Advanced support in response to HPV

Papillex®

$77.23 CAD $70.21 CAD

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Why watch and wait when you can be proactive? Support your overall wellness with key nutrients for immune and cellular health.*

Pack Size: 1 Bottle

Papillex® helps to:*

  • Optimize your immune system response
  • Encourage cervical cell integrity
  • Set your body up for success by restoring balance
  • Naturally support at every stage, from early proactivity to long term maintenance

Formulated by a leading naturopathic doctor and trusted by health practitioners for over 16 years.

  • Synergistic, clinically researched ingredients that work together for amplified benefits 
  • Clean formula, with whole-food sourced nutrition in clinical servings
  • Featuring ingredients supported by human data, the highest level of scientific confidence  
  • High in Antioxidants A, C, E
  • Meets or exceeds FDA & Health Canada Standards
  • 60 capsules per bottle 
  • Take 2 capsules twice daily when actively responding.  Take 2 capsules once daily for maintenance. With or without food. (Or as directed by your health practitioner.) 
  • For those with difficulty swallowing, the capsule can be opened and the contents mixed with fruit juice or apple sauce (or similar). 
  • Consistency is the foundation to better results that last. Some results may be felt immediately but allow your body approximately 3 months to experience the full benefits. 

Multi-Action Immune Support, Made with Integrity

Made in America | Clean, Evidence-Based Ingredients | 3rd Party Tested | Clinical Servings | cGMP Certified | Doctor Formulated | Filler Free | Gluten & Major Allergy Free

Papillex®
$77.23 CAD $70.21 CAD
$77.23 CAD $70.21 CAD

CLEAN, EVIDENCE-BASED INGREDIENTS

3RD PARTY TESTED

CLINICAL SERVINGS

DOCTOR FORMULATED

FILLER FREE

GLUTEN & MAJOR ALLERGY FREE

CGMP CERTIFIED

MADE IN AMERICA

Proven Science, Real Results

Our immune system is our command center for the body’s defence, reparation, and restoration in the presence of any virus. Optimal immunity is job number one. 

Papillex® offers targeted nutritional support by replacing key nutrients that have been found to be missing and low in people with reduced immunity. It is formulated with a series of evidence-based ingredients that have been shown in multiple research studies to support the body’s response to HPV.*

The ‘watch and wait’ period is a crucial time. Papillex® empowers you to be proactive now instead of waiting to see what might transpire, especially in cases of persistence.

Papillex® offers natural, ongoing daily immune support.

Clinically researched, whole-food sourced ingredients

DNA Health | Antioxidant | Antiviral**

Broccoli Sprout Extract

Indole-3-carbinol, DIM, and sulforaphane are powerful metabolites found in broccoli family vegetables that support DNA health and cervical health.**

Immunity | Cervical Integrity | Anti-Inflammatory**

Reishi Mushroom (Ganoderma lucidum)

The reishi mushroom has been celebrated for its medicinal properties for more than 2,000 years. Studies have shown that it supports the immune system and cervical health.**

Cervical Health | Antioxidant | Anti-Inflammatory**

Lycopene & Carotenoids

Plant compounds that are associated with cervical health. Studies have shown that those with deficient levels of carotenoids are at increased risk of HPV progression.**

Immunity | Cervical Health | DNA Repair **

Folate

An essential B vitamin that supports the immune system and reproductive health. A human randomized controlled trial found that folate significantly impacts cervical health.**

Antioxidant | Immune T-Cell Function | Overall Health**

Vitamin C & Zinc

Research studies conclude that higher levels of these powerful antioxidants support the immune system, oral and cervical health.**

Immune Modulator | Antioxidant | Cervical Health **

Green Tea Extract (Camellia sinensis)

Green tea has long been known as a powerful plant that stimulates the immune system. It has been associated with a positive impact on oral and cervical cell health through its antioxidant effects.**

Cellular Health | Immunity | Antioxidant**

Vitamin E

Vitamin E has been shown in studies to promote cell health and to support the immune system through its antioxidant capabilities.**

Oxidative Stress | Immune Function | Cell Health**

Selenium

Selenium is an essential trace mineral that contributes to oral, cervical and reproductive wellness.**

Immune Stimulator | Antiviral | Cervical Cell Integrity**

Astragalus

This powerful herb has been used for centuries to promote resilience in the body. Recent studies have shown the herb’s impact on the health of cervical cells.**

**The studies cited below refer to the individual ingredients, not our specific product.

Clinically Researched Ingredients

  • Reishi & Immune Modulation 

    Published: Pathogens 

    Study Design 

    In a randomized, double-blind, placebo-controlled trial, 126 healthy adults aged 18–55 took 200mg Reishi-derived β-glucan or placebo daily for 84 days. 

    Findings 

    • CD3+, CD4+, and CD8+ T-cell counts significantly increased after 84 days in the Reishi β-glucan group (p < 0.05). 
    • Natural killer (NK) cell counts and NK cell cytotoxicity improved compared to placebo (p < 0.05). • Serum IgA levels also rose significantly 
  • Lycopene & Oxidative Stress Modulation

    Published: Cureus Journal of Medicine, March, 2021  

    Study Design 

    This in vitro study evaluated the effects of lycopene, alone and in combination with cisplatin, on cervical (HeLa) cells. Over 72 hours, researchers assessed cell viability and measured key protein markers related to cell death, inflammation, and oxidative stress. 

    Findings 

    • Lycopene reduced HeLa cell viability on its own and enhanced the apoptosis effect of cisplatin, lowering cell survival to 37.4% when combined (P < 0.0001). 
    • Lycopene increased pro-apoptotic Bax expression and decreased anti-apoptotic Bcl-2 expression (P < 0.0001). 
    • It also activated Nrf2 (oxidative stress defense) and suppressed NF-κB (inflammation), supporting its role in both antioxidant and anti-inflammatory pathways. 
  • EGCG & HPV Oncoprotein Degradation

    Published: BMC Complementary Medicine and Therapies, Volume 24, 2024 

    Study Design 

    This lab-based study investigated how EGCG, the main polyphenol in green tea, affects the growth and viral activity of HPV18-infected keratinocytes and a vulvar intraepithelial neoplasia (VIN) cell line. The focus was on EGCG’s influence on cell proliferation, HPV oncogene expression and replication. 

    Findings 

    • EGCG was shown to influence the stability of HPV-related proteins (E6 and E7) in laboratory studies using HPV-transformed cells. 
    • It affected expression of viral proteins involved in the later stages of the HPV life cycle in differentiating keratinocytes. 
    • EGCG promoted protein degradation pathways (proteasome-mediated), suggesting a potential mechanism for regulating viral protein levels in vitro.

Strengthen your body’s defences for peak protection with AHCC®.

Power up your Papillex®

AHCC® is derived from the shiitake mushroom and works as a biological response modifier (BRM) to turn up the dial on your immune response.* Early phase clinical trials also show a high clearance rate of HPV infection after 6 months of use.* During times when you believe your immunity to be particularly compromised, AHCC® is the perfect compliment to Papillex.

Papillex® FAQs

Papillex® is designed for individuals seeking natural immune support to assist the body’s response to HPV. It is an evidence-based supplement that helps optimize cervical health in a natural and proactive manner. Papillex has been specially formulated to replenish key nutrients that are often low in individuals with HPV.

Papillex® can generally be taken alongside other supplements or medications however, it’s always best to consult your healthcare provider before combining products especially immunosuppressants, blood thinners, or medications that affect the liver.

It is recommended to consult with your healthcare provider before taking Papillex® to ensure it aligns with your overall fertility plan.

For ongoing maintenance, take 2 capsules daily. During times of active support, take 2 capsules twice daily. If swallowing supplements is a challenge, Papillex® capsules can be opened and mixed with a small amount of liquid.

As with many natural supplements, it may take some time to notice changes in your health. While some people see results sooner, we recommend taking Papillex® consistently for at least 3 months before assessing its effectiveness for you.

In addition to taking Papillex®, it’s beneficial to follow a nutrient-rich diet, emphasizing fruits, vegetables, and whole grains while minimizing processed foods, alcohol, and fried foods. Incorporating regular moderate exercise and staying hydrated and managing stress through practices like yoga or meditation are also important. Additionally, consider drinking more green tea, which is known for its antioxidant properties that support immune health.

Papillex® can be used long-term as part of a comprehensive wellness plan, typically at a lower maintenance dose. However, it’s important to regularly review your use of the supplement with your healthcare provider, especially if there are any changes in your health or circumstances.

Store Papillex® in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy. Keep out of reach of children.

HPV is one of the world’s most common viruses. Our goal is to empower every single person to optimize their body’s immune system response.

Real reviews, real results.

Take it off your to-do list and enjoy

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