Endo Well®
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A thoughtfully formulated blend of evidence-informed nutrients and botanicals designed to support hormone balance, a healthy inflammatory response, and overall reproductive wellness.*
- Hormone Balance Support*
- Inflammatory Response Support*
- Cycle Comfort & Resilience*
Targeted Support Across Multiple Pathways
Hormonal signaling plays a central role in cycle regularity and overall reproductive wellness. Endo Well includes nutrients that support balanced hormone activity and cellular health.*
A healthy inflammatory response is essential for tissue comfort and resilience. This formula includes compounds studied for their role in maintaining balanced inflammatory signaling.*
Magnesium, PEA, Polydatin and Ginger work together to support muscle relaxation and nervous system balance.*
Oxidative stress can influence cellular function. Endo Well provides multiple antioxidant compounds that help protect cells and support overall tissue health*
By supporting hormone balance, inflammatory response, antioxidant defense, and stress regulation, Endo Well helps promote a more balanced internal environment.*
A first-of-its-kind formula
Anti-Inflammatory | Antioxidant | Cellular Repair*
Vitamin E and C
It has been shown in Human Clinical Trials that these vitamins help neutralize free radicals, which supports a healthy inflammatory response and promotes comfort during menstruation.
Anti-Oxidant | Hormone Balancing
NAC (N-acetylcysteine)
An essential amino acid, NAC helps neutralize reactive oxygen species in the pelvic cavity, supporting inflammatory response, overall pelvic health and a healthy tissue environment.**
Anti-Inflammatory | Hormone Balancing | Replenish Nutrients **
Vitamin D
Vitamin D is a prohormone that has an important job modulating inflammation in endometrial cells.**
Muscle Relaxation | Help Manage Discomfort | Replenish Nutrients**
Magnesium
This nutrient has been shown to help ease muscle spasms and cramping.**
Estrogen Metabolism**
DIM (Diindolylmethane)
Supports the metabolism of estrogen, which plays a role in maintaining hormonal balance and cellular health in estrogen-responsive tissues. It has been shown to support pelvic health.**
Pain Support | Antioxidant | Nausea **
Ginger
This natural plant extract helps respond to oxidative stress, maintain tissue health, and support a healthy inflammatory response. It has been shown in clinical studies to ease menstrual discomfort.**
Pain Support | Targets Oxidative Stress | Nervous System Wellness**
Polydatin
A natural polyphenolic compound found in many plants and foods. When combined with PEA, it has been shown in Human Clinical Trials to help support in the presence of chronic pelvic pain and inflammation.**
Pain Signalling | Pain Support | Anti-Inflammatory**
PEA (Palmitoylethanolamide)
A biologically active lipid naturally produced by the body to soothe discomfort. It works by modulating the receptors that signal pain.** It is well researched, making it a suitable option for women focused on reproductive health. **
Calming Adaptogen | Anti-Inflammatory | Stress Reduction**
Ashwagandha
This adaptogenic herb supports a healthy stress response and helps maintain balanced cortisol levels. By promoting immune resilience and supporting a healthy inflammatory response, it helps foster comfort and well-being during the menstrual cycle.**
**The studies cited below refer to the individual ingredients, not our specific product.
Clinically Researched Ingredients
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PEA & Pain Management
Published: International Journal Women’s Health, Volume 11, 2019
Study Design
Thirty symptomatic women with laparoscopic diagnosis of endometriosis and pregnancy desire. Patients were given um-PEA twice daily for 10 days followed by m(PEA/PLD) twice daily for 80 days.
Findings
- Significant improvement in chronic pelvic pain, deep dyspareunia, dysmenorrhea, dyschezia.
- Significant improvement in quality of life and psychological well-being.
-
Ginger and Menstrual Cycle Support & Cramping
Published: Cureus Journal of Medicine, March, 2021
Study Design
This meta-analysis, the highest level of evidence in research, systematically evaluated 4 randomized controlled trials (RCTs) to assess the effectiveness of ginger compared to placebo for pain severity and duration in women with primary dysmenorrhea.
Findings
- Ginger significantly reduced pain severity in primary dysmenorrhea compared to placebo.
- It was found that ginger and NSAIDs were equally effective in pain severity.
-
DIM for Estrogen Management
Published: BMC Complementary Medicine and Therapies, Volume 24, 2024
Study Design
This study looked at how taking DIM affects estrogen levels and metabolism. Researchers compared estrogen levels in urine between two groups—DIM users and non-users —and also analyzed changes before and after starting DIM.
Findings
- Women taking DIM had significant differences in most estrogen levels and metabolites compared to non-users.
- In women who started taking DIM, noticeable changes were seen in key estrogen levels, including estrone, estradiol, estriol, and 16-hydroxyestrone.
- DIM increased the ratio of “healthier” estrogen metabolites (2-hydroxyestrone:16-hydroxyestrone), which indicates better estrogen metabolism.
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NAC as Anti-Inflammatory and Antioxidant
Published: International Journal of Environmental Research and Public Health, March, 2023
Study Design
This prospective single-cohort study evaluated the effectiveness of oral N-acetylcysteine (NAC) in reducing pain and ovarian endometriomas, and its role in fertility improvement among patients aged 18-45 years. Patients received NAC (600 mg, 3 tablets/day for 3 days per week) over 3 months.
Findings
- Pain intensity significantly improved
- Endometrioma size reduced significantly
- Among 52 patients with reproductive desire, 39 achieved pregnancy within 6 months of starting NAC therapy
Your questions, answered.
Endo Well is designed for those seeking advanced endometrial support.
Endo Well can generally be taken alongside other supplements or medications however, it’s always best to consult your healthcare provider before combining products especially blood thinners, or medications that affect the liver.
Endometriosis can impact fertility by causing inflammation, scarring, and hormonal imbalances, which may block fallopian tubes, damage eggs or sperm, or interfere with implantation. Supporting pelvic health, managing inflammation, and hormonal imbalances can help improve fertility outcomes for some individuals.
It is recommended to consult with your healthcare provider before taking Endo Well to ensure it aligns with your overall fertility plan.
As with all dietary supplements, it’s best to consult with a healthcare practitioner for more specific information regarding your case and needs while breastfeeding.
Take 2 capsules twice daily with food, or as directed by a healthcare practitioner.
Consistent use is important to allow your body time to respond. While some individuals may notice changes sooner, we recommend allowing approximately 3 months (3 cycles) for optimal benefits.
Endo Well can be taken long-term as part of a comprehensive approach to endometrial health. However, it is important to periodically review your use of the supplement with your healthcare provider, especially if there are any changes in your health.
Store Endo Well in a cool, dry place, away from direct sunlight and moisture to maintain its efficacy. Keep out of reach of children. The shelf life of Endo Well is typically two years from the date of manufacture.
If you are preparing for surgery, it’s essential to consult your healthcare provider about taking any dietary supplement. Your provider can guide you on whether to pause or adjust your supplement routine, typically 1-2 weeks before surgery, to ensure safety and optimal recovery.
Thoughtfully formulated support for hormonal balance and endometrial health.*
Real reviews, real results.
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