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AHCC®

AHCC® is a mushroom extract obtained from the shiitake mushroom species. Backed by over 30 Human Clinical Studies, it’s proven science for real results.

  • One of the best researched nutritional supplements in the world
  • Stimulates immune response to promote health and wellness* 
  • Supports Natural Killer Cell (NK) activity*
  • Trusted by practitioners globally
  • Can be taken as a top up or for ongoing immune support
Clear

Pure and simple AHCC®

  • No fillers, vegan capsule 
  • High quality sourcing
  • Verified as authentic by 3rd Party Lab
  • Meets or exceeds FDA & Health Canada Standards
  • 60 capsules per bottle 
  • Generally, a serving of 1-3 grams daily is recommended for immune support. Higher servings may be taken to support the immune system in response to more specific conditions. Or as directed by your health practitioner. 
  • AHCC® can be taken with Papillex® synergistically to support the body’s response to HPV. For HPV, clinical trials have shown benefit with 3g of AHCC daily (2 capsules three times a day or 3 capsules twice a day).
  • If swallowing or taking supplements is a challenge, AHCC® may also be taken with food.
  • Consistency is the foundation to better results that last. Some results may be felt immediately but allow your body approximately 3 months to experience the full benefits.

Advanced Immune Support, Sourced with Integrity

Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free

High Quality Immune Support

Support your Innate Immune System*
AHCC® contains polysaccharide compounds called alpha-glucans and beta-glucans. They help promote the innate immune system by supporting the activity of natural killer cells (NK), dendritic cells, and cytokines.

AHCC® is a biological response modifier (BRM) which means it stimulates the immune system to promote health and wellness when the body is under duress.  The glucans in AHCC® can be easily absorbed, allowing quick and effective interaction with the immune system.

AHCC® can modulate, suppress, and /or strengthen the response of the immune system depending on the perceived threat.

AHCC® has been used for many years to support immunity and overall health. Modern science has researched its broad range of immune benefits, from responding to viral infections and cellular integrity to supporting the gut-immunity connection. *

AHCC® is one of the best researched nutritional supplements in the world, with remarkable efficacy and an impeccable safety profile based on over 30 human trials as well as over 100 pre-clinical trials that have been completed at leading global research institutes and Universities.**

100% Pure AHCC®

Shiitake Mushroom Extract
(Lentinula edodes)

Immune Modulation & Response| Supports Natural Killer Cell Activity | Overall Wellbeing*

Shiitake Mushroom Extract (Lentinula edodes)

The data shows that the glucans in AHCC® are adept at stimulating the immune system to promote health and wellness.*
This patented extract is produced by Amino Up Chemical Co. LTD in Japan. Amino Up uses an extensive manufacturing process that involves cultivation, decomposition by enzymes, sterilization, concentration, and freeze-drying, ensuring the safety and efficacy of every batch.

Verified as authentic by Alkemist Labs

AHCC® boosts immune response by supporting various immune cell functions. *

Partner your AHCC® with Papillex®

Your questions,
answered.

What is AHCC®?

AHCC® (Active Hexose Correlated Compound) is a nutritional supplement derived from shiitake mushroom, traditionally used to strengthen the immune system by stimulating the production of white blood cells and enhancing the body’s response to viral infections. Backed by over 30 human clinical trials, AHCC® improves immune function and is manufactured through a controlled patented process by AminoUp Chemical Co. Ltd.

AHCC® by Wellex is designed for individuals looking to enhance their immune health, particularly during times of increased stress, illness, or recovery. It can also support the body’s response to HPV and can be taken with Papillex® for a synergistic effect.

AHCC® can generally be taken alongside other supplements or medications. However, it’s always best to consult your healthcare provider before combining products, especially if you are taking immunosuppressants or medications metabolized by the CYP450 2D6 pathway.

Generally, a serving of 1-3 grams daily is recommended for general immune support. Higher servings may be taken to support the immune system in response to more specific conditions. For HPV, clinical trials have shown benefit with 3g daily (2 capsules three times a day or 3 capsules twice a day). AHCC® can be taken with Papillex® synergistically to support the body’s response to HPV.

The timeline for AHCC® to begin showing effects can vary based on individual health factors. Some people may notice benefits within a few weeks of regular use, while for others; it can take longer depending on individual health factors and the specific health goals of supplementation. It can be helpful to track general health indicators to monitor progress over time.

AHCC® can be taken short-term as a proactive measure during periods of increased stress or potential exposure to infections, or it can be used long-term as part of a maintenance regimen for ongoing immune support. It is advisable to periodically review its use with your healthcare provider to ensure it continues to meet your health goals.

Store AHCC® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy.  Keep out of reach of children.

Real reviews,
real results.

Customer Reviews
4.9 Based on 163 Reviews
5 ★
91% 
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3 ★
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Filter Reviews:
A
02/08/2025
Anonymous
US US

Great customer service

Packaging and experience with customer service was top of the line.

A
02/06/2025
Alma
US US

Finally HPV Free after 6 years

I received an abnormal pap with HPV detected back in 2019. I have been doing nearly year paps since then, with every single one coming back HPV positive. I've had one colposcopy where they took a biopsy, and that experience was some of the worst pain I have ever had in my entire life. I was beginning to feel hopeless, as everyone else appears to clear their HPV within 2 years--why was mine lasting so long?? A friend recommended AHCC, and in my search for it, I came across Papillex. I first ordered the original Papillex bottle and began taking only two tablets of that, not super regularly, about two months before my last pap in the summer of 2024. It came back HPV positive again, and my doctor agreed that I would try a strict regimen of Papillex and AHCC combined until January, when I'd have another pap. Hoping this would be a Hail Mary, I took daily two pills of Papillex and two pills of AHCC, with only missing a few days here and there due to travel. I had another pap end the end of January 2025 and it came back negative. I literally cried. On top of clearing my 6 year fight with HPV, these pills have seemed to boost my immunity in general. I have not gotten sick, even after spending time traveling, at people filled concert halls, and working in health care where everyone around me is dropping like flies to Norovirus. I will continue to take these pills, for their immunity boosting properties. I am also fearful of HPV returning if I stop taking them. If you're doubting purchasing these because of the cost, I am telling you, IT IS WORTH EVERY PENNY!!

3Y
02/06/2025
31 y.
United States United States

You can fix it

Honestly, I’m not sure if it was these supplements but I test positive for hpv and abnormal pap for 6 years ! I fasted for 60* days, liquid fast, I took this and the other pappilex supplement from this company. I searched for a while for what to do because I didn’t want to get worst (hpv) I was supposed to get tested 6 months after my last pap, I tested a year later. I tested negative. 10/10 would recommend but diet change is definitely a part as well. I wanna be anonymous but if somebody is reading this looking for a way to rid your body of it naturally. Get both and try! The body will heal itself! No surgery needed!

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