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6 Evidence-Based Ways to Reduce IC Flares and Support Bladder Health

6 Evidence-Based Ways to Reduce IC Flares and Support Bladder Health

Kadia Bielecki
Interstitial cystitis/bladder pain syndrome (IC/BPS) can feel unpredictable. For many women, symptoms may begin with subtle warning signs, such as urinary urgency, bladder discomfort, pelvic pressure, or bloating. Then, seemingly out of nowhere, a full flare can disrupt your bladder, your plans, and your sense of control. While IC flares are not always fully preventable, research suggests that certain dietary, lifestyle, pelvic floor, nervous system, and behavioral factors may contribute to symptom worsening. Identifying your personal triggers and supporting the body more consistently may help reduce flare frequency and improve quality of life.¹ This article outlines six evidence-informed strategies that women with IC, bladder pain syndrome, or mild overactive bladder symptoms can use to support bladder health and reduce the likelihood of symptom flares. Identify and Avoid Food and Beverage Triggers Dietary triggers are among the most commonly reported contributors to IC flares. While every bladder is different, research has found that certain foods and beverages are more likely to worsen bladder pain, urgency, and frequency in people with IC/BPS.² https://www.youtube.com/shorts/eieumSebuZ0 Common dietary irritants may include: Coffee and caffeine Alcohol, especially wine Citrus fruits and juices Spicy foods Carbonated drinks Artificial sweeteners Vinegar-containing foods Some fermented foods Because triggers vary from person to person, a food and symptom journal can be helpful. Tracking what you eat, how much you drink, and when symptoms worsen may reveal patterns over time. Practical tip: Even “healthy” options like kombucha, lemon water, or vinegar-based dressings may trigger symptoms in some people because of their acidity. Rather than eliminating everything at once, consider testing foods slowly and intentionally. 2. Support Daily Bowel Movements and Gut Health The bladder and bowel are closely connected. When constipation occurs, a backed-up colon may increase pressure on the bladder and contribute to urgency, frequency, pelvic discomfort, or flare-like symptoms.³ Supporting regular bowel movements may help reduce pelvic pressure and improve overall pelvic health. Helpful strategies may include: Eating soluble fiber from foods like oats, chia seeds, flaxseed, and cooked vegetables Drinking enough water throughout the day Moving your body regularly Discussing magnesium supplementation with a healthcare provider, if appropriate Addressing underlying digestive issues, such as IBS, if present Healthy bowel function may also support immune balance and reduce unnecessary strain on the pelvic floor. If constipation is frequent or severe, it may be worth working with a healthcare provider to identify the root cause. 3. Regulate the Nervous System Stress does not cause IC, but many people with IC notice that symptoms worsen during periods of emotional stress, poor sleep, trauma activation, or physical overwhelm. Research suggests that IC/BPS may involve nervous system sensitization, meaning the nerves involved in pain, urgency, and bladder signaling may become more reactive over time.¹ ⁴ Nervous system regulation is not about simply “being less stressed.” It is about helping the body shift out of fight-or-flight and into a calmer, more regulated state. Supportive practices may include: Diaphragmatic breathing Mindfulness meditation Gentle yoga Body scans Somatic tracking Humming, gargling, or other gentle vagus nerve-supportive practices Cognitive behavioral therapy or trauma-informed therapy, when appropriate These tools may help reduce symptom sensitivity, improve stress resilience, and support a more regulated pelvic floor and bladder response. 4. Address Pelvic Floor Dysfunction The bladder does not work in isolation. It is part of a complex pelvic system that includes muscles, nerves, connective tissue, and surrounding organs. In many people with IC/BPS, the pelvic floor muscles can become tense, tender, or poorly coordinated.¹ ⁵ Pelvic floor dysfunction may contribute to symptoms such as: Bladder pain Burning with or after urination Pain with intercourse Pelvic heaviness Urinary urgency Difficulty fully relaxing while urinating Symptoms that worsen after sitting for long periods Pelvic floor physical therapy is recommended in IC/BPS guidelines for patients who have pelvic floor tenderness. Manual therapy, myofascial release, and relaxation-based pelvic floor work may help reduce pain and improve urinary symptoms. Strengthening exercises, such as Kegels, may worsen symptoms in people with tight or overactive pelvic floor muscles and should not be used unless recommended by a qualified clinician.¹ Supportive strategies may include: Pelvic floor physical therapy Internal or external myofascial release Gentle hip and pelvic mobility exercises Avoiding prolonged sitting when possible Wearing loose, comfortable clothing during flares Working with a provider trained in pelvic pain 5. Consider Bladder Training for Urgency and Frequency For some people with IC/BPS, urinary urgency can become amplified over time as the bladder and nervous system become increasingly sensitive to normal filling sensations. In certain cases, bladder training may help reduce urgency, improve bladder capacity, and decrease the frequency of bathroom trips.¹ ⁷ Bladder training involves gradually increasing the amount of time between urination rather than responding immediately to every urge. The goal is not to ignore severe pain or force the bladder to become overly full, but rather to gently retrain bladder signaling and improve confidence around urgency sensations. Helpful strategies may include: Tracking your current voiding interval for several days Gradually extending bathroom visits by 5–15 minutes at a time, as tolerated Using diaphragmatic breathing or relaxation techniques when urgency occurs Distracting the nervous system with calming activities while waiting for the urge to pass Working with a pelvic floor physical therapist or healthcare provider for individualized guidance Bladder training is often most successful when combined with pelvic floor relaxation, stress management, and trigger reduction. However, it may not be appropriate during active flares, severe pain episodes, or when urgency is caused by an untreated urinary tract infection or other medical condition. For individuals whose primary symptoms include urgency and frequency rather than severe bladder pain, bladder training may be a useful tool for improving day-to-day bladder control and reducing symptom-related anxiety. 6. Stay Hydrated and Support Bladder Lining Comfort Dehydration can lead to more concentrated urine, which may feel irritating to a sensitive bladder. For some people with IC/BPS, maintaining steady hydration throughout the day may help reduce bladder discomfort and urgency.¹ Helpful hydration tips include: Sip water consistently throughout the day Aim for pale yellow urine rather than dark yellow urine Avoid extreme fluid restriction Avoid overhydration, especially if urine is completely clear all day Notice whether certain beverages worsen symptoms Some people also use soothing herbal teas, such as marshmallow root or corn silk, for bladder comfort. However, herbal products can affect people differently, and not all “natural” remedies are appropriate for sensitive bladders. Certain nutrients and botanicals, including quercetin and aloe vera, have been studied for their potential role in supporting bladder comfort and inflammation balance, though more high-quality research is needed.⁶ Always speak with a healthcare professional before starting any new supplement, especially if you are pregnant, breastfeeding, taking medications, or managing a chronic condition. A Few Common Missteps to Watch For “Natural” Does Not Always Mean Bladder-Safe Some herbs, essential oils, acidic supplements, or concentrated extracts may irritate sensitive bladders. Do Not Assume Every Flare Is IC Urinary tract infections, yeast infections, sexually transmitted infections, kidney stones, and other conditions can mimic or worsen IC symptoms. Testing may be needed, especially if symptoms are new, severe, or different from your usual pattern. Do Not Over-Restrict Your Diet The low-acid or bladder-friendly diet is not one-size-fits-all. Personal tracking can help identify your actual triggers without unnecessary food fear or restriction. Do Not Ignore the Pelvic Floor If symptoms include burning, pelvic pain, pain with intercourse, or discomfort after sitting, pelvic floor dysfunction may be contributing. Final Thoughts Living with IC can be frustrating, painful, and emotionally exhausting. But symptom management often improves when care focuses on the whole person, not just the bladder. By identifying dietary triggers, supporting bowel health, regulating the nervous system, addressing pelvic floor dysfunction, incorporating bladder training when appropriate, and maintaining healthy hydration habits, many women can reduce flare frequency and feel more confident in their day-to-day care. Because every person's triggers and symptoms are unique, tracking patterns and working with knowledgeable healthcare professionals can help create a personalized plan for long-term bladder health. Here's to bladder calm and empowered care. References Hanno PM, Erickson D, Moldwin R, Faraday MM. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment. Journal of Urology. 2015;193(5):1545-1553. American Urological Association. Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome. AUA Guideline. Updated 2022. Shorter B, Lesser M, Moldwin RM, Kushner L. Effect of comestibles on symptoms of interstitial cystitis. Journal of Urology. 2007;178(1):145-152. Interstitial Cystitis Association. Associated Conditions and IC/BPS. Accessed 2026. Lai HH, Krieger JN, Pontari MA, et al. Painful bladder filling and painful urgency are distinct characteristics in men and women with urological chronic pelvic pain syndromes. Journal of Urology. 2015. FitzGerald MP, Anderson RU, Potts J, et al. Randomized multicenter clinical trial of myofascial physical therapy in women with interstitial cystitis/painful bladder syndrome and pelvic floor tenderness. Journal of Urology. 2012;187(6):2113-2118. Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, Rajfer J. Treatment of interstitial cystitis with a quercetin supplement. Techniques in Urology. 2001;7(1):44-46.
Jun 09, 2026
7 min read
Why Am I Always Tired Before My Period?

Why Am I Always Tired Before My Period?

Kadia Bielecki
Understanding PMS Fatigue Feeling Exhausted Before Your Period? You're Not Imagining It If you find yourself feeling unusually tired, sluggish, or mentally drained in the days leading up to your period, you're not alone. Fatigue is one of the most common symptoms associated with premenstrual syndrome (PMS). For many women, the week before menstruation can bring noticeable changes in energy, sleep quality, mood, concentration, and physical performance.¹ While occasional tiredness is normal, recurring fatigue before your period may feel frustrating, especially when it affects work, exercise, relationships, or daily responsibilities. The good news is that there are biological reasons why PMS fatigue happens. Research suggests that hormonal fluctuations, changes in brain chemistry, sleep disturbances, inflammation, and stress responses may all contribute to feeling exhausted before your period.³⁻⁹ Understanding these factors can help you better support your energy levels throughout your cycle. What Is PMS Fatigue? PMS fatigue refers to feelings of low energy, exhaustion, mental fog, or increased sleepiness that occur during the luteal phase of the menstrual cycle. The luteal phase begins after ovulation and lasts until menstruation starts. This is the time when many PMS symptoms appear, including: Fatigue Mood changes Irritability Anxiety Bloating Breast tenderness Food cravings Difficulty concentrating² Research estimates that nearly half of reproductive-age women experience some degree of PMS symptoms, while a smaller percentage experience more severe symptoms that significantly affect quality of life.² For many women, fatigue is one of the most disruptive symptoms. Why Am I So Tired Before My Period? Short Answer Fatigue before your period is likely related to hormonal fluctuations, changes in neurotransmitters, sleep disturbances, inflammation, and increased physiological stress during the luteal phase of the menstrual cycle.³ The Hormonal Connection Throughout the menstrual cycle, estrogen and progesterone levels rise and fall. After ovulation, progesterone increases significantly. If pregnancy does not occur, both estrogen and progesterone decline before menstruation begins. Researchers believe these hormonal shifts influence: Serotonin activity GABA signaling Sleep quality Mood regulation Energy metabolism⁴ Women with PMS and PMDD appear to have heightened sensitivity to these hormonal fluctuations rather than abnormal hormone levels themselves.⁴ This may explain why some women feel only mild symptoms while others experience substantial fatigue, brain fog, anxiety, or mood changes. How Hormonal Changes Affect Your Brain, Sleep, and Energy While hormone fluctuations help trigger PMS symptoms, researchers increasingly recognize that the brain's response to these hormonal changes plays a major role in premenstrual fatigue. Emerging evidence suggests that women with PMS and PMDD often have a heightened sensitivity to normal changes in estrogen and progesterone rather than abnormal hormone levels themselves.⁴ These hormonal shifts can influence brain regions involved in attention, emotional regulation, stress responses, and cognitive performance. Research has identified changes in neurotransmitter activity, including serotonin, dopamine, and GABA, alongside alterations in brain networks involved in executive function and mood regulation.¹¹⁻¹³ As a result, some women may experience: Brain fog Mental fatigue Reduced concentration Forgetfulness Irritability Increased stress sensitivity Feeling emotionally overwhelmed Research also consistently shows that women with PMS often report poorer sleep quality during the late luteal phase of the menstrual cycle.⁵⁻⁷ Common sleep-related symptoms include: Difficulty falling asleep Frequent nighttime awakenings Feeling unrested in the morning Increased daytime sleepiness Reduced sleep quality⁵ One study found that women with severe PMS reported significantly poorer subjective sleep quality during the late luteal phase compared with the follicular phase.⁶ Even when total sleep duration remains similar, disrupted sleep quality can contribute to fatigue, lower cognitive performance, and reduced resilience to stress. This combination of hormonal changes, altered neurotransmitter activity, and sleep disruption may help explain what many women describe as "period brain fog." Symptoms may include: Difficulty concentrating Reduced motivation Forgetfulness Slower thinking Mental fatigue Some studies have found that women with premenstrual disorders experience greater levels of inattention and fatigue compared with women without these conditions.¹ Because the brain requires significant energy to support attention, memory, and decision-making, disruptions in sleep and hormonal signaling may contribute to the cognitive symptoms many women notice before their period. Research suggests that hormonal fluctuations during the luteal phase may influence activity in areas of the brain responsible for attention, memory, planning, and emotional regulation. Studies have found altered activity in the prefrontal cortex and increased reactivity in stress-related brain regions among women experiencing PMS and PMDD.¹¹⁻¹³ This means that "period brain fog" is not simply feeling tired—it may reflect temporary changes in how the brain processes information, regulates stress, and manages cognitive workload throughout the menstrual cycle. Could Nutrient Deficiencies Be Making PMS Fatigue Worse? Potentially. Certain nutrient deficiencies may contribute to fatigue and worsen PMS symptoms. Research has identified associations between PMS symptom severity and lower levels of: Iron Vitamin D Magnesium Calcium Zinc⁸ For example, vitamin D deficiency has been associated with greater risk of severe fatigue and other PMS-related symptoms in some populations.⁸ Low iron stores may also contribute to feelings of exhaustion, particularly in women with heavy menstrual bleeding. If fatigue is severe, persistent, or worsening over time, it may be worth discussing laboratory testing with a healthcare provider. Does Inflammation Play a Role in PMS Fatigue? Researchers increasingly believe inflammation may contribute to PMS symptoms. Emerging evidence suggests women with PMS may experience changes in inflammatory pathways that influence mood, pain sensitivity, stress responses, and fatigue.⁹ Inflammation can affect neurotransmitter production and energy regulation, which may partly explain why fatigue often appears alongside symptoms such as: Headaches Mood changes Body aches Low motivation Brain fog⁹ While more research is needed, inflammation remains an active area of investigation in PMS research. Could Stress and Nervous System Dysregulation Make PMS Fatigue Worse? Possibly. Chronic stress can affect the hypothalamic-pituitary-adrenal (HPA) axis, the body's primary stress-response system. Elevated stress levels may influence cortisol production, sleep quality, mood regulation, and energy metabolism, all of which can contribute to PMS-related fatigue.⁹ Researchers have also observed that women with PMS may experience increased sensitivity to stress during the luteal phase. When combined with poor sleep, high workloads, emotional stress, or inadequate recovery, this may amplify feelings of exhaustion, brain fog, and irritability. Supporting nervous system regulation through consistent sleep, regular physical activity, stress-management practices, mindfulness, and adequate recovery may help improve resilience during hormonal transitions. How Can I Improve PMS Fatigue? Prioritize Sleep Sleep disturbances are strongly associated with PMS symptom severity.⁵ Helpful strategies include: Maintaining a consistent sleep schedule Limiting caffeine later in the day Reducing screen exposure before bed Creating a cool, dark sleep environment Stay Physically Active Although exercise may feel difficult when you're exhausted, research suggests regular physical activity can improve PMS-related fatigue.¹⁰ Exercise may support: Better sleep Improved mood Stress reduction Increased energy levels¹⁰ Even moderate movement such as walking, cycling, yoga, or strength training may help. Support Blood Sugar Stability Large blood sugar fluctuations can worsen feelings of fatigue. Consider prioritizing: Protein-rich meals Fiber-rich carbohydrates Healthy fats Consistent meal timing This may help support more stable energy levels throughout the day. Evaluate Nutritional Status If fatigue is affecting daily life, consider speaking with a healthcare provider about evaluating: Iron status Vitamin D levels B12 levels Other potential contributors to fatigue Addressing underlying deficiencies may improve symptoms. Track Your Cycle One of the most helpful tools is simply identifying patterns. Tracking symptoms for several months can help determine: When fatigue typically begins How severe it becomes Whether symptoms are worsening Which lifestyle strategies help This information can also help healthcare providers assess whether symptoms align with PMS, PMDD, or another condition. When Should You See a Healthcare Provider? Fatigue before your period can be normal, but it should not be debilitating. Consider seeking medical evaluation if: Fatigue interferes with work or school Symptoms significantly affect quality of life You experience severe mood changes Fatigue persists throughout the month Symptoms continue worsening over time In some cases, severe fatigue may be related to PMDD, iron deficiency, thyroid disorders, sleep disorders, or other medical conditions that require treatment.² Frequently Asked Questions Is it normal to be extremely tired before your period? Many women experience increased fatigue before menstruation due to hormonal fluctuations, sleep changes, and PMS symptoms. However, severe fatigue that disrupts daily functioning should be evaluated by a healthcare provider. How many days before my period does fatigue start? PMS fatigue typically begins during the luteal phase, which occurs about 1 to 2 weeks before menstruation.² Can PMS cause brain fog? Yes. Research suggests PMS may contribute to concentration difficulties, mental fatigue, and reduced cognitive performance in some women.¹ Does PMS affect sleep? Yes. Women with PMS frequently report poorer sleep quality, increased nighttime awakenings, and greater daytime fatigue.⁵⁻⁷ Why am I tired before my period even when I sleep enough? Hormonal fluctuations, neurotransmitter changes, inflammation, nutrient deficiencies, and sleep quality disturbances may contribute to fatigue even when total sleep duration appears adequate. Key Takeaways Feeling tired before your period is one of the most common PMS symptoms and is often linked to hormonal changes during the luteal phase of the menstrual cycle. Research suggests fatigue may be influenced by changes in progesterone, estrogen, serotonin signaling, sleep quality, inflammation, and nutrient status.¹⁻⁹ While some degree of premenstrual fatigue is common, severe or persistent exhaustion should not be ignored. Understanding your cycle, supporting sleep, maintaining regular physical activity, and addressing potential nutrient deficiencies may help improve energy levels and overall well-being. References Lee SY, Chen SL, Wang LJ, et al. Insomnia, inattention and fatigue symptoms of women with premenstrual dysphoric disorder. Int J Environ Res Public Health. 2021;18(12):6192. Ryu A, Kim TH. Premenstrual syndrome: a mini review. Maturitas. 2015;82(4):436-440. Baker FC, Lee KA. Menstrual cycle effects on sleep. Sleep Med Clin. 2018;13(3):283-294. Drosdzol-Cop A, Szczepanek M, Chrustek A, et al. Premenstrual syndrome: new insights into etiology and review of treatment methods. Front Psychiatry. 2024;15:1363875. Hachul H, Andersen ML, Bittencourt LR, Santos-Silva R, Tufik S. Does the reproductive cycle influence sleep patterns in women with PMS? Sleep Med Rev. 2010;14(2):107-113. Baker FC, Kahan TL, Trinder J, Colrain IM. Sleep quality and the sleep electroencephalogram in women with severe premenstrual syndrome. Sleep. 2007;30(10):1283-1291. Keshavarz Z, Simbar M, Alavi Majd H. Association between sleep quality and premenstrual syndrome in young women. Sci Rep. 2025;15:90581. Rencz A, Brough L, Thorstensen EB, et al. Effect of nutritional interventions on the psychological symptoms of premenstrual syndrome: a systematic review. Nutr Rev. 2025;83(2):280-302. Li Y, Zhang H, Chen X, et al. Psychological stress dysfunction in women with premenstrual syndrome. Heliyon. 2024;10(20):e16264. Wang X, Zhao Y, Liu H, et al. A systematic review of exercise interventions on negative affect, pain, and fatigue in women with premenstrual syndrome. BMC Womens Health. 2025;25:242. Long J, Wang Y, Li X, et al. The prominent role of the temporal lobe in premenstrual syndrome and PMDD: evidence from multimodal neuroimaging. Front Psychiatry. 2022;13:954211. Odber C, Cocks N, Schaefer A. Menstrual cycle phase modulates emotional conflict processing in women with PMS. Front Psychol. 2013;4:717. Maki PM, Rich JB, Rosenbaum RS. Implicit memory varies across the menstrual cycle: estrogen effects on cognition. Psychoneuroendocrinology. 2002;27(6):725-739.
Jun 05, 2026
8 min read
Creatine for Women: Benefits, Safety, and How to Take It

Creatine for Women: Benefits, Safety, and How to Take It

Kadia Bielecki
Creatine for Women Is Finally Getting the Attention It Deserves For years, creatine was marketed almost exclusively to male athletes and bodybuilders. But emerging research suggests that creatine may offer unique benefits for women across multiple stages of life; from supporting exercise performance and recovery to cognitive function, healthy aging, and even hormonal transitions.¹⁻³ Women naturally store and metabolize creatine differently than men. Research suggests women generally have lower dietary creatine intake and lower endogenous creatine synthesis rates, which may make supplementation particularly relevant for female health and performance.² As interest in strength training, longevity, and metabolic health continues to grow, creatine is becoming one of the most researched and evidence-backed supplements for women. What Is Creatine? Creatine is a naturally occurring compound made from the amino acids glycine, arginine, and methionine. The body produces approximately 1 gram per day, primarily in the liver, kidneys, and pancreas, and additional creatine is obtained through foods such as red meat and fish.¹ About 95% of the body's creatine is stored in skeletal muscle, where it helps regenerate adenosine triphosphate (ATP): the body's primary source of cellular energy.¹ During short bursts of high-intensity activity, creatine helps replenish energy stores more quickly, allowing muscles and other tissues to perform more efficiently. This is why creatine has long been used to support strength, power, and exercise performance.¹ Molecular structure of creatine monohydrate Why Creatine May Be Especially Beneficial for Women While creatine has traditionally been studied in male athletes, newer research highlights several reasons women may uniquely benefit from supplementation. Women appear to have: Lower dietary creatine intake on average Lower endogenous creatine synthesis rates Hormonal fluctuations that may influence creatine metabolism Increased vulnerability to age-related losses in muscle mass and bone density²,³ Researchers have proposed that creatine may support women differently across the lifespan, including during menstruation, pregnancy, perimenopause, and postmenopause.³ 1. Creatine May Support Strength, Lean Muscle, and Exercise Performance One of the most well-established benefits of creatine is its ability to improve strength and high-intensity exercise performance.¹ Creatine increases phosphocreatine stores within muscle tissue, helping regenerate ATP during demanding exercise. This may support: Increased strength output Improved training performance Better recovery between sets Greater training adaptations over time¹ Research in women has demonstrated similar benefits. In a study of collegiate female athletes, women who supplemented with creatine during resistance training experienced significantly greater improvements in upper-body strength compared with placebo.⁴ Importantly, creatine does not directly build muscle on its own. Rather, it may help support the quality and intensity of training, which can contribute to gains in lean muscle mass over time when combined with resistance exercise.¹,³ 2. Creatine May Help Reduce Fatigue During Certain Phases of the Menstrual Cycle Hormonal fluctuations throughout the menstrual cycle influence energy metabolism, recovery, hydration status, and fatigue perception. Emerging evidence suggests creatine supplementation may help support energy availability during phases of the cycle where fatigue is more common, particularly the luteal phase.¹ Researchers have reported that women may experience reductions in fatigue following high-intensity exercise during the luteal phase when supplementing with creatine.¹ Recent studies have also shown that creatine may positively influence cellular hydration and fluid balance across the menstrual cycle, potentially supporting overall performance and recovery.³ Although more research is needed, these findings suggest creatine may offer benefits that extend beyond athletic performance alone. 3. Creatine May Support Brain Health and Cognitive Function Creatine is not only stored in muscle; it is also found in the brain. The brain requires large amounts of ATP to support memory, attention, learning, and mental performance. Because creatine plays a central role in energy metabolism, researchers have explored its potential impact on cognitive function.¹ Studies suggest creatine supplementation may help support: Memory Attention Mental processing Cognitive performance during periods of stress or sleep deprivation¹,³ Some research also suggests women may experience unique cognitive benefits due to hormonal influences on brain energy metabolism.³ While further research is ongoing, creatine's role in supporting cellular energy production makes it an intriguing tool for long-term brain health. 4. Creatine May Support Mood and Mental Well-Being Mood changes and mental fatigue can occur throughout various hormonal transitions, including menstruation, postpartum recovery, and menopause. Researchers have increasingly investigated creatine's potential role in supporting mental health due to its effects on brain energy metabolism.³ Emerging evidence suggests creatine supplementation may help improve mood and may even enhance responses to certain depression treatments when used alongside standard care.³ Although creatine is not a treatment for mental health conditions, researchers continue to explore its role as a supportive nutritional strategy for cognitive and emotional well-being. 5. Creatine May Support Healthy Aging and Menopause After menopause, women experience accelerated declines in estrogen, muscle mass, strength, and bone density. These changes can contribute to: Loss of lean muscle Reduced physical function Increased fall risk Reduced bone strength³ Research suggests creatine supplementation combined with resistance training may help support muscle mass, strength, and bone health in postmenopausal women.³ Some studies have also reported improvements in functional capacity and physical performance in older women who supplemented with creatine alongside exercise programs.³ For women focused on healthy aging, maintaining muscle and strength is one of the most important factors for long-term mobility and quality of life. Is Creatine Safe for Women? Creatine monohydrate is one of the most extensively studied dietary supplements available. Current evidence indicates that creatine supplementation is safe for healthy women when used as directed.¹,³ Common misconceptions include concerns about kidney damage, dehydration, or significant water retention. However, long-term studies have not demonstrated harmful effects on kidney function in healthy individuals using recommended doses.¹ Some women may notice a temporary increase in body weight during the initial stages of supplementation due to increased intracellular water retention. This reflects increased muscle hydration rather than body fat gain.¹ As with any supplement, individuals with underlying medical conditions or those who are pregnant should consult their healthcare provider before beginning supplementation. How Much Creatine Should Women Take? The most studied and recommended form is creatine monohydrate.¹ Common evidence-based approaches include: Daily Maintenance Dose 3–5 grams per day Loading Protocol (Optional) 20 grams per day divided into four 5-gram servings for 5–7 days, followed by 3–5 grams daily¹,³ A loading phase is not required and may increase the likelihood of temporary bloating or gastrointestinal discomfort. Many women choose a consistent daily dose of 3–5 grams, which gradually increases muscle creatine stores over several weeks.¹ Consistency is more important than timing. Frequently Asked Questions Will creatine make women bulky? No. Creatine does not directly cause large increases in muscle size. It may support strength, recovery, and lean muscle development when combined with training, but it does not create the hormonal environment associated with significant muscle hypertrophy.  What form of creatine is most studied? Creatine monohydrate is the most researched and widely recommended form of creatine. It has been extensively studied for its safety, effectiveness, and absorption, making it the preferred choice for most people. Does creatine cause weight gain? Some women may experience temporary increases in body weight due to increased water retention within muscle cells. This is different from gaining body fat.¹ Weight gain and bloating are more commonly reported with high-dose loading protocols, which are not necessary for most people. Any increase in body weight may also reflect gains in lean muscle mass when combined with resistance training. Can women take creatine every day? Yes. Research supports daily supplementation, and consistent intake appears to be the most effective strategy for maintaining creatine stores.¹,³ Is creatine only useful for athletes? No. Research is increasingly exploring creatine's role in cognitive health, aging, recovery, and overall wellness, making it relevant beyond athletic populations.¹,³ The Bottom Line Creatine is no longer just a supplement for athletes. Research suggests it may support strength, recovery, cognitive function, mood, and healthy aging in women across multiple stages of life.¹⁻³ While more women-specific research is still needed, current evidence indicates that creatine monohydrate is a safe, effective, and well-studied supplement that may offer benefits extending far beyond the gym. References Gutiérrez-Hellín J, Del Coso J, Franco-Andrés A, et al. Creatine supplementation beyond athletics: benefits of different types of creatine for women, vegans, and clinical populations—a narrative review. Nutrients. 2025;17(1):95. https://doi.org/10.3390/nu17010095 Smith-Ryan AE, DelBiondo GM, Brown AF, Kleiner SM, Tran NT, Ellery SJ. Creatine in women's health: bridging the gap from menstruation through pregnancy to menopause. J Int Soc Sports Nutr. 2025;22(1):2502094. https://doi.org/10.1080/15502783.2025.2502094 Ellery SJ, LaRosa DA, Kett MM, et al. Dietary creatine supplementation during pregnancy: a review of the current evidence and applications for maternal and fetal health. Amino Acids. 2016;48(10):2199-2212. https://doi.org/10.1007/s00726-016-2199-y Brenner M, Walberg Rankin J, Sebolt D. The effect of creatine supplementation during resistance training in women. J Strength Cond Res. 2000;14(2):207-213.
Jun 03, 2026
6 min read
A Letter To The Girl Newly Diagnosed With Endometriosis

A Letter To The Girl Newly Diagnosed With Endometriosis

Kadia Bielecki
You have known it was not normal for many years. If you’re reading this, you already know something’s off. Periods are not meant to debilitate you for more than a week every single month. In some ways knowing you have endometriosis can be empowering for your health and also your fertility. So, you’ve got the diagnosis. Endometriosis. If your story is anything like mine, you were dismissed, told it’s “just bad periods,” handed a heating pad and an anti-inflammatory that barely touched the pain. Sound familiar? I remember the day I got my first period. It was 6th grade, I came home for lunch and saw the blood. I was handed a thick pad and walked back to school for the afternoon. OK it was the 90’s. https://youtube.com/shorts/4uaaKU-vGP0?si=NRIUj7cyPiSuVMwL Within months, the gut-wrenching, curl-up-in-a-ball cramps, headaches, GI issues and brain fog started. I begged my mom to give me a pill to make this end forever. I was a dancer. Manoeuvring what to wear became difficult. It was embarrassing wearing my tight fitted leotard with the bloating visible from all the inflammation. Fast forward to my 20’s, the work meetings were the worst. Long winded bosses while I prayed my tampon did not leak and hoped the anti-inflammatory would kick in soon, all while pretending not to be distracted. Why didn’t we talk about our pain? It wasn’t until I wanted kids that the full impact of this thing hit me like a truck. Turns out, it wasn’t just “bad periods.” It was a full-time job trying to conceive, research, advocate for myself, and fight for the care I deserved. The good news is we have come a long way since the 90’s in managing the symptoms and impacts of endometriosis. I am lucky to have two amazing kids, however the road to this point was not easy or mapped out for me. Endometriosis is a tricky condition that is different for everybody. Demand the care you deserve. You’re not alone in this fight. There’s a whole army of us out here! Steps to Take Back Control Managing endometriosis isn’t easy, but there are actionable steps you can take to regain some power over your health: 1.    Eat an Anti-Inflammatory Diet [1] Nutrition plays a significant role in managing endometriosis symptoms. Some foods can ease inflammation and reduce pain during flare-ups: •       Turmeric: Add this anti-inflammatory powerhouse to tea or almond milk. [2] •       Leafy Greens: Spinach, kale, and Swiss chard are rich in magnesium, which can support with muscle cramps. [3] •       Omega-3 Fatty Acids: Found in salmon, walnuts, and chia seeds, these fats support inflammatory processes. [4] •       Berries and Citrus Fruits: Packed with antioxidants to strengthen your body’s defenses. [5] 2.    Supplements [6, 7, 8] Certain supplemental ingredients are gaining attention in conversations around endometriosis support. Ingredients such as ginger, N-acetyl cysteine (NAC), and palmitoylethanolamide (PEA) are being explored for their potential roles in inflammatory balance, oxidative stress support, and pain modulation within the body. While research is still evolving, many practitioners now incorporate these types of ingredients as part of a broader, individualized support plan alongside nutrition and lifestyle approaches. 3.    Heat [9] Heat therapy is one of the most commonly used non-pharmacological tools for managing endometriosis-related pelvic pain. Research suggests that applying heat to the lower abdomen may help relax pelvic muscles, improve blood flow, and reduce pain signals, which can provide temporary relief from cramping and pelvic discomfort associated with endometriosis. Some studies have even found that heat can offer pain relief comparable to certain over-the-counter medications for menstrual pain, making it a simple and accessible supportive strategy for many individuals living with chronic pelvic pain. 4.    Physical & Manual Therapies Beyond heat, a range of physical and manual approaches can support pain management and improve daily function. A 2025 systematic review and meta-analysis found that physical rehabilitation, including therapeutic exercise and manual therapy-based interventions, produced significant improvements in pain and quality of life in people with endometriosis. [10] •       TENS (Transcutaneous Electrical Nerve Stimulation): A portable, non-invasive device that delivers gentle electrical pulses through pads placed on the skin. Studies have shown improvements in chronic pelvic pain and quality of life as a complementary tool for endometriosis-related pain. [11] •       Gentle Movement: Low-impact activities such as walking, swimming, Pilates, and yoga can reduce pain, regulate inflammation, and support mental health. A systematic review of randomized controlled trials found that physical activity significantly improved both physical and psychological symptoms in women with endometriosis. [12] •       Arvigo Massage: An external abdominal massage technique derived from traditional Maya healing practices, Arvigo massage is believed to support pelvic circulation, improve alignment of pelvic and abdominal organs, and assist with the release of adhesions. While formal clinical evidence remains limited, many practitioners incorporate it into a broader pelvic health plan. 5.    Pelvic Floor Physiotherapy [13] Pelvic floor physiotherapy is another supportive tool that many individuals with endometriosis find helpful as part of a comprehensive care plan. Chronic pelvic pain can sometimes contribute to tension, guarding, and dysfunction within the pelvic floor muscles, which may worsen discomfort over time. Pelvic physiotherapists work to help improve muscle tension, mobility, pain patterns, posture, and nervous system regulation through individualized treatment approaches. For many people, this becomes an important part of feeling more connected to and supported in their body again. 6.    Mind-Body & Mental Health Support Living with a chronic pain condition like endometriosis takes a real toll on mental and emotional wellbeing. A growing body of research supports addressing this side of the disease alongside the physical. •       Acupuncture: A 2024 systematic review and meta-analysis found that acupuncture significantly reduced pain severity in people with endometriosis-related pain and improved response rates compared to controls. [14] •       Mindfulness & Meditation: Mindfulness-based interventions have shown significant and lasting effects on pain levels, wellbeing, and daily functionality in people with endometriosis, with some studies showing benefits maintained years after the intervention. [15] •       Counseling & Psychotherapy: Psychological approaches including cognitive behavioural therapy (CBT), self-care counselling, and psychotherapy have shown promise in improving quality of life, reducing anxiety and depression, and building pain coping strategies for people with endometriosis. [16] 7.    Plan for Fertility - Your Way [17] For some individuals with endometriosis, thinking about fertility can feel overwhelming, but it’s important to remember that fertility journeys are highly individual. Research shows that while endometriosis can be associated with challenges related to ovulation, inflammation, and implantation, many people with endometriosis are still able to conceive naturally or with additional support when needed. Having open conversations with a healthcare provider early on can help individuals better understand their options, timelines, and what proactive fertility planning may look like for them. 8.    Advocate for Your Care Endometriosis symptoms are often minimized or dismissed, which can leave many people feeling unheard or discouraged during their healthcare journey. Advocating for your own care may look like tracking symptoms, asking questions, seeking second opinions when necessary, and working with healthcare providers who take your concerns seriously. Your pain and experiences deserve attention, and feeling informed and supported can make a meaningful difference when navigating a chronic condition like endometriosis. You’re Not Alone You are not alone. You are part of a larger community building awareness and advocating for better and sooner treatment options. It is no longer acceptable for women to quietly exit from their life for a week each month in order to manage this condition. There are options for you to take control now as well as plan for the future. References 1. Barnard, Neal D., et al. ‘Nutrition in the Prevention and Treatment of Endometriosis: A Review’. Frontiers in Nutrition, vol. 10, Feb. 2023, p. 1089891. https://doi.org/10.3389/fnut.2023.1089891. 2. El-Saadony, Mohamed T., et al. ‘Impacts of Turmeric and Its Principal Bioactive Curcumin on Human Health’. Frontiers in Nutrition, vol. 9, Jan. 2023, p. 1040259. https://doi.org/10.3389/fnut.2022.1040259. 3. Fatima, Ghizal, et al. ‘Magnesium Matters: A Comprehensive Review of Its Vital Role in Health and Diseases’. Cureus, Oct. 2024. https://doi.org/10.7759/cureus.71392. 4. Zivkovic, Angela M., et al. ‘Dietary Omega-3 Fatty Acids Aid in the Modulation of Inflammation and Metabolic Health’. California Agriculture, vol. 65, no. 3, July 2011, pp. 106–11. https://doi.org/10.3733/ca.v065n03p106. 5. Maqsood, Sammra, et al. ‘Fruit-Based Diet and Gut Health: A Review’. Food Science & Nutrition, vol. 13, no. 5, May 2025, p. e70159. https://doi.org/10.1002/fsn3.70159. 6. Chen, Cong X., et al. ‘Efficacy of Oral Ginger (Zingiber officinale) for Dysmenorrhea: A Systematic Review and Meta-Analysis’. Evidence-Based Complementary and Alternative Medicine, vol. 2016. https://pmc.ncbi.nlm.nih.gov/articles/PMC4871956/. 7. Porpora, Maria Grazia, et al. ‘A Promise in the Treatment of Endometriosis: An Observational Cohort Study on Ovarian Endometrioma Reduction by N-Acetylcysteine’. Evidence-Based Complementary and Alternative Medicine, 2013. https://doi.org/10.1155/2013/240702. 8. Stochino Loi, E., et al. ‘Effect of Ultramicronized-Palmitoylethanolamide and Co-Micronized Palmitoylethanolamide/Polydatin on Chronic Pelvic Pain and Quality of Life in Endometriosis Patients: An Open-Label Pilot Study’. International Journal of Women’s Health, vol. 11, 2019, pp. 443–449. https://doi.org/10.2147/IJWH.S204603. 9. Armour, Mike, et al. ‘Self-Management Strategies amongst Australian Women with Endometriosis: A National Online Survey’. BMC Complementary and Alternative Medicine, vol. 19, no. 1, Dec. 2019, p. 17. https://doi.org/10.1186/s12906-019-2431-x. 10. Sobhani, Marzieh, et al. ‘Impact of Physical Rehabilitation on Endometriosis and Adenomyosis-Related Symptoms: A Systematic Review and Meta-Analysis’. Journal of Clinical Medicine, 2025. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12692515/. 11. Mira, Tatiana A. A., et al. ‘Effectiveness of Complementary Pain Treatment for Women with Deep Endometriosis through Transcutaneous Electrical Nerve Stimulation (TENS): Randomized Controlled Trial’. European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 194, 2015, pp. 1–6. https://doi.org/10.1016/j.ejogrb.2015.07.001. 12. Liu, Xinghui, et al. ‘The Effectiveness and Safety of Physical Activity and Exercise on Women with Endometriosis: A Systematic Review and Meta-Analysis’. PLOS ONE, 2025. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824993/. 13. Can, Gökçe, et al. ‘Physiotherapy for Endometriosis-Associated Pelvic Pain: A Systematic Review and Meta-Analysis’. Pain Medicine, July 2025. https://doi.org/10.1093/pm/pnaf083. 14. Chen, Cong, et al. ‘Acupuncture for Clinical Improvement of Endometriosis-Related Pain: A Systematic Review and Meta-Analysis’. Archives of Gynecology and Obstetrics, vol. 310, no. 4, Oct. 2024, pp. 2101–2114. https://doi.org/10.1007/s00404-024-07675-z. 15. Kold, M., et al. ‘Mindfulness-Based Psychological Intervention for Coping with Pain in Endometriosis’. Acta Obstetricia et Gynecologica Scandinavica, 2012. Referenced in: Perez-Herrezuelo, Irene, et al. ‘Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review’. International Journal of Environmental Research and Public Health, 2023. https://pmc.ncbi.nlm.nih.gov/articles/PMC9948268/. 16. Fernandez-Jimenez, M. C., et al. ‘Effectiveness of Psychological Interventions in Endometriosis: A Systematic Review with Meta-Analysis’. Frontiers in Psychology, vol. 15, 2024. https://doi.org/10.3389/fpsyg.2024.1457842. 17. Llarena, Natalia C., et al. ‘Fertility Preservation in Women With Endometriosis’. Clinical Medicine Insights: Reproductive Health, vol. 13, Jan. 2019, p. 1179558119873386. https://doi.org/10.1177/1179558119873386.
Jun 01, 2026
8 min read
Micronutrients: The Nutrients Many People Are Still Missing - Even With a “Healthy” Diet

Micronutrients: The Nutrients Many People Are Still Missing - Even With a “Healthy” Diet

Kadia Bielecki
We hear a lot about protein, greens powders, and wellness trends. But one of the biggest conversations happening quietly in nutrition research right now is something far more foundational: micronutrient insufficiency. Even people who eat relatively well may still fall short on key vitamins and minerals involved in energy production, immune signaling, neurological function, bone metabolism, and cellular repair [1,2]. And unlike macronutrients like protein, fats, and carbohydrates, micronutrients often work behind the scenes. You may not “feel” them immediately - but they help support nearly every major system in the body. What Are Micronutrients? Micronutrients are vitamins and minerals the body requires in smaller amounts to support normal physiological function. These include nutrients like: Vitamin D Magnesium Folate Zinc Selenium Vitamin B12 Vitamin K2 They help support processes related to: Cellular energy production Nervous system signaling Bone and mineral metabolism Immune health Mood and cognitive function DNA synthesis and repair [1,3] The challenge is that modern diets, stress, food quality, restrictive eating patterns, and lifestyle factors can all impact intake and utilization. Why Nutrient Gaps Are More Common Than Many People Think Nutrient insufficiency doesn’t necessarily mean a severe deficiency. Often, it simply means the body may not consistently receive optimal amounts of certain nutrients needed to support everyday function over time [2]. Research continues to show that common nutrient gaps may exist even in developed countries, particularly for nutrients like: Vitamin D Magnesium Folate Zinc Vitamin B12 [4,5] This can happen for several reasons: Food Quality Has Changed Modern agricultural practices and food processing can influence nutrient density compared to historical food supplies [6]. Stress Increases Nutrient Demand Psychological and physical stress may increase the body’s utilization of certain nutrients involved in nervous system regulation and energy metabolism, particularly magnesium and B vitamins [7]. Restrictive Diets Can Leave Gaps Plant-based diets, highly restrictive eating patterns, low-calorie diets, or inconsistent eating habits can sometimes make it harder to consistently obtain sufficient micronutrients from food alone [8]. Absorption Matters Too It’s not just about what you consume - it’s also about what your body can absorb and utilize. Certain forms of nutrients appear to have better bioavailability than others [9]. The Nutrients Getting the Most Attention Right Now Magnesium - One of the Most Commonly Under-Consumed Nutrients Magnesium is involved in more than 300 enzymatic reactions in the body, including muscle function, nervous system signaling, energy metabolism, and bone health [10]. Yet research suggests magnesium intake remains below recommended levels for many adults [11]. Some forms, such as magnesium malate, are often selected for their bioavailability and gastrointestinal tolerability. Vitamin D3 + K2 - A Nutritional Partnership Vitamin D helps support calcium absorption and immune function, while vitamin K2 helps direct calcium toward bones and away from soft tissues [12]. This is why many practitioners now view these nutrients as complementary rather than separate conversations. Vitamin D insufficiency also remains widespread globally, particularly in colder climates and indoor populations [13]. Methylated B Vitamins - Supporting Cellular Function Nutrients like folate, vitamin B6, and vitamin B12 help support: DNA synthesis Red blood cell formation Neurological function Energy metabolism [14] Some supplement formulations now utilize methylated forms, such as methylcobalamin (B12) and methylfolate, which are biologically active forms already usable by the body. Zinc + Selenium - Immune and Cellular Support Zinc and selenium are involved in antioxidant systems, immune signaling, thyroid physiology, and cellular protection mechanisms [15,16]. Zinc plays a role in maintaining skin integrity and immune cell activity, while selenium contributes to antioxidant defense systems and thyroid hormone metabolism. These nutrients are small in quantity - but essential in impact. Why “More” Isn’t Always Better One of the biggest misconceptions in the supplement industry is that bigger formulas automatically mean better formulas. But many modern practitioners are beginning to move away from the “kitchen sink” multivitamin approach. More ingredients does not always mean better absorption, better balance, or better outcomes. In fact, some nutrients are highly individualized. Calcium Calcium needs can vary significantly depending on diet, age, medications, and health status. Many people obtain meaningful calcium intake through food, making blanket supplementation less appropriate for everyone [17]. Calcium can also interfere with the absorption of other minerals when combined in larger amounts within broad multivitamin formulations. This is one reason some newer foundational formulas choose not to include calcium, allowing for more individualized supplementation based on personal dietary intake and needs. Additionally, more calcium is not always better. Excessive calcium supplementation may not be appropriate for everyone and should be personalized where possible [17]. Iron Iron requirements differ substantially between individuals based on life stage, sex, menstrual status, and overall health. Routine iron supplementation is not appropriate for everyone and is often best personalized [18]. Iron is also commonly recommended away from certain foods, minerals, and supplements because absorption can be influenced by what it is taken alongside. This is another reason many newer foundational multivitamin formulations leave iron as a separate, individualized conversation rather than including it universally. This is why some newer multivitamin formulations focus instead on foundational nutrients that are more commonly under-consumed, while leaving nutrients like iron and calcium to be tailored individually. Food Still Comes First Supplements should never replace a nutrient-dense diet. Many foundational nutrients are naturally found in foods like: Leafy greens Nuts and seeds Legumes Mushrooms Seafood Eggs Cruciferous vegetables Whole grains But consistency can be difficult. Busy schedules, stress, travel, convenience foods, appetite changes, and dietary restrictions can all make perfect nutrition unrealistic at times. That’s where foundational nutritional support may help complement - not replace - healthy dietary patterns. The Bigger Picture Micronutrients may not be the most exciting part of wellness culture. They’re not trendy. They don’t usually promise overnight transformation. But they help support the systems your body depends on every single day. Energy production.Immune signaling.Cellular repair.Bone metabolism.Neurological balance. And while wellness trends constantly change, foundational nutrition tends to remain remarkably consistent. Sometimes the smartest approach is also the simplest: consistently supporting the basics. References  Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System - Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. https://doi.org/10.3390/nu12010236 Ames BN. Low Micronutrient Intake May Accelerate the Degenerative Diseases of Aging Through Allocation of Scarce Micronutrients by Triage. Proceedings of the National Academy of Sciences. 2006;103(47):17589-17594. https://doi.org/10.1073/pnas.0608757103 Calder PC. Nutrition, Immunity and COVID-19. BMJ Nutrition, Prevention & Health. 2020;3(1):74-92. https://doi.org/10.1136/bmjnph-2020-000085 Bird JK, Murphy RA, Ciappio ED, McBurney MI. Risk of Deficiency in Multiple Concurrent Micronutrients in Children and Adults in the United States. Nutrients. 2017;9(7):655. https://doi.org/10.3390/nu9070655 DiNicolantonio JJ, O’Keefe JH. Magnesium Deficiency in America: Underestimated and Underdiagnosed. Open Heart. 2018;5:e000668. https://doi.org/10.1136/openhrt-2017-000668 Davis DR, Epp MD, Riordan HD. Changes in USDA Food Composition Data for 43 Garden Crops, 1950 to 1999. Journal of the American College of Nutrition. 2004;23(6):669-682. https://doi.org/10.1080/07315724.2004.10719409 Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy - A Review. Nutrients. 2016;8(2):68. https://doi.org/10.3390/nu8020068 Melina V, Craig W, Levin S. Position of the Academy of Nutrition and Dietetics: Vegetarian Diets. Journal of the Academy of Nutrition and Dietetics. 2016;116(12):1970-1980. https://doi.org/10.1016/j.jand.2016.09.025 Schuchardt JP, Hahn A. Intestinal Absorption and Factors Influencing Bioavailability of Magnesium. Nutrients. 2017;9(10):1023. https://doi.org/10.3390/nu9101023 Gröber U, Schmidt J, Kisters K. Magnesium in Prevention and Therapy. Nutrients. 2015;7(9):8199-8226. https://doi.org/10.3390/nu7095388 Rosanoff A, Weaver CM, Rude RK. Suboptimal Magnesium Status in the United States: Are the Health Consequences Underestimated? Nutrition Reviews. 2012;70(3):153-164. https://doi.org/10.1111/j.1753-4887.2011.00465.x Khalil Z, Alam B, Akbarali HI, et al. Vitamin D and K2: The Emerging Group of Vitamins Required for Human Bone Health. Maturitas. 2021;143:1-9. https://doi.org/10.1016/j.maturitas.2020.08.007 Holick MF. Vitamin D Deficiency. New England Journal of Medicine. 2007;357:266-281. https://doi.org/10.1056/NEJMra070553 O’Leary F, Samman S. Vitamin B12 in Health and Disease. Nutrients. 2010;2(3):299-316. https://doi.org/10.3390/nu2030299 Read SA, Obeid S, Ahlenstiel C, Ahlenstiel G. The Role of Zinc in Antiviral Immunity. Advances in Nutrition. 2019;10(4):696-710. https://doi.org/10.1093/advances/nmz013 Avery JC, Hoffmann PR. Selenium, Selenoproteins, and Immunity. Nutrients. 2018;10(9):1203. https://doi.org/10.3390/nu10091203 Weaver CM, Heaney RP. Calcium in Human Health. Humana Press. 2006. Camaschella C. Iron-Deficiency Anemia. New England Journal of Medicine. 2015;372:1832-1843. https://doi.org/10.1056/NEJMra1401038
May 29, 2026
6 min read
What Happens During a Colposcopy? A Step-by-Step Guide to Expect

What Happens During a Colposcopy? A Step-by-Step Guide to Expect

Kadia Bielecki
Getting told you need a colposcopy can feel overwhelming - especially if it happens after an abnormal Pap test, a positive HPV result, or an abnormal HPV co-test. One of the most common things people search after hearing the word “colposcopy” is simple: what actually happens during the appointment? The good news is that a colposcopy is a very common procedure used to take a closer look at the cervix. While it can feel intimidating beforehand, understanding the process step-by-step often helps reduce some of the anxiety surrounding it. This guide walks through what a colposcopy is, why it’s done, what the procedure feels like, possible recovery symptoms, and common questions people ask before their appointment. What Is a Colposcopy? A colposcopy is a medical procedure where a healthcare provider uses a special magnifying device called a colposcope to closely examine the cervix, vagina, and vulva. The colposcope stays outside the body - it does not enter the vagina. The procedure is often recommended after: positive high-risk HPV screening results abnormal Pap test results abnormal Pap + HPV co-testing results persistent HPV infections ASC-US, LSIL, or other cervical screening abnormalities visible cervical changes or unexplained bleeding In many regions, cervical screening guidelines have shifted toward HPV-primary testing because high-risk HPV types are more strongly linked to cervical cell changes over time. This means some people are now referred for colposcopy even when their Pap test is normal, depending on the HPV strain detected and their screening history. The goal is to identify whether there are areas of cervical tissue that may need closer monitoring or biopsy. According to the American College of Obstetricians and Gynecologists, colposcopy is considered a standard follow-up tool after certain abnormal cervical screening results. Why Do People Get Referred for a Colposcopy? One of the biggest misconceptions online is that a colposcopy automatically means something serious is wrong. In reality, many people are referred simply because their healthcare provider wants a closer look at the cervix after screening results come back outside the typical range. Because cervical screening recommendations continue to evolve, referral pathways can vary slightly depending on age, country, province/state, HPV strain, and prior screening history. Common reasons include: HPV-positive screening results ASC-US or LSIL Pap results abnormal Pap + HPV co-testing results persistent abnormal cervical screening results cervical inflammation follow-up monitoring after previous abnormal cells Importantly, HPV is extremely common. Research suggests that most sexually active adults are exposed to HPV at some point in their lives. In many cases, the immune system clears the virus naturally over time. Step-by-Step: What Happens During a Colposcopy? 1. You’ll Lie Back Like a Standard Pelvic Exam The procedure usually begins similarly to a Pap test. You’ll lie on an exam table with your feet supported while a speculum is inserted into the vagina so the cervix can be seen. For many people, this part feels very similar to a routine cervical screening. 2. The Colposcope Stays Outside the Body The provider positions the colposcope a few inches away from the vaginal opening. It acts like a magnifying camera and light source to help visualize cervical tissue more clearly. The colposcope itself does not touch you. 3. A Vinegar-Like Solution Is Applied A mild acetic acid solution (similar to vinegar) is often applied to the cervix. This helps highlight areas of abnormal cells by temporarily turning them white. Some people notice: mild stinging coolness slight discomfort Others feel nothing at all. 4. A Biopsy May Be Taken If the provider notices areas they want to examine further, they may take a small tissue sample called a biopsy. This is often the part people feel most nervous about. Experiences vary significantly, but people commonly describe biopsy sensations as: a quick pinch pressure cramping brief sharp discomfort Some individuals experience very mild symptoms, while others find it more uncomfortable. Anxiety levels, individual pain sensitivity, inflammation, and where the biopsy is taken can all influence the experience. Biopsies are an important part of the colposcopy process because they allow abnormal-looking tissue to be examined more closely under a microscope. While the colposcopy itself helps identify areas of concern visually, the biopsy helps determine whether cervical cell changes are mild, moderate, or more significant, which can guide follow-up recommendations and monitoring. The entire procedure is often completed within 10-20 minutes. Does a Colposcopy Hurt? This is one of the most searched questions online. There is no single "normal" experience when it comes to colposcopy discomfort or pain. Some people report only mild discomfort similar to a Pap test, while others find parts of the procedure, particularly a biopsy, painful. Both experiences are valid. If you're concerned about pain, consider discussing this with your healthcare provider beforehand so they can explain what to expect and review any available comfort measures. You may feel: pressure from the speculum menstrual-like cramping a brief pinching sensation during biopsy emotional stress or nervousness Research has shown that anxiety before gynecological procedures is extremely common and can influence pain perception. Some people find it helpful to: take slow breaths during the procedure ask the provider to explain each step bring a pad for afterward schedule rest time after the appointment ask questions beforehand to reduce uncertainty WWhat Happens After a Colposcopy? Experiences vary considerably from person to person. Some people describe the biopsy as mild pressure or cramping, while others report moderate to significant pain during the tissue sample collection. Factors such as individual pain sensitivity, anxiety levels, cervical sensitivity, inflammation, and the location of the biopsy can all influence how the procedure feels. Because experiences can differ so widely, it's reasonable to discuss pain management options and ask questions about what to expect before your appointment. If a Biopsy Was Taken You may experience: spotting brown or black discharge mild cramping light bleeding for a few days A paste solution is sometimes applied to help stop bleeding, which can create dark-colored discharge afterward. Most providers recommend temporarily avoiding: tampons penetrative sex swimming vaginal products for a short period while the cervix heals. Most biopsy-related symptoms improve within a few days, though spotting or dark discharge can occasionally last up to a week. Many people are able to return to work, school, or regular daily activities the same day, although some prefer to rest afterward if cramping occurs. It can also be emotionally draining to wait for biopsy results. Depending on the clinic and whether samples were taken, results may take anywhere from several days to a few weeks to return. What Symptoms After a Colposcopy Are Normal? Common temporary symptoms include: light bleeding dark discharge mild pelvic discomfort spotting However, you should contact a healthcare provider if you experience: heavy bleeding fever severe pelvic pain foul-smelling discharge dizziness or worsening symptoms Questions You May Want to Ask at Your Appointment Many people feel more comfortable when they prepare questions ahead of time. Some helpful questions may include: Was a biopsy taken? When will results come back? What type of cervical changes were seen? What follow-up might be recommended? Are there activity restrictions afterward? What symptoms should I watch for? How often should I repeat screening? Why HPV Experiences Can Look Different Between People One thing that often creates confusion online is seeing very different HPV experiences shared across Reddit, TikTok, forums, and social media. Some people: Many HPV infections resolve on their own Do not develop abnormal cervical changes Only require routine monitoring Others may experience: persistent abnormal Pap tests repeat colposcopies cervical procedures prolonged monitoring Researchers believe many factors may influence immune resilience and cervical health patterns, including: smoking sleep quality chronic stress nutrition age microbiome health overall immune function This does not mean someone “caused” their HPV experience. HPV is complex, and every individual’s experience can look different. The Emotional Side of Colposcopy Anxiety A colposcopy appointment can bring up a lot emotionally: fear embarrassment uncertainty anxiety about results frustration around waiting Those feelings are extremely common. Having clear, evidence-based information ahead of time can sometimes make the process feel more manageable. Final Thoughts A colposcopy is a common follow-up procedure used to take a closer look at cervical tissue after certain cervical screening results. While the experience can feel intimidating beforehand, understanding the process step-by-step may help reduce some of the uncertainty. Most importantly, abnormal Pap tests and HPV-positive results are common - and a colposcopy is often simply part of monitoring cervical health carefully and proactively. As cervical screening guidelines continue to evolve toward HPV-primary testing and co-testing approaches, more people may encounter colposcopy as part of routine follow-up care. Understanding why the procedure is recommended, what biopsies help evaluate, and what recovery may look like can help make the experience feel less overwhelming. References American College of Obstetricians and Gynecologists. Colposcopy. Accessed May 22, 2026. National Cancer Institute. HPV and Cancer. Accessed May 22, 2026. Centers for Disease Control and Prevention. About Genital HPV Infection. Accessed May 22, 2026. Johns Hopkins Medicine. Colposcopy. Accessed May 22, 2026. Cleveland Clinic. Colposcopy. Accessed May 22, 2026.
May 27, 2026
7 min read
Why PMOS/PCOS Doesn’t Look the Same for Everyone

Why PMOS/PCOS Doesn’t Look the Same for Everyone

Kadia Bielecki
Irregular periods. Acne. Hair growth. Fatigue. Weight changes. Fertility struggles. For years, conversations around PCOS treated it like one single condition with one predictable experience. But many women quickly realize that’s not reality. Two people can both meet the criteria for PCOS - or what is increasingly being discussed in some clinical circles as PMOS (Polycystic Metabolic-Ovarian Syndrome) - and still have completely different symptoms, lab patterns, and health concerns. That’s because PCOS/PMOS is not believed to follow one single pathway. Instead, researchers and clinicians often describe different patterns that may contribute to how the condition presents [1]. Importantly, these are not official diagnoses or rigid “types.” They are simply ways of understanding the different drivers that may influence symptoms. And for many people, overlap between patterns is extremely common. Below, we break down some of the most commonly discussed PCOS/PMOS presentations in simple, clear language. What Is PMOS? You may have started seeing the term “PMOS” appear online recently. Some researchers and clinicians have proposed the name Polycystic Metabolic-Ovarian Syndrome as a way to better reflect the strong metabolic component often involved in PCOS [1]. The conversation is still evolving, and PCOS remains the official medical term used in current guidelines. However, the growing discussion around PMOS highlights an important point: this condition is often about far more than ovarian cysts alone. How Is PCOS Currently Diagnosed? Most clinicians still use the Rotterdam Criteria, which define PCOS based on the presence of at least two of the following three features (Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2004)[2]: Irregular or absent ovulation Signs of elevated androgens (such as acne, excess hair growth, or certain lab findings) Polycystic-appearing ovaries on ultrasound What’s important to understand is that these criteria help guide diagnosis - but they do not explain why symptoms may be happening or why experiences can vary so dramatically between individuals. Why Do Symptoms Look So Different From Person to Person? Hormones, metabolism, inflammation, stress signaling, genetics, sleep, nutrition, and lifestyle factors can all influence how PCOS/PMOS presents. This is one reason why some people primarily struggle with irregular cycles, while others notice acne, energy crashes, hair changes, or metabolic concerns. It’s also why a one-size-fits-all conversation around PCOS often leaves many women feeling confused or unseen. What Are Some Common PCOS/PMOS Patterns People Talk About? Again, these are not formal medical diagnoses or fixed “types.” They are simply commonly discussed patterns that researchers and clinicians may use to describe different symptom presentations. 1. The Metabolic or Insulin-Resistance Pattern This is one of the most commonly discussed PCOS presentations. Research suggests that many individuals with PCOS experience some degree of insulin resistance, even if they are not in a larger body size [3]. This pattern may overlap with: Energy crashes or fatigue Increased hunger or cravings Difficulty with weight regulation Blood sugar fluctuations Elevated fasting insulin markers This is also one reason why ingredients like inositol and berberine are frequently studied in the context of PCOS metabolic health. 2. The Inflammatory Pattern Emerging research suggests that inflammatory process may play a role in PCOS for some individuals [4]. This presentation may overlap with: Persistent fatigue Skin concerns Gut-related symptoms Brain fog General feelings of systemic stress or inflammation Inflammation is complex and influenced by many factors, including sleep, stress, nutrition, movement, and overall metabolic health. 3. The Stress or Adrenal-Influenced Pattern Some people with PCOS may show signs of androgen excess that appear to involve adrenal hormone pathways, particularly elevated DHEA-S. While the ovaries are often the main source of increased androgens in PCOS, research suggests that approximately 20-30% of people with PCOS may also have adrenal androgen excess, most often reflected through higher DHEA-S levels [5]. This pattern may overlap with high stress load, poor sleep, feeling “wired but tired,” anxiety or burnout symptoms, and hormonal symptoms that are not clearly tied to metabolic markers. Because adrenal androgen production is linked to ACTH signaling, cortisol metabolism, and broader stress-hormone regulation, clinicians may consider adrenal and nervous system factors as part of the larger PCOS picture - without treating this as a separate diagnosis or fixed “type” [5]. 4. The Post-Pill or Transitional Pattern Some women notice cycle irregularities, acne, or androgen-like symptoms after stopping hormonal birth control. In certain cases, this can temporarily resemble PCOS. This does not necessarily mean someone has developed permanent PCOS. Hormonal transitions can take time, especially in younger women or after long-term contraceptive use. Because symptoms can overlap, it’s important not to self-diagnose based solely on social media content or online checklists. Can You Fit Into More Than One Pattern? Absolutely. In fact, overlap is likely more common than fitting neatly into one category. Someone may experience insulin resistance and inflammation. Another person may have stress-related symptoms layered on top of metabolic concerns. Symptoms can also shift over time depending on age, stress levels, lifestyle factors, and hormonal transitions. This complexity is exactly why PCOS/PMOS conversations are moving away from overly simplistic approaches. Why Does This Matter? Understanding that PCOS/PMOS can present differently helps explain why experiences vary so widely - and why many women feel frustrated when generic advice doesn’t seem to reflect their reality. It also reinforces an important point: complex conditions are rarely explained by one pathway alone. Hormonal health is deeply interconnected with metabolism, inflammation, stress physiology, sleep, and overall health. The goal is not to label yourself with a “type,” but rather to better understand that your experience may not look exactly like someone else’s - and that does not make it less valid. References Teede, Helena J., et al. ‘Polyendocrine Metabolic Ovarian Syndrome, the New Name for Polycystic Ovary Syndrome: A Multistep Global Consensus Process’. The Lancet, May 2026, p. S0140673626007178. DOI.org (Crossref), https://doi.org/10.1016/S0140-6736(26)00717-8. Christ, Jacob P., and Marcelle I. Cedars. ‘Current Guidelines for Diagnosing PCOS’. Diagnostics, vol. 13, no. 6, Mar. 2023, p. 1113. DOI.org (Crossref), https://doi.org/10.3390/diagnostics13061113. Purwar, Ananya, and Shailesh Nagpure. ‘Insulin Resistance in Polycystic Ovarian Syndrome’. Cureus, Oct. 2022. DOI.org (Crossref), https://doi.org/10.7759/cureus.30351. Rudnicka, Ewa, et al. ‘Chronic Low Grade Inflammation in Pathogenesis of PCOS’. International Journal of Molecular Sciences, vol. 22, no. 7, Apr. 2021, p. 3789. DOI.org (Crossref), https://doi.org/10.3390/ijms22073789. Yildiz, Bulent O., and Ricardo Azziz. ‘The Adrenal and Polycystic Ovary Syndrome’. Reviews in Endocrine and Metabolic Disorders, vol. 8, no. 4, Dec. 2007, pp. 331–42. DOI.org (Crossref), https://doi.org/10.1007/s11154-007-9054-0.
May 25, 2026
5 min read
How to Shop the Farmers Market Like a Naturopath

How to Shop the Farmers Market Like a Naturopath

Kadia Bielecki
11 In-Season Foods to Support Your Immune Foundation There’s a certain way a naturopath shops a farmers market. Not by calories.Not by trends.And definitely not by whatever wellness food is going viral that week. Instead, the focus is often much simpler: what nutrients and plant compounds help support the body’s ability to function, repair, and respond well to everyday stressors? Because immune health is rarely built overnight. It’s shaped through consistent patterns - including the foods we come back to again and again. And this time of year, many of those foods are naturally in season. Think: dark leafy greens cruciferous vegetables antioxidant-rich fruits sulfur-containing plants fibre-rich seasonal produce carotenoid-rich vegetables These are the same categories that consistently appear in nutrition research around immune resilience, antioxidant support, and overall cellular health [1,2]. The good news? You don’t need a complicated routine to start incorporating more of them. Fresh, seasonal, and full of nutrients .A naturopathic approach to the farmers market isn’t about trends - it’s about building supportive habits with foods that nourish immune and cellular health over time. 🥦🍓✨ 1. Broccoli Sprouts - Tiny but Potent Broccoli sprouts may be small, but they’re packed with naturally occurring compounds called glucosinolates, which are studied for their role in antioxidant activity and cellular defense pathways [3]. They’re one of those ingredients that feels surprisingly easy to add once you start buying them. Easy ways to use them: Sprinkle onto avocado toast Add to salads or grain bowls Layer into sandwiches or wraps 2. Kale - A Farmers Market Staple for a Reason Kale delivers a combination of carotenoids, vitamin C, fibre, and polyphenols that support overall immune and antioxidant function [4]. It’s also one of the easiest greens to build meals around. Easy ways to use it: Massage with olive oil and lemon for a simple salad Toss into soups or pasta Blend into smoothies 3. Cabbage - The Underrated Cruciferous Vegetable Cabbage often gets overlooked beside trendier greens, but nutritionally, it brings a lot to the table. As part of the cruciferous vegetable family, cabbage contains sulfur-containing compounds that are studied in relation to detoxification pathways and overall cellular health [5]. Easy ways to use it: Add to crunchy slaws Sauté with garlic and olive oil Toss into tacos or rice bowls 4. Spinach - An Easy Source of Folate + Antioxidants Spinach provides folate, carotenoids, vitamin C, and iron - nutrients involved in normal cellular function and overall health maintenance [6]. It’s also one of the easiest “add-in” foods for busy weeks. Easy ways to use it: Blend into smoothies Add to omelets or eggs Toss into pasta or soups 5. Asparagus - Peak Spring Produce Asparagus is one of spring’s signature vegetables and naturally contains folate, fibre, and antioxidant compounds [7]. Folate plays an important role in DNA synthesis and normal cellular turnover, making it one of the foundational nutrients involved in overall cellular health. Easy ways to use it: Roast with olive oil and sea salt Add to pasta or risotto Grill alongside protein and vegetables 6. Strawberries - More Than Just a Sweet Snack Peak-season strawberries are rich in vitamin C and polyphenols, both of which are associated with antioxidant support [8]. They’re also one of the easiest seasonal swaps for more nutrient-dense snacking. Easy ways to use them: Add to yogurt bowls Blend into smoothies Eat fresh with nuts or seeds 7. Carrots - A Simple Source of Carotenoids Carrots are naturally rich in carotenoids, including beta-carotene, which the body can convert into vitamin A - a nutrient involved in immune function, skin health, and cellular maintenance [9]. They’re inexpensive, versatile, and easy to incorporate into everyday meals. Easy ways to use them: Roast with olive oil and herbs Add to salads or grain bowls Snack on with hummus or dips 8. Mushrooms - Functional Support for the Immune System Mushrooms contain naturally occurring beta-glucans, compounds that have been studied for their role in supporting normal immune signaling and immune response function [10]. This isn’t about “boosting” immunity overnight - it’s more about supporting healthy immune communication over time. Easy ways to use them: Add to eggs or stir fries Roast for grain bowls Toss into pasta or soups 9. Tomatoes - Rich in Lycopene Tomatoes are one of the most well-known dietary sources of lycopene, a carotenoid studied for its antioxidant activity and role in cellular health [11]. Interestingly, cooked tomato products often provide more bioavailable lycopene than raw tomatoes. Easy ways to use them: Add roasted tomatoes to pasta or bowls Use tomato sauce in soups or stews Toss cherry tomatoes into salads 10. Garlic Scapes - One of Spring’s Most Seasonal Finds Garlic scapes are part of the allium family and contain sulfur compounds associated with antioxidant and immune-supportive activity [12]. They also happen to be one of the best farmers market finds this time of year. Easy ways to use them: Blend into pesto Chop into sautés Add to roasted vegetables 11. Watercress - A Surprisingly Nutrient-Dense Green Watercress is packed with vitamins A, C, and K along with phytonutrients involved in antioxidant activity [13]. It has a peppery flavor that works surprisingly well in everyday meals. Easy ways to use it: Add to salads Layer into sandwiches Toss into wraps or bowls The Bigger Picture When you step back, a clear pattern emerges. Many of these seasonal foods naturally provide: vitamin C folate carotenoids fibre sulfur compounds polyphenols lycopene These nutrients and plant compounds repeatedly appear in conversations around immune health, antioxidant activity, and cellular support [1,2]. And while food is always the foundation, consistency can sometimes be challenging - especially during stressful seasons, busy schedules, or periods where nutrition becomes less predictable. That’s one reason why some people choose to complement a food-first approach with targeted nutritional support. Papillex was developed around a similar philosophy: combining evidence-informed nutrients and plant compounds that help support immune health and overall cellular wellness alongside foundational lifestyle habits. But the goal is never perfection. It’s simply building more supportive patterns over time. A More Practical Way to Shop You don’t need to overhaul your entire routine to make seasonal eating feel supportive. Sometimes it looks like: adding one leafy green to your grocery list trying one cruciferous vegetable this week choosing seasonal berries over ultra-processed snacks adding mushrooms, tomatoes, or garlic to one dinner Small additions. Repeated often. Because supportive nutrition is usually less about extremes - and more about consistency. References Calder, Philip C. “Nutrition, Immunity and COVID-19.” BMJ Nutrition, Prevention & Health, vol. 3, no. 1, 2020, pp. 74-92. https://doi.org/10.1136/bmjnph-2020-000085 Gombart, Adrian F., et al. “A Review of Micronutrients and the Immune System - Working in Harmony to Reduce the Risk of Infection.” Nutrients, vol. 12, no. 1, 2020, p. 236. https://doi.org/10.3390/nu12010236 Fahey, Jed W., et al. “Broccoli Sprouts: An Exceptionally Rich Source of Inducers of Enzymes That Protect against Chemical Carcinogens.” Proceedings of the National Academy of Sciences, vol. 94, no. 19, 1997, pp. 10367-10372. https://doi.org/10.1073/pnas.94.19.10367 Sikora, Elżbieta, et al. “The Antioxidant Activity of Selected Cruciferous Vegetables Subjected to Aquathermal Processing.” Food Chemistry, vol. 107, no. 1, 2008, pp. 55-59. https://doi.org/10.1016/j.foodchem.2007.07.023 Juritsch, Anthony F., and Régis Moreau. “Role of Soybean-Derived Bioactive Compounds in Inflammatory Bowel Disease.” Nutrition Reviews, vol. 76, no. 8, 2018, pp. 618-638. https://doi.org/10.1093/nutrit/nuy021 Iacobellis, Ilaria, et al. “Nutritional, Biochemical, and Functional Properties of Spinach Leaf-Enriched Dough: A Healthier Alternative to Conventional Pasta.” Foods, vol. 13, no. 22, 2024, p. 3608. https://doi.org/10.3390/foods13223608 Basu, Arpita, et al. “Strawberry As a Functional Food: An Evidence-Based Review.” Critical Reviews in Food Science and Nutrition, vol. 54, no. 6, 2014, pp. 790-806. https://doi.org/10.1080/10408398.2011.608174 Kishimoto, Yoshimi, et al. “Effects of Acute Strawberry Consumption on Serum Levels of Vitamin C and Folic Acid, the Antioxidant Potential of LDL and Blood Glucose Response: A Randomised Cross-over Controlled Trial.” Journal of Nutritional Science, vol. 12, 2023, p. e39. https://doi.org/10.1017/jns.2022.117 Tanumihardjo, Sherry A. “Carotenoids and Human Health.” Advances in Nutrition, vol. 4, no. 2, 2013, pp. 141-147. https://doi.org/10.3945/an.112.003046 Mirończuk-Chodakowska, Iwona, et al. “Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era.” Nutrients, vol. 13, no. 11, 2021, p. 3960. https://doi.org/10.3390/nu13113960 Story, Emily N., et al. “An Update on the Health Effects of Tomato Lycopene.” Annual Review of Food Science and Technology, vol. 1, 2010, pp. 189-210. https://doi.org/10.1146/annurev.food.102308.124120 Shang, Ao, et al. “Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.).” Foods, vol. 8, no. 7, 2019, p. 246. https://doi.org/10.3390/foods8070246 Panahi Kokhdan, Esmaeel, et al. “A Narrative Review on Therapeutic Potentials of Watercress in Human Disorders.” Evidence-Based Complementary and Alternative Medicine, vol. 2021, 2021, pp. 1-13. https://doi.org/10.1155/2021/5516450
May 22, 2026
6 min read

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