vary based on individual health factors. Some people may notice benefits within a few days to a few weeks, while for others, it could take longer. Consistent use is recommended for the best results.
As with all dietary supplements, it’s best to consult with a healthcare practitioner for more specific information regarding your case and needs during post-partum.
Simplix® can be taken short-term as a proactive measure during periods of increased stress or decreased immunity, or it can be used long-term as part of a maintenance regimen for ongoing immune support. It is advisable to periodically review its use with your healthcare provider to ensure it continues to meet your health goals.
Store Simplix® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy. Keep out of reach of children.
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Its definitely made a difference. the only time i had a minor outbreak since I started taking it was during a week when i wasnt taking it regularly. Its truly preventative and even the outbreak i did get, was minor, compared to past outbreaks before taking Simplix. very grateful for this and not needing to take Valtrex much at all anymore.
Some digestive upset at first. Now it's fine. Will keep using in hopes of more improvements.
I have taken Simplix for the past 3 weeks. For one who has experienced continuous outbreaks with short respites while on valtrex, this works! I take 2 tabs three times a day. However, Simplix will only be effective when coupled with a high lysine, low arginine diet. In other words, it is not a silver bullet, diet discipline is essential
It has helped me to manage cold sore breakouts.
Purchased Simplex twice this winter to help add extra immunity during cold and flu season and I was able to navigate through without getting sick.
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