AHCC® is a patented shiitake mushroom extract for bolstering the immune system. Backed by over 30 Human Clinical Studies, it’s proven science for real results.
Pure and simple AHCC®
Advanced Immune Support, Sourced with Integrity
Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free
Made in America






AHCC® is a biological response modifier (BRM) which means it stimulates the immune system to promote health and wellness when the body is under duress. The glucans in AHCC® can be easily absorbed, allowing quick and effective interaction with the immune system.
AHCC® can modulate or strengthen the response of the immune system depending on the perceived threat.
AHCC® has been used for many years to support immunity and overall health. Modern science has researched its broad range of immune benefits, from responding to viruses and cellular integrity to supporting the gut-immunity connection. *
AHCC® is one of the best researched nutritional supplements in the world, with remarkable efficacy and an impeccable safety profile based on over 30 human trials as well as over 100 pre-clinical trials that have been completed at leading global research institutes and Universities.**
Papillex® is an evidence-based supplement featuring nutrients and ingredients designed to support your immune system in the presence of HPV.* It replaces key nutrients that have been found to be missing and low in people with reduced immunity.* For those seeking specific support, AHCC® and Papillex® are natural partners, creating a complementary effect in helping your body optimize its immune response.
AHCC® (Active Hexose Correlated Compound) is a nutritional supplement derived from shiitake mushroom, traditionally used to strengthen the immune system by stimulating the production of white blood cells and enhancing the body’s response to viruses. Backed by over 30 human clinical trials, AHCC® improves immune function and is manufactured through a controlled patented process by AminoUp Chemical Co. Ltd.
AHCC® by Wellex is designed for individuals looking to enhance their immune health, particularly during times of increased stress, illness, or recovery. It can also support the body’s response to HPV and can be taken with Papillex® for a synergistic effect.
AHCC® can generally be taken alongside other supplements or medications. However, it’s always best to consult your healthcare provider before combining products, especially if you are taking immunosuppressants or medications metabolized by the CYP450 2D6 pathway.
Generally, a serving of 1-3 grams daily is recommended for general immune support. Higher servings may be taken to support the immune system in response to more specific conditions. For HPV, clinical trials have shown benefit with 3g daily (2 capsules three times a day or 3 capsules twice a day). AHCC® can be taken with Papillex® synergistically to support the body’s response to HPV.
The timeline for AHCC® to begin showing effects can vary based on individual health factors. Some people may notice benefits within a few weeks of regular use, while for others; it can take longer depending on individual health factors and the specific health goals of supplementation. It can be helpful to track general health indicators to monitor progress over time.
AHCC® can be taken short-term as a proactive measure during periods of increased stress or potential exposure to infections, or it can be used long-term as part of a maintenance regimen for ongoing immune support. It is advisable to periodically review its use with your healthcare provider to ensure it continues to meet your health goals.
Store AHCC® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy. Keep out of reach of children.
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My husband and I are both using it. I Being retested soon so as far as efficacy I will know how well it works for me soon.
Been 5 months still positive
I want to order 3 bottles at a time but system won’t let me. Also it’s physicallyimpossible to get out of marketing emails. I’ve tried 3 times. As to the effectiveness of the product, I am not sure yet. But since I keep getting repeated emails asking for a review, my review is a little bit frustrated. For the reasons I have stated also I think they should send their packaging without the name of the manufacturer on it. Some people like discreet packaging and that’s not something the company is willing to do.
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